IT1203873B - Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e - Google Patents

Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e

Info

Publication number
IT1203873B
IT1203873B IT8720032A IT2003287A IT1203873B IT 1203873 B IT1203873 B IT 1203873B IT 8720032 A IT8720032 A IT 8720032A IT 2003287 A IT2003287 A IT 2003287A IT 1203873 B IT1203873 B IT 1203873B
Authority
IT
Italy
Prior art keywords
pulmonary surfactant
preparation
pharmaceutical compositions
natural pulmonary
surfactant contain
Prior art date
Application number
IT8720032A
Other languages
English (en)
Other versions
IT8720032A0 (it
Inventor
Robertson Bengt
Curstedt Tore
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of IT8720032A0 publication Critical patent/IT8720032A0/it
Priority to IT8720032A priority Critical patent/IT1203873B/it
Priority to FI881508A priority patent/FI92905C/fi
Priority to DE198888105232T priority patent/DE286011T1/de
Priority to ES88105232T priority patent/ES2004856T3/es
Priority to AT88105232T priority patent/ATE99949T1/de
Priority to EP88105232A priority patent/EP0286011B1/en
Priority to DE3886970T priority patent/DE3886970T2/de
Priority to US07/177,771 priority patent/US5024995A/en
Priority to PH8836751A priority patent/PH25300A/en
Priority to IE100888A priority patent/IE61384B1/en
Priority to NZ224146A priority patent/NZ224146A/en
Priority to ZA882416A priority patent/ZA882416B/xx
Priority to CA000563558A priority patent/CA1320440C/en
Priority to AU14337/88A priority patent/AU619462B2/en
Priority to DK198801900A priority patent/DK172921B1/da
Priority to PT87188A priority patent/PT87188B/pt
Priority to NO881515A priority patent/NO174733C/no
Priority to JP63086214A priority patent/JP2700323B2/ja
Priority to MYPI88000361A priority patent/MY103260A/en
Priority to EG20388A priority patent/EG19626A/xx
Application granted granted Critical
Publication of IT1203873B publication Critical patent/IT1203873B/it
Priority to GR89300026T priority patent/GR890300026T1/el
Priority to HU95P/P00628P priority patent/HU211950A9/hu
Priority to HK98106244.4A priority patent/HK1007103B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/42—Respiratory system, e.g. lungs, bronchi or lung cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0082—Lung surfactant, artificial mucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IT8720032A 1987-04-08 1987-04-08 Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e IT1203873B (it)

Priority Applications (23)

Application Number Priority Date Filing Date Title
IT8720032A IT1203873B (it) 1987-04-08 1987-04-08 Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e
FI881508A FI92905C (fi) 1987-04-08 1988-03-30 Menetelmä eläinperäisen keuhkojen pinta-aktiivisen aineen valmistamiseksi
DE198888105232T DE286011T1 (de) 1987-04-08 1988-03-31 Natuerliches oberflaechenwirksames lungenpraeparat, verfahren zu seiner herstellung und pharmazeutische zusammensetzungen.
ES88105232T ES2004856T3 (es) 1987-04-08 1988-03-31 Agente tensioactivo pulmonar natural, procedimiento de preparacion y composiciones farmaceuticas.
AT88105232T ATE99949T1 (de) 1987-04-08 1988-03-31 Natuerliches oberflaechenwirksames lungenpraeparat, verfahren zu seiner herstellung und pharmazeutische zusammensetzungen.
EP88105232A EP0286011B1 (en) 1987-04-08 1988-03-31 Natural pulmonary surfactant, method of preparation and pharmaceutical compositions
DE3886970T DE3886970T2 (de) 1987-04-08 1988-03-31 Natürliches oberflächenwirksames Lungenpräparat, Verfahren zu seiner Herstellung und pharmazeutische Zusammensetzungen.
US07/177,771 US5024995A (en) 1987-04-08 1988-04-05 Natural pulmonary surfactant, method of preparation and pharamceutical compositions
NZ224146A NZ224146A (en) 1987-04-08 1988-04-06 Pulmonary surfactant comprised of protein and lipid-fractions
IE100888A IE61384B1 (en) 1987-04-08 1988-04-06 Natural pulmonary surfactant, method of preparation and pharmaceutical compositions
PH8836751A PH25300A (en) 1987-04-08 1988-04-06 Natural pulmonary surfactant, method of preparation and pharmaceutical compositions
JP63086214A JP2700323B2 (ja) 1987-04-08 1988-04-07 肺動脈界面活性剤、その調製方法、及び薬剤組成物
CA000563558A CA1320440C (en) 1987-04-08 1988-04-07 Natural pulmonary surfactant, method of preparation and pharmaceutical compositions
AU14337/88A AU619462B2 (en) 1987-04-08 1988-04-07 Natural pulmonary surfactant, method of preparation and pharmaceutical compositions
DK198801900A DK172921B1 (da) 1987-04-08 1988-04-07 Naturligt, pulmonart, overfladeaktivt middel, fremgangsmåde til fremstilling heraf samt farmaceutiske midler indeholdende d
PT87188A PT87188B (pt) 1987-04-08 1988-04-07 Processo para a preparacao de um tensioactivo pulmonar natural e de composicoes farmaceuticas que o contem
NO881515A NO174733C (no) 1987-04-08 1988-04-07 Fremgangsmåte ved fremstilling av pulmonar surfaktant
ZA882416A ZA882416B (en) 1987-04-08 1988-04-07 Natural pulmonary surfactant,method of preparation and pharmaceutical compositions
MYPI88000361A MY103260A (en) 1987-04-08 1988-04-08 Natural pulmonary surfactant, mathod of preparation and pharmaecutical compositions
EG20388A EG19626A (en) 1987-04-08 1988-04-10 Natural pulmonary surfactant method of preparation of pharmaceutical compositions
GR89300026T GR890300026T1 (en) 1987-04-08 1989-04-12 Natural pulmonary surfactant, method of preparation and pharmaceutical compositions
HU95P/P00628P HU211950A9 (en) 1987-04-08 1995-06-30 Natural pulmonary surfactant, method of preparation and pharmaceutical compositions
HK98106244.4A HK1007103B (en) 1987-04-08 1998-06-24 Natural pulmonary surfactant, method of preparation and pharmaceutical compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8720032A IT1203873B (it) 1987-04-08 1987-04-08 Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e

Publications (2)

Publication Number Publication Date
IT8720032A0 IT8720032A0 (it) 1987-04-08
IT1203873B true IT1203873B (it) 1989-02-23

Family

ID=11163272

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8720032A IT1203873B (it) 1987-04-08 1987-04-08 Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e

Country Status (21)

Country Link
US (1) US5024995A (it)
EP (1) EP0286011B1 (it)
JP (1) JP2700323B2 (it)
AT (1) ATE99949T1 (it)
AU (1) AU619462B2 (it)
CA (1) CA1320440C (it)
DE (2) DE286011T1 (it)
DK (1) DK172921B1 (it)
EG (1) EG19626A (it)
ES (1) ES2004856T3 (it)
FI (1) FI92905C (it)
GR (1) GR890300026T1 (it)
HU (1) HU211950A9 (it)
IE (1) IE61384B1 (it)
IT (1) IT1203873B (it)
MY (1) MY103260A (it)
NO (1) NO174733C (it)
NZ (1) NZ224146A (it)
PH (1) PH25300A (it)
PT (1) PT87188B (it)
ZA (1) ZA882416B (it)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
DE3921954A1 (de) * 1989-07-04 1991-01-17 Thomae Gmbh Dr K Niedrig-viskose, hochkonzentrierte surfactant-suspension
WO1991017766A1 (fr) * 1990-05-18 1991-11-28 Tokyo Tanabe Company Limited Remede contre l'asthme
US5437272A (en) * 1991-05-01 1995-08-01 Alliance Pharmaceutical Corp. Perfluorocarbon associated gas exchange
EP0583358B1 (en) * 1991-05-03 1998-12-02 Alliance Pharmaceutical Corporation Partial liquid breathing of fluorocarbons
DE69226372T2 (de) * 1991-11-14 1999-04-01 Alliance Pharmaceutical Corp., San Diego, Calif. Vorrichtung zur teilweisen flüssigen beatmung mit fluorkohlenwasserstoffen
IT1255967B (it) * 1992-11-27 1995-11-17 Chiesi Farma Spa Procedimento per la purificazione di materiale surfattante polmonare naturale con l'impiego di fluidi supercritici
US5531219A (en) * 1994-11-04 1996-07-02 Alliance Pharmaceutical Corp. Use of liquid fluorocarbons to facilitate pulmonary drug delivery
CO5021218A1 (es) * 1994-12-29 2001-03-27 Ct Nac De Sanidad Agropecuaria Surfactante pulmonar natural porcino
US6129934A (en) * 1995-06-07 2000-10-10 Ony, Inc. Modification of animal lung surfactant for treating respiratory disease due to lung surfactant deficiency or dysfunction
US6172203B1 (en) * 1996-02-07 2001-01-09 Alfredo Adolfo Hager Method for extracting and purifying pulmonary surfactant
WO1997029738A1 (en) * 1996-02-16 1997-08-21 The Administrators Of The Tulane Educational Fund Methods and compositions for treating eustachian tube dysfunction by inhalation
WO2001019392A1 (en) 1999-09-16 2001-03-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
US6676930B2 (en) 1999-11-28 2004-01-13 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
US6156294A (en) 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
DE19957898A1 (de) * 1999-12-01 2001-06-07 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant
DE10018022A1 (de) * 2000-04-12 2001-10-31 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen
ES2346048T3 (es) 2001-10-11 2010-10-08 Nycomed Gmbh Nueva utilizacion de un agente tensioactivo pulmonar.
RU2198670C1 (ru) * 2002-02-19 2003-02-20 ООО "Биосурф" Способ получения сурфактанта из легких крупного рогатого скота
CA2575513C (en) 2004-08-06 2014-09-16 Altana Pharma Ag Composition comprising a pulmonary surfactant and a tnf-derived peptide
US7582312B2 (en) * 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US8337815B2 (en) * 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
JP2008526868A (ja) 2005-01-06 2008-07-24 ディスカバリー ラボラトリーズ，インコーポレイテッド 表面活性剤処置療法
GB2426703B (en) * 2005-05-31 2007-09-19 Malvern Cosmeceutics Ltd Compositions
KR20090060348A (ko) * 2006-09-19 2009-06-11 디스커버리 래보래토리스, 인크. 폐 계면활성제 제제 및 점액 클리어런스 촉진 방법
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
DE102007025898A1 (de) * 2007-06-01 2008-12-04 Matthias W. Dr. Amrein Behandlung von Surfactanten
AU2009324637B2 (en) 2008-12-10 2016-09-08 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
JP2020526585A (ja) * 2017-07-07 2020-08-31 リポバイオメド コーポレイションＬｉｐｏｂｉｏｍｅｄ Ｃｏｒｐｏｒａｔｉｏｎ 火傷及び褥瘡の緩和及び治療用組成物
US11219843B2 (en) * 2019-07-08 2022-01-11 Nik Paya Karen Pharmed Extraction of animal-derived pulmonary surfactants
US20240366682A1 (en) 2021-07-05 2024-11-07 Chiesi Farmaceutici S.P.A. Process for the preparation of a pulmonary surfactant

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55160721A (en) * 1979-06-02 1980-12-13 Tokyo Tanabe Co Ltd Pulmonary surfactant ta-546, its preparation, and remedy for pulmonary hyaline membrane syndrome comprising it as active constituent
US4312860A (en) * 1980-10-24 1982-01-26 Regents Of The University Of California Lung surfactant compositions
JPS5845299A (ja) * 1981-09-10 1983-03-16 東京田辺製薬株式会社 新規な表面活性物質、その製造法及びそれを含有する呼吸窮迫疾候群治療剤
JPS58222022A (ja) * 1982-06-21 1983-12-23 Teijin Ltd 合成肺表面活性剤及びそれを有効成分とする呼吸窮迫症候群治療剤
JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
CS938384A1 (en) * 1983-12-08 1990-08-14 Lachmann Burkhardt Pharmaceutical agent for breathlesness therapy and method of its production
JPS6165821A (ja) * 1984-09-07 1986-04-04 Tokyo Tanabe Co Ltd 合成サ−フアクタント及びそれを有効成分とする肺表面活性物質喪失性無気肺の治療剤
FR2586587B1 (fr) * 1985-08-30 1987-10-23 Adir Nouveaux surfactants artificiels, leur preparation et les compositions pharmaceutiques qui les contiennent.
WO1987006943A1 (en) * 1986-05-06 1987-11-19 Children's Hospital Medical Center Pulmonary hydrophobic surfactant-associated protein of 6,000 daltons molecular weight and multimers thereof

Also Published As

Publication number Publication date
IT8720032A0 (it) 1987-04-08
DE3886970T2 (de) 1994-05-26
JPS6463526A (en) 1989-03-09
MY103260A (en) 1993-05-29
PT87188A (pt) 1988-05-01
DE286011T1 (de) 1989-03-09
DK190088D0 (da) 1988-04-07
AU1433788A (en) 1988-10-13
IE881008L (en) 1988-10-08
EP0286011A3 (en) 1990-02-07
US5024995A (en) 1991-06-18
ATE99949T1 (de) 1994-01-15
FI92905B (fi) 1994-10-14
HU211950A9 (en) 1996-01-29
PT87188B (pt) 1992-07-31
HK1007103A1 (en) 1999-04-01
EG19626A (en) 1995-09-30
NZ224146A (en) 1991-06-25
AU619462B2 (en) 1992-01-30
DE3886970D1 (de) 1994-02-24
EP0286011A2 (en) 1988-10-12
FI881508A0 (fi) 1988-03-30
FI92905C (fi) 1995-01-25
CA1320440C (en) 1993-07-20
NO174733C (no) 1994-06-29
DK190088A (da) 1988-10-09
ES2004856A4 (es) 1989-02-16
PH25300A (en) 1991-04-30
GR890300026T1 (en) 1989-04-12
NO881515L (no) 1988-10-10
ZA882416B (en) 1988-09-28
NO881515D0 (no) 1988-04-07
FI881508L (fi) 1988-10-09
EP0286011B1 (en) 1994-01-12
IE61384B1 (en) 1994-11-02
NO174733B (no) 1994-03-21
DK172921B1 (da) 1999-10-04
JP2700323B2 (ja) 1998-01-21
ES2004856T3 (es) 1994-12-16

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940428