IS7019A - Crystalline form of 'R- (R , R ) - 2- (4-fluorophenyl) -beta, delta-dihydroxy-5- (1-methylethyl) -3-phenyl-4-phenylamino) carbonyl] -1H-carboxylic acid pyrrole-1-heptanoic acid calcium salt (2: 1) (atorvastatin) - Google Patents

Crystalline form of 'R- (R *, R *) - 2- (4-fluorophenyl) -beta, delta-dihydroxy-5- (1-methylethyl) -3-phenyl-4-phenylamino) carbonyl] -1H-carboxylic acid pyrrole-1-heptanoic acid calcium salt (2: 1) (atorvastatin)

Info

Publication number: IS7019A
Authority: IS; Iceland
Prior art keywords: atorvastatin; phenylamino; methylethyl; fluorophenyl; dihydroxy
Prior art date: 2002-05-21

Application number

IS7019A

Other languages

Icelandic (is)

Inventor

Robert Byrn Stephen

Andrew Coates David

Sue Gushurst Karen

Grant Morrison Ii Henry

Park Aeri

Ivanova Vlahova Petinka

Jane Li Zheng

Francis Krzyzaniak Joseph

Original Assignee

Warner-Lambert Company Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-21

Filing date

2003-11-10

Publication date

2003-11-10

2002-05-21 Priority claimed from PCT/IB2002/001796 external-priority patent/WO2003004470A1/en

2003-11-10 Application filed by Warner-Lambert Company Llc filed Critical Warner-Lambert Company Llc

2003-11-10 Publication of IS7019A publication Critical patent/IS7019A/en

Links

125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 title 1
XUKUURHRXDUEBC-KAYWLYCHSA-N Atorvastatin Chemical compound C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-KAYWLYCHSA-N 0.000 title 1
XUKUURHRXDUEBC-UHFFFAOYSA-N Atorvastatin Natural products C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CCC(O)CC(O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-UHFFFAOYSA-N 0.000 title 1
229960005370 atorvastatin Drugs 0.000 title 1
WPPHUTKYAGKEJJ-UHFFFAOYSA-L calcium;7-pyrrol-1-ylheptanoate Chemical compound [Ca+2].[O-]C(=O)CCCCCCN1C=CC=C1.[O-]C(=O)CCCCCCN1C=CC=C1 WPPHUTKYAGKEJJ-UHFFFAOYSA-L 0.000 title 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 title 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 title 1

IS7019A 2002-05-21 2003-11-10 Crystalline form of 'R- (R *, R *) - 2- (4-fluorophenyl) -beta, delta-dihydroxy-5- (1-methylethyl) -3-phenyl-4-phenylamino) carbonyl] -1H-carboxylic acid pyrrole-1-heptanoic acid calcium salt (2: 1) (atorvastatin) IS7019A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/IB2002/001796 WO2003004470A1 (en)	2001-06-29	2002-05-21	Crystalline forms of 'r-(r,r)!-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-'phenylamino)carbonyl!-1h-pyrrole-1-heptanoic acid calcium salt (2:1) (atorvastatin)

Publications (1)

Publication Number	Publication Date
IS7019A true IS7019A (en)	2003-11-10

Family

ID=36700993

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS7019A IS7019A (en)	2002-05-21	2003-11-10	Crystalline form of 'R- (R , R ) - 2- (4-fluorophenyl) -beta, delta-dihydroxy-5- (1-methylethyl) -3-phenyl-4-phenylamino) carbonyl] -1H-carboxylic acid pyrrole-1-heptanoic acid calcium salt (2: 1) (atorvastatin)

Country Status (1)

Country	Link
IS (1)	IS7019A (en)

2003
- 2003-11-10 IS IS7019A patent/IS7019A/en unknown

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IS7019A - Crystalline form of 'R- (R *, R *) - 2- (4-fluorophenyl) -beta, delta-dihydroxy-5- (1-methylethyl) -3-phenyl-4-phenylamino) carbonyl] -1H-carboxylic acid pyrrole-1-heptanoic acid calcium salt (2: 1) (atorvastatin) - Google Patents