IS8072A - Miðlar úr bak kólesteról flutningi í meðferð á kólesterólhækkun - Google Patents

Miðlar úr bak kólesteról flutningi í meðferð á kólesterólhækkun

Info

Publication number: IS8072A
Authority: IS; Iceland
Prior art keywords: hypercholesterolemia; treatment; transfer agents; cholesterol transfer; cholesterol
Prior art date: 2003-04-22

Application number

IS8072A

Other languages

English (en)

Inventor

C. Sircar Jagadish

Alisala Kashinatham

Nikoulin Igor

Original Assignee

Avanir Pharmaceuticals

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-04-22

Filing date

2005-10-13

Publication date

2005-10-13

2005-10-13 Application filed by Avanir Pharmaceuticals filed Critical Avanir Pharmaceuticals

2005-10-13 Publication of IS8072A publication Critical patent/IS8072A/is

Links

HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title 2
208000035150 Hypercholesterolemia Diseases 0.000 title 1
235000012000 cholesterol Nutrition 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Hematology (AREA)
Immunology (AREA)
Obesity (AREA)
Cardiology (AREA)
Diabetes (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Investigating Or Analysing Biological Materials (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

IS8072A 2003-04-22 2005-10-13 Miðlar úr bak kólesteról flutningi í meðferð á kólesterólhækkun IS8072A (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US46466703P	2003-04-22	2003-04-22
PCT/US2004/012445 WO2004094471A2 (en)	2003-04-22	2004-04-22	Mediators of reverse cholesterol transport for the treatment of hypercholesterolemia

Publications (1)

Publication Number	Publication Date
IS8072A true IS8072A (is)	2005-10-13

Family

ID=33310929

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS8072A IS8072A (is)	2003-04-22	2005-10-13	Miðlar úr bak kólesteról flutningi í meðferð á kólesterólhækkun

Country Status (18)

Country	Link
US (1)	US20060166891A1 (is)
EP (1)	EP1615954A2 (is)
JP (1)	JP2007534612A (is)
KR (1)	KR20050114283A (is)
CN (1)	CN1809590A (is)
AR (1)	AR044058A1 (is)
AU (1)	AU2004233333A1 (is)
BR (1)	BRPI0409609A (is)
CA (1)	CA2522758A1 (is)
CL (1)	CL2004000858A1 (is)
IS (1)	IS8072A (is)
MX (1)	MXJL05000046A (is)
NO (1)	NO20055474L (is)
PE (1)	PE20050136A1 (is)
RU (1)	RU2005135139A (is)
TW (1)	TW200503747A (is)
UY (1)	UY28282A1 (is)
WO (1)	WO2004094471A2 (is)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1968928A (zh) *	2004-06-09	2007-05-23	阿文尼尔药品公司	用于治疗高脂血症及相关疾病的杂环衍生物
KR20070029198A (ko) *	2004-06-09	2007-03-13	아바니르 파마슈티컬스	고콜레스테롤혈증의 치료를 위한 역 콜레스테롤 수송의매개제
KR20070043711A (ko) *	2004-06-09	2007-04-25	아바니르 파마슈티컬스	고콜레스테롤혈증과 관련 질환의 치료를 위한 소분자
WO2006049597A1 (en) *	2004-10-27	2006-05-11	Avanir Pharmaceuticals	Amino acid-derived compounds as modulators of the reverse cholesterol transport
WO2007055873A2 (en) *	2005-11-04	2007-05-18	Avanir Pharmaceuticals	Process for the manufacture of peptide facilitators of reverse cholesterol transport
ES2376396T3 (es)	2006-06-26	2012-03-13	Amgen Inc.	Método para tratar aterosclerosis.
EP2234493A4 (en) *	2007-12-21	2011-05-25	Univ Cincinnati	THERAPEUTIC USE OF CARBOXYLESTERLIPASE INHIBITORS
GB0918579D0 (en) *	2009-10-22	2009-12-09	Imp Innovations Ltd	Gadd45beta targeting agents
EP2517013A4 (en) *	2009-12-23	2013-07-17	Artery Therapeutics Inc	DIAGNOSIS AND TREATMENT OF DISEASES ASSOCIATED WITH DEFICIENT REVERSE CHOLESTER INTRANSPORT
US20110288017A1 (en) *	2010-03-01	2011-11-24	Leslie Frost	Apo-lipoprotein propeptide
EP3464613A4 (en) *	2016-05-31	2020-01-08	Institut de Cardiologie de Montréal	CO-CULTURE SYSTEM AND METHOD FOR IN-VITRO EVALUATION OF CHOLESTERIN RETURN
RS66416B1 (sr)	2019-01-18	2025-02-28	Astrazeneca Ab	6'-[[(1s,3s)-3-[[5-(difluorometoksi)-2-pirimidinil]amino]ciklopentil]amino][1(2h),3'-bipiridin]-2-on kao inhibitor pcsk9 i metode njegove primene
EP3911640A4 (en)	2019-01-18	2022-10-26	Astrazeneca AB	PCSK9 INHIBITORS AND METHODS OF USE THEREOF
WO2025024564A1 (en) *	2023-07-24	2025-01-30	The Board Of Regents Of The University Of Texas System	Small molecules that prevent statin-induced accumulation of hmg coa reductase

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE437153B (sv) *	1976-12-01	1985-02-11	Kabi Ab	Specifika kromogena enzymsubstrat for serinproteaser
US4448715A (en) *	1981-11-02	1984-05-15	University Of Miami	Tagged pyroglu-L-Phe-L-Arg derivatives, substrates and assays for kallikrein
US4643988A (en) *	1984-05-15	1987-02-17	Research Corporation	Amphipathic peptides
ES2052595T3 (es) *	1986-12-15	1994-07-16	Inst Nat Sante Rech Med	Nuevos derivados peptidicos y su aplicacion en especial en terapeutica.
US4952562A (en) *	1989-09-29	1990-08-28	Rorer Pharmaceutical Corporation	Anti-thrombotic peptides and pseudopeptides
AU8334298A (en) *	1997-07-15	1999-02-10	Novo Nordisk A/S	Nociceptin analogues
US6037323A (en) *	1997-09-29	2000-03-14	Jean-Louis Dasseux	Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6821774B1 (en) *	1999-06-18	2004-11-23	Cv Therapeutics, Inc.	Compositions and methods for increasing cholesterol efflux and raising HDL using ATP binding cassette transporter ABC1
US6664230B1 (en) *	2000-08-24	2003-12-16	The Regents Of The University Of California	Orally administered peptides to ameliorate atherosclerosis
AU2002213843B2 (en) *	2000-11-10	2008-02-07	F. Hoffmann-La Roche Ltd.	Apolipoprotein analogues
US20040003418A1 (en) *	2001-04-10	2004-01-01	Aya Jakobovits	Nucleic acid and corresponding protein entitled 158P3D2 useful in treatment and detection of cancer

2004
- 2004-04-22 MX MXJL05000046A patent/MXJL05000046A/es not_active Application Discontinuation
- 2004-04-22 TW TW093111209A patent/TW200503747A/zh unknown
- 2004-04-22 RU RU2005135139/13A patent/RU2005135139A/ru not_active Application Discontinuation
- 2004-04-22 AU AU2004233333A patent/AU2004233333A1/en not_active Abandoned
- 2004-04-22 JP JP2006513224A patent/JP2007534612A/ja active Pending
- 2004-04-22 CL CL200400858A patent/CL2004000858A1/es unknown
- 2004-04-22 WO PCT/US2004/012445 patent/WO2004094471A2/en not_active Ceased
- 2004-04-22 EP EP04760126A patent/EP1615954A2/en not_active Ceased
- 2004-04-22 BR BRPI0409609-6A patent/BRPI0409609A/pt not_active IP Right Cessation
- 2004-04-22 PE PE2004000400A patent/PE20050136A1/es not_active Application Discontinuation
- 2004-04-22 CA CA002522758A patent/CA2522758A1/en not_active Abandoned
- 2004-04-22 UY UY28282A patent/UY28282A1/es not_active Application Discontinuation
- 2004-04-22 US US10/829,855 patent/US20060166891A1/en not_active Abandoned
- 2004-04-22 AR ARP040101362A patent/AR044058A1/es not_active Application Discontinuation
- 2004-04-22 CN CNA2004800174775A patent/CN1809590A/zh active Pending
- 2004-04-22 KR KR1020057020078A patent/KR20050114283A/ko not_active Withdrawn
2005
- 2005-10-13 IS IS8072A patent/IS8072A/is unknown
- 2005-11-18 NO NO20055474A patent/NO20055474L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
RU2005135139A (ru)	2007-05-27
BRPI0409609A (pt)	2006-04-18
NO20055474L (no)	2006-01-23
UY28282A1 (es)	2004-11-30
AR044058A1 (es)	2005-08-24
WO2004094471A2 (en)	2004-11-04
PE20050136A1 (es)	2005-04-20
CL2004000858A1 (es)	2005-04-22
WO2004094471A3 (en)	2005-06-16
KR20050114283A (ko)	2005-12-05
MXJL05000046A (es)	2005-12-22
US20060166891A1 (en)	2006-07-27
EP1615954A2 (en)	2006-01-18
JP2007534612A (ja)	2007-11-29
NO20055474D0 (no)	2005-11-18
TW200503747A (en)	2005-02-01
CA2522758A1 (en)	2004-11-04
AU2004233333A1 (en)	2004-11-04
CN1809590A (zh)	2006-07-26

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NO20050689L (no)	2005-03-21	Terapeutisk anvendelse
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