IS8200A - Efnasmíðað gen sem táknar mótefnisvaka mennsks húðþekjuvaxtarþáttar 2/NEU og notkun á því - Google Patents

Efnasmíðað gen sem táknar mótefnisvaka mennsks húðþekjuvaxtarþáttar 2/NEU og notkun á því

Info

Publication number
IS8200A
IS8200A IS8200A IS8200A IS8200A IS 8200 A IS8200 A IS 8200A IS 8200 A IS8200 A IS 8200A IS 8200 A IS8200 A IS 8200A IS 8200 A IS8200 A IS 8200A
Authority
IS
Iceland
Prior art keywords
neu
antigen
growth factor
epidermal growth
synthetic gene
Prior art date
Application number
IS8200A
Other languages
English (en)
Inventor
Gallo Pasquale
Monaci Paolo
Nuzzo Maurizio
Original Assignee
Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa filed Critical Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa
Publication of IS8200A publication Critical patent/IS8200A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IS8200A 2003-07-21 2005-12-27 Efnasmíðað gen sem táknar mótefnisvaka mennsks húðþekjuvaxtarþáttar 2/NEU og notkun á því IS8200A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48923703P 2003-07-21 2003-07-21
PCT/EP2004/008234 WO2005012527A1 (en) 2003-07-21 2004-07-20 Synthetic gene encoding human epidermal growth factor 2/neu antigen and uses thereof

Publications (1)

Publication Number Publication Date
IS8200A true IS8200A (is) 2005-12-27

Family

ID=34115329

Family Applications (1)

Application Number Title Priority Date Filing Date
IS8200A IS8200A (is) 2003-07-21 2005-12-27 Efnasmíðað gen sem táknar mótefnisvaka mennsks húðþekjuvaxtarþáttar 2/NEU og notkun á því

Country Status (14)

Country Link
US (2) US20070111957A1 (is)
EP (1) EP1649020B1 (is)
JP (1) JP4772674B2 (is)
KR (1) KR101141507B1 (is)
CN (2) CN100558894C (is)
AU (1) AU2004261724B2 (is)
CA (1) CA2532460C (is)
IL (1) IL173208A (is)
IS (1) IS8200A (is)
NO (1) NO20060813L (is)
NZ (1) NZ544543A (is)
RU (1) RU2397249C2 (is)
WO (1) WO2005012527A1 (is)
ZA (1) ZA200600248B (is)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009006479A2 (en) * 2007-07-02 2009-01-08 Etubics Corporation Methods and compositions for producing an adenovirus vector for use with multiple vaccinations
GB2484058A (en) * 2009-12-01 2012-04-04 Uni Konstanz Prostate cancer DNA vaccine
US9605276B2 (en) 2012-08-24 2017-03-28 Etubics Corporation Replication defective adenovirus vector in vaccination
CN103555765B (zh) * 2013-05-30 2015-01-07 中南大学湘雅医院 一种转录调控肿瘤靶向复制溶瘤腺病毒载体、携带治疗基因腺病毒及其制备方法和应用
AU2015243849B2 (en) 2014-04-10 2020-12-17 Seattle Children's Hospital (dba Seattle Children's Research Institute) Transgene genetic tags and methods of use
KR20170102002A (ko) 2015-01-09 2017-09-06 이투빅스 코포레이션 에볼라 바이러스 백신접종을 위한 방법 및 조성물
AU2016205215B2 (en) 2015-01-09 2021-03-11 Etubics Corporation Methods and compositions for combination immunotherapy
US11149087B2 (en) 2015-04-20 2021-10-19 Etubics Corporation Methods and compositions for combination immunotherapy
JP7162530B2 (ja) 2015-08-07 2022-10-28 シアトル チルドレンズ ホスピタル (ディービーエイ シアトル チルドレンズ リサーチ インスティテュート) 固形腫瘍を標的とする二重特異性car t細胞
US11266726B2 (en) 2015-10-30 2022-03-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions and methods for the treatment of HER2-expressing solid tumors
US11408005B2 (en) 2016-12-12 2022-08-09 Seattle Children's Hospital Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells
JP7202362B2 (ja) 2017-08-24 2023-01-11 バヴァリアン・ノルディック・アクティーゼルスカブ 組み換えmva及び抗体の静脈内投与を用いた、がん治療のための併用療法
CN112941132B (zh) * 2021-05-17 2021-07-23 烟台市华昕生物医药科技有限公司 一种利用大肠杆菌表达寡肽-1的方法
CN115925875A (zh) * 2021-08-20 2023-04-07 百奥赛图(北京)医药科技股份有限公司 Her2基因人源化非人动物及其构建方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
US5869445A (en) * 1993-03-17 1999-02-09 University Of Washington Methods for eliciting or enhancing reactivity to HER-2/neu protein
US5837523A (en) * 1994-05-05 1998-11-17 The Trustees Of The University Of Pennsylvania Compositions and methods of treating tumors
IT1276662B1 (it) * 1995-04-04 1997-11-03 Uni Degli Studi Camerino Vaccini polinucleotidici
US5922845A (en) * 1996-07-11 1999-07-13 Medarex, Inc. Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
ZA988461B (en) * 1997-09-18 1999-03-30 Idec Pharma Corp Synergistic composition and methods for treating neoplastic or cancerous growths and for restoring or boosting hematopoiesis
AU780109B2 (en) * 1999-01-29 2005-03-03 Corixa Corporation HER-2/neu fusion proteins
PL365789A1 (pl) * 2000-08-14 2005-01-10 Corixa Corporation Kompozycje oraz sposoby leczenia i diagnozowania nowotworów związanych z Her-2/neu
AU2001294562B2 (en) 2000-09-15 2007-05-24 Merck & Co., Inc. Enhanced First Generation Adenovirus Vaccines Expressing Codon Optimized HIV1-Gag, Pol, Nef and Modifications
CN1164330C (zh) * 2001-07-19 2004-09-01 中国医学科学院基础医学研究所 一种重组复制缺陷型腺病毒载体狂犬病毒基因工程疫苗
KR100555211B1 (ko) * 2002-07-16 2006-03-03 주식회사 팬제노믹스 항암효과를 갖는 Her-2/neu DNA 백신
WO2004041065A2 (en) * 2002-10-30 2004-05-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services METHODS FOR PROPHYLAXIS AND TREATMENT OF HER-2/neu TUMORS
EP1583833A1 (en) 2003-01-03 2005-10-12 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Rhesus her2/neu, nucleotides encoding same, and uses thereof

Also Published As

Publication number Publication date
EP1649020A1 (en) 2006-04-26
WO2005012527A9 (en) 2006-03-02
ZA200600248B (en) 2007-03-28
AU2004261724A1 (en) 2005-02-10
CN1826409A (zh) 2006-08-30
RU2006105195A (ru) 2006-06-27
KR101141507B1 (ko) 2012-05-08
IL173208A (en) 2014-06-30
EP1649020B1 (en) 2017-01-11
US20070111957A1 (en) 2007-05-17
AU2004261724B2 (en) 2010-06-17
CN100558894C (zh) 2009-11-11
CN101173282A (zh) 2008-05-07
US7662586B2 (en) 2010-02-16
RU2397249C2 (ru) 2010-08-20
US20090098604A1 (en) 2009-04-16
JP4772674B2 (ja) 2011-09-14
WO2005012527A1 (en) 2005-02-10
CA2532460A1 (en) 2005-02-10
CN101173282B (zh) 2011-04-06
KR20060052852A (ko) 2006-05-19
NO20060813L (no) 2006-03-20
JP2006527989A (ja) 2006-12-14
NZ544543A (en) 2009-03-31
CA2532460C (en) 2012-04-24
IL173208A0 (en) 2006-06-11

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