IT1130554B - Mercapto acil-derivati della prolina e dell'acido pipecolico cheto-sostituti - Google Patents

Mercapto acil-derivati della prolina e dell'acido pipecolico cheto-sostituti

Info

Publication number: IT1130554B
Authority: IT; Italy
Prior art keywords: pipecolic acid; mercapto; alkyl; lower alkyl; acid derivs
Prior art date: 1980-03-18

Application number

IT20743/80A

Other languages

English (en)

Other versions

IT8020743A0 (it

Inventor

Miguel Angel Ondetti

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-03-18

Filing date

1980-03-18

Publication date

1986-06-18

1980-03-18 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1980-03-18 Priority to IT20743/80A priority Critical patent/IT1130554B/it

1980-03-18 Publication of IT8020743A0 publication Critical patent/IT8020743A0/it

1986-06-18 Application granted granted Critical

1986-06-18 Publication of IT1130554B publication Critical patent/IT1130554B/it

Links

HXEACLLIILLPRG-YFKPBYRVSA-N L-pipecolic acid Chemical compound [O-]C(=O)[C@@H]1CCCC[NH2+]1 HXEACLLIILLPRG-YFKPBYRVSA-N 0.000 title abstract 2
ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 title abstract 2
HXEACLLIILLPRG-RXMQYKEDSA-N l-pipecolic acid Natural products OC(=O)[C@H]1CCCCN1 HXEACLLIILLPRG-RXMQYKEDSA-N 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 5
102000005862 Angiotensin II Human genes 0.000 abstract 1
101800000734 Angiotensin-1 Proteins 0.000 abstract 1
102400000344 Angiotensin-1 Human genes 0.000 abstract 1
101800000733 Angiotensin-2 Proteins 0.000 abstract 1
101100097467 Arabidopsis thaliana SYD gene Proteins 0.000 abstract 1
CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 1
101100495925 Schizosaccharomyces pombe (strain 972 / ATCC 24843) chr3 gene Proteins 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
ORWYRWWVDCYOMK-HBZPZAIKSA-N angiotensin I Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC(C)C)C(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C1=CC=C(O)C=C1 ORWYRWWVDCYOMK-HBZPZAIKSA-N 0.000 abstract 1
229950006323 angiotensin ii Drugs 0.000 abstract 1
229940030600 antihypertensive agent Drugs 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical compound O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Landscapes

Pyrrole Compounds (AREA)
Peptides Or Proteins (AREA)

IT20743/80A 1980-03-18 1980-03-18 Mercapto acil-derivati della prolina e dell'acido pipecolico cheto-sostituti IT1130554B (it)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
IT20743/80A IT1130554B (it)	1980-03-18	1980-03-18	Mercapto acil-derivati della prolina e dell'acido pipecolico cheto-sostituti

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT20743/80A IT1130554B (it)	1980-03-18	1980-03-18	Mercapto acil-derivati della prolina e dell'acido pipecolico cheto-sostituti

Publications (2)

Publication Number	Publication Date
IT8020743A0 IT8020743A0 (it)	1980-03-18
IT1130554B true IT1130554B (it)	1986-06-18

Family

ID=11171393

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT20743/80A IT1130554B (it)	1980-03-18	1980-03-18	Mercapto acil-derivati della prolina e dell'acido pipecolico cheto-sostituti

Country Status (1)

Country	Link
IT (1)	IT1130554B (it)

1980
- 1980-03-18 IT IT20743/80A patent/IT1130554B/it active

Also Published As

Publication number	Publication date
IT8020743A0 (it)	1980-03-18

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