IT1205349B - Determinate pirazolo-chinoline sostituite,procedimento per la loro preparazione,preparati farmaceutici contenenti questi composti e loro impiego terapeutico - Google Patents

Determinate pirazolo-chinoline sostituite,procedimento per la loro preparazione,preparati farmaceutici contenenti questi composti e loro impiego terapeutico

Info

Publication number
IT1205349B
IT1205349B IT49450/83A IT4945083A IT1205349B IT 1205349 B IT1205349 B IT 1205349B IT 49450/83 A IT49450/83 A IT 49450/83A IT 4945083 A IT4945083 A IT 4945083A IT 1205349 B IT1205349 B IT 1205349B
Authority
IT
Italy
Prior art keywords
kinolines
pyrazol
compounds
replaced
procedure
Prior art date
Application number
IT49450/83A
Other languages
English (en)
Other versions
IT8349450A0 (it
Inventor
Naokata Yokoyama
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IT8349450A0 publication Critical patent/IT8349450A0/it
Application granted granted Critical
Publication of IT1205349B publication Critical patent/IT1205349B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT49450/83A 1982-12-08 1983-12-06 Determinate pirazolo-chinoline sostituite,procedimento per la loro preparazione,preparati farmaceutici contenenti questi composti e loro impiego terapeutico IT1205349B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/447,825 US4524146A (en) 1982-12-08 1982-12-08 Certain -2-heterocycle substituted pyrazoloquinolines

Publications (2)

Publication Number Publication Date
IT8349450A0 IT8349450A0 (it) 1983-12-06
IT1205349B true IT1205349B (it) 1989-03-15

Family

ID=23777905

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49450/83A IT1205349B (it) 1982-12-08 1983-12-06 Determinate pirazolo-chinoline sostituite,procedimento per la loro preparazione,preparati farmaceutici contenenti questi composti e loro impiego terapeutico

Country Status (9)

Country Link
US (1) US4524146A (it)
JP (1) JPS59110694A (it)
BE (1) BE898383A (it)
CH (1) CH656127A5 (it)
DE (1) DE3343922A1 (it)
FR (1) FR2537584B1 (it)
GB (1) GB2131801B (it)
IT (1) IT1205349B (it)
NL (1) NL8304224A (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549833B1 (fr) * 1983-07-26 1985-11-08 Roussel Uclaf Derives de la pyrazolo /4,3-c/ cinnolin-3-one, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant et produits intermediaires
US4602014A (en) * 1984-07-09 1986-07-22 Ciba-Geigy Corporation Ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives as benzodiazepine receptor modulators
CA1263651A (en) * 1984-07-09 1989-12-05 Ciba-Geigy Ag Certain ring-fused pyrazolo ¬3,4-d|-pyridin-3-one derivatives
PH21213A (en) * 1984-10-26 1987-08-21 Fujisawa Pharmaceutical Co Benzene- and pyrazole- fused heterocyclic compound and pharmaceutical composition comprising the same
JPS61112075A (ja) * 1984-11-05 1986-05-30 Shionogi & Co Ltd チエニルピラゾロキノリン誘導体
US4591589A (en) * 1985-01-16 1986-05-27 Roussel Uclaf 2-aryl pyrazolo[4,3-c]cinnolin-3-ones
US4758427A (en) * 1985-08-08 1988-07-19 Ciba-Geigy Corporation Enhanced absorption of psychoactive 2-aryl-pyrazolo quinolines as a solid molecular dispersion in polyvinylpyrrolidone
US4831013A (en) * 1986-03-20 1989-05-16 Ciba-Geigy Corporation 2-substituted-e-fused-[1,2,4]triazolo[1,5-c]pyrimidines, pharmaceutical compositions, and uses thereof
US4826854A (en) * 1986-11-25 1989-05-02 Ciba-Geigy Corporation Certain cycloalka-(b)-pyrazolo(3,4-d)-pyridin-3-one derivatives
US5192768A (en) * 1990-09-14 1993-03-09 Kyowa Hakko Kogyo Co., Ltd. Pyrazoloquinoline derivatives
US5334595A (en) * 1992-10-23 1994-08-02 Sterling Winthrop Inc. Pyrazoloquinolones as anticancer agents
ID16283A (id) * 1996-03-20 1997-09-18 Astra Pharma Prod Senyawa yang berguna dibidang farmasi
AU6019900A (en) * 1999-11-24 2001-06-04 Sumika Fine Chemicals Co., Ltd. Anhydrous mirtazapine crystals and process for producing the same
JP2010529144A (ja) * 2007-06-08 2010-08-26 ヘリコン・セラピューティクス・インコーポレーテッド 治療用ピラゾロキノリン尿素誘導体
EP2303890A4 (en) * 2008-06-19 2012-04-11 Progenics Pharm Inc INHIBITORS OF PHOSPHATIDYLINOSITE-3-KINASE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2009079A1 (it) * 1968-05-22 1970-01-30 Sandoz Sa
EP0022078B1 (de) * 1979-06-21 1984-07-25 Ciba-Geigy Ag Pyrazolochinoline, Verfahren zu ihrer Herstellung, und pharmazeutische Präparate enthaltend diese Verbindungen
US4312870A (en) * 1979-06-21 1982-01-26 Ciba-Geigy Corporation Pyrazoloquinolines

Also Published As

Publication number Publication date
GB8332274D0 (en) 1984-01-11
FR2537584A1 (fr) 1984-06-15
NL8304224A (nl) 1984-07-02
GB2131801A (en) 1984-06-27
FR2537584B1 (fr) 1987-01-16
US4524146A (en) 1985-06-18
DE3343922A1 (de) 1984-06-28
IT8349450A0 (it) 1983-12-06
CH656127A5 (de) 1986-06-13
GB2131801B (en) 1986-01-22
JPS59110694A (ja) 1984-06-26
BE898383A (fr) 1984-06-06

Similar Documents

Publication Publication Date Title
IT1179029B (it) Preparati farmaceutici ad attivita antimicrobica e procedimento per la loro preparazione
FI813349A7 (fi) 1-Karboksialkanoyyli-indoliini-2- karboksyylihappoja, menetelmiä niiden valmistamiseksi, näitä yhdisteitsisältäviä farmaseuttisia valmisteita ja niiden terapeuttinen käyttö.
IT1170286B (it) Derivati del labdano, procedimento per la loro preparazione, e composizioni farmaceutiche contenenti derivati del labdano
IT8349450A0 (it) Determinate pirazolo-chinoline sostituite, procedimento per la loro preparazione, preparati farmaceutici contenenti questi composti e loro impiego terapeutico
FI813422A7 (fi) 1-Karboksi-atsa-alkanoyyli- indoliini- karboksyylihappoja, menetelmiä niiden valmistamiseksi, näitä yhdisteitsisältäviä farmaseuttisia valmisteita ja niiden terapeuttinen käyttö.
FI832884A7 (fi) Desoksiuridiini-johdannaiset, niiden valmistusmenetelmät ja käyttö farmaseuttisina aineina.
FI831926A7 (fi) (+)-syanidan-3-olijohdannaisia sisältävät farmaseuttiset valmisteet ja niiden käyttö, uudet substituosubstituoidut (+)-syanidan-3-oli- johdannaiset ja menetelmät niiden vavalmistamiseksi.
IT8248970A0 (it) Derivati xantinici, procedimento per la loro preparazione, composizione farmaceutiche che li contengono e loro impiego terapeutico
IT8348734A0 (it) Impiego di derivati dello zucchero per la profilassi e terapia di infezioni da virus e preparati farmaceutici che contengono tali composti
DE3378208D1 (en) Substituted azabicycloalkanes, their use, pharmaceutical preparations containing these compounds and process for preparing these compounds
IT1201523B (it) Eterociclilfenilfomramidine,processi per la loro preparazione e loro uso farmaceutico
IT1194158B (it) Carbacicline,procedimento per la loro preparazione e loro impiego come medicinali
IT8349055A0 (it) B-osso-l-carbammoil-pirrolpropionitrile, procedimento per la loro produzione, preparati farmaceutici con tenenti questi composti, nonche' il loro impiego terapeutico
IT8220356A0 (it) Guanidino eterociclifenilamidine, processi per la loro preparazione e loro impiego farmaceutico.
IT8321721A0 (it) Composti polienici,procedimento per la loro preparazione e preparati farmaceutici che li contengono
IT1177980B (it) Composti amminometilici, procetimento per produrli, preparati farmaceutici che li contengono
IT8621837A0 (it) Nuovi derivati biciclici del catecolo, procedimento per la loro preparazione e composizioni terapeutiche che li contengono.
FI831927A7 (fi) (+)-syanidan-3-oli- johdannaiset, menetelmät niiden valmistamiseksi, näitä yhdisteitä sisältävät farmasefarmaseuttiset valmisteet ja niiden käyttö.
IT8349163A0 (it) 5h-dibenz/b,f/azepin-5-carbossamidi loro prodotti intermedi, preparati farmaceutici che le contengono, procedimento per produrle e loro impiego
IT1211944B (it) Derivati azolici,procedimento per la loro produzione,preparati farmaceutici che li contengono,e loro impiego
FI813154A7 (fi) 1,5-bis-(1,4-bentsodioksin-2-yyli)-3- atsapentaani-1,5-diolit, menetelmiä niiden valmistamiseksi, näitä yhdiyhdisteitä sisältävät farmaseuttiset valmisteet ja niiden terapeuttinekäyttö.
IT7847545A0 (it) Preparati farmaceutici antidiarroici e procedimento per la loro produzione ed applicazione
IT8348726A0 (it) Composti di amminoimidazolile, procedimenti per la loro produzione e preparati farmaceutici che contengono questi composti
IT8567216A0 (it) Composti pteridinici relativi procedimenti di preparazione e preparati farmaceutici che li contengono
IT1172268B (it) Piperidinoguanidine sostituite,procedimento per la loro preparazione e composizioni farmaceutiche che le contengono