IT1226742B - Piperidine pontate, loro preparazione e loro impiego come medicamenti. - Google Patents

Piperidine pontate, loro preparazione e loro impiego come medicamenti.

Info

Publication number: IT1226742B
Authority: IT; Italy
Prior art keywords: piperidins; medications; bridge; preparation; bridge piperidins
Prior art date: 1987-08-20

Application number

IT8821719A

Other languages

English (en)

Italian (it)

Other versions

IT8821719A0 (it

Inventor

Laszlo Revesz

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-08-20

Filing date

1988-08-19

Publication date

1991-02-05

1988-08-19 Application filed by Sandoz Ag filed Critical Sandoz Ag

1988-08-19 Publication of IT8821719A0 publication Critical patent/IT8821719A0/it

1991-02-05 Application granted granted Critical

1991-02-05 Publication of IT1226742B publication Critical patent/IT1226742B/it

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IT8821719A 1987-08-20 1988-08-19 Piperidine pontate, loro preparazione e loro impiego come medicamenti. IT1226742B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3727733		1987-08-20

Publications (2)

Publication Number	Publication Date
IT8821719A0 IT8821719A0 (it)	1988-08-19
IT1226742B true IT1226742B (it)	1991-02-05

Family

ID=6334102

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT8821719A IT1226742B (it)	1987-08-20	1988-08-19	Piperidine pontate, loro preparazione e loro impiego come medicamenti.

Country Status (17)

Country	Link
JP (1)	JPS6471874A (da)
KR (1)	KR950000509B1 (da)
AU (1)	AU2110588A (da)
DE (1)	DE3827253A1 (da)
DK (1)	DK465188A (da)
FI (1)	FI883838A7 (da)
FR (1)	FR2619565A1 (da)
GB (1)	GB2208862A (da)
GR (1)	GR880100538A (da)
IL (1)	IL87489A0 (da)
IT (1)	IT1226742B (da)
LU (1)	LU87314A1 (da)
NL (1)	NL8802059A (da)
PL (1)	PL274318A1 (da)
PT (1)	PT88296B (da)
SE (1)	SE8802926L (da)
ZA (1)	ZA886180B (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR920700034A (ko)	1989-04-21	1992-02-19	예안 크라메르·한스 루돌프 하우스	5-ht₃수용체 길항제의 치료용도
GB2236751B (en) *	1989-10-14	1993-04-28	Wyeth John & Brother Ltd	Heterocyclic compounds
US5225419A (en) *	1989-10-14	1993-07-06	John Wyeth & Brother, Limited	Certain 1,8-ethano or propano-1,4-dihydro-4-oxo-quinoline-3-carboxamides and derivatives thereof
US5187166A (en) *	1990-07-31	1993-02-16	Nisshin Flour Milling Co., Ltd.	Azabicyclo derivatives and their use as antiemetics
US5143923B1 (en) *	1991-04-29	1993-11-02	Hoechst-Roussel Pharmaceuticals Incorporated	Benzoisothiazole-and benzisoxazole-3-carboxamides
US5225412A (en) *	1991-04-29	1993-07-06	Hoechst-Roussel Pharmaceuticals Incorporated	Benzoisothiazole-and benzisoxazole-3-carboxamides
DE4126999A1 (de) *	1991-08-16	1993-02-18	Basf Ag	Herbizide mittel, enthaltend 3-aminobenzo(b)thiophene als antidots
DE10164139A1 (de)	2001-12-27	2003-07-10	Bayer Ag	2-Heteroarylcarbonsäureamide
US8354427B2 (en)	2004-06-24	2013-01-15	Vertex Pharmaceutical Incorporated	Modulators of ATP-binding cassette transporters
CN101891680B (zh)	2004-06-24	2014-10-29	沃泰克斯药物股份有限公司	Atp-结合弹夹转运蛋白的调控剂
US7592461B2 (en)	2005-12-21	2009-09-22	Bristol-Myers Squibb Company	Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
DK3219705T3 (da)	2005-12-28	2020-04-14	Vertex Pharma	Farmaceutiske sammensætninger af den amorfe form af n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinolin-3-carboxamid
WO2008005910A2 (en)	2006-07-06	2008-01-10	Bristol-Myers Squibb Company	Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors
AU2008210455A1 (en)	2007-01-31	2008-08-07	Vertex Pharmaceuticals Incorporated	2-aminopyridine derivatives useful as kinase inhibitors
CN102131809A (zh)	2008-07-23	2011-07-20	沃泰克斯药物股份有限公司	三环吡唑并吡啶激酶抑制剂
AU2009274011B2 (en)	2008-07-23	2014-12-18	Vertex Pharmaceuticals Incorporated	Pyrazolopyridine kinase inhibitors
US8569337B2 (en)	2008-07-23	2013-10-29	Vertex Pharmaceuticals Incorporated	Tri-cyclic pyrazolopyridine kinase inhibitors
JP2011530527A (ja)	2008-08-06	2011-12-22	バーテックスファーマシューティカルズインコーポレイテッド	アミノピリジンキナーゼ阻害剤
US20100074949A1 (en)	2008-08-13	2010-03-25	William Rowe	Pharmaceutical composition and administration thereof
US12458635B2 (en)	2008-08-13	2025-11-04	Vertex Pharmaceuticals Incorporated	Pharmaceutical composition and administrations thereof
CA2894860C (en)	2008-11-19	2018-11-06	Gerhard Koenig	Treatment of cognitive disorders with (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof
KR101727762B1 (ko)	2009-03-20	2017-04-17	버텍스 파마슈티칼스 인코포레이티드	낭성 섬유증 막횡단 전도도 조절자의 조정자의 제조 방법
MX2011011653A (es)	2009-05-06	2012-01-20	Vertex Pharma	Pirazolopiridinas.
AU2011209649A1 (en)	2010-01-27	2012-08-09	Vertex Pharmaceuticals Incorporated	Pyrazolopyrazine kinase inhibitors
CN102858769A (zh)	2010-01-27	2013-01-02	沃泰克斯药物股份有限公司	吡唑并吡啶激酶抑制剂
JP2013518114A (ja)	2010-01-27	2013-05-20	バーテックスファーマシューティカルズインコーポレイテッド	ピラゾロピリミジンキナーゼ阻害剤
MX357676B (es)	2010-05-17	2018-07-18	Forum Pharmaceuticals Inc	Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin- 3-il)benzo[b]tiofeno-2-carboxamida monohidratado.
US8802700B2 (en)	2010-12-10	2014-08-12	Vertex Pharmaceuticals Incorporated	Modulators of ATP-Binding Cassette transporters
JP2015511583A (ja)	2012-02-27	2015-04-20	バーテックスファーマシューティカルズインコーポレイテッドＶｅｒｔｅｘＰｈａｒｍａｃｅｕｔｉｃａｌｓＩｎｃｏｒｐｏｒａｔｅｄ	薬学的組成物およびその投与
EP3666272A1 (en)	2012-05-08	2020-06-17	Forum Pharmaceuticals Inc.	Use of encenicline in the treatment of cognitive impairment, alzheimer's disease, memory deficit
CN107250113B (zh)	2014-10-07	2019-03-29	弗特克斯药品有限公司	囊性纤维化跨膜传导调节蛋白的调节剂的共晶
GB201511382D0 (en)	2015-06-29	2015-08-12	Imp Innovations Ltd	Novel compounds and their use in therapy
EP4045485A1 (en)	2019-10-18	2022-08-24	The Regents Of The University Of California	3-phenylsulphonyl-quinoline derivatives as agents for treating pathogenic blood vessels disorders
US12590298B2 (en)	2019-10-18	2026-03-31	The Regents Of The University Of California	Ex vivo tumor angiogenesis model
WO2024052684A1 (en)	2022-09-09	2024-03-14	MyricX Pharma Limited	Antibody drug conjugate comprising nmt inhibitor and its use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0095262B1 (en) *	1982-05-11	1986-12-03	Beecham Group Plc	Azabicycloalkane derivatives, their preparation and medicaments containing them
FR2531083B1 (fr) *	1982-06-29	1986-11-28	Sandoz Sa	Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
DE3429830A1 (de) *	1983-08-26	1985-03-07	Sandoz-Patent-GmbH, 7850 Lörrach	Automatische carbonsaeure- und sulfonsaeureester oder -amide

1988
- 1988-08-11 DE DE3827253A patent/DE3827253A1/de not_active Withdrawn
- 1988-08-16 LU LU87314A patent/LU87314A1/fr unknown
- 1988-08-16 FR FR8810975A patent/FR2619565A1/fr not_active Withdrawn
- 1988-08-16 GB GB8819438A patent/GB2208862A/en not_active Withdrawn
- 1988-08-18 IL IL87489A patent/IL87489A0/xx unknown
- 1988-08-18 DK DK465188A patent/DK465188A/da not_active Application Discontinuation
- 1988-08-18 SE SE8802926A patent/SE8802926L/xx unknown
- 1988-08-18 AU AU21105/88A patent/AU2110588A/en not_active Abandoned
- 1988-08-18 PT PT88296A patent/PT88296B/pt not_active IP Right Cessation
- 1988-08-18 FI FI883838A patent/FI883838A7/fi not_active IP Right Cessation
- 1988-08-19 IT IT8821719A patent/IT1226742B/it active
- 1988-08-19 PL PL27431888A patent/PL274318A1/xx unknown
- 1988-08-19 KR KR1019880010957A patent/KR950000509B1/ko not_active Expired - Lifetime
- 1988-08-19 NL NL8802059A patent/NL8802059A/nl not_active Application Discontinuation
- 1988-08-19 ZA ZA886180A patent/ZA886180B/xx unknown
- 1988-08-19 JP JP63207189A patent/JPS6471874A/ja active Pending
- 1988-08-22 GR GR880100538A patent/GR880100538A/el unknown

Also Published As

Publication number	Publication date
JPS6471874A (en)	1989-03-16
FI883838L (fi)	1989-02-21
GR880100538A (el)	1989-05-25
AU2110588A (en)	1989-03-23
IT8821719A0 (it)	1988-08-19
KR950000509B1 (ko)	1995-01-24
DK465188A (da)	1989-02-21
ZA886180B (en)	1990-07-25
SE8802926L (sv)	1989-02-21
FI883838A0 (fi)	1988-08-18
NL8802059A (nl)	1989-03-16
PL274318A1 (en)	1989-04-17
DK465188D0 (da)	1988-08-18
KR890003679A (ko)	1989-04-17
LU87314A1 (fr)	1989-03-08
GB8819438D0 (en)	1988-09-21
PT88296A (pt)	1989-06-30
SE8802926D0 (sv)	1988-08-18
IL87489A0 (en)	1989-01-31
PT88296B (pt)	1995-03-31
FR2619565A1 (fr)	1989-02-24
GB2208862A (en)	1989-04-19
DE3827253A1 (de)	1989-03-02
FI883838A7 (fi)	1989-02-21

Publication	Publication Date	Title
IT8821719A0 (it)	1988-08-19	Piperidine pontate, loro preparazione e loro impiego come medicamenti.
IT1219940B (it)	1990-05-24	Benzo-b-pirani e piranopiridone,loro preparazione e loro impiego come medicamenti
FI903382A0 (fi)	1990-07-04	Topiskt anbringbara farmaceutiska preparat.
NO880410D0 (no)	1988-01-29	Oralt preparat.
IT1219811B (it)	1990-05-24	Derivati peptidici,loro preparazione e loro impiego come medicamenti
IT1200092B (it)	1989-01-05	Derivati amminopropossi, loro preparazione e loro impiego come medicamenti
IT1189229B (it)	1988-01-28	Polipeptedi,loro preparazione e loro impiego come medicamenti
FI900010L (fi)	1990-01-02	Anordning vid kapell, i synnerhet fordonskapell.
FI873630A0 (fi)	1987-08-21	Stabilt farmaceutiskt preparat.
FI884050A7 (fi)	1989-03-05	Anordning foer ytbelaeggning av en runt om en motvals foerd materialbana.
FI883371A7 (fi)	1989-02-19	Foerfarande foer behandling av brandrester vid en foerbraenningsanlaeggning, saerskilt vid en sopfoerbraenningsanlaeggning.
IT8848259A0 (it)	1988-08-02	1,4-diidropiridine, loro procedimento di preparazione e loro applicazione come medicamenti
IT1219542B (it)	1990-05-18	Derivati pepticidi,loro preparazione e loro impiego come medicamenti
DE3854077D1 (de)	1995-08-03	Piperidin-Derivate.
DE3866077D1 (de)	1991-12-12	4-aryl-5-carbamoyl-1,4-dihydropyridine.
FI883673A0 (fi)	1988-08-05	Farmaceutiska kompositioner.
IT1214648B (it)	1990-01-18	8 alfa-acilamminoergoline,loro preparazione e loro impiego come medicamenti
FI874382A0 (fi)	1987-10-06	Farmaceutiska preparat.
IT1203816B (it)	1989-02-23	Disaccaridi,loro preparazione e loro impiego come medicamenti
IT1200095B (it)	1989-01-05	Composti maftalenici, loro preparazione e loro impiego come medicamenti
FI852221A7 (fi)	1985-12-08	Sydän-verisuonilääkkeinä käytettäviä dihydropyridiinejä.
IT1216783B (it)	1990-03-14	8 alfa acilamminoergoline ,loro preparazione e loro impiego come medicamenti
FI883747A0 (fi)	1988-08-12	Topiskt anvaendbara farmaceutiska preparat.
IT1235166B (it)	1992-06-22	Peptidi contenenti silicio, loro preparazione e loro impiego come medicamenti
IT1199949B (it)	1989-01-05	Diazepinoindoli,loro preparazione e loro impiego come medicamenti