IT1125421B - Polipeptidi terapeuticamente attivi,o loro sali d'addizione con acidi,e procedimento per produrre tali composti - Google Patents

Polipeptidi terapeuticamente attivi,o loro sali d'addizione con acidi,e procedimento per produrre tali composti

Info

Publication number: IT1125421B
Authority: IT; Italy
Prior art keywords: acids; compounds; procedure; produce; addition salts
Prior art date: 1978-09-28

Application number

IT26111/79A

Other languages

English (en)

Other versions

IT7926111A0 (it

Inventor

Hans Kofod

Original Assignee

Nordisk Insulinlab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-09-28

Filing date

1979-09-28

Publication date

1986-05-14

1979-09-28 Application filed by Nordisk Insulinlab filed Critical Nordisk Insulinlab

1979-09-28 Publication of IT7926111A0 publication Critical patent/IT7926111A0/it

1986-05-14 Application granted granted Critical

1986-05-14 Publication of IT1125421B publication Critical patent/IT1125421B/it

Links

239000002253 acid Substances 0.000 title 1
150000007513 acids Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
229920001184 polypeptide Polymers 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/645—Secretins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/66—Thymopoietins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IT26111/79A 1978-09-28 1979-09-28 Polipeptidi terapeuticamente attivi,o loro sali d'addizione con acidi,e procedimento per produrre tali composti IT1125421B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK430478		1978-09-28

Publications (2)

Publication Number	Publication Date
IT7926111A0 IT7926111A0 (it)	1979-09-28
IT1125421B true IT1125421B (it)	1986-05-14

Family

ID=8132257

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IT26111/79A IT1125421B (it)	1978-09-28	1979-09-28	Polipeptidi terapeuticamente attivi,o loro sali d'addizione con acidi,e procedimento per produrre tali composti
IT26112/79A IT1125422B (it)	1978-09-28	1979-09-28	Polipeptidi terapeuticamente attivi,o sali d'addizione con acidi,e procedimento per produrre tali composti

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IT26112/79A IT1125422B (it)	1978-09-28	1979-09-28	Polipeptidi terapeuticamente attivi,o sali d'addizione con acidi,e procedimento per produrre tali composti

Country Status (16)

Country	Link
US (1)	US4356119A (it)
JP (2)	JPS5569550A (it)
AT (1)	AT375338B (it)
AU (2)	AU533684B2 (it)
BE (2)	BE879087A (it)
CA (2)	CA1158640A (it)
CH (2)	CH648568A5 (it)
DE (2)	DE2939135A1 (it)
ES (2)	ES484926A1 (it)
FI (2)	FI68245C (it)
FR (2)	FR2437399A1 (it)
GB (2)	GB2031436B (it)
IT (2)	IT1125421B (it)
NL (2)	NL7907187A (it)
NO (2)	NO148923C (it)
SE (2)	SE7907939L (it)

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA685075A (en) *		1964-04-21	Schwyzer Robert	Polypeptides and process for their manufacture
CA798855A (en) *		1968-11-12	Bernardi Luigi	Process for preparing a new undecapeptide
CA616330A (en) *		1961-03-14	Schwyzer Robert	Polypeptide and derivatives thereof and process for their manfuacture
GB1064417A (en) *	1963-12-09	1967-04-05	Kyowa Hakko Kogyo Kk	Process for the preparation of copolypeptides
US3400118A (en) *	1966-05-27	1968-09-03	Squibb & Sons Inc	Intermediates in the preparation of secretin
US3832337A (en) *	1970-07-28	1974-08-27	Squibb & Sons Inc	Peptide enzyme inhibitors
US3856770A (en) *	1972-03-08	1974-12-24	Akzona Inc	Psychopharmacologically active tetra-, penta-, hexa-, and heptapeptides
NL175174C (nl) *	1972-03-31	1984-10-01	Akzo Nv	Werkwijze ter bereiding van een farmaceutisch preparaat met psychofarmacologische werking, dat een peptide of peptide-derivaat als actief bestanddeel bevat, alsmede een werkwijze ter bereiding van deze peptiden.
NL175988C (nl) *	1972-05-24	1985-02-01	Akzo Nv	Werkwijze ter bereiding van een farmaceutisch preparaat met psychofarmacologische werking, dat een peptide of peptide-derivaat dat afgeleid is van een de aminozuren 4-10 omvattend, fragment van adrenocorticotroop hormoon als actief bestanddeel bevat, alsmede een werkwijze ter bereiding van deze peptiden.
NL175618C (nl) *	1972-07-15	1984-12-03	Akzo Nv	Werkwijze ter bereiding van een farmaceutisch preparaat met psychofarmacologische werking, dat een peptide of peptide-derivaat bevat, alsmede een werkwijze ter bereiding van dergelijke peptiden.
DE2315271C3 (de) *	1973-03-27	1975-09-11	Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen	L- Norleucin-13-Motilin, Verfahren zu dessen Herstellung und dasselbe enthaltendes Mittel
GB1532211A (en) *	1974-10-25	1978-11-15	Wellcome Found	Lh-rh peptide analogues
US3975365A (en) *	1975-01-27	1976-08-17	G. D. Searle & Co.	Inhibitory octapeptides angiotensin II
DE2602443A1 (de) *	1975-04-04	1976-10-21	Univ California	Biologisch aktive polypeptide
US4171299A (en) *	1975-04-04	1979-10-16	The Regents Of The University Of California	Polypeptide agents for blocking the human allergic response
US4058512A (en) *	1975-04-28	1977-11-15	Ab Kabi	Synthetic peptides having growth promoting activity
US4024121A (en) *	1976-01-27	1977-05-17	Schally Andrew Victor	(Pyro)-Glu-His-Trp-D-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHR and intermediates
SE436645C (sv) *	1976-04-29	1996-07-22	Bonnierfoeretagen Ab	Antigeniskt aktiv polypeptid, som kan användas vid cancerdiagnosticering och vid framställning av antikroppar
US4110321A (en) *	1976-07-12	1978-08-29	Folkers Karl	Synthetic tridecapeptide [Gln4 ]-neurotensin having hormonal activity
US4086220A (en) *	1976-08-09	1978-04-25	G. D. Searle & Co.	Fragments of secretin

1979
- 1979-09-24 US US06/078,424 patent/US4356119A/en not_active Expired - Lifetime
- 1979-09-25 SE SE7907939A patent/SE7907939L/ not_active Application Discontinuation
- 1979-09-25 SE SE7907938A patent/SE7907938L/ not_active Application Discontinuation
- 1979-09-26 AU AU51246/79A patent/AU533684B2/en not_active Ceased
- 1979-09-26 AU AU51245/79A patent/AU526149B2/en not_active Ceased
- 1979-09-26 FI FI793002A patent/FI68245C/fi not_active IP Right Cessation
- 1979-09-26 FI FI793001A patent/FI68244C/fi not_active IP Right Cessation
- 1979-09-27 GB GB7933541A patent/GB2031436B/en not_active Expired
- 1979-09-27 CA CA000336694A patent/CA1158640A/en not_active Expired
- 1979-09-27 NO NO793112A patent/NO148923C/no unknown
- 1979-09-27 DE DE19792939135 patent/DE2939135A1/de not_active Withdrawn
- 1979-09-27 CH CH8715/79A patent/CH648568A5/de not_active IP Right Cessation
- 1979-09-27 CA CA000336681A patent/CA1140116A/en not_active Expired
- 1979-09-27 NO NO793111A patent/NO148922C/no unknown
- 1979-09-27 NL NL7907187A patent/NL7907187A/nl not_active Application Discontinuation
- 1979-09-27 GB GB7933540A patent/GB2031435B/en not_active Expired
- 1979-09-27 FR FR7924077A patent/FR2437399A1/fr active Granted
- 1979-09-27 NL NL7907188A patent/NL7907188A/nl not_active Application Discontinuation
- 1979-09-27 AT AT0634679A patent/AT375338B/de not_active IP Right Cessation
- 1979-09-27 CH CH8714/79A patent/CH648567A5/de not_active IP Right Cessation
- 1979-09-27 DE DE19792939109 patent/DE2939109A1/de not_active Withdrawn
- 1979-09-27 FR FR7924078A patent/FR2437400A1/fr active Granted
- 1979-09-28 IT IT26111/79A patent/IT1125421B/it active
- 1979-09-28 JP JP12522079A patent/JPS5569550A/ja active Pending
- 1979-09-28 ES ES484926A patent/ES484926A1/es not_active Expired
- 1979-09-28 BE BE0/197392A patent/BE879087A/fr not_active IP Right Cessation
- 1979-09-28 ES ES484928A patent/ES484928A1/es not_active Expired
- 1979-09-28 IT IT26112/79A patent/IT1125422B/it active
- 1979-09-28 JP JP12522179A patent/JPS5576849A/ja active Pending
- 1979-09-28 BE BE0/197391A patent/BE879086A/fr not_active IP Right Cessation

Also Published As

Publication number	Publication date
CH648568A5 (de)	1985-03-29
AT375338B (de)	1984-07-25
US4356119A (en)	1982-10-26
FR2437399B1 (it)	1983-01-28
FR2437400B1 (it)	1984-06-15
NO793112L (no)	1980-03-31
CA1158640A (en)	1983-12-13
JPS5569550A (en)	1980-05-26
NO148923C (no)	1984-01-11
GB2031436A (en)	1980-04-23
GB2031435B (en)	1982-11-10
BE879087A (fr)	1980-03-28
JPS5576849A (en)	1980-06-10
IT7926111A0 (it)	1979-09-28
AU533684B2 (en)	1983-12-08
CH648567A5 (de)	1985-03-29
IT7926112A0 (it)	1979-09-28
FI793001A7 (fi)	1980-03-29
NL7907188A (nl)	1980-04-01
FI68245B (fi)	1985-04-30
NL7907187A (nl)	1980-04-01
AU526149B2 (en)	1982-12-16
AU5124579A (en)	1980-04-03
CA1140116A (en)	1983-01-25
FR2437400A1 (fr)	1980-04-25
ES484926A1 (es)	1980-07-01
SE7907938L (sv)	1980-03-29
FI68244C (fi)	1985-08-12
GB2031435A (en)	1980-04-23
FI68245C (fi)	1985-08-12
ATA634679A (de)	1983-12-15
AU5124679A (en)	1980-04-03
BE879086A (fr)	1980-03-28
FI68244B (fi)	1985-04-30
DE2939135A1 (de)	1980-04-17
NO148923B (no)	1983-10-03
FR2437399A1 (fr)	1980-04-25
GB2031436B (en)	1982-10-20
NO148922B (no)	1983-10-03
FI793002A7 (fi)	1980-03-29
DE2939109A1 (de)	1980-04-10
NO793111L (no)	1980-03-31
NO148922C (no)	1984-01-11
ES484928A1 (es)	1980-07-01
SE7907939L (sv)	1980-03-29
IT1125422B (it)	1986-05-14

Publication	Publication Date	Title
NO803337L (no)	1977-09-26	Analogifremgangsmaate for fremstilling av nye terapeutisk virksomme benzimidazolylacetohydroksamsyrer
IT1142170B (it)	1986-10-08	Composti eterosiclici dotati di attivita' farmacologica e procedimento per la loro preparazione
BE879106A (fr)	1980-02-01	Derives d'acides quinoleine carboxylique substitue
IT1115158B (it)	1986-02-03	Acidi 4-tiazolidini-carbossilici anti-ipertenzione
IT8125614A0 (it)	1981-12-15	Acidi treo-3-ammino-2-idrossibutanoilammi no-acetici utili come farmaci.
FR2303597A1 (fr)	1976-10-08	Procede de preparation d'anhydrides d'acides carboxyliques
IT1120442B (it)	1986-03-26	Procedimento per produrre acidi arilpiruvici
IT1194632B (it)	1988-09-22	Acidi n-(idrossimetil)-amminoalcan-difosfonici e loro impiego come stabilizzanti
IT7948950A0 (it)	1979-05-07	Acidi lattamo-n-acetici e loro ammidi procedimento per prepararli e composizioni terapeutiche che licontengono
IT1076799B (it)	1985-04-27	Acidi n-fosfon-metilen-monoammino-alcan-mono- e -poli-fosfonici oppure acidi n-fosfon-metilen-diammino-alcan-polifosfonici e anche procedimenti per la loro preparazione
NO792139L (no)	1979-12-28	Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazoloksamsyre-derivater
FR2336366A1 (fr)	1977-07-22	Procede de preparation d'anhydrides d'acides carboxyliques
NO147949C (no)	1983-07-13	Kontinuerlig fremgangsmaate for fremstilling av karboksylpersyrer.
IT1157187B (it)	1987-02-11	Peptidi loro sali di addizione con acidi e procedimento per produrli
IT8025538A0 (it)	1980-10-23	Sali di acidi dialo-2-chinossalincarbossilici.
IT1116890B (it)	1986-02-10	Acido 2-para-prenilfenil-propionico e suoi sali ad attivit'analgesica e anti-infiammatoria
IT1110819B (it)	1986-01-06	Procedimento per la preparazione di acidi benzen-carbossilici
IT1125422B (it)	1986-05-14	Polipeptidi terapeuticamente attivi,o sali d'addizione con acidi,e procedimento per produrre tali composti
NO164243C (no)	1990-09-19	Analogifremgangsmaate for fremstilling av nye terapeutisk aktive 16,17-acetalsubstituerte pregnan-21-oinsyrederivater
IT1122746B (it)	1986-04-23	Procedimento perfezionato per la preparazione di 4(5)-idrossimetil-5(4)-alchilinferiore-imidazoli e deli loro sali di addizione con acidi
IT1128706B (it)	1986-06-04	Procedimento per la preparazione di acidi arilpropionici dotati di attivita' farmacologica
IT1078873B (it)	1985-05-08	Processo per produrre acidi carbossilici alifatici fosfonico-sostituiti relativi prodotti e loro uso
IT1188988B (it)	1988-01-28	Composti 1(2h)-isochinolonici e loro sali di addizione con acidi
IT7823904A0 (it)	1978-05-26	Acidi chinolinici ad attivita'antiinfiammatoria e procedimento per la loro preparazione.
IT1209145B (it)	1989-07-10	Procedimento per migliorare le caratteristiche farmacologiche degli acidi aril-alcanoici adattivita' analgesica e anti-infiammatoria.