IT1238080B - Combinazione di un inibitore della hmg coa reduttasi e di un inibitoredella squalene sintetasi per fare abbassare il colesterolo nel siero - Google Patents

Combinazione di un inibitore della hmg coa reduttasi e di un inibitoredella squalene sintetasi per fare abbassare il colesterolo nel siero

Info

Publication number
IT1238080B
IT1238080B IT01922090A IT1922090A IT1238080B IT 1238080 B IT1238080 B IT 1238080B IT 01922090 A IT01922090 A IT 01922090A IT 1922090 A IT1922090 A IT 1922090A IT 1238080 B IT1238080 B IT 1238080B
Authority
IT
Italy
Prior art keywords
inhibitor
synthetase
combination
coa reductase
serum cholesterol
Prior art date
Application number
IT01922090A
Other languages
English (en)
Other versions
IT9019220A1 (it
IT9019220A0 (it
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT9019220A0 publication Critical patent/IT9019220A0/it
Publication of IT9019220A1 publication Critical patent/IT9019220A1/it
Application granted granted Critical
Publication of IT1238080B publication Critical patent/IT1238080B/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT01922090A 1989-02-01 1990-02-01 Combinazione di un inibitore della hmg coa reduttasi e di un inibitoredella squalene sintetasi per fare abbassare il colesterolo nel siero IT1238080B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30534389A 1989-02-01 1989-02-01

Publications (3)

Publication Number Publication Date
IT9019220A0 IT9019220A0 (it) 1990-02-01
IT9019220A1 IT9019220A1 (it) 1991-08-01
IT1238080B true IT1238080B (it) 1993-07-05

Family

ID=23180410

Family Applications (1)

Application Number Title Priority Date Filing Date
IT01922090A IT1238080B (it) 1989-02-01 1990-02-01 Combinazione di un inibitore della hmg coa reduttasi e di un inibitoredella squalene sintetasi per fare abbassare il colesterolo nel siero

Country Status (6)

Country Link
JP (1) JPH02235821A (it)
CA (1) CA2007643A1 (it)
DE (1) DE4002836C2 (it)
FR (1) FR2642311B1 (it)
GB (1) GB2227662B (it)
IT (1) IT1238080B (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05239075A (ja) * 1991-08-27 1993-09-17 Eisai Co Ltd 含リンイソプレノイド誘導体
HUT72307A (en) 1993-03-08 1996-04-29 Eisai Co Ltd Phosphonic acid derivatives
AU4988100A (en) * 1999-05-07 2000-11-21 Brigham And Women's Hospital Use of hmgcoa reductase inhibitors in the prevention of diseases whose pathogenesis is dependent on neovascularization
DE10038043B4 (de) * 2000-08-02 2006-09-07 Walter, Michael, Dr. Phamakologisch wirksame Substanz zur Behandlung kardiovaskulärer Erkrankungen
AUPR549901A0 (en) 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
BR0211673A (pt) 2001-07-27 2004-07-13 Vital Health Sciences Pty Ltd Terapia dermal utilizando derivados de fosfato de agentes de transferência de elétrons
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
AU2003901812A0 (en) * 2003-04-15 2003-05-01 Vital Health Sciences Pty Ltd Phosphates of secondary alcohols
JP4847437B2 (ja) 2004-03-03 2011-12-28 バイタル ヘルス サイエンシズ プロプライアタリー リミティド アルカロイド製剤
AR054368A1 (es) * 2005-06-01 2007-06-20 Takeda Pharmaceutical Metodo para tratar hiperlipidemia
US9168216B2 (en) 2005-06-17 2015-10-27 Vital Health Sciences Pty. Ltd. Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
EP2531047B1 (en) 2010-02-05 2024-11-13 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
ES2829386T3 (es) 2010-03-30 2021-05-31 Phosphagenics Ltd Parche de administración transdérmica
WO2012122586A1 (en) 2011-03-15 2012-09-20 Phosphagenics Limited New composition
MX383940B (es) 2015-12-09 2025-03-14 Phosphagenics Ltd Formulación farmacéutica que contiene tocol fosfato.
IL267006B2 (en) 2016-12-21 2024-11-01 Phosphagenics Ltd Process for phosphorylation of a complex alcohol with p4o10 at high temperatures, and products thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2009918A6 (es) * 1987-05-22 1989-10-16 Squibb & Sons Inc Procedimiento para preparar inhibidores de hmg-coa-reductasa que contienen fosforo.
US4871721A (en) * 1988-01-11 1989-10-03 E. R. Squibb & Sons, Inc. Phosphorus-containing squalene synthetase inhibitors
CA2003478A1 (en) * 1988-12-12 1990-06-12 Leonard G. Dennick Combination of an hmg coa reductase inhibitor and other type of serum cholesterol reducing agent and method for lowering serum cholesterol using such combination

Also Published As

Publication number Publication date
GB2227662B (en) 1993-03-17
DE4002836A1 (de) 1990-08-02
IT9019220A1 (it) 1991-08-01
FR2642311B1 (fr) 1991-10-25
IT9019220A0 (it) 1990-02-01
GB2227662A (en) 1990-08-08
DE4002836C2 (de) 1998-08-27
GB9002016D0 (en) 1990-03-28
FR2642311A1 (fr) 1990-08-03
CA2007643A1 (en) 1990-08-01
JPH02235821A (ja) 1990-09-18

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970227