IT1203873B - Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e - Google Patents
Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione eInfo
- Publication number
- IT1203873B IT1203873B IT8720032A IT2003287A IT1203873B IT 1203873 B IT1203873 B IT 1203873B IT 8720032 A IT8720032 A IT 8720032A IT 2003287 A IT2003287 A IT 2003287A IT 1203873 B IT1203873 B IT 1203873B
- Authority
- IT
- Italy
- Prior art keywords
- pulmonary surfactant
- preparation
- pharmaceutical compositions
- natural pulmonary
- surfactant contain
- Prior art date
Links
- 239000003580 lung surfactant Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 abstract 1
- 208000013616 Respiratory Distress Syndrome Diseases 0.000 abstract 1
- 201000000028 adult respiratory distress syndrome Diseases 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/42—Respiratory system, e.g. lungs, bronchi or lung cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0082—Lung surfactant, artificial mucus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Marine Sciences & Fisheries (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Physiology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
Priority Applications (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8720032A IT1203873B (it) | 1987-04-08 | 1987-04-08 | Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e |
| FI881508A FI92905C (fi) | 1987-04-08 | 1988-03-30 | Menetelmä eläinperäisen keuhkojen pinta-aktiivisen aineen valmistamiseksi |
| DE198888105232T DE286011T1 (de) | 1987-04-08 | 1988-03-31 | Natuerliches oberflaechenwirksames lungenpraeparat, verfahren zu seiner herstellung und pharmazeutische zusammensetzungen. |
| EP88105232A EP0286011B1 (en) | 1987-04-08 | 1988-03-31 | Natural pulmonary surfactant, method of preparation and pharmaceutical compositions |
| ES88105232T ES2004856T3 (es) | 1987-04-08 | 1988-03-31 | Agente tensioactivo pulmonar natural, procedimiento de preparacion y composiciones farmaceuticas. |
| DE3886970T DE3886970T2 (de) | 1987-04-08 | 1988-03-31 | Natürliches oberflächenwirksames Lungenpräparat, Verfahren zu seiner Herstellung und pharmazeutische Zusammensetzungen. |
| AT88105232T ATE99949T1 (de) | 1987-04-08 | 1988-03-31 | Natuerliches oberflaechenwirksames lungenpraeparat, verfahren zu seiner herstellung und pharmazeutische zusammensetzungen. |
| US07/177,771 US5024995A (en) | 1987-04-08 | 1988-04-05 | Natural pulmonary surfactant, method of preparation and pharamceutical compositions |
| IE100888A IE61384B1 (en) | 1987-04-08 | 1988-04-06 | Natural pulmonary surfactant, method of preparation and pharmaceutical compositions |
| NZ224146A NZ224146A (en) | 1987-04-08 | 1988-04-06 | Pulmonary surfactant comprised of protein and lipid-fractions |
| PH8836751A PH25300A (en) | 1987-04-08 | 1988-04-06 | Natural pulmonary surfactant, method of preparation and pharmaceutical compositions |
| CA000563558A CA1320440C (en) | 1987-04-08 | 1988-04-07 | Natural pulmonary surfactant, method of preparation and pharmaceutical compositions |
| AU14337/88A AU619462B2 (en) | 1987-04-08 | 1988-04-07 | Natural pulmonary surfactant, method of preparation and pharmaceutical compositions |
| PT87188A PT87188B (pt) | 1987-04-08 | 1988-04-07 | Processo para a preparacao de um tensioactivo pulmonar natural e de composicoes farmaceuticas que o contem |
| ZA882416A ZA882416B (en) | 1987-04-08 | 1988-04-07 | Natural pulmonary surfactant,method of preparation and pharmaceutical compositions |
| JP63086214A JP2700323B2 (ja) | 1987-04-08 | 1988-04-07 | 肺動脈界面活性剤、その調製方法、及び薬剤組成物 |
| NO881515A NO174733C (no) | 1987-04-08 | 1988-04-07 | Fremgangsmåte ved fremstilling av pulmonar surfaktant |
| DK198801900A DK172921B1 (da) | 1987-04-08 | 1988-04-07 | Naturligt, pulmonart, overfladeaktivt middel, fremgangsmåde til fremstilling heraf samt farmaceutiske midler indeholdende d |
| MYPI88000361A MY103260A (en) | 1987-04-08 | 1988-04-08 | Natural pulmonary surfactant, mathod of preparation and pharmaecutical compositions |
| EG20388A EG19626A (en) | 1987-04-08 | 1988-04-10 | Natural pulmonary surfactant method of preparation of pharmaceutical compositions |
| GR89300026T GR890300026T1 (en) | 1987-04-08 | 1989-04-12 | Natural pulmonary surfactant, method of preparation and pharmaceutical compositions |
| HU95P/P00628P HU211950A9 (en) | 1987-04-08 | 1995-06-30 | Natural pulmonary surfactant, method of preparation and pharmaceutical compositions |
| HK98106244A HK1007103A1 (en) | 1987-04-08 | 1998-06-24 | Natural pulmonary surfactant, method of preparation and pharmaceutical compositions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8720032A IT1203873B (it) | 1987-04-08 | 1987-04-08 | Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8720032A0 IT8720032A0 (it) | 1987-04-08 |
| IT1203873B true IT1203873B (it) | 1989-02-23 |
Family
ID=11163272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8720032A IT1203873B (it) | 1987-04-08 | 1987-04-08 | Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5024995A (it) |
| EP (1) | EP0286011B1 (it) |
| JP (1) | JP2700323B2 (it) |
| AT (1) | ATE99949T1 (it) |
| AU (1) | AU619462B2 (it) |
| CA (1) | CA1320440C (it) |
| DE (2) | DE3886970T2 (it) |
| DK (1) | DK172921B1 (it) |
| EG (1) | EG19626A (it) |
| ES (1) | ES2004856T3 (it) |
| FI (1) | FI92905C (it) |
| GR (1) | GR890300026T1 (it) |
| HK (1) | HK1007103A1 (it) |
| HU (1) | HU211950A9 (it) |
| IE (1) | IE61384B1 (it) |
| IT (1) | IT1203873B (it) |
| MY (1) | MY103260A (it) |
| NO (1) | NO174733C (it) |
| NZ (1) | NZ224146A (it) |
| PH (1) | PH25300A (it) |
| PT (1) | PT87188B (it) |
| ZA (1) | ZA882416B (it) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8803713D0 (sv) * | 1988-10-18 | 1988-10-18 | Kabigen Ab | Biologically active lipoprotein and its use |
| DE3921954A1 (de) * | 1989-07-04 | 1991-01-17 | Thomae Gmbh Dr K | Niedrig-viskose, hochkonzentrierte surfactant-suspension |
| AU660612B2 (en) * | 1990-05-18 | 1995-07-06 | Mitsubishi-Tokyo Pharmaceuticals, Inc. | Remedy for asthma |
| US5437272A (en) * | 1991-05-01 | 1995-08-01 | Alliance Pharmaceutical Corp. | Perfluorocarbon associated gas exchange |
| ES2124260T3 (es) * | 1991-05-03 | 1999-02-01 | Alliance Pharma | Respiracion liquida parcial de fluorocarbonos. |
| JPH07503629A (ja) * | 1991-11-14 | 1995-04-20 | アライアンス ファーマシューティカル コーポレイション | フルオロカーボンを用いた部分的液体呼吸法および装置 |
| IT1255967B (it) * | 1992-11-27 | 1995-11-17 | Chiesi Farma Spa | Procedimento per la purificazione di materiale surfattante polmonare naturale con l'impiego di fluidi supercritici |
| US5531219A (en) * | 1994-11-04 | 1996-07-02 | Alliance Pharmaceutical Corp. | Use of liquid fluorocarbons to facilitate pulmonary drug delivery |
| BR9506114A (pt) * | 1994-12-29 | 1997-12-23 | Ctro Nac Sanidad Agropecuaria | Tensoativo pulmonar de origem suína e processo para a sua obtenção |
| US6129934A (en) * | 1995-06-07 | 2000-10-10 | Ony, Inc. | Modification of animal lung surfactant for treating respiratory disease due to lung surfactant deficiency or dysfunction |
| US6172203B1 (en) * | 1996-02-07 | 2001-01-09 | Alfredo Adolfo Hager | Method for extracting and purifying pulmonary surfactant |
| WO1997029738A1 (en) * | 1996-02-16 | 1997-08-21 | The Administrators Of The Tulane Educational Fund | Methods and compositions for treating eustachian tube dysfunction by inhalation |
| US7053176B1 (en) | 1999-09-16 | 2006-05-30 | Altana Pharma Ag | Combination of C1-INH and lung surfactant for the treatment of respiratory disorders |
| US6676930B2 (en) | 1999-11-28 | 2004-01-13 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
| US6156294A (en) | 1999-11-28 | 2000-12-05 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
| DE19957898A1 (de) * | 1999-12-01 | 2001-06-07 | Byk Gulden Lomberg Chem Fab | Neue Verwendung von Lungensurfactant |
| DE10018022A1 (de) * | 2000-04-12 | 2001-10-31 | Byk Gulden Lomberg Chem Fab | Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen |
| ES2346048T3 (es) | 2001-10-11 | 2010-10-08 | Nycomed Gmbh | Nueva utilizacion de un agente tensioactivo pulmonar. |
| RU2198670C1 (ru) * | 2002-02-19 | 2003-02-20 | ООО "Биосурф" | Способ получения сурфактанта из легких крупного рогатого скота |
| CA2575513C (en) | 2004-08-06 | 2014-09-16 | Altana Pharma Ag | Composition comprising a pulmonary surfactant and a tnf-derived peptide |
| US7582312B2 (en) * | 2004-11-15 | 2009-09-01 | Discovery Laboratories, Inc. | Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof |
| US8337815B2 (en) * | 2004-12-23 | 2012-12-25 | Discovery Laboratories, Inc. | Pulmonary surfactant formulations |
| SI1841458T1 (sl) | 2005-01-06 | 2012-04-30 | Discovery Lab Inc | Zdravljenje s predpisanim odmerjanjem surfaktanta za zdravljenje ali preprečevanje bronhopulmonalne displazije |
| GB2426703B (en) * | 2005-05-31 | 2007-09-19 | Malvern Cosmeceutics Ltd | Compositions |
| JP2010503731A (ja) * | 2006-09-19 | 2010-02-04 | ディスカバリー ラボラトリーズ,インコーポレイテッド | 肺サーファクタント製剤および粘液クリアランスの促進方法 |
| US7951781B2 (en) | 2006-11-02 | 2011-05-31 | University Of Iowa Research Foundation | Methods and compositions related to PLUNC surfactant polypeptides |
| DE102007025898A1 (de) * | 2007-06-01 | 2008-12-04 | Matthias W. Dr. Amrein | Behandlung von Surfactanten |
| WO2010068754A2 (en) | 2008-12-10 | 2010-06-17 | Paka Pulmonary Pharmaceuticals, Inc. | Methods and compositions for delivery of medicaments to the lungs |
| WO2019009628A2 (ko) * | 2017-07-07 | 2019-01-10 | 주식회사 리포바이오랩 | 화상 및 욕창의 완화 및 치료용 조성물 |
| US11219843B2 (en) * | 2019-07-08 | 2022-01-11 | Nik Paya Karen Pharmed | Extraction of animal-derived pulmonary surfactants |
| AR126368A1 (es) | 2021-07-05 | 2023-10-11 | Chiesi Farm Spa | Proceso para la preparación de un tensioactivo pulmonar |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55160721A (en) * | 1979-06-02 | 1980-12-13 | Tokyo Tanabe Co Ltd | Pulmonary surfactant ta-546, its preparation, and remedy for pulmonary hyaline membrane syndrome comprising it as active constituent |
| US4312860A (en) * | 1980-10-24 | 1982-01-26 | Regents Of The University Of California | Lung surfactant compositions |
| JPS5845299A (ja) * | 1981-09-10 | 1983-03-16 | 東京田辺製薬株式会社 | 新規な表面活性物質、その製造法及びそれを含有する呼吸窮迫疾候群治療剤 |
| JPS58222022A (ja) * | 1982-06-21 | 1983-12-23 | Teijin Ltd | 合成肺表面活性剤及びそれを有効成分とする呼吸窮迫症候群治療剤 |
| JPS59164724A (ja) * | 1983-03-10 | 1984-09-17 | Tokyo Tanabe Co Ltd | サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤 |
| CS938384A1 (en) * | 1983-12-08 | 1990-08-14 | Lachmann Burkhardt | Pharmaceutical agent for breathlesness therapy and method of its production |
| JPS6165821A (ja) * | 1984-09-07 | 1986-04-04 | Tokyo Tanabe Co Ltd | 合成サ−フアクタント及びそれを有効成分とする肺表面活性物質喪失性無気肺の治療剤 |
| FR2586587B1 (fr) * | 1985-08-30 | 1987-10-23 | Adir | Nouveaux surfactants artificiels, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| EP0273916A4 (en) * | 1986-05-06 | 1989-11-30 | Childrens Hosp Medical Center | LUNG HYDROPHOBES, PROTEIN ASSOCIATED TO A SURFACE ACTIVE MEDIUM OF 6000 DALTON MOLECULAR WEIGHT AND MULTIMEREOUS ITEMS. |
-
1987
- 1987-04-08 IT IT8720032A patent/IT1203873B/it active
-
1988
- 1988-03-30 FI FI881508A patent/FI92905C/fi not_active IP Right Cessation
- 1988-03-31 DE DE3886970T patent/DE3886970T2/de not_active Expired - Lifetime
- 1988-03-31 AT AT88105232T patent/ATE99949T1/de not_active IP Right Cessation
- 1988-03-31 DE DE198888105232T patent/DE286011T1/de active Pending
- 1988-03-31 ES ES88105232T patent/ES2004856T3/es not_active Expired - Lifetime
- 1988-03-31 EP EP88105232A patent/EP0286011B1/en not_active Expired - Lifetime
- 1988-04-05 US US07/177,771 patent/US5024995A/en not_active Expired - Lifetime
- 1988-04-06 NZ NZ224146A patent/NZ224146A/en unknown
- 1988-04-06 IE IE100888A patent/IE61384B1/en not_active IP Right Cessation
- 1988-04-06 PH PH8836751A patent/PH25300A/en unknown
- 1988-04-07 JP JP63086214A patent/JP2700323B2/ja not_active Expired - Lifetime
- 1988-04-07 CA CA000563558A patent/CA1320440C/en not_active Expired - Lifetime
- 1988-04-07 ZA ZA882416A patent/ZA882416B/xx unknown
- 1988-04-07 NO NO881515A patent/NO174733C/no not_active IP Right Cessation
- 1988-04-07 AU AU14337/88A patent/AU619462B2/en not_active Expired
- 1988-04-07 DK DK198801900A patent/DK172921B1/da not_active IP Right Cessation
- 1988-04-07 PT PT87188A patent/PT87188B/pt not_active IP Right Cessation
- 1988-04-08 MY MYPI88000361A patent/MY103260A/en unknown
- 1988-04-10 EG EG20388A patent/EG19626A/xx active
-
1989
- 1989-04-12 GR GR89300026T patent/GR890300026T1/el unknown
-
1995
- 1995-06-30 HU HU95P/P00628P patent/HU211950A9/hu unknown
-
1998
- 1998-06-24 HK HK98106244A patent/HK1007103A1/en not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19940428 |