IS8234A - Kalíum- eða natríumsalt (-)-2-{[2-(4-hýdroxýfenýl)etýl]þíó}-3-[4-(2-{4-[(metýlsúlfónýl)oxý]fenoxý}fenýl]própansýru og notkun þeirra í læknisfræði - Google Patents

Kalíum- eða natríumsalt (-)-2-{[2-(4-hýdroxýfenýl)etýl]þíó}-3-[4-(2-{4-[(metýlsúlfónýl)oxý]fenoxý}fenýl]própansýru og notkun þeirra í læknisfræði

Info

Publication number: IS8234A
Authority: IS; Iceland
Prior art keywords: methylsulfonyl; thio; hydroxyphenyl; phenoxy; oxy
Prior art date: 2003-06-18

Application number

IS8234A

Other languages

English (en)

Inventor

Ahlqvist Matti

Hans Bohlin Martin

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-18

Filing date

2006-01-16

Publication date

2006-01-16

2006-01-16 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2006-01-16 Publication of IS8234A publication Critical patent/IS8234A/is

Links

125000004203 4-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 title 1
XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 title 1
125000004170 methylsulfonyl group Chemical group [H]C([H])([H])S(*)(=O)=O 0.000 title 1
DUWWHGPELOTTOE-UHFFFAOYSA-N n-(5-chloro-2,4-dimethoxyphenyl)-3-oxobutanamide Chemical compound COC1=CC(OC)=C(NC(=O)CC(C)=O)C=C1Cl DUWWHGPELOTTOE-UHFFFAOYSA-N 0.000 title 1
125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 title 1
229910052700 potassium Inorganic materials 0.000 title 1
239000011591 potassium Substances 0.000 title 1
235000019260 propionic acid Nutrition 0.000 title 1
159000000000 sodium salts Chemical class 0.000 title 1
125000000446 sulfanediyl group Chemical group *S* 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/06—Potassium compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/04—Sodium compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Diabetes (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Child & Adolescent Psychology (AREA)
Emergency Medicine (AREA)
Psychology (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Psychiatry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IS8234A 2003-06-18 2006-01-16 Kalíum- eða natríumsalt (-)-2-{[2-(4-hýdroxýfenýl)etýl]þíó}-3-[4-(2-{4-[(metýlsúlfónýl)oxý]fenoxý}fenýl]própansýru og notkun þeirra í læknisfræði IS8234A (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0314131.4A GB0314131D0 (en)	2003-06-18	2003-06-18	Therapeutic agents
PCT/GB2004/002595 WO2004113284A1 (en)	2003-06-18	2004-06-16	Potassium or sodium salt of (-)-2-{`2-(4-hydroxyphenyl)ethyl!-thio-3-`4-(2-{4-`(methzlsulfonzl) oxy !phenoxy}phenyl!propanoic acid and their use in medicine

Publications (1)

Publication Number	Publication Date
IS8234A true IS8234A (is)	2006-01-16

Family

ID=27636790

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS8234A IS8234A (is)	2003-06-18	2006-01-16	Kalíum- eða natríumsalt (-)-2-{[2-(4-hýdroxýfenýl)etýl]þíó}-3-[4-(2-{4-[(metýlsúlfónýl)oxý]fenoxý}fenýl]própansýru og notkun þeirra í læknisfræði

Country Status (20)

Country	Link
US (1)	US20070099997A1 (is)
EP (1)	EP1641749A1 (is)
JP (1)	JP2006527750A (is)
KR (1)	KR20060026427A (is)
CN (1)	CN1835920A (is)
AR (1)	AR044800A1 (is)
AU (1)	AU2004249485A1 (is)
BR (1)	BRPI0411515A (is)
CA (1)	CA2529251A1 (is)
CO (1)	CO5650240A2 (is)
GB (1)	GB0314131D0 (is)
IL (1)	IL172440A0 (is)
IS (1)	IS8234A (is)
MX (1)	MXPA05013826A (is)
NO (1)	NO20055927L (is)
RU (1)	RU2005141068A (is)
TW (1)	TW200503679A (is)
UY (1)	UY28367A1 (is)
WO (1)	WO2004113284A1 (is)
ZA (1)	ZA200510196B (is)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE0104333D0 (sv)	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
EP1517883B8 (en)	2002-06-20	2008-05-21	AstraZeneca AB	Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance
GB0314075D0 (en) *	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0427524D0 (en)	2004-12-16	2005-01-19	Astrazeneca Ab	Chemical process

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5089514A (en) *	1990-06-14	1992-02-18	Pfizer Inc.	3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
US5232945A (en) *	1992-07-20	1993-08-03	Pfizer Inc.	3-aryl-2-hydroxypropionic acid derivatives and analogs as antihypertensives
MA26634A1 (fr) *	1998-06-04	2004-12-20	Astra Ab	Nouveaux derives de l'acide 3-aryl propionique et analogues
SE9801992D0 (sv) *	1998-06-04	1998-06-04	Astra Ab	New 3-aryl-2-hydroxypropionic acid derivative I
TWI262185B (en) *	1999-10-01	2006-09-21	Eisai Co Ltd	Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives
SE0000772D0 (sv) *	2000-03-08	2000-03-08	Astrazeneca Ab	Chemical compounds
TWI311133B (en) *	2001-04-20	2009-06-21	Eisai R&D Man Co Ltd	Carboxylic acid derivativeand the salt thereof
GB0121621D0 (en) *	2001-09-07	2001-10-31	Astrazeneca Ab	Chemical compounds
PL216023B1 (pl) *	2001-09-08	2014-02-28	Astrazeneca Ab	Pochodna benzotiadiazepiny, kompozycja farmaceutyczna zawierajaca pochodna benzotiadiazepiny oraz zastosowania pochodnej benzotiadiazepiny
SE0104333D0 (sv) *	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
GB0314130D0 (en) *	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314075D0 (en) *	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents

2003
- 2003-06-18 GB GBGB0314131.4A patent/GB0314131D0/en not_active Ceased
2004
- 2004-06-16 MX MXPA05013826A patent/MXPA05013826A/es unknown
- 2004-06-16 JP JP2006516434A patent/JP2006527750A/ja active Pending
- 2004-06-16 EP EP04742954A patent/EP1641749A1/en not_active Withdrawn
- 2004-06-16 BR BRPI0411515-5A patent/BRPI0411515A/pt not_active IP Right Cessation
- 2004-06-16 US US10/561,170 patent/US20070099997A1/en not_active Abandoned
- 2004-06-16 CA CA002529251A patent/CA2529251A1/en not_active Abandoned
- 2004-06-16 KR KR1020057024249A patent/KR20060026427A/ko not_active Withdrawn
- 2004-06-16 WO PCT/GB2004/002595 patent/WO2004113284A1/en not_active Ceased
- 2004-06-16 CN CNA2004800232944A patent/CN1835920A/zh active Pending
- 2004-06-16 AU AU2004249485A patent/AU2004249485A1/en not_active Abandoned
- 2004-06-16 RU RU2005141068/04A patent/RU2005141068A/ru not_active Application Discontinuation
- 2004-06-17 AR ARP040102110A patent/AR044800A1/es not_active Application Discontinuation
- 2004-06-17 UY UY28367A patent/UY28367A1/es not_active Application Discontinuation
- 2004-06-18 TW TW093117729A patent/TW200503679A/zh unknown
2005
- 2005-12-07 IL IL172440A patent/IL172440A0/en unknown
- 2005-12-13 NO NO20055927A patent/NO20055927L/no not_active Application Discontinuation
- 2005-12-14 ZA ZA200510196A patent/ZA200510196B/en unknown
- 2005-12-29 CO CO05131305A patent/CO5650240A2/es not_active Application Discontinuation
2006
- 2006-01-16 IS IS8234A patent/IS8234A/is unknown

Also Published As

Publication number	Publication date
GB0314131D0 (en)	2003-07-23
BRPI0411515A (pt)	2006-08-01
US20070099997A1 (en)	2007-05-03
RU2005141068A (ru)	2007-07-27
MXPA05013826A (es)	2006-02-28
UY28367A1 (es)	2005-01-31
CN1835920A (zh)	2006-09-20
IL172440A0 (en)	2006-04-10
TW200503679A (en)	2005-02-01
KR20060026427A (ko)	2006-03-23
WO2004113284A1 (en)	2004-12-29
ZA200510196B (en)	2006-12-27
JP2006527750A (ja)	2006-12-07
EP1641749A1 (en)	2006-04-05
AR044800A1 (es)	2005-10-05
CA2529251A1 (en)	2004-12-29
AU2004249485A1 (en)	2004-12-29
NO20055927L (no)	2006-01-27
CO5650240A2 (es)	2006-06-30

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ATE394094T1 (de)	2008-05-15	Tablette enthaltend 3-((2-ä(4- (hexyloxycarbonylamino-imino-methyl)-phenylamin )-methylü-1-methyl-1h-benzimidazol-5-carbonyl)- pyridin-2-yl-amino)-propionsäure-ethylester oder dessen salze
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NO2014011I1 (no)	2014-05-13	Vortioksetin eller et farmasøytisk akseptabelt syreaddisjonssalt dera
DK1399153T3 (da)	2008-01-07	Farmaceutisk præparat indeholdende orlistat og en fedtsyre eller et salt deraf
EP1785145A4 (en)	2008-08-13	TRANSNASAL COMPOSITION WITH IMMEDIATE EFFECT AND HIGH RESORBIBILITY
NO20022598L (no)	2002-05-31	Krystallisk form av (S)-2-etoksy-3-[4-(2-{4- metansulfonyloksyfenyl}-etoksy)-fenyl]-propansyre
IS8224A (is)	2006-01-10	Amínsölt (-)-2-{[2-(4-hýdroxýfenýl)etýl]-þíó}-3-[4-(2-{4-[(metýlsúlfónýl)oxý]fenoxý}etýl)fenýl]própansýru og notkun þeirra í læknisfræði
IL172440A0 (en)	2006-04-10	Potassium or sodium salt of (-)-2-{[2-(4-hydroxyphenyl) ethyl]thio}-3-[4-(2-{4-[(methylsulfonyl)oxy]phenoxy}ethyl)phenyl]propanoic acid and their use in medicine
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DE60326720D1 (de)	2009-04-30	Sulfonsäuresalze von Mandelsäurederivaten
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DE602004018622D1 (de)	2009-02-05	Pharmazeutische zusammensetzung enthaltend 5-methyl-2-2'-(chloro-6'-fluoroanilino)phenylessigsäure
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ATE439354T1 (de)	2009-08-15	Pharmazeutische salze von reboxetin
SE0101981D0 (sv)	2001-06-01	Pharmaceutical combination
HK1087395A (en)	2006-10-13	Process for the preparation of racemic 2-{[2-(4-hydroxyphenyl)ethyl]thio} -3-{4-(2-{4-[(methylsulfonyl)oxy]phenoxy}ethyl)phenyl]-propanoic acid
TW200640843A (en)	2006-12-01	Therapeutic agents
FR2879312B1 (fr)	2007-08-17	Procede d'ecriture et de restauration de donnees de conservation
NO20035235D0 (no)	2003-11-25	Farmasöytisk kombinasjon omfattende enten (S) -2-etoksy-3- (4- (2- (4-metansulfonyloksyfenyl) etoksy) fenyl) propansyre eller 3- (4- (2- (4-tert-butoksykarbonylaminofenyl) etoksy) fenyl)
IS7058A (is)	2003-11-28	Lyfjablanda sem annaðhvort felur í sér (S)-2-etoxý-3-[4-(2-{4-metansúlfónýloxýfenýl} etoxý)fenýl] própansýru eða 3-{4-[2-(4-tert-bútoxýkarbónýlamínófenýl)etoxý]fenýl}-(S)-2-etoxýprópansýru og bígúaníðlyf
DE60223295D1 (de)	2007-12-13	Lactate biodetektion strip
ITTV20020085A1 (it)	2004-01-22	Dispositivo di incernieramento semplificato ed asta cosi' ottenuta, particolarmente per montature di occhiali
UA10274S (uk)	2005-05-16	Комплект етикеток «українська перцева з медом»