IT1244500B - Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana - Google Patents

Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana

Info

Publication number
IT1244500B
IT1244500B ITRM910188A ITRM910188A IT1244500B IT 1244500 B IT1244500 B IT 1244500B IT RM910188 A ITRM910188 A IT RM910188A IT RM910188 A ITRM910188 A IT RM910188A IT 1244500 B IT1244500 B IT 1244500B
Authority
IT
Italy
Prior art keywords
trometamine
calcitonin
pharmaceutical compositions
administrable
compositions based
Prior art date
Application number
ITRM910188A
Other languages
English (en)
Inventor
Evaristo Bertone
Original Assignee
Pulitzer Italiana
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pulitzer Italiana filed Critical Pulitzer Italiana
Priority to ITRM910188A priority Critical patent/IT1244500B/it
Publication of ITRM910188A0 publication Critical patent/ITRM910188A0/it
Priority to AT91120965T priority patent/ATE126064T1/de
Priority to EP91120965A priority patent/EP0504483B1/en
Priority to DE69112028T priority patent/DE69112028T2/de
Priority to ES91120965T priority patent/ES2077146T3/es
Publication of ITRM910188A1 publication Critical patent/ITRM910188A1/it
Application granted granted Critical
Publication of IT1244500B publication Critical patent/IT1244500B/it
Priority to GR950402860T priority patent/GR3017760T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Oggetto dell'invenzione sono composizioni farmaceutiche atte ad essere somministrate per via rettale, comprendenti: a) una calcitonina liofilizzata su opportuno supporto; b) un tampone acquoso appropriato, costituito da sali di trometamina con acidi organici, dotato di proprietà surfattanti e attivanti l'assorbimento del principio attivo; c) un conservante antibatterico; d) possono essere impiegati anche additivi vari appartenenti alla classe di tensio-attivi, disperdenti, stabilizzanti, carriera ecc.; e) una massa per supposte lipofila o idrofila.
ITRM910188A 1991-03-21 1991-03-21 Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana IT1244500B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ITRM910188A IT1244500B (it) 1991-03-21 1991-03-21 Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana
AT91120965T ATE126064T1 (de) 1991-03-21 1991-12-06 Arzneizusammensetzungen zur rektalen verabreichung enthaltend gefriergetrocknetes calcitonin.
EP91120965A EP0504483B1 (en) 1991-03-21 1991-12-06 Rectal compositions containing lyophilized calcitonin
DE69112028T DE69112028T2 (de) 1991-03-21 1991-12-06 Arzneizusammensetzungen zur rektalen Verabreichung enthaltend gefriergetrocknetes Calcitonin.
ES91120965T ES2077146T3 (es) 1991-03-21 1991-12-06 Composiciones farmaceuticas rectales que contienen calcitonina liofilizada.
GR950402860T GR3017760T3 (en) 1991-03-21 1995-10-18 Rectal compositions containing lyophilized calcitonin.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM910188A IT1244500B (it) 1991-03-21 1991-03-21 Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana

Publications (3)

Publication Number Publication Date
ITRM910188A0 ITRM910188A0 (it) 1991-03-21
ITRM910188A1 ITRM910188A1 (it) 1992-09-21
IT1244500B true IT1244500B (it) 1994-07-15

Family

ID=11399989

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM910188A IT1244500B (it) 1991-03-21 1991-03-21 Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana

Country Status (6)

Country Link
EP (1) EP0504483B1 (it)
AT (1) ATE126064T1 (it)
DE (1) DE69112028T2 (it)
ES (1) ES2077146T3 (it)
GR (1) GR3017760T3 (it)
IT (1) IT1244500B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0776527A (ja) * 1993-06-28 1995-03-20 Hayashibara Biochem Lab Inc 半固形製剤とその製造方法
EP0726075A1 (en) * 1995-02-08 1996-08-14 Therapicon Srl Pharmaceutical non-inorganic saline solutions for endonasal administration
IT1298780B1 (it) * 1998-03-24 2000-02-02 Therapicon Srl Preparazioni parenterali a base di calcitonina
JP6378475B2 (ja) * 2012-12-05 2018-08-22 ミヨシ油脂株式会社 親水性室温イオン液体とその用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2092002B (en) * 1981-01-14 1985-09-11 Toyo Jozo Kk Suppositories injectable solutions
US4774091A (en) * 1983-10-14 1988-09-27 Sumitomo Pharmaceuticals Company, Ltd. Long-term sustained-release preparation
JP2514249B2 (ja) * 1989-05-23 1996-07-10 帝人株式会社 安定化されたカルシトニン類医薬組成物

Also Published As

Publication number Publication date
ATE126064T1 (de) 1995-08-15
EP0504483B1 (en) 1995-08-09
DE69112028T2 (de) 1996-04-18
DE69112028D1 (de) 1995-09-14
EP0504483A1 (en) 1992-09-23
ITRM910188A0 (it) 1991-03-21
ITRM910188A1 (it) 1992-09-21
ES2077146T3 (es) 1995-11-16
GR3017760T3 (en) 1996-01-31

Similar Documents

Publication Publication Date Title
AR092919A2 (es) Composicion farmaceutica liquida
ES2071484T3 (es) Derivados de 2,4-diaminoquinazolinas para aumentar la actividad antitumoral.
EP0253887A1 (en) Low dosage of interferon to enhance vaccine efficiency.
ES2058892T3 (es) Uso de omeprazol como agente antimicrobiano.
PT88404A (pt) Dosage form comprising fast agent delivery followed by slow agent delivery
CL2008003938A1 (es) Uso de escitalopram o de una sal farmaceuticamente aceptable del mismo para preparar un medicamento util en el tratamiento del desorden de estres postraumatico (divisional sol. 1799-00).
ES2090714T3 (es) Matriz de vidrio de carbohidrato para la liberacion prolongada de un agente terapeutico.
ZA895936B (en) Pharmaceutical compositions comprising selected lactobacillus strains
ES2129423T3 (es) Vacunas.
UA26303A1 (uk) Фармацевтичhа композиція, яка має імуhосупресорhу та аhтимікробhу активhість
ES2197792A1 (es) Formulaciones farmaceuticas y metodos que contienen morfina intranasal.
ATE94396T1 (de) N-acetylneuraminsaeure enthaltende expektorantien.
FR2680172B1 (fr) Nouvelles piperazinylalcoyl-3 dihydro-2,3 4h-benzoxazine-1,3 ones-4 substituees, leur preparation et leur application en therapeutique.
IT1244500B (it) Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana
DE3873603D1 (de) Zusammensetzung gegen coccidiosis.
ATE254851T1 (de) Iod-herstellungszusammensetzung
ES2160834T3 (es) Derivado de fenil pirimidina opticamente activo como agente analgesico.
GT198400146A (es) Nuevos derivados de cefalosporina.
AR015956A1 (es) Composiciones de citoquinas oromucosales y usos de las mismas
SE8501532D0 (sv) Nya lekemedelskombinationer med synergistisk verkan och forfarande for deras framstellning
SE0001916D0 (sv) Novel formulation
ES2074332T3 (es) Derivados de polihidroxiciclopentano, su preparacion y su uso terapeutico.
ES2191908T3 (es) 4-aminopirrol(3,2-d)pirimidinas como antagonistas del receptor del neuropeptido.
ATE83379T1 (de) Coccidiozide mittel.
ES2092559T3 (es) Formulacion farmaceutica que contiene penciclovir.

Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960519