IT1245889B - Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari. - Google Patents
Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari.Info
- Publication number
- IT1245889B IT1245889B ITBO910112A ITBO910112A IT1245889B IT 1245889 B IT1245889 B IT 1245889B IT BO910112 A ITBO910112 A IT BO910112A IT BO910112 A ITBO910112 A IT BO910112A IT 1245889 B IT1245889 B IT 1245889B
- Authority
- IT
- Italy
- Prior art keywords
- gastro
- resistant
- pharmaceutical formulations
- tablets
- oral use
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Formulazioni farmaceutiche per uso orale ricoperte da una pellicola gastroresistente enterosolubile, preferibilmente scelte tra granulati gastroresistenti, compresse gastroresistenti, capsule gastroresistenti di gelatina dura contenenti polveri o granulati o due o più compresse o sospensioni oleose, capsule gastroresistenti di gelatina molle contenenti sospensioni oleose e capsule di gelatina dura contenenti granulati gastroresistenti o due o più compresse gastroresistenti, contenenti quantità terapeuticamente efficaci di sali degli acidi biliari con metalli alcalini o con basi organiche, processo per la loro preparazione e loro uso terapeutico nel trattamento delle calcolosi biliari, delle dispepsie biliari, della cirrosi biliare e delle epatopatie croniche e colestatiche.
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITBO910112A IT1245889B (it) | 1991-04-12 | 1991-04-12 | Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari. |
| US07/861,461 US5302398A (en) | 1991-04-12 | 1992-04-01 | Gastroresistant pharmaceutical formulations for oral administration containing salts of bile acids |
| DK92105714.7T DK0510404T3 (da) | 1991-04-12 | 1992-04-02 | Gastroresistente farmaceutiske formuleringer til oral administration indeholdende galdesyresalte |
| DE69212882T DE69212882T2 (de) | 1991-04-12 | 1992-04-02 | Gallensäuresalze enthaltende magenstabile pharmazeutische Zusammensetzung zur oralen Verabreichung |
| TW081102516A TW202389B (it) | 1991-04-12 | 1992-04-02 | |
| ES92105714T ES2090394T3 (es) | 1991-04-12 | 1992-04-02 | Formulados farmaceuticos gastroresistentes para administracion oral conteniendo sales de acidos biliares. |
| EP92105714A EP0510404B1 (en) | 1991-04-12 | 1992-04-02 | Gastroresistant pharmaceutical formulations for oral administration containing salts of bile acids |
| JP4091129A JP2509044B2 (ja) | 1991-04-12 | 1992-04-10 | 胆汁酸塩を含有する胃液耐性のある経口投与用製剤 |
| CA002065809A CA2065809C (en) | 1991-04-12 | 1992-04-10 | Gastroresistant pharmaceutical formulations for oral administration containing salts of bile acids |
| KR1019920006051A KR970005175B1 (ko) | 1991-04-12 | 1992-04-11 | 담즙산의 염을 함유하는 경구용 위내성 의약 포뮬레이션 |
| GR960402160T GR3020843T3 (en) | 1991-04-12 | 1996-08-22 | Gastroresistant pharmaceutical formulations for oral administration containing salts of bile acids |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITBO910112A IT1245889B (it) | 1991-04-12 | 1991-04-12 | Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITBO910112A0 ITBO910112A0 (it) | 1991-04-12 |
| ITBO910112A1 ITBO910112A1 (it) | 1992-10-12 |
| IT1245889B true IT1245889B (it) | 1994-10-25 |
Family
ID=11337388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITBO910112A IT1245889B (it) | 1991-04-12 | 1991-04-12 | Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5302398A (it) |
| EP (1) | EP0510404B1 (it) |
| JP (1) | JP2509044B2 (it) |
| KR (1) | KR970005175B1 (it) |
| CA (1) | CA2065809C (it) |
| DE (1) | DE69212882T2 (it) |
| DK (1) | DK0510404T3 (it) |
| ES (1) | ES2090394T3 (it) |
| GR (1) | GR3020843T3 (it) |
| IT (1) | IT1245889B (it) |
| TW (1) | TW202389B (it) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE171874T1 (de) * | 1993-08-30 | 1998-10-15 | Medichemie Ag | Ursodeoxycholsäure enthaltendes arzneimittel in flüssiger darreichungsform |
| KR100578669B1 (ko) * | 1997-05-29 | 2006-12-07 | 동아제약주식회사 | 우르소데옥시콜린산을함유하는투명연질캅셀 |
| DE29717252U1 (de) * | 1997-09-26 | 1998-02-19 | Dr. Falk Pharma GmbH, 79108 Freiburg | Arzneimittelkit aus einem Budesonid-haltigen und einem Ursodesoxycholsäure-haltigen Arzneimittel zur Behandlung von cholestatischen Lebererkrankungen |
| US7303768B2 (en) | 1998-07-24 | 2007-12-04 | Seo Hong Yoo | Preparation of aqueous clear solution dosage forms with bile acids |
| US20050158408A1 (en) * | 1998-07-24 | 2005-07-21 | Yoo Seo H. | Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof |
| CA2338457C (en) | 1998-07-24 | 2009-11-17 | Seo Hong Yoo | Preparation of aqueous clear solution dosage forms with bile acids |
| US7772220B2 (en) * | 2004-10-15 | 2010-08-10 | Seo Hong Yoo | Methods and compositions for reducing toxicity of a pharmaceutical compound |
| DE19906290A1 (de) * | 1999-02-15 | 2000-08-17 | Falk Pharma Gmbh | Arzneimittel zur Behandlung bzw. Prävention von Darmkrebs |
| FR2796271B1 (fr) | 1999-07-15 | 2002-01-11 | Oreal | Composition sans cire structuree sous forme rigide par un polymere |
| FR2796272B1 (fr) | 1999-07-15 | 2003-09-19 | Oreal | Composition sans cire structuree sous forme rigide par un polymere |
| DE60019541T2 (de) * | 1999-12-28 | 2006-03-09 | L'oreal | Strukturierte langhaltige Zubereitung enthaltend ein Polymer und pastöse Fettstoffe |
| FR2804018B1 (fr) | 2000-01-24 | 2008-07-11 | Oreal | Composition sans transfert structuree sous forme rigide par un polymere |
| CN100558407C (zh) * | 2000-02-04 | 2009-11-11 | 柳署弘 | 制备含有胆汁酸的澄清水溶液剂型 |
| JP2002034198A (ja) * | 2000-07-18 | 2002-01-31 | Minebea Co Ltd | スピンドルモータ |
| US8080257B2 (en) * | 2000-12-12 | 2011-12-20 | L'oreal S.A. | Cosmetic compositions containing at least one hetero polymer and at least one film-forming silicone resin and methods of using |
| US6835399B2 (en) * | 2000-12-12 | 2004-12-28 | L'ORéAL S.A. | Cosmetic composition comprising a polymer blend |
| US20020168335A1 (en) * | 2000-12-12 | 2002-11-14 | Nathalie Collin | Cosmetic composition comprising a wax and a polymer |
| FR2817739B1 (fr) * | 2000-12-12 | 2005-01-07 | Oreal | Composition cosmetique coloree transparente ou translucide |
| EP1343458B1 (fr) * | 2000-12-12 | 2008-02-13 | L'oreal | Composition cosmetique comprenant un melange de polymeres |
| WO2002047623A1 (en) | 2000-12-12 | 2002-06-20 | L'oreal Sa | Composition comprising at least one heteropolymer and at least one inert filler and methods for use |
| US6881400B2 (en) * | 2000-12-12 | 2005-04-19 | L'oreal S.A. | Use of at least one polyamide polymer in a mascara composition for increasing the adhesion of and/or expressly loading make-up deposited on eyelashes |
| US20020107314A1 (en) * | 2000-12-12 | 2002-08-08 | Carlos Pinzon | Compositions containing heteropolymers and oil-soluble esters and methods of using same |
| WO2002047626A1 (en) * | 2000-12-12 | 2002-06-20 | L'oreal Sa | Cosmetic composition comprising heteropolymers and a solid substance and method of using same |
| FR2817740B1 (fr) * | 2000-12-12 | 2006-08-04 | Oreal | Procede de fabrication d'une composition cosmetique coloree de maquillage a transmittance controlee |
| US7276547B2 (en) * | 2000-12-12 | 2007-10-02 | L'oreal S.A. | Compositions comprising heteropolymers and at least one oil-soluble polymers chosen from alkyl celluloses and alkylated guar gums |
| WO2002047624A1 (en) * | 2000-12-12 | 2002-06-20 | L'oreal Sa | Cosmetic compositions containing at least one heteropolymer and at least one gelling agent and methods of using the same |
| WO2002047628A1 (en) * | 2000-12-13 | 2002-06-20 | L'oréal | Composition structured with a polymer containing a heteroatom and an organogelator |
| FR2819400B1 (fr) * | 2001-01-15 | 2004-12-03 | Oreal | Composition cosmetique de maquillage ou de soin des matieres keratiniques comprenant un melange de polymeres |
| US7025953B2 (en) * | 2001-01-17 | 2006-04-11 | L'oreal S.A. | Nail polish composition comprising a polymer |
| FR2819399B1 (fr) * | 2001-01-17 | 2003-02-21 | Oreal | Composition cosmetique contenant un polymere et une huile fluoree |
| JP5502254B2 (ja) * | 2001-01-31 | 2014-05-28 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | 少なくとも2種類の異なる被覆ペレット形から成る多粒子剤形 |
| US6716420B2 (en) * | 2001-10-05 | 2004-04-06 | L′Oreal | Methods of use and of making a mascara comprising at least one coloring agent and at least one heteropolymer |
| FR2832060B1 (fr) * | 2001-11-09 | 2004-07-09 | Oreal | Composition contenant un ester n-acyle d'acide amine et un filtre uv structuree par un polyamide |
| US6927071B2 (en) * | 2001-12-07 | 2005-08-09 | Beckman Coulter, Inc. | Method for reducing non-specific aggregation of latex microparticles in the presence of serum or plasma |
| US20080057011A1 (en) * | 2001-12-12 | 2008-03-06 | L'oreal S.A., | Composition structured with a polymer containing a heteroatom and an Organogelator |
| US20050008598A1 (en) | 2003-07-11 | 2005-01-13 | Shaoxiang Lu | Cosmetic compositions comprising a structuring agent, silicone powder and swelling agent |
| US20040247549A1 (en) * | 2002-06-12 | 2004-12-09 | L'oreal S.A. | Cosmetic emulsions containing at least one hetero polymer and at least one sunscreen and methods of using the same |
| US7008629B2 (en) * | 2002-07-22 | 2006-03-07 | L'ORéAL S.A. | Compositions comprising at least one heteropolymer and fibers, and methods of using the same |
| US20040166133A1 (en) * | 2003-01-21 | 2004-08-26 | L'oreal | Method of making a mascara composition comprising polyamide polymer and at least one solid substance having a melting point of 45oC or greater |
| US20040241252A1 (en) * | 2003-05-29 | 2004-12-02 | Abney Christopher Charles | Pharmaceutical compositions for oral administration comprising lithium carbonate, processes of making the same, and methods of administering the same |
| US20040261311A1 (en) * | 2003-06-13 | 2004-12-30 | Mike Mattlage | Fishing hook |
| US7145125B2 (en) * | 2003-06-23 | 2006-12-05 | Advanced Optical Technologies, Llc | Integrating chamber cone light using LED sources |
| ES2339790T3 (es) * | 2004-08-30 | 2010-05-25 | Seo Hong Yoo | Efecto neuroprotector de udca solubilizado en modelo isquemico focal. |
| DE602005027727D1 (de) * | 2004-10-15 | 2011-06-09 | Seo Hong Yoo | Zusammensetzungen zur verringerung der toxizität von cisplatin, carboplatin und oxaliplatin |
| EP1814558B1 (en) * | 2004-11-01 | 2010-12-15 | Seo Hong Yoo | Methods and compositions for reducing neurodegeneration in amyotrophic lateral sclerosis |
| US8865197B2 (en) * | 2005-09-06 | 2014-10-21 | Israel Oceanographic And Limnological Research Ltd. | Food formulation for aquatic animals with integrated targeted delivery of bioactive agents |
| JP5856372B2 (ja) * | 2008-02-20 | 2016-02-09 | グノーシス・エツセ・ピー・アー | 葉酸塩、これらの組成物および使用 |
| WO2010080730A2 (en) * | 2009-01-09 | 2010-07-15 | Mayo Foundation For Medical Education And Research | Methods and materials for delivering bile acids |
| KR20250008786A (ko) | 2014-07-29 | 2025-01-15 | 센젠 하이타이드 바이오파마슈티컬 리미티드 | 베르베린 염, 우르소데옥시콜산 염 및 병용물, 이들의 제조 및 응용 방법 |
| US20210046011A1 (en) | 2019-08-12 | 2021-02-18 | Massachusetts Institute Of Technology | Articles and methods for administration of therapeutic agents |
| CN110898036A (zh) * | 2019-12-18 | 2020-03-24 | 乐普制药科技有限公司 | 一种熊去氧胆酸缓释肠溶胶囊及其制备方法 |
| AU2022261742A1 (en) * | 2021-04-19 | 2023-11-02 | Neurotrauma Sciences Llc | Salts and crystalline forms of (3e) 3-[o-[(phosphonooxy)methyl]oxime]-pregn-4-ene-3, 20-dione and related uses |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3634584A (en) * | 1969-02-13 | 1972-01-11 | American Home Prod | Sustained action dosage form |
| FR2358144A1 (fr) * | 1976-07-13 | 1978-02-10 | Lipha | Nouvelle composition medicamenteuse pour le traitement de la lithiase biliaire |
| IT1101649B (it) * | 1978-12-15 | 1985-10-07 | Lehner Ag | Composizione farmaceutica ad azione prolungata contenente acidi biliari |
| FR2471186A1 (fr) * | 1979-12-10 | 1981-06-19 | Roussel Uclaf | Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation |
| IL68769A (en) * | 1983-05-23 | 1986-02-28 | Hadassah Med Org | Pharmaceutical compositions containing insulin for oral administration |
| US4775536A (en) * | 1986-02-24 | 1988-10-04 | Bristol-Myers Company | Enteric coated tablet and process for making |
| IT1212141B (it) * | 1987-06-03 | 1989-11-08 | So Ri Far S R L | Composizioni farmaceutiche per la prevenzione e terapia della calcolosi delle vie biliari e della dispepsia biliare. |
| US4891223A (en) * | 1987-09-03 | 1990-01-02 | Air Products And Chemicals, Inc. | Controlled release delivery coating formulation for bioactive substances |
| US5047258A (en) * | 1989-07-14 | 1991-09-10 | Sterling Drug Inc. | Aqueous spray-coating process |
-
1991
- 1991-04-12 IT ITBO910112A patent/IT1245889B/it active IP Right Grant
-
1992
- 1992-04-01 US US07/861,461 patent/US5302398A/en not_active Expired - Fee Related
- 1992-04-02 EP EP92105714A patent/EP0510404B1/en not_active Expired - Lifetime
- 1992-04-02 TW TW081102516A patent/TW202389B/zh active
- 1992-04-02 DE DE69212882T patent/DE69212882T2/de not_active Expired - Fee Related
- 1992-04-02 DK DK92105714.7T patent/DK0510404T3/da active
- 1992-04-02 ES ES92105714T patent/ES2090394T3/es not_active Expired - Lifetime
- 1992-04-10 JP JP4091129A patent/JP2509044B2/ja not_active Expired - Fee Related
- 1992-04-10 CA CA002065809A patent/CA2065809C/en not_active Expired - Fee Related
- 1992-04-11 KR KR1019920006051A patent/KR970005175B1/ko not_active Expired - Fee Related
-
1996
- 1996-08-22 GR GR960402160T patent/GR3020843T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2065809A1 (en) | 1992-10-13 |
| DE69212882D1 (de) | 1996-09-26 |
| EP0510404B1 (en) | 1996-08-21 |
| DE69212882T2 (de) | 1997-01-23 |
| DK0510404T3 (da) | 1996-09-09 |
| US5302398A (en) | 1994-04-12 |
| GR3020843T3 (en) | 1996-11-30 |
| EP0510404A1 (en) | 1992-10-28 |
| CA2065809C (en) | 1999-01-12 |
| ITBO910112A1 (it) | 1992-10-12 |
| KR920019358A (ko) | 1992-11-19 |
| ITBO910112A0 (it) | 1991-04-12 |
| ES2090394T3 (es) | 1996-10-16 |
| JPH0597678A (ja) | 1993-04-20 |
| KR970005175B1 (ko) | 1997-04-14 |
| JP2509044B2 (ja) | 1996-06-19 |
| TW202389B (it) | 1993-03-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960307 |