IT1226548B - Benzazepine 3-sostituite ad attivita' farmaceutica - Google Patents

Benzazepine 3-sostituite ad attivita' farmaceutica

Info

Publication number
IT1226548B
IT1226548B IT8821320A IT2132088A IT1226548B IT 1226548 B IT1226548 B IT 1226548B IT 8821320 A IT8821320 A IT 8821320A IT 2132088 A IT2132088 A IT 2132088A IT 1226548 B IT1226548 B IT 1226548B
Authority
IT
Italy
Prior art keywords
benzazepine
substituted
pharmaceutical activities
activities
pharmaceutical
Prior art date
Application number
IT8821320A
Other languages
English (en)
Other versions
IT8821320A0 (it
Inventor
Jagabandhu Das
David M Floyd
Original Assignee
E R Squibb & Sons Inc P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E R Squibb & Sons Inc P filed Critical E R Squibb & Sons Inc P
Publication of IT8821320A0 publication Critical patent/IT8821320A0/it
Application granted granted Critical
Publication of IT1226548B publication Critical patent/IT1226548B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT8821320A 1987-07-17 1988-07-11 Benzazepine 3-sostituite ad attivita' farmaceutica IT1226548B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/074,734 US4767756A (en) 1987-07-17 1987-07-17 3-substituted benzazepines

Publications (2)

Publication Number Publication Date
IT8821320A0 IT8821320A0 (it) 1988-07-11
IT1226548B true IT1226548B (it) 1991-01-24

Family

ID=22121360

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8821320A IT1226548B (it) 1987-07-17 1988-07-11 Benzazepine 3-sostituite ad attivita' farmaceutica

Country Status (7)

Country Link
US (1) US4767756A (it)
JP (1) JPS6438074A (it)
CA (1) CA1300621C (it)
DE (1) DE3823919A1 (it)
FR (1) FR2618150B1 (it)
GB (1) GB2206884B (it)
IT (1) IT1226548B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0322779A3 (en) * 1987-12-29 1991-05-08 Yoshitomi Pharmaceutical Industries, Ltd. Benzolactam compounds and pharmaceutical uses thereof
US5559017A (en) * 1989-08-09 1996-09-24 E. R. Squibb & Sons, Inc. Microbial reduction of benzazepines and benzothiazepine derivatives
US5093988A (en) * 1991-01-24 1992-03-10 Kohler Co. Method for attaching a flexible connector
TW213901B (it) * 1992-01-27 1993-10-01 Pfizer
US5484917A (en) * 1993-06-16 1996-01-16 Pfizer Inc. Substituted tetrahydrobenzazepinones
RU2124503C1 (ru) * 1992-05-18 1999-01-10 И.Р.Сквибб энд Санз, Инк. Гетероциклические азотсодержащие производные карбоновой кислоты, способ их получения и фармацевтическая композиция
ES2097688A1 (es) * 1993-07-14 1997-04-01 Pfizer Hexahidroazepinonas y tetrahidrobenzazepinonas sustituidas.
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
CA2789262C (en) 2005-04-28 2016-10-04 Proteus Digital Health, Inc. Pharma-informatics system
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
TR201908314T4 (tr) 2009-02-20 2019-06-21 2 Bbb Medicines B V Glutatyon bazlı ilaç dağıtım sistemi.
KR101909711B1 (ko) 2009-05-06 2018-12-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3312691A (en) * 1963-08-23 1967-04-04 Ciba Geigy Corp 2, 3, 4, 5-tetrahydro-1-benzazepin-2-ones
US3330823A (en) * 1964-12-16 1967-07-11 Squibb & Sons Inc N-amino-loweralkylene-benzo-lactams
US3395150A (en) * 1965-02-26 1968-07-30 Squibb & Sons Inc Benzothiazepine carboxamides and derivatives thereof
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
CA1271747C (en) * 1985-06-12 1990-07-17 BENZAZEPINE DERIVATIVES

Also Published As

Publication number Publication date
IT8821320A0 (it) 1988-07-11
US4767756A (en) 1988-08-30
GB2206884A (en) 1989-01-18
GB2206884B (en) 1991-04-17
FR2618150A1 (fr) 1989-01-20
DE3823919A1 (de) 1989-01-26
JPS6438074A (en) 1989-02-08
GB8816932D0 (en) 1988-08-17
FR2618150B1 (fr) 1994-08-12
CA1300621C (en) 1992-05-12

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950729