IT1235032B - Composizione farmaceutica comprendente inosina,acido p-acetammidobenzoico e zidovudina per il trattamento dell'aids e sindromi correlate - Google Patents

Composizione farmaceutica comprendente inosina,acido p-acetammidobenzoico e zidovudina per il trattamento dell'aids e sindromi correlate

Info

Publication number: IT1235032B
Authority: IT; Italy
Prior art keywords: zidovudine; compsn; azt; dosage; low
Prior art date: 1988-10-12

Application number

IT8848444A

Other languages

English (en)

Other versions

IT8848444A0 (it

Inventor

Claudio De Simone

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-12

Filing date

1988-10-12

Publication date

1992-06-17

1988-10-12 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

1988-10-12 Priority to IT8848444A priority Critical patent/IT1235032B/it

1988-10-12 Publication of IT8848444A0 publication Critical patent/IT8848444A0/it

1989-09-27 Priority to EP89830422A priority patent/EP0362162B1/en

1989-09-27 Priority to ES198989830422T priority patent/ES2038847T3/es

1989-09-27 Priority to DE8989830422T priority patent/DE68900926D1/de

1989-09-27 Priority to JP1251704A priority patent/JPH02142733A/ja

1989-09-27 Priority to AT89830422T priority patent/ATE72981T1/de

1990-10-09 Priority to US07/595,758 priority patent/US5108993A/en

1992-04-20 Priority to GR920400777T priority patent/GR3004419T3/el

1992-06-17 Application granted granted Critical

1992-06-17 Publication of IT1235032B publication Critical patent/IT1235032B/it

Links

HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 title abstract 6
229960002555 zidovudine Drugs 0.000 title abstract 6
208000030507 AIDS Diseases 0.000 title abstract 2
QCXJEYYXVJIFCE-UHFFFAOYSA-N 4-acetamidobenzoic acid Chemical compound CC(=O)NC1=CC=C(C(O)=O)C=C1 QCXJEYYXVJIFCE-UHFFFAOYSA-N 0.000 abstract 3
YLDCUKJMEKGGFI-QCSRICIXSA-N 4-acetamidobenzoic acid;9-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purin-6-one;1-(dimethylamino)propan-2-ol Chemical compound CC(O)CN(C)C.CC(O)CN(C)C.CC(O)CN(C)C.CC(=O)NC1=CC=C(C(O)=O)C=C1.CC(=O)NC1=CC=C(C(O)=O)C=C1.CC(=O)NC1=CC=C(C(O)=O)C=C1.O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(NC=NC2=O)=C2N=C1 YLDCUKJMEKGGFI-QCSRICIXSA-N 0.000 abstract 1
UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 abstract 1
229930010555 Inosine Natural products 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000000977 initiatory effect Effects 0.000 abstract 1
229960003786 inosine Drugs 0.000 abstract 1
230000036470 plasma concentration Effects 0.000 abstract 1
208000011580 syndromic disease Diseases 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IT8848444A 1988-09-28 1988-10-12 Composizione farmaceutica comprendente inosina,acido p-acetammidobenzoico e zidovudina per il trattamento dell'aids e sindromi correlate IT1235032B (it)

Priority Applications (8)

Application Number	Priority Date	Filing Date	Title
IT8848444A IT1235032B (it)	1988-10-12	1988-10-12	Composizione farmaceutica comprendente inosina,acido p-acetammidobenzoico e zidovudina per il trattamento dell'aids e sindromi correlate
EP89830422A EP0362162B1 (en)	1988-09-28	1989-09-27	Pharmaceutical composition comprising zidovudine and inosiplex or components thereof for the treatment of aids and aids-related syndromes
ES198989830422T ES2038847T3 (es)	1988-09-28	1989-09-27	Proceso para la preparacion de una composicion farmacutica conteniendo zidovudine e inosiplex para el tratamiento del sida y sindromes afines.
DE8989830422T DE68900926D1 (de)	1988-09-28	1989-09-27	Pharmazeutische zubereitung, die zidovudin und inosiplex oder bestandteile davon enthaelt, fuer die behandlung von aids-verwandten syndromen.
JP1251704A JPH02142733A (ja)	1988-09-28	1989-09-27	ジドブジン含有エイズ治療剤
AT89830422T ATE72981T1 (de)	1988-09-28	1989-09-27	Pharmazeutische zubereitung, die zidovudin und inosiplex oder bestandteile davon enthaelt, fuer die behandlung von aids-verwandten syndromen.
US07/595,758 US5108993A (en)	1988-09-28	1990-10-09	Pharmaceutical composition comprising zidovudine and inosiplex or components thereof for the treatment of aids-related syndromes
GR920400777T GR3004419T3 (it)	1988-09-28	1992-04-20

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT8848444A IT1235032B (it)	1988-10-12	1988-10-12	Composizione farmaceutica comprendente inosina,acido p-acetammidobenzoico e zidovudina per il trattamento dell'aids e sindromi correlate

Publications (2)

Publication Number	Publication Date
IT8848444A0 IT8848444A0 (it)	1988-10-12
IT1235032B true IT1235032B (it)	1992-06-17

Family

ID=11266580

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT8848444A IT1235032B (it)	1988-09-28	1988-10-12	Composizione farmaceutica comprendente inosina,acido p-acetammidobenzoico e zidovudina per il trattamento dell'aids e sindromi correlate

Country Status (1)

Country	Link
IT (1)	IT1235032B (it)

1988
- 1988-10-12 IT IT8848444A patent/IT1235032B/it active

Also Published As

Publication number	Publication date
IT8848444A0 (it)	1988-10-12

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Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19950908