IT1231488B - Soluzione acquosa farmaceutica tamponata a ph 4,5 per uso oftalmico contenente ibopamina e idrossipropilmetilcellulosa - Google Patents

Soluzione acquosa farmaceutica tamponata a ph 4,5 per uso oftalmico contenente ibopamina e idrossipropilmetilcellulosa

Info

Publication number: IT1231488B
Authority: IT; Italy
Prior art keywords: hydroxypropylmethylcellulose; water solution; use containing; ophthalmic use; solution buffered
Prior art date: 1988-11-09

Application number

IT8822558A

Other languages

English (en)

Other versions

IT8822558A0 (it

Inventor

Federico Stroppolo

Annibale Gazzaniga

Cesare Casagrande

Original Assignee

Zambon Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-11-09

Filing date

1988-11-09

Publication date

1991-12-07

1988-11-09 Application filed by Zambon Spa filed Critical Zambon Spa

1988-11-09 Publication of IT8822558A0 publication Critical patent/IT8822558A0/it

1988-11-09 Priority to IT8822558A priority Critical patent/IT1231488B/it

1989-10-13 Priority to KR1019900701461A priority patent/KR0137647B1/ko

1989-10-30 Priority to IL9214689A priority patent/IL92146A/en

1989-10-31 Priority to AT89913132T priority patent/ATE101037T1/de

1989-10-31 Priority to DE68912947T priority patent/DE68912947T2/de

1989-10-31 Priority to PCT/EP1989/001304 priority patent/WO1990004964A1/en

1989-10-31 Priority to EP89913132A priority patent/EP0442958B1/en

1989-10-31 Priority to AU46297/89A priority patent/AU628114B2/en

1989-10-31 Priority to JP2500034A priority patent/JP2842689B2/ja

1989-11-01 Priority to ZA898325A priority patent/ZA898325B/xx

1989-11-07 Priority to GR890100737A priority patent/GR1002474B/el

1989-11-07 Priority to ES8903769A priority patent/ES2018939A6/es

1989-11-08 Priority to CA002002552A priority patent/CA2002552C/en

1989-11-08 Priority to IE359689A priority patent/IE62756B1/en

1991-04-29 Priority to DK199100780A priority patent/DK175270B1/da

1991-05-02 Priority to FI912131A priority patent/FI94389C/fi

1991-12-07 Application granted granted Critical

1991-12-07 Publication of IT1231488B publication Critical patent/IT1231488B/it

Links

WDKXLLJDNUBYCY-UHFFFAOYSA-N ibopamine Chemical compound CNCCC1=CC=C(OC(=O)C(C)C)C(OC(=O)C(C)C)=C1 WDKXLLJDNUBYCY-UHFFFAOYSA-N 0.000 title 2
UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 title 1
235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 title 1
229920003088 hydroxypropyl methyl cellulose Polymers 0.000 title 1
239000001866 hydroxypropyl methyl cellulose Substances 0.000 title 1
229960004370 ibopamine Drugs 0.000 title 1
239000008238 pharmaceutical water Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Emergency Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IT8822558A 1988-11-09 1988-11-09 Soluzione acquosa farmaceutica tamponata a ph 4,5 per uso oftalmico contenente ibopamina e idrossipropilmetilcellulosa IT1231488B (it)

Priority Applications (16)

Application Number	Priority Date	Filing Date	Title
IT8822558A IT1231488B (it)	1988-11-09	1988-11-09	Soluzione acquosa farmaceutica tamponata a ph 4,5 per uso oftalmico contenente ibopamina e idrossipropilmetilcellulosa
KR1019900701461A KR0137647B1 (ko)	1988-11-09	1989-10-13	이보파민의 수용성 산 부가 염을 포함하는 안과용 약학 조성물
IL9214689A IL92146A (en)	1988-11-09	1989-10-30	Aqueous solution of water-soluble adsorption salt of ibopamine for ophthalmic use
JP2500034A JP2842689B2 (ja)	1988-11-09	1989-10-31	水溶性イボパミン酸付加塩を含有する眼薬
DE68912947T DE68912947T2 (de)	1988-11-09	1989-10-31	Ein lösliches ibopamin-salz enthaltende augenarzneizubereitung.
PCT/EP1989/001304 WO1990004964A1 (en)	1988-11-09	1989-10-31	Pharmaceutical composition for ophthalmic use comprising a water soluble acid addition salt of ibopamine
EP89913132A EP0442958B1 (en)	1988-11-09	1989-10-31	Pharmaceutical composition for ophthalmic use comprising a water soluble acid addition salt of ibopamine
AU46297/89A AU628114B2 (en)	1988-11-09	1989-10-31	Pharmaceutical composition for ophthalmic use comprising a water soluble acid addition salt of ibopamine
AT89913132T ATE101037T1 (de)	1988-11-09	1989-10-31	Ein loesliches ibopamin-salz enthaltende augenarzneizubereitung.
ZA898325A ZA898325B (en)	1988-11-09	1989-11-01	Pharmaceutical aqueous solution for ophthalmic use comprising a water soluble acid addition salt of ibopamine
GR890100737A GR1002474B (el)	1988-11-09	1989-11-07	Μεθοδος παρασκευης μιας φαρμακευτικης συνθεσεως δι'οφθαλμικη χρησιν η οποια περιλαμβανει ενα υδατοδιαλυτο αλας δια προσθηκης οξεος ιμποπαμινης.
ES8903769A ES2018939A6 (es)	1988-11-09	1989-11-07	Procedimiento de preparacion de una composicion farmaceutica para uso oftalmico.
CA002002552A CA2002552C (en)	1988-11-09	1989-11-08	Pharmaceutical aqueous solution for ophthalmic use comprising a water solube pharmaceutically acceptable acid addition salt of ibopamine
IE359689A IE62756B1 (en)	1988-11-09	1989-11-08	Pharmaceutical aqueous solution for ophthalmic use comprising a water soluble pharmaceutically acceptable acid addition salt of ibopamine
DK199100780A DK175270B1 (da)	1988-11-09	1991-04-29	Farmaceutisk præparat til opthalmisk anvendelse om fattende et vandoplöseligt syreadditionssalt af ibopamin
FI912131A FI94389C (fi)	1988-11-09	1991-05-02	Menetelmä silmään käytettävän farmaseuttisen vesiliuoksen valmistamiseksi, joka sisältää ibopamiinin vesiliukoista happoadditiosuolaa

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT8822558A IT1231488B (it)	1988-11-09	1988-11-09	Soluzione acquosa farmaceutica tamponata a ph 4,5 per uso oftalmico contenente ibopamina e idrossipropilmetilcellulosa

Publications (2)

Publication Number	Publication Date
IT8822558A0 IT8822558A0 (it)	1988-11-09
IT1231488B true IT1231488B (it)	1991-12-07

Family

ID=11197818

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT8822558A IT1231488B (it)	1988-11-09	1988-11-09	Soluzione acquosa farmaceutica tamponata a ph 4,5 per uso oftalmico contenente ibopamina e idrossipropilmetilcellulosa

Country Status (15)

Country	Link
EP (1)	EP0442958B1 (it)
JP (1)	JP2842689B2 (it)
KR (1)	KR0137647B1 (it)
AU (1)	AU628114B2 (it)
CA (1)	CA2002552C (it)
DE (1)	DE68912947T2 (it)
DK (1)	DK175270B1 (it)
ES (1)	ES2018939A6 (it)
FI (1)	FI94389C (it)
GR (1)	GR1002474B (it)
IE (1)	IE62756B1 (it)
IL (1)	IL92146A (it)
IT (1)	IT1231488B (it)
WO (1)	WO1990004964A1 (it)
ZA (1)	ZA898325B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU6973094A (en) *	1993-06-24	1995-01-17	Leiras Oy	Composition for ophthalmic use
ITMI20040146A1 (it) *	2004-01-30	2004-04-30	Acraf	Ibopamina maleato metodo per prepararlo e composizioni farmaceutiche che lo comprendono
WO2022099195A1 (en) *	2020-11-09	2022-05-12	The Board Of Trustees Of The Leland Stanford Junior University	Ophthalmic formulation containing a dopaminergic prodrug that may be combined with one or more agents
WO2025181000A1 (en) *	2024-02-26	2025-09-04	Emagine Sa	Composition for the treatment of keratoconus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US421470A (en) *		1890-02-18		alden
IT1178800B (it) *	1984-12-27	1987-09-16	Simes	Composizioni farmaceutiche e loro uso come midriatici

1988
- 1988-11-09 IT IT8822558A patent/IT1231488B/it active
1989
- 1989-10-13 KR KR1019900701461A patent/KR0137647B1/ko not_active Expired - Fee Related
- 1989-10-30 IL IL9214689A patent/IL92146A/en unknown
- 1989-10-31 WO PCT/EP1989/001304 patent/WO1990004964A1/en not_active Ceased
- 1989-10-31 JP JP2500034A patent/JP2842689B2/ja not_active Expired - Lifetime
- 1989-10-31 AU AU46297/89A patent/AU628114B2/en not_active Expired
- 1989-10-31 EP EP89913132A patent/EP0442958B1/en not_active Expired - Lifetime
- 1989-10-31 DE DE68912947T patent/DE68912947T2/de not_active Expired - Lifetime
- 1989-11-01 ZA ZA898325A patent/ZA898325B/xx unknown
- 1989-11-07 ES ES8903769A patent/ES2018939A6/es not_active Expired - Fee Related
- 1989-11-07 GR GR890100737A patent/GR1002474B/el not_active IP Right Cessation
- 1989-11-08 CA CA002002552A patent/CA2002552C/en not_active Expired - Lifetime
- 1989-11-08 IE IE359689A patent/IE62756B1/en not_active IP Right Cessation
1991
- 1991-04-29 DK DK199100780A patent/DK175270B1/da not_active IP Right Cessation
- 1991-05-02 FI FI912131A patent/FI94389C/fi active

Also Published As

Publication number	Publication date
ZA898325B (en)	1990-09-26
GR890100737A (el)	1990-12-31
IL92146A (en)	1994-06-24
DE68912947D1 (de)	1994-03-17
EP0442958A1 (en)	1991-08-28
FI94389B (fi)	1995-05-31
DK78091D0 (da)	1991-04-29
DE68912947T2 (de)	1994-08-25
FI912131A0 (fi)	1991-05-02
IE893596L (en)	1990-05-09
WO1990004964A1 (en)	1990-05-17
CA2002552C (en)	1999-12-07
DK175270B1 (da)	2004-08-02
IE62756B1 (en)	1995-02-22
EP0442958B1 (en)	1994-02-02
JPH04501563A (ja)	1992-03-19
FI94389C (fi)	1995-09-11
KR900701263A (ko)	1990-12-01
ES2018939A6 (es)	1991-05-16
IL92146A0 (en)	1990-07-12
AU628114B2 (en)	1992-09-10
GR1002474B (el)	1996-11-26
DK78091A (da)	1991-04-29
JP2842689B2 (ja)	1999-01-06
KR0137647B1 (ko)	1998-05-15
CA2002552A1 (en)	1990-05-09
AU4629789A (en)	1990-05-28
IT8822558A0 (it)	1988-11-09

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19951123

Publication	Publication Date	Title
DE68916973D1 (de)	1994-08-25	Anwendungssystem für arzneimittel enthaltende mikroemulsionen.
BE1003835B5 (fr)	1992-11-10	Dispositif d'administration.
NO894079L (no)	1990-04-17	Begroingshindrende belegg.
DE3884181D1 (de)	1993-10-21	Ophthalmologisches Gerät.
FI894573L (fi)	1990-03-28	Belaeggningsfoerfarande.
FI890611L (fi)	1989-08-11	3'-deamino-4'-deoxi-4'-amino -antracykliner.
ES1006334Y (es)	1989-08-01	Recipiente de uso infantil.
DE68911671D1 (de)	1994-02-03	Flüssigkeitsverabreichungsstange.
DE68912978D1 (de)	1994-03-24	Abnützungsresistente Prothesenvorrichtung.
KR900700425A (ko)	1990-08-13	2,3-디플루오로페놀 유도체
IT1231488B (it)	1991-12-07	Soluzione acquosa farmaceutica tamponata a ph 4,5 per uso oftalmico contenente ibopamina e idrossipropilmetilcellulosa
ATE77367T1 (de)	1992-07-15	5-substituierte ornithin-derivate.
IT8819791A0 (it)	1988-03-16	Peptidi ad attivita' farmaceutica.
DE68915203D1 (de)	1994-06-16	Pharmazeutische Mischungen.
DE68920608D1 (de)	1995-03-02	Autoklav.
NO883319D0 (no)	1988-07-27	Laaseanordning for stolseter.
NO891480L (no)	1989-10-24	N-substituerte n-aminopyrroler.
DE58903154D1 (de)	1993-02-11	2,2-difluorcyclopropyl-derivate.
DE68921230D1 (de)	1995-03-30	Optisch-aktive Pyridylethanol-Derivate.
DE58905160D1 (de)	1993-09-09	Pharmazeutische zubereitung.
FI893366L (fi)	1990-01-13	4-piperidylmetyl-2,3-dihydro-1h -isoindol- och 2,3,4,5-tetrahydro-1h-bensasepinderivat, deras framstaellning och terapeutiska anvaendning.
IT8904811A0 (it)	1989-03-07	Supporto a perno per un'antina parasole.
DE58905428D1 (de)	1993-10-07	Schwingungsarmes Strömungsventil.
DE68902734D1 (de)	1992-10-08	Elektroviskose fluessigkeit.
IT8820245A0 (it)	1988-04-19	Palmitoil_fruttosio_1,6_difosfato, suo uso terapeutico e relativi metodi di preparazione.