IS5497A - Bífenýlamidínafleiður - Google Patents

Bífenýlamidínafleiður

Info

Publication number: IS5497A
Authority: IS; Iceland
Prior art keywords: bífenýlamidínafleiður; chem; pharmaceutically acceptable; general formula; acceptable salt
Prior art date: 1997-11-20

Application number

IS5497A

Other languages

English (en)

Inventor

Takano Yasunobu

Nakada Tomohisa

Hara Takayuki

Sugiura Satoshi

Tsutsumi Takaharu

Takarada Reiko

Takazawa Yoshiharu

Original Assignee

Teijin Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-20

Filing date

2000-05-15

Publication date

2000-05-15

2000-05-15 Application filed by Teijin Limited filed Critical Teijin Limited

2000-05-15 Publication of IS5497A publication Critical patent/IS5497A/is

Links

LNUYLGUBVHEHEL-UHFFFAOYSA-N 2-phenylbenzenecarboximidamide Chemical class NC(=N)C1=CC=CC=C1C1=CC=CC=C1 LNUYLGUBVHEHEL-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/18—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Diabetes (AREA)
Hematology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IS5497A 1997-11-20 2000-05-15 Bífenýlamidínafleiður IS5497A (is)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP31969897		1997-11-20
JP12749898		1998-05-11
PCT/JP1998/005209 WO1999026918A1 (en)	1997-11-20	1998-11-19	Biphenylamidine derivatives

Publications (1)

Publication Number	Publication Date
IS5497A true IS5497A (is)	2000-05-15

Family

ID=26463455

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5497A IS5497A (is)	1997-11-20	2000-05-15	Bífenýlamidínafleiður

Country Status (28)

Country	Link
US (1)	US6706745B1 (is)
EP (1)	EP1043310B1 (is)
KR (1)	KR100581506B1 (is)
CN (1)	CN1150162C (is)
AT (1)	ATE268751T1 (is)
AU (1)	AU744567B2 (is)
BG (1)	BG63536B1 (is)
BR (1)	BR9814983A (is)
CA (1)	CA2310331A1 (is)
DE (1)	DE69824450T2 (is)
DK (1)	DK1043310T3 (is)
EE (1)	EE04564B1 (is)
ES (1)	ES2218866T3 (is)
HR (1)	HRP20000304B1 (is)
HU (1)	HUP0100085A3 (is)
ID (1)	ID24846A (is)
IL (1)	IL136100A (is)
IS (1)	IS5497A (is)
NO (1)	NO20002589L (is)
NZ (1)	NZ504407A (is)
PL (1)	PL340658A1 (is)
PT (1)	PT1043310E (is)
RU (1)	RU2197478C2 (is)
SK (1)	SK7612000A3 (is)
TR (1)	TR200001452T2 (is)
TW (1)	TW523504B (is)
UA (1)	UA52797C2 (is)
WO (1)	WO1999026918A1 (is)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU736112B2 (en) *	1997-11-20	2001-07-26	Teijin Limited	Biphenylamidine derivatives
US6676968B1 (en)	1999-01-28	2004-01-13	Teijin Limited	Release-regulating preparations comprising biphenyldiamine derivatives
WO2000069811A1 (en) *	1999-05-17	2000-11-23	Teijin Limited	Cyanobiphenyl derivatives
US20020065303A1 (en) *	2000-02-01	2002-05-30	Bing-Yan Zhu	Bivalent phenylene inhibitors of factor Xa
AU2001292331B2 (en) *	2000-10-04	2007-01-18	Kissei Pharmaceutical Co., Ltd.	5-amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing the same and intermediates for their preparation
US6316475B1 (en) *	2000-11-17	2001-11-13	Abbott Laboratories	Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications
US20040072866A1 (en) *	2001-01-26	2004-04-15	Takayuki Hara	Process for preparation of cyanophenylbenzoic acid derivatives
KR20030069226A (ko) *	2001-01-29	2003-08-25	데이진 가부시키가이샤	벤즈아미딘 유도체 및 이의 제조 방법
AR035425A1 (es) *	2001-01-30	2004-05-26	Teijin Ltd	Cristal de diclorhidrato del acido 3-(3-amidinofenil)-5-[({[1-(iminoetil)-4-piperidil]metil}amino)metil]benzoico y proceso para prepararlo
JPWO2002060448A1 (ja) *	2001-01-30	2004-05-27	帝人株式会社	医薬組成物
EP1443041A4 (en) *	2001-11-09	2006-06-07	Kissei Pharmaceutical	5-AMIDINO-2-HYDROXYBENZENE-SULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THEM, THEIR MEDICAL USE AND INTERMEDIATE PRODUCTS USED IN THEIR PRODUCTION
US6949668B2 (en)	2001-11-30	2005-09-27	Teijin Limited	Process for producing 5-(3-cyanophenyl)-3-formylbenzoic acid compound
EP1569912B1 (en)	2002-12-03	2015-04-29	Pharmacyclics, Inc.	2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
ES2393924T3 (es) *	2004-06-30	2013-01-02	Toyama Chemical Co., Ltd.	Derivado de arilamidina, sal del mismo y antifúngico que lo contiene
US9028867B2 (en)	2005-08-18	2015-05-12	Teijin Pharma Limited	Formulation having accurate dose-dividing function
CA2619745A1 (en)	2005-08-18	2007-02-22	Teijin Pharma Limited	Tablet with multiple drug-containing sections
PE20070698A1 (es)	2005-11-14	2007-08-17	Teijin Pharma Ltd	Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol
CA2986083A1 (en)	2015-06-11	2016-12-15	Basilea Pharmaceutica International AG	Efflux-pump inhibitors and therapeutic uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2550192B1 (fr) *	1983-08-03	1986-04-04	Sanofi Sa	Nouveaux derives de la benzamidine a activite antimicrobienne, leur procede de preparation, leur utilisation en tant que medicaments desinfectants ou conservateurs
DE4102024A1 (de)	1991-01-24	1992-07-30	Thomae Gmbh Dr K	Biphenylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DK0567967T3 (da)	1992-04-28	1996-11-18	Thomae Gmbh Dr K	Tritium-mærkede fibrinogen-receptor-antagonister, deres anvendelse og fremgangsmåde til deres fremstilling
DE4219158A1 (de) *	1992-06-11	1993-12-16	Thomae Gmbh Dr K	Biphenylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE19546452A1 (de) *	1995-12-13	1997-06-19	Boehringer Ingelheim Kg	Neue Phenylamidinderivate, Verfahren zu ihrer Herstelung und ihre Verwendung als Arzneimittel
JPH101467A (ja)	1996-06-13	1998-01-06	Banyu Pharmaceut Co Ltd	ビフェニルアミジン誘導体
DE19636689A1 (de) *	1996-09-10	1998-03-12	Boehringer Ingelheim Kg	Neue Benzamidinderivate
AU736112B2 (en) *	1997-11-20	2001-07-26	Teijin Limited	Biphenylamidine derivatives

1998
- 1998-11-19 TW TW087119208A patent/TW523504B/zh not_active IP Right Cessation
- 1998-11-19 EE EEP200000298A patent/EE04564B1/xx not_active IP Right Cessation
- 1998-11-19 DE DE69824450T patent/DE69824450T2/de not_active Expired - Fee Related
- 1998-11-19 HU HU0100085A patent/HUP0100085A3/hu unknown
- 1998-11-19 DK DK98954747T patent/DK1043310T3/da active
- 1998-11-19 CA CA002310331A patent/CA2310331A1/en not_active Abandoned
- 1998-11-19 NZ NZ504407A patent/NZ504407A/en unknown
- 1998-11-19 HR HR20000304A patent/HRP20000304B1/xx not_active IP Right Cessation
- 1998-11-19 SK SK761-2000A patent/SK7612000A3/sk unknown
- 1998-11-19 IL IL13610098A patent/IL136100A/xx not_active IP Right Cessation
- 1998-11-19 PL PL98340658A patent/PL340658A1/xx not_active Application Discontinuation
- 1998-11-19 WO PCT/JP1998/005209 patent/WO1999026918A1/ja not_active Ceased
- 1998-11-19 TR TR2000/01452T patent/TR200001452T2/xx unknown
- 1998-11-19 KR KR1020007005463A patent/KR100581506B1/ko not_active Expired - Fee Related
- 1998-11-19 BR BR9814983-0A patent/BR9814983A/pt not_active Application Discontinuation
- 1998-11-19 UA UA2000063535A patent/UA52797C2/uk unknown
- 1998-11-19 RU RU2000115947/04A patent/RU2197478C2/ru not_active IP Right Cessation
- 1998-11-19 CN CNB988132206A patent/CN1150162C/zh not_active Expired - Fee Related
- 1998-11-19 US US09/554,799 patent/US6706745B1/en not_active Expired - Fee Related
- 1998-11-19 EP EP98954747A patent/EP1043310B1/en not_active Expired - Lifetime
- 1998-11-19 ID IDW20000955A patent/ID24846A/id unknown
- 1998-11-19 ES ES98954747T patent/ES2218866T3/es not_active Expired - Lifetime
- 1998-11-19 AT AT98954747T patent/ATE268751T1/de not_active IP Right Cessation
- 1998-11-19 AU AU11740/99A patent/AU744567B2/en not_active Ceased
- 1998-11-19 PT PT98954747T patent/PT1043310E/pt unknown
2000
- 2000-05-15 IS IS5497A patent/IS5497A/is unknown
- 2000-05-17 BG BG104447A patent/BG63536B1/bg unknown
- 2000-05-19 NO NO20002589A patent/NO20002589L/no unknown

Also Published As

Publication number	Publication date
EP1043310A1 (en)	2000-10-11
AU1174099A (en)	1999-06-15
SK7612000A3 (en)	2001-05-10
US6706745B1 (en)	2004-03-16
TW523504B (en)	2003-03-11
IL136100A0 (en)	2001-05-20
NZ504407A (en)	2002-02-01
BG63536B1 (bg)	2002-04-30
HRP20000304B1 (en)	2005-08-31
RU2197478C2 (ru)	2003-01-27
UA52797C2 (uk)	2003-01-15
DE69824450D1 (de)	2004-07-15
HUP0100085A2 (hu)	2001-07-30
ID24846A (id)	2000-08-24
KR20010032259A (ko)	2001-04-16
BR9814983A (pt)	2000-10-03
CA2310331A1 (en)	1999-06-03
DK1043310T3 (da)	2004-10-25
TR200001452T2 (tr)	2004-12-21
NO20002589L (no)	2000-07-19
EP1043310B1 (en)	2004-06-09
HRP20000304A2 (en)	2002-02-28
BG104447A (en)	2001-01-31
IL136100A (en)	2005-05-17
AU744567B2 (en)	2002-02-28
CN1150162C (zh)	2004-05-19
EP1043310A4 (en)	2001-03-21
EE04564B1 (et)	2005-12-15
ATE268751T1 (de)	2004-06-15
PL340658A1 (en)	2001-02-12
WO1999026918A1 (en)	1999-06-03
NO20002589D0 (no)	2000-05-19
DE69824450T2 (de)	2005-09-29
ES2218866T3 (es)	2004-11-16
HUP0100085A3 (en)	2002-12-28
KR100581506B1 (ko)	2006-05-22
EE200000298A (et)	2001-08-15
PT1043310E (pt)	2004-10-29
CN1284059A (zh)	2001-02-14

Publication	Publication Date	Title
NO20002589D0 (no)	2000-05-19	Bifenylamidinderivater
ATE260255T1 (de)	2004-03-15	5-oxo-pyrrolidine-2-carbonsäure- hydroxamidderivate
WO2001019828A3 (en)	2001-10-04	Kinase inhibitors as therapeutic agents
ATE297203T1 (de)	2005-06-15	Antithrombotische mitteln
LU92113I2 (fr)	2013-02-12	Perampanel et ses dérivés pharmaceutiquement acceptables (FYCOMPA)
ATE306261T1 (de)	2005-10-15	Antithrombosemittel
DK0848004T3 (da)	2003-07-21	Pyrrolidinderivater med inhiberende aktivitet mod phospholipase A2
BR0014651A (pt)	2002-06-18	Inibidores de adesão de célula mediada por "alfa" l beta2
DE69426602D1 (de)	2001-02-22	2,3-diaminopropionsäurederivate
DK0807630T3 (da)	2003-09-01	Heterocykliske forbindelser
ATE271045T1 (de)	2004-07-15	Sauerstoffhaltige heterocyclische verbindungen
ATE278661T1 (de)	2004-10-15	Anthranilsäurederivate
DE60104697D1 (de)	2004-09-09	Sulfonamid-derivate
DE69623497D1 (de)	2002-10-10	1-methylcarbapenem-derivate
EP1152004A4 (en)	2002-01-23	PHOSPHONIC ACID DERIVATIVES HAVING CARBOXYPEPTIDASE B INHIBITOR ACTIVITY
MY129094A (en)	2007-03-30	Condensed polycyclic compounds
ES2185599T3 (es)	2003-05-01	Preparacion de intermediarios de la imidazodiacepina.
ES2149180T3 (es)	2000-11-01	Derivado de pirazolotiazolopirimidina.
EP1466900A4 (en)	2005-07-20	DERIVATIVES OF VITAMIN D-DOUBLE SUBSTITUTION
PL342826A1 (en)	2001-07-02	Derivatives of cycloalkenes, their production and application