IT1092577B - Derivati di benzopiranoxantenoni ad attivita anti-androgena e procedimento per la loro preparazione - Google Patents

Derivati di benzopiranoxantenoni ad attivita anti-androgena e procedimento per la loro preparazione

Info

Publication number
IT1092577B
IT1092577B IT7820058A IT2005878A IT1092577B IT 1092577 B IT1092577 B IT 1092577B IT 7820058 A IT7820058 A IT 7820058A IT 2005878 A IT2005878 A IT 2005878A IT 1092577 B IT1092577 B IT 1092577B
Authority
IT
Italy
Prior art keywords
benzopyranoxanthenon
derivatives
procedure
preparation
androgen activity
Prior art date
Application number
IT7820058A
Other languages
English (en)
Italian (it)
Other versions
IT7820058A0 (it
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/800,674 external-priority patent/US4082627A/en
Priority claimed from US05/800,673 external-priority patent/US4081458A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IT7820058A0 publication Critical patent/IT7820058A0/it
Application granted granted Critical
Publication of IT1092577B publication Critical patent/IT1092577B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/05—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/07—Oxygen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/09—Nitrogen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/11—Halogen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/25—Reduction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Electrochemistry (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IT7820058A 1977-05-26 1978-02-07 Derivati di benzopiranoxantenoni ad attivita anti-androgena e procedimento per la loro preparazione IT1092577B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/800,674 US4082627A (en) 1977-05-26 1977-05-26 Electrolytic reduction of dihydrobenzopyranoxanthenones
US05/800,673 US4081458A (en) 1977-05-26 1977-05-26 Anti-androgen compounds

Publications (2)

Publication Number Publication Date
IT7820058A0 IT7820058A0 (it) 1978-02-07
IT1092577B true IT1092577B (it) 1985-07-12

Family

ID=27122240

Family Applications (1)

Application Number Title Priority Date Filing Date
IT7820058A IT1092577B (it) 1977-05-26 1978-02-07 Derivati di benzopiranoxantenoni ad attivita anti-androgena e procedimento per la loro preparazione

Country Status (25)

Country Link
JP (1) JPS53147099A (de)
AR (1) AR225133A1 (de)
AT (1) AT361920B (de)
AU (1) AU515424B2 (de)
BG (1) BG30020A3 (de)
CS (1) CS214887B2 (de)
DD (1) DD134766A5 (de)
DE (1) DE2804682A1 (de)
DK (1) DK52978A (de)
ES (1) ES466756A1 (de)
FR (1) FR2392026A1 (de)
GB (1) GB1593643A (de)
GR (1) GR69964B (de)
HU (1) HU180230B (de)
IE (1) IE46392B1 (de)
IL (1) IL53990A (de)
IT (1) IT1092577B (de)
NL (1) NL7801392A (de)
NZ (1) NZ186387A (de)
PL (1) PL110214B1 (de)
PT (1) PT67611B (de)
RO (1) RO74948A (de)
SE (1) SE7801419L (de)
SU (3) SU793395A3 (de)
YU (1) YU26378A (de)

Also Published As

Publication number Publication date
JPS53147099A (en) 1978-12-21
GB1593643A (en) 1981-07-22
SE7801419L (sv) 1978-11-27
YU26378A (en) 1983-02-28
PT67611B (en) 1979-07-16
AU515424B2 (en) 1981-04-02
ES466756A1 (es) 1979-10-01
CS214887B2 (en) 1982-06-25
NZ186387A (en) 1979-06-08
SU793395A3 (ru) 1980-12-30
IT7820058A0 (it) 1978-02-07
FR2392026B1 (de) 1980-12-26
PL204508A1 (pl) 1979-01-02
RO74948A (ro) 1980-10-30
NL7801392A (nl) 1978-11-28
DD134766A5 (de) 1979-03-21
PL110214B1 (en) 1980-07-31
FR2392026A1 (fr) 1978-12-22
IE780232L (en) 1978-11-26
SU818485A3 (ru) 1981-03-30
GR69964B (de) 1982-07-22
DK52978A (da) 1978-11-27
AT361920B (de) 1981-04-10
AU3302278A (en) 1979-08-16
IL53990A (en) 1981-09-13
IE46392B1 (en) 1983-06-01
DE2804682A1 (de) 1978-11-30
SU927117A3 (ru) 1982-05-07
PT67611A (en) 1978-03-01
AR225133A1 (es) 1982-02-26
HU180230B (en) 1983-02-28
BG30020A3 (en) 1981-03-16
ATA85178A (de) 1980-09-15

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