IT1053667B - Procedimento per la preparazione di i oxo isoindoline 3 sostituite e i cxo isoindoline 2 3 sostituite - Google Patents

Procedimento per la preparazione di i oxo isoindoline 3 sostituite e i cxo isoindoline 2 3 sostituite

Info

Publication number: IT1053667B
Authority: IT; Italy
Prior art keywords: alkyl; alkylcycloalkyl; aralkyl; alkoxy; compounds
Prior art date: 1966-12-31

Application number

IT3181866A

Other languages

English (en)

Inventor

P Giraldi

V Mariotti

Original Assignee

Erba Carlo Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1966-12-31

Filing date

1966-12-31

Publication date

1981-10-10

1966-12-31 Priority to IT3181866A priority Critical patent/IT1053667B/it

1966-12-31 Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa

1967-09-22 Priority to CH1326267A priority patent/CH505821A/de

1967-09-22 Priority to ES345784A priority patent/ES345784A1/es

1967-09-22 Priority to BE704182D priority patent/BE704182A/xx

1967-09-22 Priority to SE13036/67A priority patent/SE313054B/xx

1967-09-22 Priority to GB43317/67A priority patent/GB1152928A/en

1967-09-22 Priority to GR670137267A priority patent/GR37267B/el

1967-09-22 Priority to NL6713002A priority patent/NL6713002A/xx

1967-09-25 Priority to FI672547A priority patent/FI51482C/fi

1967-09-25 Priority to FR122111A priority patent/FR7234M/fr

1969-02-03 Priority to US812512*A priority patent/US3624206A/en

1969-03-13 Priority to US840070*A priority patent/US3636223A/en

1981-10-10 Application granted granted Critical

1981-10-10 Publication of IT1053667B publication Critical patent/IT1053667B/it

Links

125000000217 alkyl group Chemical group 0.000 title abstract 4
239000002253 acid Substances 0.000 title abstract 2
125000003545 alkoxy group Chemical group 0.000 title abstract 2
125000005119 alkyl cycloalkyl group Chemical group 0.000 title abstract 2
125000003710 aryl alkyl group Chemical group 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 title abstract 2
150000003839 salts Chemical class 0.000 title abstract 2
KAUMDYDNLPQESC-UHFFFAOYSA-N 3-hydroxy-2,3-dihydroisoindol-1-one Chemical compound C1=CC=C2C(O)NC(=O)C2=C1 KAUMDYDNLPQESC-UHFFFAOYSA-N 0.000 abstract 2
229930003347 Atropine Natural products 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
RKUNBYITZUJHSG-UHFFFAOYSA-N Hyosciamin-hydrochlorid Natural products CN1C(C2)CCC1CC2OC(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-UHFFFAOYSA-N 0.000 abstract 2
RKUNBYITZUJHSG-SPUOUPEWSA-N atropine Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)N2C)C(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-SPUOUPEWSA-N 0.000 abstract 2
229960000396 atropine Drugs 0.000 abstract 2
230000000694 effects Effects 0.000 abstract 2
125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
XQYZDYMELSJDRZ-UHFFFAOYSA-N papaverine Chemical compound C1=C(OC)C(OC)=CC=C1CC1=NC=CC2=CC(OC)=C(OC)C=C12 XQYZDYMELSJDRZ-UHFFFAOYSA-N 0.000 abstract 2
FOYSKATXNROIJA-UHFFFAOYSA-N 1-(2-phenylethoxy)piperidin-4-amine Chemical compound NC1CCN(CC1)OCCC1=CC=CC=C1 FOYSKATXNROIJA-UHFFFAOYSA-N 0.000 abstract 1
BOANLEMBUKYEIR-UHFFFAOYSA-N 3-(4-amino-2-ethoxy-2-phenylpiperidin-1-yl)-2,3-dihydroisoindol-1-one Chemical compound O=C1NC(C2=CC=CC=C12)N1C(CC(CC1)N)(OCC)C1=CC=CC=C1 BOANLEMBUKYEIR-UHFFFAOYSA-N 0.000 abstract 1
229930008281 A03AD01 - Papaverine Natural products 0.000 abstract 1
230000000747 cardiac effect Effects 0.000 abstract 1
239000000812 cholinergic antagonist Substances 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
229960001789 papaverine Drugs 0.000 abstract 1
210000001747 pupil Anatomy 0.000 abstract 1
230000028327 secretion Effects 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IT3181866A 1966-09-23 1966-12-31 Procedimento per la preparazione di i oxo isoindoline 3 sostituite e i cxo isoindoline 2 3 sostituite IT1053667B (it)

Priority Applications (12)

Application Number	Priority Date	Filing Date	Title
IT3181866A IT1053667B (it)	1966-12-31	1966-12-31	Procedimento per la preparazione di i oxo isoindoline 3 sostituite e i cxo isoindoline 2 3 sostituite
ES345784A ES345784A1 (es)	1966-09-23	1967-09-22	Procedimiento para la preparacion de 1-oxo-isoindolinas 3- sustituidas y 1-oxo-isoindolinas 2,3-sustituidas.
BE704182D BE704182A (it)	1966-09-23	1967-09-22
SE13036/67A SE313054B (it)	1966-09-23	1967-09-22
CH1326267A CH505821A (de)	1966-09-23	1967-09-22	Verfahren zur Herstellung neuer 3-substituierter und 2,3-disubstituierter 1-Oxoisoindoline
GB43317/67A GB1152928A (en)	1966-09-23	1967-09-22	New 3-Substituted 1-OXO-Isoindolines and 2,3-Substituted 1-OXO-Isoindolines and Process for their preparation
GR670137267A GR37267B (el)	1966-09-23	1967-09-22	Μεθοδος δια την παρασκευην νεων 3-υποκατεστημενων1-οξο-ισοινδολινων και 2,3-υποκατεστημενων 1-οξο-ισοινδολινων.
NL6713002A NL6713002A (it)	1966-09-23	1967-09-22
FI672547A FI51482C (fi)	1966-09-23	1967-09-25	Menetelmä terapeuttisesti käytettävien 3-substituoitujen 1-okso-isoind oliinien ja 2,3-substituoitujen 1-okso-isoindoliinien valmistamiseksi.
FR122111A FR7234M (it)	1966-09-23	1967-09-25
US812512*A US3624206A (en)	1966-09-23	1969-02-03	3-substituted and 2,3-substituted-1-oxo isoindolines and therapeutic use thereof
US840070*A US3636223A (en)	1966-09-23	1969-03-13	Therapeutic treatment of parkinson's disease

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT3181866A IT1053667B (it)	1966-12-31	1966-12-31	Procedimento per la preparazione di i oxo isoindoline 3 sostituite e i cxo isoindoline 2 3 sostituite

Publications (1)

Publication Number	Publication Date
IT1053667B true IT1053667B (it)	1981-10-10

Family

ID=11234378

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT3181866A IT1053667B (it)	1966-09-23	1966-12-31	Procedimento per la preparazione di i oxo isoindoline 3 sostituite e i cxo isoindoline 2 3 sostituite

Country Status (1)

Country	Link
IT (1)	IT1053667B (it)

1966
- 1966-12-31 IT IT3181866A patent/IT1053667B/it active

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