IS5827A - Múskarín gerandefni og mótlyf - Google Patents

Múskarín gerandefni og mótlyf

Info

Publication number
IS5827A
IS5827A IS5827A IS5827A IS5827A IS 5827 A IS5827 A IS 5827A IS 5827 A IS5827 A IS 5827A IS 5827 A IS5827 A IS 5827A IS 5827 A IS5827 A IS 5827A
Authority
IS
Iceland
Prior art keywords
muskrin
antidotes
agonists
muskrin agonists
Prior art date
Application number
IS5827A
Other languages
English (en)
Inventor
Grewal Gurmit
Toy-Palmer Anna
Cai Xiong
Mark Latham George
Original Assignee
Ucb, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb, S.A. filed Critical Ucb, S.A.
Publication of IS5827A publication Critical patent/IS5827A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IS5827A 1998-08-18 2001-01-26 Múskarín gerandefni og mótlyf IS5827A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9697798P 1998-08-18 1998-08-18
PCT/US1999/018570 WO2000011001A1 (en) 1998-08-18 1999-08-16 Muscarinic agonists and antagonists

Publications (1)

Publication Number Publication Date
IS5827A true IS5827A (is) 2001-01-26

Family

ID=22260061

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5827A IS5827A (is) 1998-08-18 2001-01-26 Múskarín gerandefni og mótlyf

Country Status (30)

Country Link
US (5) US6093724A (is)
EP (1) EP1112272B1 (is)
JP (1) JP2002523416A (is)
KR (1) KR20010072784A (is)
CN (1) CN1312812A (is)
AR (1) AR020199A1 (is)
AT (1) ATE227724T1 (is)
AU (1) AU750566B2 (is)
BG (1) BG105256A (is)
BR (1) BR9913072A (is)
CA (1) CA2340946A1 (is)
CO (1) CO5130018A1 (is)
DE (1) DE69903961T2 (is)
EE (1) EE200100096A (is)
ES (1) ES2191455T3 (is)
HK (1) HK1038918A1 (is)
HU (1) HUP0103203A3 (is)
ID (1) ID27544A (is)
IL (1) IL141050A0 (is)
IS (1) IS5827A (is)
NO (1) NO20010804L (is)
NZ (1) NZ509762A (is)
PE (1) PE20000988A1 (is)
PL (1) PL346247A1 (is)
RU (1) RU2219179C2 (is)
SK (1) SK1892001A3 (is)
TR (1) TR200100462T2 (is)
WO (1) WO2000011001A1 (is)
YU (1) YU13301A (is)
ZA (1) ZA200100978B (is)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2001002306A0 (en) * 2000-10-19 2001-12-31 Pfizer Prod Inc Bridged piperazine derivatives.
GB0117950D0 (en) * 2001-02-16 2001-09-19 Aventis Pharma Inc Novel heterocyclic urea derivatives andd their use as dopamine D3 receptor ligands
WO2002094827A1 (en) * 2001-05-23 2002-11-28 Neurosearch A/S Fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
US20030064979A1 (en) * 2001-06-29 2003-04-03 Hansen Thomas Kruse Method of inhibiting PTP 1B and /or T-cell PTP and/or other PTPases with an Asp residue at position 48
US6828328B1 (en) * 2002-03-01 2004-12-07 Ucb S.A. Analgesic combination of muscarinic agonists
US7897766B2 (en) * 2005-09-23 2011-03-01 Abbott Laboratories Amino-aza-adamantane derivatives and methods of use
US8314119B2 (en) * 2006-11-06 2012-11-20 Abbvie Inc. Azaadamantane derivatives and methods of use
US8076350B2 (en) 2006-12-22 2011-12-13 Abbott Laboratories Spirocyclic azaadamantane derivatives and methods of use
CA2679876A1 (en) 2007-03-23 2008-10-02 Abbott Laboratories 4-substituted azaadamantane derivatives and methods of use thereof
CN101641356B (zh) * 2007-03-23 2012-09-05 雅培制药有限公司 氮杂金刚烷的乙酰胺和甲酰胺衍生物及其使用方法
WO2010145208A1 (en) * 2009-06-19 2010-12-23 Abbott Laboratories Diazahomoadamantane derivatives and methods of use thereof
EP3061821B1 (en) 2009-07-22 2019-07-10 Puretech Health LLC Compositions for treatment of disorders ameliorated by muscarinic receptor activation
US10265311B2 (en) 2009-07-22 2019-04-23 PureTech Health LLC Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
WO2011133920A1 (en) 2010-04-23 2011-10-27 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
CN103180321A (zh) * 2010-09-23 2013-06-26 Abbvie公司 氮杂金刚烷衍生物的一水合物
US8759380B2 (en) 2011-04-22 2014-06-24 Cytokinetics, Inc. Certain heterocycles, compositions thereof, and methods for their use
US11299481B2 (en) 2017-10-20 2022-04-12 Vanderbilt University Antagonists of the muscarinic acetylcholine receptor M4
EP3732163A4 (en) * 2017-12-20 2021-07-14 Vanderbilt University MUSCARIN M4 ACETYLCHOLIN RECEPTOR ANTAGONISTS
US10933020B2 (en) 2018-09-28 2021-03-02 Karuna Therapeutics, Inc. Compositions and methods for treating disorders ameliorated by muscarinic receptor activation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4739074A (en) * 1986-01-22 1988-04-19 Pennwalt Corporation Adamantane spiro-pyrrolidine derivatives
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
US5527813A (en) * 1990-08-21 1996-06-18 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
JPH06502616A (ja) * 1990-12-21 1994-03-24 メルク　シヤープ　エンド　ドーム　リミテツド 治療用化合物
US5955470A (en) * 1991-06-11 1999-09-21 Merrell Pharmaceuticals, Inc. Derivatives of amide analogs of certain methano bridged quinolizines
US5641791A (en) * 1991-08-13 1997-06-24 Novo Nordisk A.S Heterocyclic compounds and their preparation and use
RU2162469C2 (ru) * 1995-11-02 2001-01-27 Ньюросерч А/С Конденсированные тропановые производные в качестве ингибиторов обратного захвата нейромедиаторов
US5914338A (en) * 1996-04-02 1999-06-22 Novo Nordisk Heterocyclic compounds and their preparation and use
US5952339A (en) * 1998-04-02 1999-09-14 Bencherif; Merouane Pharmaceutical compositions and methods of using nicotinic antagonists for treating a condition or disorder characterized by alteration in normal neurotransmitter release
US5986100A (en) * 1998-04-02 1999-11-16 Crooks; Peter Anthony Pharmaceutical compositions and methods for use
US6057446A (en) * 1998-04-02 2000-05-02 Crooks; Peter Anthony Certain 1-aza-tricyclo [3.3.1-13,7 ] decane compounds

Also Published As

Publication number Publication date
HUP0103203A2 (hu) 2002-01-28
ATE227724T1 (de) 2002-11-15
US6251916B1 (en) 2001-06-26
ZA200100978B (en) 2002-02-05
NZ509762A (en) 2002-12-20
JP2002523416A (ja) 2002-07-30
CA2340946A1 (en) 2000-03-02
US20020045617A1 (en) 2002-04-18
HK1038918A1 (zh) 2002-04-04
EP1112272A1 (en) 2001-07-04
DE69903961D1 (de) 2002-12-19
EE200100096A (et) 2002-06-17
US6423842B1 (en) 2002-07-23
SK1892001A3 (en) 2001-11-06
KR20010072784A (ko) 2001-07-31
ES2191455T3 (es) 2003-09-01
TR200100462T2 (tr) 2001-09-21
PE20000988A1 (es) 2000-09-30
PL346247A1 (en) 2002-01-28
NO20010804L (no) 2001-04-11
AR020199A1 (es) 2002-05-02
NO20010804D0 (no) 2001-02-16
YU13301A (sh) 2005-06-10
ID27544A (id) 2001-04-12
US6093724A (en) 2000-07-25
US6323194B1 (en) 2001-11-27
IL141050A0 (en) 2002-02-10
BR9913072A (pt) 2001-05-15
HUP0103203A3 (en) 2002-10-28
EP1112272B1 (en) 2002-11-13
AU750566B2 (en) 2002-07-25
WO2000011001A1 (en) 2000-03-02
DE69903961T2 (de) 2003-07-03
CN1312812A (zh) 2001-09-12
CO5130018A1 (es) 2002-02-27
AU5775899A (en) 2000-03-14
US6555550B1 (en) 2003-04-29
BG105256A (en) 2001-11-30
RU2219179C2 (ru) 2003-12-20

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