IT1100950B - Processo di fabbricazione di sali di eparina semplici contenenti cationi metallici diversi dal sodio,oppure misti - Google Patents

Processo di fabbricazione di sali di eparina semplici contenenti cationi metallici diversi dal sodio,oppure misti

Info

Publication number: IT1100950B
Authority: IT; Italy
Prior art keywords: heparine; sodium; mixed; manufacturing process; salts containing
Prior art date: 1973-04-13

Application number

IT30216/78A

Other languages

English (en)

Other versions

IT7830216A0 (it

Inventor

Jean Choay

Jean Amyot

Goulay Louis

Original Assignee

Choay Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-04-13

Filing date

1978-11-27

Publication date

1985-09-28

1973-04-13 Priority claimed from FR7313581A external-priority patent/FR2225149A1/fr

1973-04-13 Priority claimed from FR7313580A external-priority patent/FR2225406A1/fr

1978-11-27 Application filed by Choay Sa filed Critical Choay Sa

1978-11-27 Publication of IT7830216A0 publication Critical patent/IT7830216A0/it

1985-09-28 Application granted granted Critical

1985-09-28 Publication of IT1100950B publication Critical patent/IT1100950B/it

Links

HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical class OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
150000001457 metallic cations Chemical class 0.000 title 1
229910052708 sodium Inorganic materials 0.000 title 1
239000011734 sodium Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Materials Engineering (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Polymers & Plastics (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

IT30216/78A 1973-04-13 1978-11-27 Processo di fabbricazione di sali di eparina semplici contenenti cationi metallici diversi dal sodio,oppure misti IT1100950B (it)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR7313581A FR2225149A1 (en)	1973-04-13	1973-04-13	Sodium-free heparin salts - by cation exchange of sodium salts, anticoagulants without side-effects
FR7313580A FR2225406A1 (en)	1973-04-13	1973-04-13	Sodium-free heparin salts - by cation exchange of sodium salts, anticoagulants without side-effects

Publications (2)

Publication Number	Publication Date
IT7830216A0 IT7830216A0 (it)	1978-11-27
IT1100950B true IT1100950B (it)	1985-09-28

Family

ID=26217686

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT30216/78A IT1100950B (it)	1973-04-13	1978-11-27	Processo di fabbricazione di sali di eparina semplici contenenti cationi metallici diversi dal sodio,oppure misti

Country Status (12)

Country	Link
US (1)	US4168377A (it)
JP (1)	JPS5052217A (it)
AR (1)	AR210456A1 (it)
AU (1)	AU504218B2 (it)
BE (1)	BE813707A (it)
CA (1)	CA1042001A (it)
CH (1)	CH597259A5 (it)
DE (1)	DE2417859C2 (it)
ES (1)	ES425303A1 (it)
GB (1)	GB1471482A (it)
IT (1)	IT1100950B (it)
NL (1)	NL7405033A (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE47169B1 (en) *	1977-08-08	1984-01-11	Choay Sa	Purified calcium salts of heparin
FR2440376A1 (fr) *	1978-11-06	1980-05-30	Choay Sa	Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir
US4500519A (en) *	1978-11-06	1985-02-19	Choay S.A.	Mucopolysaccharides having biological properties, preparation and method of use
US4692435A (en) *	1978-11-06	1987-09-08	Choay, S.A.	Mucopolysaccharide composition having a regulatory action on coagulation, medicament containing same and process of preparation
SE449753B (sv) *	1978-11-06	1987-05-18	Choay Sa	Mukopolysackaridkomposition med reglerande verkan pa koagulation, lekemedel innehallande densamma samt forfarande for framstellning derav
IT1141263B (it) *	1980-02-29	1986-10-01	Italfarmaco Spa	Metodo per la preparazione di eparinato di calcio
US4405612A (en) *	1980-05-23	1983-09-20	Riker Laboratories, Inc.	Heparin web compositions
US4479799A (en) *	1981-05-21	1984-10-30	Riker Laboratories, Inc.	Hypodermic syringe containing microfibers of an amorphous heparin salt
SE8702254D0 (sv) *	1987-05-29	1987-05-29	Kabivitrum Ab	Novel heparin derivatives
US20050090662A1 (en) *	1997-01-15	2005-04-28	Beavers Ellington M.	Method of making free acids from polysaccharide salts
US6969705B2 (en)	2000-07-21	2005-11-29	Aventis Pharma S.A.	Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
US20040171819A1 (en) *	2002-10-10	2004-09-02	Aventis Pharma S.A.	Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
US7956046B2 (en) *	2003-07-24	2011-06-07	Aventis Pharma S.A.	Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them
CN105218704A (zh) *	2015-09-29	2016-01-06	山东绅联生物科技有限公司	一种肝素钙的制备方法
EP3791884A1 (en)	2019-09-16	2021-03-17	Oskar Bunz	Combination of heparin and magnesium salt for the treatment of viral infections
CN110878129B (zh) *	2019-12-06	2022-02-01	中国科学院烟台海岸带研究所	一种氨基葡萄糖肝素盐及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2623001A (en) *	1949-04-07	1952-12-23	Bengt E G V Sylven	Preparing heparin
US3192114A (en) *	1952-06-21	1965-06-29	Leo Ab	Preparations with protracted acth-effect
AT222807B (de) *	1960-08-26	1962-08-10	Fo We Forschungs Und Verwertun	Verfahren zur Herstellung eines therapeutisch wirksamen Produktes
US3482014A (en) *	1966-06-29	1969-12-02	Canada Packers Ltd	Orally active heparin and method for making and using same
US3506642A (en) *	1967-07-03	1970-04-14	Canada Packers Ltd	Stable orally active heparinoid complexes
FR1538204A (fr) *	1967-09-27	1968-08-30	Canada Packers Ltd	Dérivés de l'héparine et procédés pour leur préparation
FR6853M (it) *	1967-12-08	1969-04-08

1974
- 1974-04-09 CA CA197,189A patent/CA1042001A/en not_active Expired
- 1974-04-10 AR AR253259A patent/AR210456A1/es active
- 1974-04-10 US US05/459,712 patent/US4168377A/en not_active Expired - Lifetime
- 1974-04-11 NL NL7405033A patent/NL7405033A/xx not_active Application Discontinuation
- 1974-04-11 GB GB1620974A patent/GB1471482A/en not_active Expired
- 1974-04-11 AU AU67836/74A patent/AU504218B2/en not_active Expired
- 1974-04-11 CH CH511774A patent/CH597259A5/xx not_active IP Right Cessation
- 1974-04-11 DE DE2417859A patent/DE2417859C2/de not_active Expired
- 1974-04-12 BE BE143197A patent/BE813707A/xx not_active IP Right Cessation
- 1974-04-12 JP JP49040463A patent/JPS5052217A/ja active Pending
- 1974-04-13 ES ES425303A patent/ES425303A1/es not_active Expired
1978
- 1978-11-27 IT IT30216/78A patent/IT1100950B/it active

Also Published As

Publication number	Publication date
AU504218B2 (en)	1979-10-04
CH597259A5 (it)	1978-03-31
CA1042001A (en)	1978-11-07
JPS5052217A (it)	1975-05-09
NL7405033A (it)	1974-10-15
AU6783674A (en)	1975-10-16
AR210456A1 (es)	1977-08-15
DE2417859A1 (de)	1974-10-24
BE813707A (fr)	1974-10-14
IT7830216A0 (it)	1978-11-27
DE2417859C2 (de)	1984-09-20
US4168377A (en)	1979-09-18
GB1471482A (en)	1977-04-27
ES425303A1 (es)	1976-12-16

Publication	Publication Date	Title
IT8021616A0 (it)	1980-04-24	Procedimento di produzione di copoliesteri carbonati.
CS178822B2 (en)	1977-10-31	Mixture for coating glass fibres.
IT7830216A0 (it)	1978-11-27	Processo di fabbricazione di sali di eparina semplici contenenti cationi metallici diversi dal sodio, oppure misti.
MX146167A (es)	1982-05-21	Composicion acuosa mejorada para aprestar fibras de vidrio
CA1032679A (en)	1978-06-06	Process for producing aqueous coating compositions
IT1013149B (it)	1977-03-30	Processo di fabbricazione di metilmercaptano
IT1010408B (it)	1977-01-10	Processo per la preparazione di formaldeide
BR7500317A (pt)	1975-11-04	Processo de preparacao de novos fenolacetais
BR7505865A (pt)	1976-08-03	Processo para a preparacao de corantes disazo
BR7400243D0 (pt)	1974-08-22	Processo de preparacao de gas redutor
BR7407642D0 (pt)	1975-07-15	Aperfeicoamentos no processo de preparacao de clorato de sodio por eletrolise
BR7405967D0 (pt)	1975-05-13	Processo de preparacao de percarbonato de sodio
IT1042237B (it)	1980-01-30	Processo per la preparazione di ciclobutanoni
IT1010299B (it)	1977-01-10	Processo per la preparazione di formaldeide
BR7502595A (pt)	1976-03-09	Processo de preparacao de alcoois primarios
IT1050008B (it)	1981-03-10	Processo per la preparazione di coloranti ossazinici basici
BR7501346A (pt)	1975-12-09	Processo para a preparacao de um composto de s-triazol-(3,4-b)-benzo-tiazol
BR7503239A (pt)	1976-04-27	Processo para a preparacao de 3-triclorometil-5-etoxi-1,2,4-tiadiazol
BR7505416A (pt)	1976-08-03	Processo para preparacao de percarbonato de sodio estabilizado
BR7501309A (pt)	1976-08-03	Processo para preparacao de 2,6-diclorobenzoatos acetilenicos
BR7405160D0 (pt)	1975-01-21	Processo para a preparacao de garamina com amino protegida
IT1038088B (it)	1979-11-20	Processo per la preparazione di composti 4 amino 1.8 naftalimidici
IT1043494B (it)	1980-02-20	Processo per la preparazione di polieteri
IT1038087B (it)	1979-11-20	Processo per la preparazione di composti 4 amino 1.8 nafial n arilimidici
IT1043499B (it)	1980-02-20	Processo per la preparazione di metanolo