IS7260A - Nýmyndun og hreinsun valasýklóvírs - Google Patents

Nýmyndun og hreinsun valasýklóvírs

Info

Publication number
IS7260A
IS7260A IS7260A IS7260A IS7260A IS 7260 A IS7260 A IS 7260A IS 7260 A IS7260 A IS 7260A IS 7260 A IS7260 A IS 7260A IS 7260 A IS7260 A IS 7260A
Authority
IS
Iceland
Prior art keywords
valacyclovir
purification
synthesis
Prior art date
Application number
IS7260A
Other languages
English (en)
Inventor
Yu Etinger Marina
M. Yudovich Lev
Yuzefovich Michael
A. Nisnevich Gennady
Zion Dolitzky Ben
Pertsikov Boris
Tishin Boris
Blasberger Dina
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of IS7260A publication Critical patent/IS7260A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
IS7260A 2001-11-14 2004-05-11 Nýmyndun og hreinsun valasýklóvírs IS7260A (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33280201P 2001-11-14 2001-11-14
US34227301P 2001-12-21 2001-12-21
PCT/US2002/036269 WO2003041647A2 (en) 2001-11-14 2002-11-13 Synthesis and purification of valacyclovir

Publications (1)

Publication Number Publication Date
IS7260A true IS7260A (is) 2004-05-11

Family

ID=26988392

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7260A IS7260A (is) 2001-11-14 2004-05-11 Nýmyndun og hreinsun valasýklóvírs

Country Status (14)

Country Link
US (2) US6849737B2 (is)
EP (1) EP1465894A4 (is)
JP (1) JP2005508993A (is)
KR (2) KR20070020149A (is)
CN (1) CN1307177C (is)
CA (2) CA2649826A1 (is)
HR (1) HRP20040511A2 (is)
IL (1) IL161969A0 (is)
IN (1) IN2007DE04250A (is)
IS (1) IS7260A (is)
MX (1) MX242714B (is)
NO (1) NO20042433L (is)
PL (1) PL371732A1 (is)
WO (1) WO2003041647A2 (is)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1436295A4 (en) * 2001-09-07 2007-07-11 Teva Pharma CRISTALLINE FORMS OF VALACYCLOVIR HYDROCHLORIDE
AU2002348022B2 (en) * 2001-11-05 2006-06-15 Glaxo Group Limited Anhydrous crystal form of valaciclovir hydrochloride
CA2649826A1 (en) * 2001-11-14 2003-05-22 Teva Pharmaceutical Industries Ltd. Synthesis and purification of valacyclovir
US20050043329A1 (en) * 2002-09-06 2005-02-24 Shlomit Wizel Crystalline forms of valacyclovir hydrochloride
ATE335743T1 (de) * 2002-10-16 2006-09-15 Teva Pharma Verfahren zur verminderung von restalkoholen im kristallinen valacyclovir-hydrochlorid
US20050059684A1 (en) * 2002-10-16 2005-03-17 Ben-Zion Dolitzky Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
CA2548608A1 (en) * 2002-12-09 2004-06-24 Texcontor Etablissement Anhydrous crystalline form of valacyclovir hydrochloride
US7786302B2 (en) * 2003-05-30 2010-08-31 Eczacibasi-Zentiva Kimyasal Urunler Sanayi Ve Ticaret A.S. Crystalline forms of valacyclovir hydrochloride
EP1638972A2 (en) * 2003-06-02 2006-03-29 Teva Pharmaceutical Industries Limited Novel crystalline forms of valacyclovir hydrochloride
MXPA06008197A (es) * 2004-01-21 2007-04-02 Teva Pharma Proceso para la preparacion de clorhidrato de valaciclovir.
EP1761535A1 (en) * 2004-06-30 2007-03-14 Teva Pharmaceutical Industries Ltd Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
CN101068814A (zh) 2004-09-04 2007-11-07 特瓦制药工业有限公司 分离的伐昔洛韦杂质，制备伐昔洛韦杂质的方法及其作为参比标准物的应用
US7958087B2 (en) * 2004-11-17 2011-06-07 Iron Mountain Incorporated Systems and methods for cross-system digital asset tag propagation
EP1746098A1 (en) * 2005-07-21 2007-01-24 SOLMAG S.p.A. Valacyclovir polymorphs and a process for the preparation thereof
US20070112193A1 (en) * 2005-11-14 2007-05-17 Khunt Mayur D Valacyclovir process
GB0605344D0 (en) * 2006-03-17 2006-04-26 Pliva Istrazivanje I Razvoj D Pharmaceutically acceptable salts and polymorphic forms
CN1903854B (zh) * 2006-08-09 2012-05-23 丽珠医药集团股份有限公司 一种合成盐酸伐昔洛韦的方法
JP5152180B2 (ja) * 2007-04-27 2013-02-27 味の素株式会社 バラシクロビルの製造方法
US20080281099A1 (en) * 2007-05-07 2008-11-13 Mayur Devjibhai Khunt Process for purifying valacyclovir hydrochloride and intermediates thereof
CN102584825B (zh) * 2011-01-17 2014-04-02 四川科伦药物研究有限公司 一种合成盐酸伐昔洛韦的方法
US10836765B2 (en) * 2016-03-03 2020-11-17 Aurobindo Pharma Ltd Process for the preparation of valacyclovir
CN106632335A (zh) * 2016-12-27 2017-05-10 河南康达制药有限公司 一种盐酸伐昔洛韦的制备方法
CN114621227B (zh) * 2022-02-28 2024-07-09 海南久常制药有限公司 一种盐酸伐昔洛韦、制剂及其制备方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
GB8719367D0 (en) 1987-08-15 1987-09-23 Wellcome Found Therapeutic compounds
ES2157259T3 (es) * 1993-06-10 2001-08-16 Rolabo Sl Procedimiento para preparar esteres de aminoacidos y analogos de nucleosidos.
GB9501178D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Guanine derivative
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
US6117453A (en) * 1995-04-14 2000-09-12 Pharma Pass Solid compositions containing polyethylene oxide and an active ingredient
US5672243A (en) * 1995-11-28 1997-09-30 Mosel Vitelic, Inc. Antireflection coating for highly reflective photolithographic layers comprising chromium oxide or chromium suboxide
ATE254463T1 (de) * 1996-01-19 2003-12-15 Glaxo Group Ltd Verwendung von valaciclovir zur herstellung eines arzneimittels zur behandlung von genitalherpes durch einmal tägliche verabreichung
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US6040446A (en) * 1996-01-26 2000-03-21 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
IT1283447B1 (it) * 1996-07-18 1998-04-21 Ind Chimica Srl Processo di preparazione del valaciclovir e relativi intermedi
AU735438B2 (en) * 1996-11-12 2001-07-05 Medivir Ab Nucleosides
EP1436295A4 (en) * 2001-09-07 2007-07-11 Teva Pharma CRISTALLINE FORMS OF VALACYCLOVIR HYDROCHLORIDE
AU2002348022B2 (en) * 2001-11-05 2006-06-15 Glaxo Group Limited Anhydrous crystal form of valaciclovir hydrochloride
CA2649826A1 (en) * 2001-11-14 2003-05-22 Teva Pharmaceutical Industries Ltd. Synthesis and purification of valacyclovir
US20060147519A1 (en) * 2002-06-24 2006-07-06 Ashish Gogia Process for the preparation of robust formulations of valacyclovir hydrochloride tablets
US20050043329A1 (en) * 2002-09-06 2005-02-24 Shlomit Wizel Crystalline forms of valacyclovir hydrochloride
ATE335743T1 (de) * 2002-10-16 2006-09-15 Teva Pharma Verfahren zur verminderung von restalkoholen im kristallinen valacyclovir-hydrochlorid
US20050059684A1 (en) * 2002-10-16 2005-03-17 Ben-Zion Dolitzky Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
CA2548608A1 (en) * 2002-12-09 2004-06-24 Texcontor Etablissement Anhydrous crystalline form of valacyclovir hydrochloride
US7786302B2 (en) * 2003-05-30 2010-08-31 Eczacibasi-Zentiva Kimyasal Urunler Sanayi Ve Ticaret A.S. Crystalline forms of valacyclovir hydrochloride
EP1638972A2 (en) * 2003-06-02 2006-03-29 Teva Pharmaceutical Industries Limited Novel crystalline forms of valacyclovir hydrochloride
MXPA06008197A (es) * 2004-01-21 2007-04-02 Teva Pharma Proceso para la preparacion de clorhidrato de valaciclovir.
US20060178512A1 (en) * 2005-02-04 2006-08-10 Cheruthur Govindan Method for preparing amino acid esters of nucleoside analogues
EP1746098A1 (en) * 2005-07-21 2007-01-24 SOLMAG S.p.A. Valacyclovir polymorphs and a process for the preparation thereof
US20070112193A1 (en) * 2005-11-14 2007-05-17 Khunt Mayur D Valacyclovir process
US20080281099A1 (en) * 2007-05-07 2008-11-13 Mayur Devjibhai Khunt Process for purifying valacyclovir hydrochloride and intermediates thereof

Also Published As

Publication number Publication date
NO20042433L (no) 2004-07-22
US20050130993A1 (en) 2005-06-16
HRP20040511A2 (en) 2004-10-31
WO2003041647A3 (en) 2003-11-20
EP1465894A2 (en) 2004-10-13
IL161969A0 (en) 2005-11-20
EP1465894A4 (en) 2008-10-08
CA2649826A1 (en) 2003-05-22
KR20070020149A (ko) 2007-02-16
MX242714B (es) 2006-12-15
CA2465928C (en) 2010-01-19
IN2007DE04250A (is) 2007-08-31
US20030153757A1 (en) 2003-08-14
PL371732A1 (en) 2005-06-27
CN1307177C (zh) 2007-03-28
CN1612878A (zh) 2005-05-04
WO2003041647A2 (en) 2003-05-22
MXPA04004656A (es) 2004-08-13
CA2465928A1 (en) 2003-05-22
US6849737B2 (en) 2005-02-01
KR20050044449A (ko) 2005-05-12
JP2005508993A (ja) 2005-04-07

Similar Documents

Publication Publication Date Title
NO20042433L (no) Syntese og rensing av valasyklovir
IS7344A (is) Stýrð efnasmíði síprasídóns og samsetninga af því
NO20041975L (no) Bicyklisk oksopyridin og oksopyrimidinderivater
NO20041582L (no) Antistoffinhibitorer av GDF-8 og anvendelse derav
DE60101968D1 (de) Kristallform alpha des perindopril-tert-butylaminsalzes
DK1404809T3 (da) Forbedrede hudsubstitutter og anvendelser deraf
DK1417175T3 (da) Substituerede dihydro-3-halo-1h-pyrazol-5-carboxylater og fremstillingog anvendelse heraf
NO20041272L (no) Tetracycline derivatives and methods of use thereof
NO20033854L (no) N-but-3-enyl-norbuprenorfin og fremgangsmåter for anvendelse
NO20041449L (no) Krystallinformer av valasyklovir-hydroklorid
DK2305689T3 (da) Syntese af naturligt forekommende ecteinascidiner og relateredeforbindelser
FI20010558L (fi) Kappaleiden paikannus
IS7128A (is) Hreinsun á zaleploni og kristölluð form þess
NO20041968L (no) Anvendelse av cystationin
NO20021569D0 (no) Rensete kitiner og fremgangsmåte for deres fremstilling
IS6884A (is) Aðferðir við að nýta líffræðilegan fjölbreytileika
AR028070A1 (es) Sintesis de compuestos de ciclohexendimetanol o ciclohexandimetanol
NO20034172L (no) Bisykliske guanidinderivater og terapeutiske anvendelser derav
NO20042126L (no) Syntese av 2-aralkoksyadenosiner og 2-alkoksyadenosiner
PT1392670E (pt) Derivados substituidos de c-furan-2-il-metilamina e c-tiofen-2-il-metilamina
DE60233658D1 (de) Konkatenation von Sprachsignalen
NO20033743L (no) Fremgangsmåte og fremstilling citalopram
EP1497355A4 (en) Synthesis and applicatons of polymaleimide
ATE328506T1 (de) Schmuckstück
ITBA20010029U1 (it) Gioiello di puglia