IS5485A - Karbóhýdrat afleiður - Google Patents

Karbóhýdrat afleiður

Info

Publication number
IS5485A
IS5485A IS5485A IS5485A IS5485A IS 5485 A IS5485 A IS 5485A IS 5485 A IS5485 A IS 5485A IS 5485 A IS5485 A IS 5485A IS 5485 A IS5485 A IS 5485A
Authority
IS
Iceland
Prior art keywords
carbohydrate derivatives
carbohydrate
derivatives
Prior art date
Application number
IS5485A
Other languages
English (en)
Other versions
IS2527B (is
Inventor
Adriaan Anton Van Boeckel Constant
Petitou Maurice
Duchaussoy Philippe
Maria Dreef-Tromp Cornelia
Egbertus Maria Basten Johannes
Original Assignee
Sanofi-Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis
Publication of IS5485A publication Critical patent/IS5485A/is
Publication of IS2527B publication Critical patent/IS2527B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IS5485A 1997-11-19 2000-05-09 Kolvetnisafleiður IS2527B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97203613 1997-11-19
PCT/EP1998/007518 WO1999025720A1 (en) 1997-11-19 1998-11-16 Carbohydrate derivatives

Publications (2)

Publication Number Publication Date
IS5485A true IS5485A (is) 2000-05-09
IS2527B IS2527B (is) 2009-07-15

Family

ID=8228942

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5485A IS2527B (is) 1997-11-19 2000-05-09 Kolvetnisafleiður

Country Status (33)

Country Link
US (1) US6174863B1 (is)
EP (1) EP1032579B1 (is)
JP (1) JP4364959B2 (is)
KR (1) KR100518497B1 (is)
CN (1) CN1177855C (is)
AR (1) AR017640A1 (is)
AT (1) ATE239030T1 (is)
AU (1) AU746959B2 (is)
BR (1) BRPI9804699B1 (is)
CA (1) CA2253113C (is)
CO (1) CO4990974A1 (is)
CZ (1) CZ293639B6 (is)
DE (1) DE69814140T2 (is)
DK (1) DK1032579T3 (is)
EE (1) EE04348B1 (is)
ES (1) ES2198081T3 (is)
HU (1) HU226685B1 (is)
ID (1) ID21287A (is)
IL (1) IL126893A (is)
IS (1) IS2527B (is)
NO (1) NO310723B1 (is)
NZ (1) NZ332834A (is)
PE (1) PE134799A1 (is)
PL (1) PL188229B1 (is)
PT (1) PT1032579E (is)
RU (1) RU2210573C2 (is)
SG (1) SG72889A1 (is)
SK (1) SK284134B6 (is)
TR (1) TR199802372A2 (is)
TW (1) TW448180B (is)
UA (1) UA49089C2 (is)
WO (1) WO1999025720A1 (is)
ZA (1) ZA9810559B (is)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI289566B (en) 1999-12-07 2007-11-11 N.V.Organon Antithrombotic compound
EP1353556A4 (en) * 2001-01-23 2009-09-09 Massachusetts Inst Technology SYNTHESIS OF HEPARIN AND OTHER GLYCOSAMINOGLYCANS IN SOLID PHASE AND SOLUTION PHASE
CN100513398C (zh) 2002-12-03 2009-07-15 Axys药物公司 作为因子viia抑制剂的2-(2-羟基联苯-3-基)-1h-苯并咪唑-5-甲脒衍生物
CN1317287C (zh) * 2003-04-18 2007-05-23 山东大学 一种多硫酸寡糖及其制备方法
KR101156273B1 (ko) * 2004-03-04 2012-06-13 프로젠 파마슈티칼즈 리미티드 황산화 올리고사카라이드 유도체
CN102046781A (zh) 2008-05-30 2011-05-04 动量制药公司 糖结构以及制造和使用此类结构的方法
WO2010029552A1 (en) * 2008-09-10 2010-03-18 Transpharma Medical Ltd. Transdermal delivery of oligosaccharides
WO2011014793A2 (en) * 2009-07-31 2011-02-03 Reliable Biopharmaceutical Corporation Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
CN103917552B (zh) * 2011-06-17 2017-03-29 卡博梅麦特斯公司 具有短半衰期和高活性的合成五糖
EP2578594A1 (en) 2011-10-04 2013-04-10 Sanofi Process of preparation of L-iduronic acid comprising a decarboxylation/intramolecular cyclisation tandem reaction
US9873712B2 (en) * 2014-10-03 2018-01-23 Amphastar Pharmaceuticals, Inc. Method of purifying idraparinux sodium
CN109134553B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN109134555B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN109134554B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
WO2021043631A1 (en) 2019-09-02 2021-03-11 Hepoligo Solutions Aps Intermediates useful for preparing iduronic acid containing di- and polysaccharides
WO2021211441A1 (en) * 2020-04-13 2021-10-21 The Board Of Regents Of The University Of Oklahoma Modified sugar polymers with low anticoagulant activity and therapeutic activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2564468B1 (fr) * 1984-05-16 1994-12-23 Choay Sa Nouveaux oligosaccharides, leur preparation par voie de synthese et leurs applications biologiques
EP0300099A1 (en) * 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
DK0454220T3 (da) * 1990-04-23 1993-11-22 Sanofi Elf Carbohydratderivater omfattende en trisaccharidenhed
IL102758A (en) * 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them

Also Published As

Publication number Publication date
HU9802663D0 (en) 1999-01-28
EP1032579A1 (en) 2000-09-06
IL126893A (en) 2003-05-29
EE04348B1 (et) 2004-08-16
BRPI9804699B1 (pt) 2016-07-12
SK284134B6 (sk) 2004-09-08
EE200000301A (et) 2001-12-17
IL126893A0 (en) 1999-09-22
SK7362000A3 (en) 2000-10-09
CA2253113A1 (en) 1999-05-19
ES2198081T3 (es) 2004-01-16
CN1222524A (zh) 1999-07-14
EP1032579B1 (en) 2003-05-02
BR9804699A (pt) 2000-12-26
NZ332834A (en) 2000-01-28
CN1177855C (zh) 2004-12-01
SG72889A1 (en) 2000-05-23
JP4364959B2 (ja) 2009-11-18
NO310723B1 (no) 2001-08-20
HUP9802663A3 (en) 2000-04-28
PL188229B1 (pl) 2004-12-31
AU746959B2 (en) 2002-05-09
KR19990045312A (ko) 1999-06-25
TR199802372A2 (xx) 1999-06-21
IS2527B (is) 2009-07-15
JPH11217394A (ja) 1999-08-10
DE69814140D1 (de) 2003-06-05
NO985365D0 (no) 1998-11-18
PT1032579E (pt) 2003-08-29
UA49089C2 (uk) 2002-09-16
WO1999025720A1 (en) 1999-05-27
AR017640A1 (es) 2001-09-12
AU9324298A (en) 1999-06-17
ZA9810559B (en) 1999-05-15
ID21287A (id) 1999-05-20
CA2253113C (en) 2008-06-17
ATE239030T1 (de) 2003-05-15
PE134799A1 (es) 2000-01-07
HUP9802663A2 (hu) 1999-06-28
DK1032579T3 (da) 2003-08-25
HK1028406A1 (en) 2001-02-16
HU226685B1 (en) 2009-06-29
DE69814140T2 (de) 2004-04-08
CZ293639B6 (cs) 2004-06-16
CO4990974A1 (es) 2000-12-26
CZ376198A3 (cs) 1999-06-16
KR100518497B1 (ko) 2005-12-16
US6174863B1 (en) 2001-01-16
TW448180B (en) 2001-08-01
RU2210573C2 (ru) 2003-08-20
PL329789A1 (en) 1999-05-24
NO985365L (no) 1999-05-20

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