IS5902A - Notkun á asýlkarnitínum sem miðlum gegn æxli - Google Patents

Notkun á asýlkarnitínum sem miðlum gegn æxli

Info

Publication number: IS5902A
Authority: IS; Iceland
Prior art keywords: tumor suppressor; acyl carnitine; carnitine; acyl; somatosstatin
Prior art date: 1998-09-30

Application number

IS5902A

Other languages

English (en)

Inventor

Scandurra Laura

Maria Stivala Franca

Allegra Eugenia

Rapisarda Grazia

Original Assignee

Università degli Studi di Catania

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-30

Filing date

2001-03-20

Publication date

2001-03-20

2001-03-20 Application filed by Università degli Studi di Catania filed Critical Università degli Studi di Catania

2001-03-20 Publication of IS5902A publication Critical patent/IS5902A/is

Links

MEFKEPWMEQBLKI-AIRLBKTGSA-O S-adenosyl-L-methionine Chemical compound O[C@@H]1[C@H](O)[C@@H](C[S+](CC[C@H]([NH3+])C([O-])=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 MEFKEPWMEQBLKI-AIRLBKTGSA-O 0.000 title 1
102000001742 Tumor Suppressor Proteins Human genes 0.000 title 1
108010040002 Tumor Suppressor Proteins Proteins 0.000 title 1
RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 abstract 1
229960001009 acetylcarnitine Drugs 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Saccharide Compounds (AREA)

IS5902A 1998-09-30 2001-03-20 Notkun á asýlkarnitínum sem miðlum gegn æxli IS5902A (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT1998MI002090A IT1302289B1 (it)	1998-09-30	1998-09-30	Composizioni farmaceutiche ad attivita' antineoplastica
PCT/EP1999/007170 WO2000018385A2 (en)	1998-09-30	1999-09-27	Use of acylcarnitines as antitumour agents

Publications (1)

Publication Number	Publication Date
IS5902A true IS5902A (is)	2001-03-20

Family

ID=11380776

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5902A IS5902A (is)	1998-09-30	2001-03-20	Notkun á asýlkarnitínum sem miðlum gegn æxli

Country Status (16)

Country	Link
US (1)	US6673839B1 (is)
EP (1)	EP1117393B1 (is)
JP (1)	JP2002525316A (is)
AT (1)	ATE358476T1 (is)
AU (1)	AU761357B2 (is)
CA (1)	CA2345724C (is)
DE (1)	DE69935724T2 (is)
DK (1)	DK1117393T3 (is)
ES (1)	ES2284267T3 (is)
IL (1)	IL142295A (is)
IS (1)	IS5902A (is)
IT (1)	IT1302289B1 (is)
NO (1)	NO20011578L (is)
NZ (1)	NZ510803A (is)
WO (1)	WO2000018385A2 (is)
ZA (1)	ZA200102545B (is)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2006347935A (ja) *	2005-06-15	2006-12-28	Masanori Ogata	炎症性サイトカインの産生が関与する疾患の予防及び／又は治療のための医薬
EA018442B1 (ru) *	2007-03-21	2013-08-30	Сигма-Тау Индустрие Фармасьютике Риуните С.П.А.	Применение l-карнитина для лечения гипертензии, для снижения систолического или пульсового давления крови у субъектов с предиабетом
EA201170732A1 (ru) *	2008-12-01	2011-12-30	Сигма-Тау Индустрие Фармасьютике Риуните С.П.А.	Применение алканоил l-карнитина в комбинации с химиотерапевтическими средствами для лечения новообразований

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH05339148A (ja)	1992-05-28	1993-12-21	T Knight Albert	血液脳関門を通過する物質
US5504069A (en) *	1993-02-11	1996-04-02	Biomeasure, Inc.	Inhibition of trauma-induced tumor growth
IT1277898B1 (it) *	1995-08-03	1997-11-12	Mendes Srl	Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
WO1997006788A1 (en) *	1995-08-14	1997-02-27	Janssen Pharmaceutica N.V.	Transdermal administration of vorozole
JPH11292787A (ja)	1995-08-15	1999-10-26	Asahi Chem Ind Co Ltd	生理活性ペプチドを含有する経粘膜投与製剤
IT1283951B1 (it) *	1996-03-15	1998-05-07	Mendes Srl	Uso della acetil l-carnitina o dei suoi sali farmacologicamente accettabili per il trattamento terapeutico o la profilassi di
DE69923322T2 (de) *	1998-07-30	2005-12-22	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Verwendung von propionyl-l-carnitin und acetyl-l-carnitin zur herstellung von arzneimittel mit antikrebs wirkung

1998
- 1998-09-30 IT IT1998MI002090A patent/IT1302289B1/it active IP Right Grant
1999
- 1999-09-27 JP JP2000571904A patent/JP2002525316A/ja active Pending
- 1999-09-27 AU AU60877/99A patent/AU761357B2/en not_active Ceased
- 1999-09-27 AT AT99947427T patent/ATE358476T1/de not_active IP Right Cessation
- 1999-09-27 WO PCT/EP1999/007170 patent/WO2000018385A2/en not_active Ceased
- 1999-09-27 DE DE69935724T patent/DE69935724T2/de not_active Expired - Lifetime
- 1999-09-27 DK DK99947427T patent/DK1117393T3/da active
- 1999-09-27 NZ NZ510803A patent/NZ510803A/en not_active IP Right Cessation
- 1999-09-27 CA CA002345724A patent/CA2345724C/en not_active Expired - Fee Related
- 1999-09-27 ES ES99947427T patent/ES2284267T3/es not_active Expired - Lifetime
- 1999-09-27 US US09/806,153 patent/US6673839B1/en not_active Expired - Fee Related
- 1999-09-27 IL IL14229599A patent/IL142295A/en not_active IP Right Cessation
- 1999-09-27 EP EP99947427A patent/EP1117393B1/en not_active Expired - Lifetime
2001
- 2001-03-20 IS IS5902A patent/IS5902A/is unknown
- 2001-03-28 ZA ZA200102545A patent/ZA200102545B/en unknown
- 2001-03-28 NO NO20011578A patent/NO20011578L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU761357B2 (en)	2003-06-05
ZA200102545B (en)	2001-09-28
WO2000018385A2 (en)	2000-04-06
JP2002525316A (ja)	2002-08-13
NO20011578L (no)	2001-05-30
IL142295A (en)	2004-08-31
NZ510803A (en)	2003-08-29
IL142295A0 (en)	2002-03-10
WO2000018385A3 (en)	2000-05-25
EP1117393B1 (en)	2007-04-04
ATE358476T1 (de)	2007-04-15
NO20011578D0 (no)	2001-03-28
IT1302289B1 (it)	2000-09-05
CA2345724A1 (en)	2000-04-06
EP1117393A2 (en)	2001-07-25
US6673839B1 (en)	2004-01-06
ITMI982090A1 (it)	2000-03-30
DK1117393T3 (da)	2007-08-06
AU6087799A (en)	2000-04-17
CA2345724C (en)	2009-05-19
ES2284267T3 (es)	2007-11-01
DE69935724T2 (de)	2007-12-27
DE69935724D1 (en)	2007-05-16

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