IS6316A - Aðferð til erfðafræðilegra greininga - Google Patents

Aðferð til erfðafræðilegra greininga

Info

Publication number
IS6316A
IS6316A IS6316A IS6316A IS6316A IS 6316 A IS6316 A IS 6316A IS 6316 A IS6316 A IS 6316A IS 6316 A IS6316 A IS 6316A IS 6316 A IS6316 A IS 6316A
Authority
IS
Iceland
Prior art keywords
genetic analysis
genetic
analysis
Prior art date
Application number
IS6316A
Other languages
English (en)
Inventor
Patil Nila
R. Cox David
J. Berno Anthony
A. Hinds David
P. A. Fodor Stephen
Original Assignee
Perlegen Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perlegen Sciences, Inc. filed Critical Perlegen Sciences, Inc.
Publication of IS6316A publication Critical patent/IS6316A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Artificial Intelligence (AREA)
  • Bioethics (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
  • Public Health (AREA)
  • Software Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Signal Processing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IS6316A 2001-03-30 2002-03-20 Aðferð til erfðafræðilegra greininga IS6316A (is)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28053001P 2001-03-30 2001-03-30
US31326401P 2001-08-17 2001-08-17
US32700601P 2001-10-05 2001-10-05
US33255001P 2001-11-26 2001-11-26

Publications (1)

Publication Number Publication Date
IS6316A true IS6316A (is) 2002-09-30

Family

ID=27501283

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6316A IS6316A (is) 2001-03-30 2002-03-20 Aðferð til erfðafræðilegra greininga

Country Status (11)

Country Link
US (4) US6969589B2 (is)
EP (1) EP1246114B1 (is)
JP (1) JP2003052383A (is)
KR (1) KR20020077283A (is)
CN (1) CN1381591A (is)
AU (1) AU785425B2 (is)
CA (1) CA2380047A1 (is)
IL (2) IL186298A0 (is)
IS (1) IS6316A (is)
MX (1) MXPA02003119A (is)
SG (2) SG119147A1 (is)

Families Citing this family (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7375198B2 (en) * 1993-10-26 2008-05-20 Affymetrix, Inc. Modified nucleic acid probes
AU785425B2 (en) * 2001-03-30 2007-05-17 Genetic Technologies Limited Methods of genomic analysis
WO2003018835A2 (en) * 2001-08-23 2003-03-06 Hvidovre Hospital Method for rapid detection of haplotypes
US6897025B2 (en) * 2002-01-07 2005-05-24 Perlegen Sciences, Inc. Genetic analysis systems and methods
US6977162B2 (en) * 2002-03-01 2005-12-20 Ravgen, Inc. Rapid analysis of variations in a genome
CA2477761A1 (en) * 2002-03-01 2003-09-12 Ravgen, Inc. Methods for detection of genetic disorders
US8725418B2 (en) * 2002-03-25 2014-05-13 Janssen Pharmaceutica, N.V. Data mining of SNP databases for the selection of intragenic SNPs
US20040023275A1 (en) * 2002-04-29 2004-02-05 Perlegen Sciences, Inc. Methods for genomic analysis
US7727720B2 (en) * 2002-05-08 2010-06-01 Ravgen, Inc. Methods for detection of genetic disorders
US7442506B2 (en) * 2002-05-08 2008-10-28 Ravgen, Inc. Methods for detection of genetic disorders
US20070178478A1 (en) * 2002-05-08 2007-08-02 Dhallan Ravinder S Methods for detection of genetic disorders
US9740817B1 (en) 2002-10-18 2017-08-22 Dennis Sunga Fernandez Apparatus for biological sensing and alerting of pharmaco-genomic mutation
CA2512110A1 (en) 2002-12-31 2004-07-22 Mmi Genomics, Inc. Compositions, methods, and systems for inferring bovine breed
US20040146870A1 (en) * 2003-01-27 2004-07-29 Guochun Liao Systems and methods for predicting specific genetic loci that affect phenotypic traits
WO2004081191A2 (en) * 2003-03-12 2004-09-23 Cleveland State University Molecular haplotyping of genomic dna
EP1636730A2 (en) * 2003-06-18 2006-03-22 Applera Corporation Methods and systems for the analysis of biological sequence data
US8346482B2 (en) 2003-08-22 2013-01-01 Fernandez Dennis S Integrated biosensor and simulation system for diagnosis and therapy
WO2005030952A1 (ja) * 2003-09-30 2005-04-07 Riken ハプロタイプの解析方法
US20050266432A1 (en) * 2004-02-26 2005-12-01 Illumina, Inc. Haplotype markers for diagnosing susceptibility to immunological conditions
US20090087854A1 (en) 2007-09-27 2009-04-02 Perlegen Sciences, Inc. Methods for genetic analysis
JP4437050B2 (ja) * 2004-03-26 2010-03-24 株式会社日立製作所 診断支援システム、診断支援方法および診断支援サービスの提供方法
JP4696294B2 (ja) * 2004-08-30 2011-06-08 学校法人慶應義塾 評価方法、ヒト・エストロゲン受容体遺伝子、ゲノムｄｎａ、及び診断マーカー
US20080318214A1 (en) * 2004-09-08 2008-12-25 Genesys Technologies, Inc. Genome Analysis Method
US20060110744A1 (en) 2004-11-23 2006-05-25 Sampas Nicolas M Probe design methods and microarrays for comparative genomic hybridization and location analysis
WO2006077631A1 (ja) * 2005-01-19 2006-07-27 Genesys Technologies, Inc. 関連ゲノム領域（含む関連遺伝子／関連ハプロタイプ）のシステマチック関連遺伝子解析方法
US20060166224A1 (en) * 2005-01-24 2006-07-27 Norviel Vernon A Associations using genotypes and phenotypes
US20060223058A1 (en) * 2005-04-01 2006-10-05 Perlegen Sciences, Inc. In vitro association studies
US20060253262A1 (en) * 2005-04-27 2006-11-09 Emiliem Novel Methods and Devices for Evaluating Poisons
BRPI0612301A2 (pt) * 2005-06-20 2009-01-27 Decode Genetics Ehf mÉtodo para diagnosticar uma suscetibilidade para a diabete tipo ii em um indivÍduo, kit, e, mÉtodo para avaliar um indivÍduo quanto a probabilidade de resposta a um agente terapÊutico de tcf7l2
DK2463387T3 (en) 2005-11-29 2017-01-09 Cambridge Entpr Ltd Markers for breast cancer
CN101365944B (zh) * 2005-12-02 2013-08-07 单倍体技术有限公司 基因作图和确定单倍型的方法
CA2632859C (en) * 2005-12-02 2014-07-15 Simons Haplomics Limited Methods for gene mapping and haplotyping
JP2009523285A (ja) * 2006-01-11 2009-06-18 ネオコデックス・ソシエダッド・リミターダ 遺伝的関連の決定方法および装置
US8080371B2 (en) * 2006-03-01 2011-12-20 The Washington University Markers for addiction
US20110143344A1 (en) * 2006-03-01 2011-06-16 The Washington University Genetic polymorphisms and substance dependence
US10522240B2 (en) 2006-05-03 2019-12-31 Population Bio, Inc. Evaluating genetic disorders
US7702468B2 (en) 2006-05-03 2010-04-20 Population Diagnostics, Inc. Evaluating genetic disorders
US8372584B2 (en) 2006-06-14 2013-02-12 The General Hospital Corporation Rare cell analysis using sample splitting and DNA tags
US20070294113A1 (en) * 2006-06-14 2007-12-20 General Electric Company Method for evaluating correlations between structured and normalized information on genetic variations between humans and their personal clinical patient data from electronic medical patient records
AR063688A1 (es) 2006-08-15 2009-02-11 Monsanto Technology Llc Composiciones y metodos para la produccion de plantas utilizando la informacion de marcador de alta densidad
WO2008050356A1 (en) * 2006-10-27 2008-05-02 Decode Genetics Cancer susceptibility variants on chr8q24.21
EP2137324A2 (en) * 2007-03-26 2009-12-30 Decode Genetics EHF Genetic variants on chr2 and chr16 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment
CN101743326A (zh) * 2007-05-14 2010-06-16 因赛特遗传学公司 筛选核酸中的单核苷酸变异的方法
US20090326832A1 (en) * 2008-06-27 2009-12-31 Microsoft Corporation Graphical models for the analysis of genome-wide associations
DK2438193T3 (en) 2009-06-01 2015-10-19 Genetic Technologies Ltd Methods for assessing the risk of breast cancer
US8965076B2 (en) 2010-01-13 2015-02-24 Illumina, Inc. Data processing system and methods
WO2011094731A2 (en) 2010-02-01 2011-08-04 The Board Of Trustees Of The Leland Stanford Junior University Methods for diagnosis and treatment of non-insulin dependent diabetes mellitus
DK2556171T3 (en) 2010-04-05 2015-12-14 Prognosys Biosciences Inc Spatially CODED BIOLOGICAL ASSAYS
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
WO2012018387A2 (en) 2010-08-02 2012-02-09 Population Diagnotics, Inc. Compositions and methods for discovery of causative mutations in genetic disorders
CN102206701B (zh) * 2010-09-19 2015-01-21 深圳华大基因科技有限公司 遗传性疾病相关基因的鉴定方法
CN110838348A (zh) * 2010-11-01 2020-02-25 皇家飞利浦电子股份有限公司 包括专有测试的特许使用费的自动化代理的体外诊断测试
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
WO2013054200A2 (en) 2011-10-10 2013-04-18 The Hospital For Sick Children Methods and compositions for screening and treating developmental disorders
US8990250B1 (en) 2011-10-11 2015-03-24 23Andme, Inc. Cohort selection with privacy protection
EP2773779B1 (en) 2011-11-04 2020-10-14 Population Bio, Inc. Methods and compositions for diagnosing, prognosing, and treating neurological conditions
CN104094266A (zh) * 2011-11-07 2014-10-08 独创系统公司 用于识别原因性基因组变体的方法和系统
DK2812452T3 (da) 2012-02-09 2020-06-29 Population Bio Inc Fremgangsmåder og sammensætninger til screening og behandling af udviklingsforstyrrelser
EP2865764B1 (en) 2012-06-20 2018-09-05 Toray Industries, Inc. Method for detecting nucleic acid and use of a nucleic acid detection kit
EP2895621B1 (en) 2012-09-14 2020-10-21 Population Bio, Inc. Methods and compositions for diagnosing, prognosing, and treating neurological conditions
US10233495B2 (en) 2012-09-27 2019-03-19 The Hospital For Sick Children Methods and compositions for screening and treating developmental disorders
WO2014060483A1 (en) 2012-10-17 2014-04-24 Spatial Transcriptomics Ab Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
KR101538692B1 (ko) * 2012-12-18 2015-07-27 연세대학교 산학협력단 지놈 변이 또는 후생학적 변이를 분석하기 위한 컴퓨터 실행 방법
WO2014098479A1 (ko) * 2012-12-18 2014-06-26 연세대학교 산학협력단 지놈 변이 또는 후생학적 변이를 분석하기 위한 컴퓨터 실행 방법
WO2014113204A1 (en) 2013-01-17 2014-07-24 Personalis, Inc. Methods and systems for genetic analysis
US20140249761A1 (en) * 2013-03-01 2014-09-04 DNANEXUS, Inc. Characterizing uncharacterized genetic mutations
US10322227B2 (en) * 2013-03-15 2019-06-18 410 Medical, Inc. Apparatus, kits and related methods for fluid infusion
US9868979B2 (en) 2013-06-25 2018-01-16 Prognosys Biosciences, Inc. Spatially encoded biological assays using a microfluidic device
JP2015035212A (ja) * 2013-07-29 2015-02-19 アジレント・テクノロジーズ・インクＡｇｉｌｅｎｔ Ｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． ターゲットシークエンシングパネルから変異を見つける方法
WO2015031689A1 (en) 2013-08-30 2015-03-05 Personalis, Inc. Methods and systems for genomic analysis
WO2015042708A1 (en) 2013-09-25 2015-04-02 Bio-Id Diagnostic Inc. Methods for detecting nucleic acid fragments
GB2535066A (en) 2013-10-03 2016-08-10 Personalis Inc Methods for analyzing genotypes
DK3511422T3 (da) 2013-11-12 2023-02-06 Population Bio Inc Fremgangsmåder og sammensætninger til diagnosticering, prognose og behandling af endometriose
GB2558326B (en) 2014-09-05 2021-01-20 Population Bio Inc Methods and compositions for inhibiting and treating neurological conditions
AU2015327756B2 (en) 2014-09-30 2018-01-04 Genetic Technologies Limited Methods for assessing risk of developing breast cancer
WO2016070131A1 (en) 2014-10-30 2016-05-06 Personalis, Inc. Methods for using mosaicism in nucleic acids sampled distal to their origin
US10424396B2 (en) * 2015-03-27 2019-09-24 Sentieon Inc. Computation pipeline of location-dependent variant calls
EP4282977B1 (en) 2015-04-10 2024-06-05 10x Genomics Sweden AB Spatially distinguished, multiplex nucleic acid analysis of biological specimens
US10395759B2 (en) 2015-05-18 2019-08-27 Regeneron Pharmaceuticals, Inc. Methods and systems for copy number variant detection
CN105354444B (zh) * 2015-11-24 2018-06-19 华南理工大学 基于易感snp筛查复杂疾病易感snp组合的方法
CA3012783A1 (en) 2016-01-28 2017-08-03 The University Of Melbourne Methods for assessing risk of developing colorectal cancer
US12071669B2 (en) 2016-02-12 2024-08-27 Regeneron Pharmaceuticals, Inc. Methods and systems for detection of abnormal karyotypes
US11299783B2 (en) 2016-05-27 2022-04-12 Personalis, Inc. Methods and systems for genetic analysis
US11725232B2 (en) 2016-10-31 2023-08-15 The Hong Kong University Of Science And Technology Compositions, methods and kits for detection of genetic variants for alzheimer's disease
MY203439A (en) * 2016-12-22 2024-06-28 Illumina Inc Array including sequencing primer and non-sequencing entity
CA3047888C (en) * 2016-12-23 2025-05-27 Oxford BioDynamics PLC Method for typing epigenetic chromosome interactions
US10240205B2 (en) 2017-02-03 2019-03-26 Population Bio, Inc. Methods for assessing risk of developing a viral disease using a genetic test
US10176296B2 (en) 2017-05-17 2019-01-08 International Business Machines Corporation Algebraic phasing of polyploids
WO2018226941A1 (en) * 2017-06-08 2018-12-13 Nantomics, Llc An integrative panomic approach to pharmacogenomics screening
CN108681658B (zh) * 2018-05-22 2021-09-21 贵州医科大学 一种优化外源基因在大肠杆菌中翻译速度的方法
US10801064B2 (en) 2018-05-31 2020-10-13 Personalis, Inc. Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
US11814750B2 (en) 2018-05-31 2023-11-14 Personalis, Inc. Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
EP4177356B1 (en) 2018-08-08 2024-05-08 PML Screening, LLC Methods for assessing risk of developing a viral disease using a genetic test
CN109979530B (zh) * 2019-03-26 2021-03-16 北京市商汤科技开发有限公司 一种基因变异识别方法、装置和存储介质
WO2020243579A1 (en) 2019-05-30 2020-12-03 10X Genomics, Inc. Methods of detecting spatial heterogeneity of a biological sample
EP4055610A4 (en) 2019-11-05 2023-11-29 Personalis, Inc. ESTIMATION OF TUMOR PURITY FROM SINGLE SAMPLES
EP4158054B1 (en) 2020-06-02 2025-04-16 10X Genomics, Inc. Spatial transcriptomics for antigen-receptors
EP4025692A2 (en) 2020-06-02 2022-07-13 10X Genomics, Inc. Nucleic acid library methods
EP4421186B1 (en) 2020-06-08 2025-08-13 10X Genomics, Inc. Methods of determining a surgical margin and methods of use thereof
EP3982367A1 (en) * 2020-10-09 2022-04-13 KWS SAAT SE & Co. KGaA Haplotype-block-based imputation of genomic markers
US12071667B2 (en) 2020-11-04 2024-08-27 10X Genomics, Inc. Sequence analysis using meta-stable nucleic acid molecules
US12060603B2 (en) 2021-01-19 2024-08-13 10X Genomics, Inc. Methods for internally controlled in situ assays using padlock probes
WO2022256422A1 (en) 2021-06-02 2022-12-08 10X Genomics, Inc. Sample analysis using asymmetric circularizable probes
EP4413580A4 (en) 2021-10-05 2025-08-13 Personalis Inc PERSONALIZED TESTS FOR PERSONALIZED CANCER MONITORING
CN114649055B (zh) * 2022-04-15 2022-10-21 北京贝瑞和康生物技术有限公司 用于检测单核苷酸变异和插入缺失的方法、设备和介质
CN115035948B (zh) * 2022-07-20 2023-01-24 北京阅微基因技术股份有限公司 一种str引物的设计方法和系统
CN115376610A (zh) * 2022-09-01 2022-11-22 新疆碳智干细胞库有限公司 一种snp变异率的批量组间对比分析方法
DE102023105888A1 (de) * 2023-03-09 2024-09-12 KWS SAAT SE & Co. KGaA Verfahren zur Identifizierung eines Kandidaten, nämlich eines Genlocus und/oder einer Sequenzvariante, der für mindestens ein (phänotypisches) Merkmal indikativ ist
EP4705515A1 (en) 2023-05-03 2026-03-11 10X Genomics, Inc. Methods and compositions for spatial assay
WO2025240662A1 (en) * 2024-05-15 2025-11-20 Foresite Labs, Llc Pharmacomimetic variant and prs interactions for body mass index
CN119312114B (zh) * 2024-12-16 2025-03-25 湘江实验室 一种干细胞低氧扩增阶段的异常预测方法及相关设备
CN120005846B (zh) * 2024-12-30 2025-10-31 江南大学 提高udp糖基转移酶催化活性的改造方法及改造所得突变体

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965188A (en) * 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4800159A (en) * 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US5527681A (en) * 1989-06-07 1996-06-18 Affymax Technologies N.V. Immobilized molecular synthesis of systematically substituted compounds
US5744101A (en) * 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5800992A (en) * 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5424186A (en) * 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
AU8517391A (en) 1990-09-12 1992-03-30 Scientific Generics Limited Electrochemical denaturation of double-stranded nucleic acid
ES2155822T3 (es) 1990-12-06 2001-06-01 Affymetrix Inc Compuestos y su utilizacion en una estrategia de sintesis binaria.
DE69233087T2 (de) * 1991-11-22 2003-12-24 Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) Verfahren zur Herstellung von Polymerarrays
US5412087A (en) * 1992-04-24 1995-05-02 Affymax Technologies N.V. Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces
US5384261A (en) * 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
US5861242A (en) * 1993-06-25 1999-01-19 Affymetrix, Inc. Array of nucleic acid probes on biological chips for diagnosis of HIV and methods of using the same
US20020048749A1 (en) 1998-04-15 2002-04-25 Robert J. Lipshutz Methods for polymorphism identifcation and profiling
US5837832A (en) * 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
WO1995011995A1 (en) 1993-10-26 1995-05-04 Affymax Technologies N.V. Arrays of nucleic acid probes on biological chips
US6027880A (en) * 1995-08-02 2000-02-22 Affymetrix, Inc. Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis
AU7623194A (en) 1993-09-03 1995-03-22 Vpi Holdings Ltd. Oligonucleotides with rna cleavage activity
US5578832A (en) * 1994-09-02 1996-11-26 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
EP0746614A1 (en) 1994-02-23 1996-12-11 Ribozyme Pharmaceuticals, Inc. Method and reagent for inhibiting the expression of disease related genes
US5512462A (en) * 1994-02-25 1996-04-30 Hoffmann-La Roche Inc. Methods and reagents for the polymerase chain reaction amplification of long DNA sequences
US5837810A (en) 1994-03-15 1998-11-17 The Scripps Research Institute Polypeptides of lipopolysaccharide binding protein
ATE175723T1 (de) 1994-03-15 1999-01-15 Scient Generics Ltd Elektrochemische denatusierung von doppelsträngiger nukleinsäure
US5571639A (en) * 1994-05-24 1996-11-05 Affymax Technologies N.V. Computer-aided engineering system for design of sequence arrays and lithographic masks
US5459325A (en) * 1994-07-19 1995-10-17 Molecular Dynamics, Inc. High-speed fluorescence scanner
US5795716A (en) 1994-10-21 1998-08-18 Chee; Mark S. Computer-aided visualization and analysis system for sequence evaluation
US5599695A (en) * 1995-02-27 1997-02-04 Affymetrix, Inc. Printing molecular library arrays using deprotection agents solely in the vapor phase
FI954922A7 (fi) 1995-10-16 1997-04-17 Picopak Oy Valmistusmenetelmä sekä kontaktinystyrakenne puolijohdepalojen tiheitä pintaliitoksia varten
US5871697A (en) * 1995-10-24 1999-02-16 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US6300063B1 (en) * 1995-11-29 2001-10-09 Affymetrix, Inc. Polymorphism detection
US5972614A (en) * 1995-12-06 1999-10-26 Genaissance Pharmaceuticals Genome anthologies for harvesting gene variants
JP2002515738A (ja) 1996-01-23 2002-05-28 アフィメトリックス，インコーポレイティド 核酸分析法
US6228575B1 (en) * 1996-02-08 2001-05-08 Affymetrix, Inc. Chip-based species identification and phenotypic characterization of microorganisms
US5981956A (en) * 1996-05-16 1999-11-09 Affymetrix, Inc. Systems and methods for detection of labeled materials
US6150094A (en) * 1996-05-23 2000-11-21 Qiagen Gmbh Use of an osmolyte for reducing or abolishing no-covalent interactions of biological molecules to inert surfaces
US6007231A (en) * 1996-08-14 1999-12-28 Academy Of Applied Science Method of computer aided automated diagnostic DNA test design, and apparatus therefor
US5953727A (en) * 1996-10-10 1999-09-14 Incyte Pharmaceuticals, Inc. Project-based full-length biomolecular sequence database
US6143496A (en) * 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
US6368799B1 (en) 1997-06-13 2002-04-09 Affymetrix, Inc. Method to detect gene polymorphisms and monitor allelic expression employing a probe array
EP1007739A2 (en) 1997-09-05 2000-06-14 Sidney Kimmel Cancer Center Selection of pcr primer pairs to amplify a group of nucleotide sequences
US6262838B1 (en) * 1998-03-20 2001-07-17 Genetic Microsystems Inc Focusing in microscope systems
AU768721B2 (en) 1998-04-15 2004-01-08 Genset S.A. Genomic sequence of the 5-lipoxygenase-activating protein (FLAP), polymorphic markers thereof and methods for detection of asthma
CA2348609A1 (en) * 1998-11-10 2000-05-18 Genset S.A. Methods, software and apparati for identifying genomic regions harboring a gene associated with a detectable trait
WO2001001218A2 (en) 1999-06-25 2001-01-04 Genaissance Pharmaceuticals, Inc. Methods for obtaining and using haplotype data
WO2001004270A1 (en) 1999-07-13 2001-01-18 Genaissance Pharmaceuticals, Inc. Drug target isogenes: polymorphisms in the interleukin 4 receptor alpha gene
AU2001231091A1 (en) 2000-01-21 2001-07-31 Vincent P. Stanton Jr. Identification of genetic components of drug response
AU2001253720A1 (en) 2000-04-18 2001-10-30 Genaissance Pharmaceuticals, Inc. Method and system for determining haplotypes from a collection of polymorphisms
US6214557B1 (en) * 2000-06-06 2001-04-10 Washington University Cold sensitive mutant DNA polymerases
US6931326B1 (en) * 2000-06-26 2005-08-16 Genaissance Pharmaceuticals, Inc. Methods for obtaining and using haplotype data
US6521747B2 (en) * 2000-08-28 2003-02-18 Genaissance Pharmaceuticals, Inc. Haplotypes of the AGTR1 gene
US20020098498A1 (en) 2000-09-29 2002-07-25 Bader Joel S. Method of identifying genetic regions associated with disease and predicting responsiveness to therapeutic agents
DE10062566A1 (de) 2000-12-15 2002-06-20 Genprofile Ag Verfahren und Vorrichtung zur Ermittlung von Primer-Sequenzen
AU785425B2 (en) 2001-03-30 2007-05-17 Genetic Technologies Limited Methods of genomic analysis
AU2002324649A1 (en) 2001-08-04 2003-02-24 General Hospital Corporation Haplotype map of the human genome and uses therefor
US6898531B2 (en) * 2001-09-05 2005-05-24 Perlegen Sciences, Inc. Algorithms for selection of primer pairs
US6740510B2 (en) 2001-09-05 2004-05-25 Perlegen Sciences, Inc. Methods for amplification of nucleic acids
US20040023237A1 (en) 2001-11-26 2004-02-05 Perelegen Sciences Inc. Methods for genomic analysis
US6897025B2 (en) * 2002-01-07 2005-05-24 Perlegen Sciences, Inc. Genetic analysis systems and methods
US20040146870A1 (en) 2003-01-27 2004-07-29 Guochun Liao Systems and methods for predicting specific genetic loci that affect phenotypic traits

Also Published As

Publication number Publication date
AU785425B2 (en) 2007-05-17
EP1246114A3 (en) 2004-07-21
US20160371429A1 (en) 2016-12-22
CN1381591A (zh) 2002-11-27
US20030099964A1 (en) 2003-05-29
AU785425C (en) 2002-10-03
US11031098B2 (en) 2021-06-08
AU2746002A (en) 2002-10-03
SG119147A1 (en) 2006-02-28
MXPA02003119A (es) 2003-05-27
IL186298A0 (en) 2008-01-20
US6969589B2 (en) 2005-11-29
EP1246114B1 (en) 2019-05-29
US20110020815A1 (en) 2011-01-27
EP1246114A2 (en) 2002-10-02
SG142154A1 (en) 2008-05-28
IL148783A (en) 2008-04-13
CA2380047A1 (en) 2002-09-30
US20050272086A1 (en) 2005-12-08
KR20020077283A (ko) 2002-10-11
IL148783A0 (en) 2002-09-12
JP2003052383A (ja) 2003-02-25

Similar Documents

Publication Publication Date Title
IS6316A (is) Aðferð til erfðafræðilegra greininga
FI20010977L (fi) Kromatografinen erotusmenetelmä
BRPI0313238A2 (pt) método
DE50204020D1 (de) Mikrotom
FI20011568L (fi) Liikennevirran analysointimenetelmä
FI20012271L (fi) Menetelmä vastinpisteiden määrittämiseksi
ATE502118T1 (de) Amplifizierungsverfahren
DE60213940D1 (de) Proben-Einführungssystem
DK1456404T3 (da) Fremgangsmåde til at bestemme difibrotids biologiske aktivitet
DE60212776D1 (de) Spezifisches Bindungsanalyseverfahren
AU2002364749A8 (en) Method for protein expression analysis
NO20043985L (no) Fremgangsmate for rekombinering av genetiske elementer
IS7288A (is) Aðferðir til að hreinsa levófloxasín
DK1392722T3 (da) Fremgangsmåde vedrörende echinocandiner
EP1696230A4 (en) PROTEIN ANALYSIS PROCESS
DE50200752D1 (de) Mikrotom
NO20023358D0 (no) Metode
FI20010221A0 (fi) Menetelmä entsyymin uuttamiseksi
EE00305U1 (et) Praimerekstensioonil põhinev geenianalüüsi meetod
IS6928A (is) Aðferðir til að framleiða mirtasapínmilliefni
SE0104471D0 (sv) New method
GB0104993D0 (en) Methods for analysis of RNA
FI20000326L (fi) Analyysimenetelmä
FI20031050L (fi) Menetelmä proteiinien katkaisuun
ITBO20010469A0 (it) Metodo per il condizionamento di sigari