IS8072A - Miðlar úr bak kólesteról flutningi í meðferð á kólesterólhækkun - Google Patents

Miðlar úr bak kólesteról flutningi í meðferð á kólesterólhækkun

Info

Publication number: IS8072A
Authority: IS; Iceland
Prior art keywords: hypercholesterolemia; treatment; transfer agents; cholesterol transfer; cholesterol
Prior art date: 2003-04-22

Application number

IS8072A

Other languages

English (en)

Inventor

C. Sircar Jagadish

Alisala Kashinatham

Nikoulin Igor

Original Assignee

Avanir Pharmaceuticals

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-04-22

Filing date

2005-10-13

Publication date

2005-10-13

2005-10-13 Application filed by Avanir Pharmaceuticals filed Critical Avanir Pharmaceuticals

2005-10-13 Publication of IS8072A publication Critical patent/IS8072A/is

Links

HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title 2
208000035150 Hypercholesterolemia Diseases 0.000 title 1
235000012000 cholesterol Nutrition 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Zoology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Epidemiology (AREA)
Obesity (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Investigating Or Analysing Biological Materials (AREA)

IS8072A 2003-04-22 2005-10-13 Miðlar úr bak kólesteról flutningi í meðferð á kólesterólhækkun IS8072A (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US46466703P	2003-04-22	2003-04-22
PCT/US2004/012445 WO2004094471A2 (en)	2003-04-22	2004-04-22	Mediators of reverse cholesterol transport for the treatment of hypercholesterolemia

Publications (1)

Publication Number	Publication Date
IS8072A true IS8072A (is)	2005-10-13

Family

ID=33310929

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS8072A IS8072A (is)	2003-04-22	2005-10-13	Miðlar úr bak kólesteról flutningi í meðferð á kólesterólhækkun

Country Status (18)

Country	Link
US (1)	US20060166891A1 (is)
EP (1)	EP1615954A2 (is)
JP (1)	JP2007534612A (is)
KR (1)	KR20050114283A (is)
CN (1)	CN1809590A (is)
AR (1)	AR044058A1 (is)
AU (1)	AU2004233333A1 (is)
BR (1)	BRPI0409609A (is)
CA (1)	CA2522758A1 (is)
CL (1)	CL2004000858A1 (is)
IS (1)	IS8072A (is)
MX (1)	MXJL05000046A (is)
NO (1)	NO20055474L (is)
PE (1)	PE20050136A1 (is)
RU (1)	RU2005135139A (is)
TW (1)	TW200503747A (is)
UY (1)	UY28282A1 (is)
WO (1)	WO2004094471A2 (is)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060009487A1 (en) *	2004-06-09	2006-01-12	Sircar Jagadish C	Heterocyclic derivatives for treatment of hyperlipidemia and related diseases
TW200603794A (en) *	2004-06-09	2006-02-01	Avanir Pharmaceuticals	Small molecules for treatment of hypercholesterolemia and related diseases
EP1753782A1 (en) *	2004-06-09	2007-02-21	Avanir Pharmaceuticals	Mediators of reverse cholesterol transport for the treatment of hypercholesterolemia
WO2006049597A1 (en) *	2004-10-27	2006-05-11	Avanir Pharmaceuticals	Amino acid-derived compounds as modulators of the reverse cholesterol transport
WO2007055873A2 (en) *	2005-11-04	2007-05-18	Avanir Pharmaceuticals	Process for the manufacture of peptide facilitators of reverse cholesterol transport
US20080096900A1 (en)	2006-06-26	2008-04-24	Amgen Inc.	Methods for treating atherosclerosis
EP2234493A4 (en) *	2007-12-21	2011-05-25	Univ Cincinnati	THERAPEUTIC USE OF CARBOXYLESTERLIPASE INHIBITORS
GB0918579D0 (en) *	2009-10-22	2009-12-09	Imp Innovations Ltd	Gadd45beta targeting agents
WO2011079214A1 (en) *	2009-12-23	2011-06-30	Artery Therapeutics, Inc.,	Diagnosis and treatment of reverse cholesterol transport deficiency-related diseases
US20110288017A1 (en) *	2010-03-01	2011-11-24	Leslie Frost	Apo-lipoprotein propeptide
US11840707B2 (en)	2016-05-31	2023-12-12	Institut De Cardiologie De Montreal	Co-culture system and method for in vitro assessment of reverse cholesterol transport
MX2021008661A (es)	2019-01-18	2021-08-19	Astrazeneca Ab	Inhibidores de la pcsk9 y metodos de uso de los mismos.
BR112021013807A2 (pt)	2019-01-18	2021-11-30	Astrazeneca Ab	Inibidores de pcsk9 e seus métodos de uso
CN113929737B (zh) *	2021-10-20	2024-07-23	中国科学院香港创新研究院再生医学与健康创新中心	一种多肽及其作为cck受体激动剂/拮抗剂的应用
WO2025024564A1 (en) *	2023-07-24	2025-01-30	The Board Of Regents Of The University Of Texas System	Small molecules that prevent statin-induced accumulation of hmg coa reductase

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE437153B (sv) *	1976-12-01	1985-02-11	Kabi Ab	Specifika kromogena enzymsubstrat for serinproteaser
US4448715A (en) *	1981-11-02	1984-05-15	University Of Miami	Tagged pyroglu-L-Phe-L-Arg derivatives, substrates and assays for kallikrein
US4643988A (en) *	1984-05-15	1987-02-17	Research Corporation	Amphipathic peptides
DE3781263T2 (de) *	1986-12-15	1993-04-08	Inst Nat Sante Rech Med	Peptid-derivate und deren verwendung in der therapie.
US4952562A (en) *	1989-09-29	1990-08-28	Rorer Pharmaceutical Corporation	Anti-thrombotic peptides and pseudopeptides
WO1999003880A1 (en) *	1997-07-15	1999-01-28	Novo Nordisk A/S	Nociceptin analogues
US6037323A (en) *	1997-09-29	2000-03-14	Jean-Louis Dasseux	Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6821774B1 (en) *	1999-06-18	2004-11-23	Cv Therapeutics, Inc.	Compositions and methods for increasing cholesterol efflux and raising HDL using ATP binding cassette transporter ABC1
US6664230B1 (en) *	2000-08-24	2003-12-16	The Regents Of The University Of California	Orally administered peptides to ameliorate atherosclerosis
BR0115257A (pt) *	2000-11-10	2003-08-12	Proteopharma Aps	Análogos de apolipoproteìna
EP1383922A4 (en) *	2001-04-10	2005-03-30	Agensys Inc	NUCLEIC ACID AND ASSOCIATED PROTEIN SUITABLE FOR THE TREATMENT AND DETECTION OF CANCER WITH THE LABEL 158P3D2

2004
- 2004-04-22 TW TW093111209A patent/TW200503747A/zh unknown
- 2004-04-22 AR ARP040101362A patent/AR044058A1/es not_active Application Discontinuation
- 2004-04-22 UY UY28282A patent/UY28282A1/es not_active Application Discontinuation
- 2004-04-22 WO PCT/US2004/012445 patent/WO2004094471A2/en not_active Ceased
- 2004-04-22 RU RU2005135139/13A patent/RU2005135139A/ru not_active Application Discontinuation
- 2004-04-22 KR KR1020057020078A patent/KR20050114283A/ko not_active Withdrawn
- 2004-04-22 JP JP2006513224A patent/JP2007534612A/ja active Pending
- 2004-04-22 CL CL200400858A patent/CL2004000858A1/es unknown
- 2004-04-22 US US10/829,855 patent/US20060166891A1/en not_active Abandoned
- 2004-04-22 AU AU2004233333A patent/AU2004233333A1/en not_active Abandoned
- 2004-04-22 CN CNA2004800174775A patent/CN1809590A/zh active Pending
- 2004-04-22 EP EP04760126A patent/EP1615954A2/en not_active Ceased
- 2004-04-22 CA CA002522758A patent/CA2522758A1/en not_active Abandoned
- 2004-04-22 BR BRPI0409609-6A patent/BRPI0409609A/pt not_active IP Right Cessation
- 2004-04-22 PE PE2004000400A patent/PE20050136A1/es not_active Application Discontinuation
- 2004-04-22 MX MXJL05000046A patent/MXJL05000046A/es not_active Application Discontinuation
2005
- 2005-10-13 IS IS8072A patent/IS8072A/is unknown
- 2005-11-18 NO NO20055474A patent/NO20055474L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2004094471A2 (en)	2004-11-04
JP2007534612A (ja)	2007-11-29
US20060166891A1 (en)	2006-07-27
TW200503747A (en)	2005-02-01
CN1809590A (zh)	2006-07-26
WO2004094471A3 (en)	2005-06-16
BRPI0409609A (pt)	2006-04-18
NO20055474D0 (no)	2005-11-18
KR20050114283A (ko)	2005-12-05
PE20050136A1 (es)	2005-04-20
RU2005135139A (ru)	2007-05-27
CL2004000858A1 (es)	2005-04-22
CA2522758A1 (en)	2004-11-04
UY28282A1 (es)	2004-11-30
AR044058A1 (es)	2005-08-24
AU2004233333A1 (en)	2004-11-04
EP1615954A2 (en)	2006-01-18
NO20055474L (no)	2006-01-23
MXJL05000046A (es)	2005-12-22

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DK1553950T3 (da)	2007-10-15	Terapeutisk behandling
DE50303099D1 (de)	2006-06-01	Patientenlagerungstisch
NO20050689L (no)	2005-03-21	Terapeutisk anvendelse
ATE442835T1 (de)	2009-10-15	Oberflächenbehandlung
SE0301854L (sv)	2003-08-26	Antiigensättningsbehandling
EP1512745A4 (en)	2006-05-17	PIGMENT PROTEIN
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