IT1204314B - Analoghi di tioprostaglandina 7-ossabicicloeptano sostituiti - Google Patents

Analoghi di tioprostaglandina 7-ossabicicloeptano sostituiti

Info

Publication number
IT1204314B
IT1204314B IT20179/86A IT2017986A IT1204314B IT 1204314 B IT1204314 B IT 1204314B IT 20179/86 A IT20179/86 A IT 20179/86A IT 2017986 A IT2017986 A IT 2017986A IT 1204314 B IT1204314 B IT 1204314B
Authority
IT
Italy
Prior art keywords
thioprostaglandin
oxabicycleptane
analogs
replaced
oxabicycleptane replaced
Prior art date
Application number
IT20179/86A
Other languages
English (en)
Other versions
IT8620179A0 (it
Inventor
Steven E Hall
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8620179A0 publication Critical patent/IT8620179A0/it
Application granted granted Critical
Publication of IT1204314B publication Critical patent/IT1204314B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IT20179/86A 1985-04-22 1986-04-22 Analoghi di tioprostaglandina 7-ossabicicloeptano sostituiti IT1204314B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/725,978 US4607049A (en) 1985-04-22 1985-04-22 7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease

Publications (2)

Publication Number Publication Date
IT8620179A0 IT8620179A0 (it) 1986-04-22
IT1204314B true IT1204314B (it) 1989-03-01

Family

ID=24916714

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20179/86A IT1204314B (it) 1985-04-22 1986-04-22 Analoghi di tioprostaglandina 7-ossabicicloeptano sostituiti

Country Status (7)

Country Link
US (1) US4607049A (it)
JP (1) JPS61257987A (it)
CA (1) CA1249289A (it)
DE (1) DE3613406A1 (it)
FR (1) FR2580651B1 (it)
GB (1) GB2173796B (it)
IT (1) IT1204314B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU593316B2 (en) * 1986-02-14 1990-02-08 E.R. Squibb & Sons, Inc. Hydroxamic acids of 7-oxabicycloheptane substituted ethers
EP2147679B1 (en) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions for blood-brain barrier transport
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
CN101594878A (zh) 2006-09-18 2009-12-02 雷普特药品公司 通过给予受体相关蛋白（rap）-缀合物对肝病症的治疗
PL3395372T3 (pl) 2009-02-20 2022-07-25 EnhanX Biopharm Inc. Układ do dostarczania leków na bazie glutationu
CN102458374A (zh) 2009-05-06 2012-05-16 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN113912619B (zh) * 2021-11-26 2022-12-06 沈阳药科大学 五味子中提取分离的倍半萜化合物及其方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
WO1980001381A1 (en) * 1979-01-05 1980-07-10 R Jones Substituted bicyclo (2,2,1) heptanes and hept-2-enes
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
ZA829068B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
US4456616A (en) * 1982-12-27 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
CA1256887A (en) * 1983-03-14 1989-07-04 Steven E. Hall 7-oxabicycloheptane substituted prostaglandin analogs
US4474803A (en) * 1983-03-14 1984-10-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted thio prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction

Also Published As

Publication number Publication date
JPS61257987A (ja) 1986-11-15
CA1249289A (en) 1989-01-24
FR2580651A1 (fr) 1986-10-24
GB2173796B (en) 1988-12-07
GB2173796A (en) 1986-10-22
IT8620179A0 (it) 1986-04-22
US4607049A (en) 1986-08-19
FR2580651B1 (fr) 1988-11-10
GB8609594D0 (en) 1986-05-21
DE3613406A1 (de) 1986-10-23

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