IT1089773B - 7-alo-3,20-diosso-1,4-pregnadieni e-4-pregneni e procedimento per la loro preparazione - Google Patents

7-alo-3,20-diosso-1,4-pregnadieni e-4-pregneni e procedimento per la loro preparazione

Info

Publication number: IT1089773B
Authority: IT; Italy
Prior art keywords: alpha; alkyl; beta; halo; pregnadiene
Prior art date: 1976-12-22

Application number

IT3094777A

Other languages

English (en)

Original Assignee

Scherico Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-12-22

Filing date

1977-12-20

Publication date

1985-06-18

1976-12-22 Priority claimed from US05/753,257 external-priority patent/US4076708A/en

1977-11-07 Priority claimed from US05/848,856 external-priority patent/US4124707A/en

1977-12-20 Application filed by Scherico Ltd filed Critical Scherico Ltd

1985-06-18 Application granted granted Critical

1985-06-18 Publication of IT1089773B publication Critical patent/IT1089773B/it

Links

229940121363 anti-inflammatory agent Drugs 0.000 title 1
239000002260 anti-inflammatory agent Substances 0.000 title 1
230000000699 topical effect Effects 0.000 title 1
229910052801 chlorine Inorganic materials 0.000 abstract 8
125000000217 alkyl group Chemical group 0.000 abstract 7
229910052794 bromium Inorganic materials 0.000 abstract 6
229910052731 fluorine Inorganic materials 0.000 abstract 6
229910052739 hydrogen Inorganic materials 0.000 abstract 4
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
125000001475 halogen functional group Chemical group 0.000 abstract 2
125000001424 substituent group Chemical group 0.000 abstract 2
WILIRDQOEMCACO-BYZMTCBYSA-N (8s,9s,10r,13r,14s,17s)-17-ethyl-10,13-dimethyl-8,9,11,12,14,15,16,17-octahydro-3h-cyclopenta[a]phenanthrene Chemical compound C1=CC2=CCC=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](CC)[C@@]1(C)CC2 WILIRDQOEMCACO-BYZMTCBYSA-N 0.000 abstract 1
RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
150000001241 acetals Chemical class 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
150000008063 acylals Chemical class 0.000 abstract 1
239000003513 alkali Substances 0.000 abstract 1
229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
125000001188 haloalkyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
150000002373 hemiacetals Chemical class 0.000 abstract 1
229910052740 iodine Inorganic materials 0.000 abstract 1
-1 isonicotinoyl Chemical group 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
125000001444 retinoyl group Chemical group O=C([*])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C1=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Landscapes

Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

IT3094777A 1976-12-22 1977-12-20 7-alo-3,20-diosso-1,4-pregnadieni e-4-pregneni e procedimento per la loro preparazione IT1089773B (it)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US75325676A	1976-12-22	1976-12-22
US05/753,257 US4076708A (en)	1976-12-22	1976-12-22	Process for the preparation of 7α-halogeno-3-oxo-4-dehydro steroids and novel 7α-halogeno derivatives produced thereby
US05/848,856 US4124707A (en)	1976-12-22	1977-11-07	7α-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their manufacture, their use as anti-inflammatory agents, and pharmaceutical formulations useful therefor

Publications (1)

Publication Number	Publication Date
IT1089773B true IT1089773B (it)	1985-06-18

Family

ID=27419445

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT3094777A IT1089773B (it)	1976-12-22	1977-12-20	7-alo-3,20-diosso-1,4-pregnadieni e-4-pregneni e procedimento per la loro preparazione

Country Status (1)

Country	Link
IT (1)	IT1089773B (it)

1977
- 1977-12-20 IT IT3094777A patent/IT1089773B/it active Protection Beyond IP Right Term

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Legal Events

Date	Code	Title	Description
1992-04-27	ITCP	Complementary protection certificate	Free format text: CCP 174
1992-11-13	MEDD	Supplementary protection certificate for pharmaceutical products: granted	Free format text: CCP 174, 19920427; SCHERING-PLOUGH LTD.
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19951130