IT1244500B - Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana - Google Patents

Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana

Info

Publication number
IT1244500B
IT1244500B ITRM910188A ITRM910188A IT1244500B IT 1244500 B IT1244500 B IT 1244500B IT RM910188 A ITRM910188 A IT RM910188A IT RM910188 A ITRM910188 A IT RM910188A IT 1244500 B IT1244500 B IT 1244500B
Authority
IT
Italy
Prior art keywords
trometamine
calcitonin
pharmaceutical compositions
administrable
compositions based
Prior art date
Application number
ITRM910188A
Other languages
English (en)
Inventor
Evaristo Bertone
Original Assignee
Pulitzer Italiana
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pulitzer Italiana filed Critical Pulitzer Italiana
Priority to ITRM910188A priority Critical patent/IT1244500B/it
Publication of ITRM910188A0 publication Critical patent/ITRM910188A0/it
Priority to EP91120965A priority patent/EP0504483B1/en
Priority to ES91120965T priority patent/ES2077146T3/es
Priority to DE69112028T priority patent/DE69112028T2/de
Priority to AT91120965T priority patent/ATE126064T1/de
Publication of ITRM910188A1 publication Critical patent/ITRM910188A1/it
Application granted granted Critical
Publication of IT1244500B publication Critical patent/IT1244500B/it
Priority to GR950402860T priority patent/GR3017760T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Oggetto dell'invenzione sono composizioni farmaceutiche atte ad essere somministrate per via rettale, comprendenti: a) una calcitonina liofilizzata su opportuno supporto; b) un tampone acquoso appropriato, costituito da sali di trometamina con acidi organici, dotato di proprietà surfattanti e attivanti l'assorbimento del principio attivo; c) un conservante antibatterico; d) possono essere impiegati anche additivi vari appartenenti alla classe di tensio-attivi, disperdenti, stabilizzanti, carriera ecc.; e) una massa per supposte lipofila o idrofila.
ITRM910188A 1991-03-21 1991-03-21 Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana IT1244500B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ITRM910188A IT1244500B (it) 1991-03-21 1991-03-21 Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana
EP91120965A EP0504483B1 (en) 1991-03-21 1991-12-06 Rectal compositions containing lyophilized calcitonin
ES91120965T ES2077146T3 (es) 1991-03-21 1991-12-06 Composiciones farmaceuticas rectales que contienen calcitonina liofilizada.
DE69112028T DE69112028T2 (de) 1991-03-21 1991-12-06 Arzneizusammensetzungen zur rektalen Verabreichung enthaltend gefriergetrocknetes Calcitonin.
AT91120965T ATE126064T1 (de) 1991-03-21 1991-12-06 Arzneizusammensetzungen zur rektalen verabreichung enthaltend gefriergetrocknetes calcitonin.
GR950402860T GR3017760T3 (en) 1991-03-21 1995-10-18 Rectal compositions containing lyophilized calcitonin.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM910188A IT1244500B (it) 1991-03-21 1991-03-21 Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana

Publications (3)

Publication Number Publication Date
ITRM910188A0 ITRM910188A0 (it) 1991-03-21
ITRM910188A1 ITRM910188A1 (it) 1992-09-21
IT1244500B true IT1244500B (it) 1994-07-15

Family

ID=11399989

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM910188A IT1244500B (it) 1991-03-21 1991-03-21 Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana

Country Status (6)

Country Link
EP (1) EP0504483B1 (it)
AT (1) ATE126064T1 (it)
DE (1) DE69112028T2 (it)
ES (1) ES2077146T3 (it)
GR (1) GR3017760T3 (it)
IT (1) IT1244500B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0776527A (ja) * 1993-06-28 1995-03-20 Hayashibara Biochem Lab Inc 半固形製剤とその製造方法
DE726075T1 (de) * 1995-02-08 1996-12-12 Therapicon Srl Nicht-inorganische pharmazeutische salzige Lösungen zur endonasale Verabreichung
IT1298780B1 (it) * 1998-03-24 2000-02-02 Therapicon Srl Preparazioni parenterali a base di calcitonina
JP6378475B2 (ja) * 2012-12-05 2018-08-22 ミヨシ油脂株式会社 親水性室温イオン液体とその用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE460638B (sv) * 1981-01-14 1989-11-06 Toyo Jozo Kk Suppositoriepreparat med foerbaettrad absorptionsegenskap
US4774091A (en) * 1983-10-14 1988-09-27 Sumitomo Pharmaceuticals Company, Ltd. Long-term sustained-release preparation
JP2514249B2 (ja) * 1989-05-23 1996-07-10 帝人株式会社 安定化されたカルシトニン類医薬組成物

Also Published As

Publication number Publication date
EP0504483B1 (en) 1995-08-09
ES2077146T3 (es) 1995-11-16
EP0504483A1 (en) 1992-09-23
GR3017760T3 (en) 1996-01-31
ITRM910188A0 (it) 1991-03-21
DE69112028D1 (de) 1995-09-14
DE69112028T2 (de) 1996-04-18
ATE126064T1 (de) 1995-08-15
ITRM910188A1 (it) 1992-09-21

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960519