IS5608A - Hröð stýranleg leysi sundrun á frumum fyrir greiningu - Google Patents

Hröð stýranleg leysi sundrun á frumum fyrir greiningu

Info

Publication number
IS5608A
IS5608A IS5608A IS5608A IS5608A IS 5608 A IS5608 A IS 5608A IS 5608 A IS5608 A IS 5608A IS 5608 A IS5608 A IS 5608A IS 5608 A IS5608 A IS 5608A
Authority
IS
Iceland
Prior art keywords
fragmentation
cells
analysis
controllable solvent
rapidly controllable
Prior art date
Application number
IS5608A
Other languages
English (en)
Inventor
L. Allbritton Nancy
E. Sims Christopher
W. Berns Michael
D. Meredith Gavin
B. Krasieva Tatiana
J. Tromberg Bruce
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of IS5608A publication Critical patent/IS5608A/is

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/06Hydrolysis; Cell lysis; Extraction of intracellular or cell wall material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44743Introducing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
IS5608A 1998-03-06 2000-08-29 Hröð stýranleg leysi sundrun á frumum fyrir greiningu IS5608A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/036,706 US6156576A (en) 1998-03-06 1998-03-06 Fast controllable laser lysis of cells for analysis
PCT/US1999/004595 WO1999045372A1 (en) 1998-03-06 1999-03-03 Fast controllable laser lysis of cells for analysis

Publications (1)

Publication Number Publication Date
IS5608A true IS5608A (is) 2000-08-29

Family

ID=21890154

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5608A IS5608A (is) 1998-03-06 2000-08-29 Hröð stýranleg leysi sundrun á frumum fyrir greiningu

Country Status (9)

Country Link
US (1) US6156576A (is)
EP (1) EP1060387A1 (is)
JP (1) JP2002505856A (is)
KR (1) KR20010074440A (is)
AU (1) AU2889199A (is)
CA (1) CA2322857A1 (is)
IL (1) IL138179A0 (is)
IS (1) IS5608A (is)
WO (1) WO1999045372A1 (is)

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US6335201B1 (en) * 1998-03-06 2002-01-01 The Regents Of The University Of California Method and apparatus for detecting enzymatic activity using molecules that change electrophoretic mobility
US7236888B2 (en) * 1998-03-06 2007-06-26 The Regents Of The University Of California Method to measure the activation state of signaling pathways in cells
US6740497B2 (en) * 1998-03-06 2004-05-25 The Regents Of The University Of California Method and apparatus for detecting cancerous cells using molecules that change electrophoretic mobility
EP0962524B1 (de) * 1998-05-27 2004-11-03 Micronas GmbH Verfahren und Vorrichtung zur intrazellulären Manipulation einer biologischen Zelle
US6464852B1 (en) * 1998-12-03 2002-10-15 State University Of New York At Stony Brook Multicapillary bundle for electrophoresis and detection for DNA
CA2392534A1 (en) 1999-11-30 2001-06-07 Oncosis Method and apparatus for selectively targeting specific cells within a cell population
EP2363828A1 (en) 2000-10-24 2011-09-07 Cyntellect, Inc. Device for selectively targeting cells within a three-dimensional specimen
US20020121443A1 (en) * 2000-11-13 2002-09-05 Genoptix Methods for the combined electrical and optical identification, characterization and/or sorting of particles
AU2002217839A1 (en) * 2000-11-22 2002-06-03 The Regents Of The University Of California A method to measure the activation state of signaling pathways in cells
US6815209B2 (en) * 2001-11-16 2004-11-09 Cornell Research Foundation, Inc. Laser-induced cell lysis system
AU2003234323A1 (en) * 2002-05-03 2003-11-17 The Regents Of The University Of California Fast electrical lysis of cells and rapid collection of the contents thereof using capillary electrophoresis
EP1545740A2 (en) * 2002-09-07 2005-06-29 Arizona Board of Regents Integrated apparatus and methods for treating liquids
US20050064137A1 (en) * 2003-01-29 2005-03-24 Hunt Alan J. Method for forming nanoscale features and structures produced thereby
US7767435B2 (en) * 2003-08-25 2010-08-03 University Of Washington Method and device for biochemical detection and analysis of subcellular compartments from a single cell
EP1668355A4 (en) 2003-08-28 2011-11-09 Celula Inc METHODS AND APPARATUS FOR SORTING CELLS USING AN OPTICAL SWITCH IN A MICROFLUIDIC CHANNEL NETWORK
US7425426B2 (en) 2004-03-15 2008-09-16 Cyntellect, Inc. Methods for purification of cells based on product secretion
JP2005333889A (ja) * 2004-05-27 2005-12-08 Cybox Co Ltd 細胞壊死方法及び細胞壊死装置
US7592139B2 (en) 2004-09-24 2009-09-22 Sandia National Laboratories High temperature flow-through device for rapid solubilization and analysis
KR100695160B1 (ko) 2004-10-19 2007-03-14 삼성전자주식회사 레이저 및 마이크로 자성 비드를 이용한 세포 또는바이러스의 신속한 파괴 방법 및 장치
KR20060046032A (ko) * 2004-10-19 2006-05-17 삼성전자주식회사 레이저 및 마이크로 자성 비드를 이용한 세포 또는바이러스의 신속한 파괴 방법 및 장치
EP1650297B1 (en) 2004-10-19 2011-04-13 Samsung Electronics Co., Ltd. Method and apparatus for the rapid disruption of cells or viruses using micro magnetic beads and laser
KR100601972B1 (ko) * 2004-11-03 2006-07-18 삼성전자주식회사 레이저와 비드를 이용한 상 분리에 의한 핵산의 정제 장치및 방법
KR100601974B1 (ko) 2004-11-25 2006-07-18 삼성전자주식회사 비드의 상이한 레이저 흡수에 의한 핵산의 정제 장치 및방법
WO2006069577A1 (en) * 2004-12-31 2006-07-06 Memsflow Aps Generation of pulsating pressure waves, e.g. for cell lysis
GB0508983D0 (en) 2005-05-03 2005-06-08 Oxford Gene Tech Ip Ltd Cell analyser
KR101157174B1 (ko) * 2005-11-24 2012-06-20 삼성전자주식회사 세포 또는 바이러스의 신속한 파괴 방법 및 장치
KR100829585B1 (ko) 2006-04-07 2008-05-14 삼성전자주식회사 표적 세포 분리 및 신속한 핵산 분리 방법 및 장치
US20080241843A1 (en) * 2006-12-21 2008-10-02 Stanford University Single-cell analysis systems, methods of counting molecules in a single-cell, cylindrical fluorescence detection systems
US8901487B2 (en) * 2007-07-20 2014-12-02 George Washington University Subcellular analysis by laser ablation electrospray ionization mass spectrometry
JP2012514477A (ja) * 2009-01-09 2012-06-28 イントレクソン コーポレイション 細胞の遺伝学的解析
KR20110108390A (ko) 2009-01-12 2011-10-05 신텔렉트 인코포레이티드 레이저로 매개된 박막 절개 및 세포 군체의 이동
WO2015048009A1 (en) * 2013-09-27 2015-04-02 Arizona Board Of Regents On Behale Of Arizona State University System and method for laser lysis
WO2015097858A1 (ja) * 2013-12-27 2015-07-02 株式会社日立製作所 生体分子解析装置
CN106461558B (zh) * 2014-05-26 2019-03-08 株式会社日立制作所 光学分析装置
JP6279081B2 (ja) * 2014-07-18 2018-02-14 株式会社日立製作所 光学分析装置
WO2016168429A1 (en) 2015-04-14 2016-10-20 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University Method and apparatus for extracting and collecting single cells from formalin-fixed paraffin embedded tissues
CN104765165B (zh) * 2015-04-20 2018-08-07 三峡大学 一种微球快速光悬浮的方法及装置
CN110736695A (zh) * 2016-09-30 2020-01-31 多伦多大学管理委员会 用于鉴定和靶向异质群体中的个体细胞以选择性提取细胞内容物的系统
JP7039261B2 (ja) * 2017-11-17 2022-03-22 株式会社日立製作所 組織切片の特定領域からの生体分子採取方法および装置
CN116171331A (zh) 2020-06-01 2023-05-26 德迈逊科技有限公司 用于基因组分析的装置和方法
TWI806062B (zh) * 2021-06-07 2023-06-21 新加坡商克雷多生醫有限公司 利用雷射打開細胞外層結構的方法及裝置
TWI785636B (zh) 2021-06-07 2022-12-01 新加坡商克雷多生醫有限公司 檢測卡匣
CN115505588A (zh) * 2021-06-07 2022-12-23 克雷多诊断生物医学私人有限公司 利用激光打开细胞外层结构的方法及装置
EP4177329A1 (en) 2021-11-08 2023-05-10 TECAN Trading AG Tracking of lysing at a location on a tissue section

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US4469098A (en) * 1978-12-18 1984-09-04 Davi Samantha K Apparatus for and method of utilizing energy to excise pathological tissue
CA2031716C (en) * 1989-12-07 1996-06-18 Hiroaki Misawa Laser microprocessing and the device therefor
US5071417A (en) * 1990-06-15 1991-12-10 Rare Earth Medical Lasers, Inc. Laser fusion of biological materials
CA2057506C (en) * 1990-12-13 2003-05-13 Keiji Sasaki Laser trapping and method for applications thereof
JP3233957B2 (ja) * 1991-11-21 2001-12-04 科学技術振興事業団 極微小レーザー光源の形成方法とレーザー発振方法
IL100664A0 (en) * 1992-01-15 1992-09-06 Laser Ind Ltd Method and apparatus for controlling a laser beam
SE500702C2 (sv) * 1992-04-07 1994-08-15 Staffan Birnbaum Sätt och anordning för optisk analys av prov separerade i tunna kapillärer
US5409586A (en) * 1992-08-26 1995-04-25 Hitachi, Ltd. Method for analyzing nucleic acid or protein and apparatus therefor
US5505831A (en) * 1993-01-26 1996-04-09 Bio-Rad Laboratories, Inc. Concentration of biological samples on a microliter scale and analysis by capillary electrophoresis
US5324401A (en) * 1993-02-05 1994-06-28 Iowa State University Research Foundation, Inc. Multiplexed fluorescence detector system for capillary electrophoresis
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US5565171A (en) * 1993-05-28 1996-10-15 Governors Of The University Of Alberta Continuous biochemical reactor for analysis of sub-picomole quantities of complex organic molecules
WO1995016910A1 (en) * 1993-12-17 1995-06-22 Perkin-Elmer Corporation Uncharged polymers for separation of biomolecules by capillary electrophoresis

Also Published As

Publication number Publication date
AU2889199A (en) 1999-09-20
EP1060387A1 (en) 2000-12-20
CA2322857A1 (en) 1999-09-10
WO1999045372A1 (en) 1999-09-10
IL138179A0 (en) 2001-10-31
JP2002505856A (ja) 2002-02-26
US6156576A (en) 2000-12-05
KR20010074440A (ko) 2001-08-04

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