IS8223A - Naphthalene derivatives that inhibit cytochrome P-450 - Google Patents

Naphthalene derivatives that inhibit cytochrome P-450

Info

Publication number
IS8223A
IS8223A IS8223A IS8223A IS8223A IS 8223 A IS8223 A IS 8223A IS 8223 A IS8223 A IS 8223A IS 8223 A IS8223 A IS 8223A IS 8223 A IS8223 A IS 8223A
Authority
IS
Iceland
Prior art keywords
naphthalene derivatives
inhibit cytochrome
cytochrome
inhibit
naphthalene
Prior art date
Application number
IS8223A
Other languages
Icelandic (is)
Inventor
Smith Vanessa
Nigro Anthony
Mulvihill Mark
Cesario Cara
Anne Beck Patricia
Lucas Castelhano Arlindo
Original Assignee
Osi Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osi Pharmaceuticals, Inc. filed Critical Osi Pharmaceuticals, Inc.
Publication of IS8223A publication Critical patent/IS8223A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
IS8223A 2003-07-10 2006-01-10 Naphthalene derivatives that inhibit cytochrome P-450 IS8223A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48638203P 2003-07-10 2003-07-10
PCT/US2004/022282 WO2005007631A1 (en) 2003-07-10 2004-07-12 Naphthylene derivatives as cytochrome p450 inhibitors

Publications (1)

Publication Number Publication Date
IS8223A true IS8223A (en) 2006-01-10

Family

ID=34079229

Family Applications (1)

Application Number Title Priority Date Filing Date
IS8223A IS8223A (en) 2003-07-10 2006-01-10 Naphthalene derivatives that inhibit cytochrome P-450

Country Status (15)

Country Link
EP (1) EP1654236A1 (en)
JP (1) JP4832295B2 (en)
KR (1) KR20060052799A (en)
CN (1) CN1819996B (en)
AU (1) AU2004257257B2 (en)
BR (1) BRPI0412424A (en)
CA (1) CA2532078A1 (en)
IL (1) IL172812A0 (en)
IS (1) IS8223A (en)
MX (1) MXPA06000401A (en)
NO (1) NO20060114L (en)
RU (1) RU2363696C2 (en)
SG (1) SG144941A1 (en)
UA (1) UA87822C2 (en)
WO (1) WO2005007631A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2550010A1 (en) 2003-12-17 2005-06-30 Allergan, Inc. Methods for treating retinoid responsive disorders using selective inhibitors of cyp26a and cyp26b
US7662844B2 (en) 2004-07-12 2010-02-16 Osi Pharmaceuticals, Inc. Naphthylene derivatives as cytochrome P450 inhibitors
EP2576544A4 (en) * 2010-06-01 2013-09-11 Angion Biomedica Corp CYTOCHROM P450 HEMMER AND USES THEREOF
US10414760B2 (en) 2016-11-29 2019-09-17 Angion Biomedica Corp. Cytochrome P450 inhibitors and uses thereof
KR20180039185A (en) * 2010-11-13 2018-04-17 이노크린 파마슈티컬즈, 인크. Metalloenzyme inhibitor compounds
EA201390876A1 (en) * 2010-12-13 2013-12-30 Вайамет Фармасьютикалс, Инк. METALLIC ENZYME INHIBITING COMPOUNDS
CN102586187A (en) * 2012-02-23 2012-07-18 深圳市中美康士生物科技有限公司 In vitro preservation method and culture medium for neutrophils
WO2014015137A2 (en) * 2012-07-18 2014-01-23 Angion Biomedica Corp. Compositions and methods for treating dysproliferative diseases
EP3180335B1 (en) 2014-08-11 2021-05-05 Angion Biomedica Corporation Cytochrome p450 inhibitors and uses thereof
CN104523967B (en) * 2014-12-12 2017-08-01 扬子江药业集团北京海燕药业有限公司 A kind of Bai Ai capsules as CYP enzyme inhibitors application
CN107531631B (en) 2014-12-31 2021-09-03 安吉昂生物医药公司 Methods and agents for treating diseases
GB201602572D0 (en) * 2016-02-12 2016-03-30 Eriksson Leif And Strid Ake And Sirsjö Allan New compound and uses
WO2018065288A1 (en) 2016-10-07 2018-04-12 Bayer Cropscience Aktiengesellschaft 2-[2-phenyl-1-(sulfonyl-methyl)-vinyl]-imidazo-[4,5-b] pyridine derivatives and related compounds as pesticides in plant protection
UY37556A (en) 2017-01-10 2018-07-31 Bayer Ag HETEROCYCLIC DERIVATIVES AS PESTICIDES
AU2018208422B2 (en) 2017-01-10 2021-11-11 Bayer Aktiengesellschaft Heterocyclene derivatives as pest control agents
WO2024223797A1 (en) 2023-04-28 2024-10-31 Institut National de la Santé et de la Recherche Médicale Use of cyp3a4 inhibitors for the treatment of hepatitis d virus (hdv) infections
CN116903531B (en) * 2023-07-21 2025-12-12 上海中医药大学 Inhibitors of cytochrome P450 enzyme 3A4, their preparation methods and applications

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL291944A (en) * 1960-05-04
NL131915C (en) * 1966-07-27
DE3508903A1 (en) * 1985-03-13 1986-09-18 Hoechst Ag, 6230 Frankfurt NEW 3-PYRIDYLMETHYLNAPHTYL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
DE3628545A1 (en) * 1985-09-23 1987-04-23 Hoechst Ag ARYLMETHYLAZOLES AND THEIR SALTS, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING THEM AND THEIR USE
AU5285593A (en) * 1992-10-21 1994-05-09 Sankyo Company Limited Azole compound
US6268363B1 (en) * 1997-11-28 2001-07-31 Lg Chemical Ltd. Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof
ATE293102T1 (en) * 1998-04-23 2005-04-15 Takeda Pharmaceutical NAPHTHALENE DERIVATIVES, THEIR PRODUCTION AND USE
JP4546589B2 (en) * 1998-04-23 2010-09-15 武田薬品工業株式会社 Naphthalene derivatives
FR2796070B1 (en) * 1999-07-06 2003-02-21 Lipha BENZODIAZEPINES DERIVATIVES FOR USE IN THE TREATMENT OF DYSLIPIDEMIA, ATHEROSCLEROSIS AND DIABETES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND METHODS OF PREPARATION
PE20010781A1 (en) * 1999-10-22 2001-08-08 Takeda Chemical Industries Ltd COMPOUNDS 1- (1H-IMIDAZOL-4-IL) -1- (NAFTIL-2-SUBSTITUTED) ETHANOL, ITS PRODUCTION AND USE
JP4520012B2 (en) * 1999-10-22 2010-08-04 武田薬品工業株式会社 1-Substituted-1- (1H-imidazol-4-yl) methanols

Also Published As

Publication number Publication date
UA87822C2 (en) 2009-08-25
AU2004257257B2 (en) 2011-05-12
JP2007523866A (en) 2007-08-23
JP4832295B2 (en) 2011-12-07
EP1654236A1 (en) 2006-05-10
AU2004257257A1 (en) 2005-01-27
RU2363696C2 (en) 2009-08-10
MXPA06000401A (en) 2006-03-17
NO20060114L (en) 2006-02-09
WO2005007631A1 (en) 2005-01-27
SG144941A1 (en) 2008-08-28
CN1819996A (en) 2006-08-16
CA2532078A1 (en) 2005-01-27
RU2006103996A (en) 2006-07-10
KR20060052799A (en) 2006-05-19
BRPI0412424A (en) 2006-09-05
IL172812A0 (en) 2006-06-11
CN1819996B (en) 2010-10-27

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