IT1245889B - Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari. - Google Patents

Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari.

Info

Publication number
IT1245889B
IT1245889B ITBO910112A ITBO910112A IT1245889B IT 1245889 B IT1245889 B IT 1245889B IT BO910112 A ITBO910112 A IT BO910112A IT BO910112 A ITBO910112 A IT BO910112A IT 1245889 B IT1245889 B IT 1245889B
Authority
IT
Italy
Prior art keywords
gastro
resistant
pharmaceutical formulations
tablets
oral use
Prior art date
Application number
ITBO910112A
Other languages
English (en)
Inventor
Egidio Marchi
Gianfranco Tamagnone
Leone Gabriele Rotini
Original Assignee
Alfa Wassermann Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Wassermann Spa filed Critical Alfa Wassermann Spa
Publication of ITBO910112A0 publication Critical patent/ITBO910112A0/it
Priority to ITBO910112A priority Critical patent/IT1245889B/it
Priority to US07/861,461 priority patent/US5302398A/en
Priority to EP92105714A priority patent/EP0510404B1/en
Priority to ES92105714T priority patent/ES2090394T3/es
Priority to TW081102516A priority patent/TW202389B/zh
Priority to DE69212882T priority patent/DE69212882T2/de
Priority to DK92105714.7T priority patent/DK0510404T3/da
Priority to JP4091129A priority patent/JP2509044B2/ja
Priority to CA002065809A priority patent/CA2065809C/en
Priority to KR1019920006051A priority patent/KR970005175B1/ko
Publication of ITBO910112A1 publication Critical patent/ITBO910112A1/it
Application granted granted Critical
Publication of IT1245889B publication Critical patent/IT1245889B/it
Priority to GR960402160T priority patent/GR3020843T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Formulazioni farmaceutiche per uso orale ricoperte da una pellicola gastroresistente enterosolubile, preferibilmente scelte tra granulati gastroresistenti, compresse gastroresistenti, capsule gastroresistenti di gelatina dura contenenti polveri o granulati o due o più compresse o sospensioni oleose, capsule gastroresistenti di gelatina molle contenenti sospensioni oleose e capsule di gelatina dura contenenti granulati gastroresistenti o due o più compresse gastroresistenti, contenenti quantità terapeuticamente efficaci di sali degli acidi biliari con metalli alcalini o con basi organiche, processo per la loro preparazione e loro uso terapeutico nel trattamento delle calcolosi biliari, delle dispepsie biliari, della cirrosi biliare e delle epatopatie croniche e colestatiche.
ITBO910112A 1991-04-12 1991-04-12 Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari. IT1245889B (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
ITBO910112A IT1245889B (it) 1991-04-12 1991-04-12 Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari.
US07/861,461 US5302398A (en) 1991-04-12 1992-04-01 Gastroresistant pharmaceutical formulations for oral administration containing salts of bile acids
DK92105714.7T DK0510404T3 (da) 1991-04-12 1992-04-02 Gastroresistente farmaceutiske formuleringer til oral administration indeholdende galdesyresalte
ES92105714T ES2090394T3 (es) 1991-04-12 1992-04-02 Formulados farmaceuticos gastroresistentes para administracion oral conteniendo sales de acidos biliares.
TW081102516A TW202389B (it) 1991-04-12 1992-04-02
DE69212882T DE69212882T2 (de) 1991-04-12 1992-04-02 Gallensäuresalze enthaltende magenstabile pharmazeutische Zusammensetzung zur oralen Verabreichung
EP92105714A EP0510404B1 (en) 1991-04-12 1992-04-02 Gastroresistant pharmaceutical formulations for oral administration containing salts of bile acids
JP4091129A JP2509044B2 (ja) 1991-04-12 1992-04-10 胆汁酸塩を含有する胃液耐性のある経口投与用製剤
CA002065809A CA2065809C (en) 1991-04-12 1992-04-10 Gastroresistant pharmaceutical formulations for oral administration containing salts of bile acids
KR1019920006051A KR970005175B1 (ko) 1991-04-12 1992-04-11 담즙산의 염을 함유하는 경구용 위내성 의약 포뮬레이션
GR960402160T GR3020843T3 (en) 1991-04-12 1996-08-22 Gastroresistant pharmaceutical formulations for oral administration containing salts of bile acids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITBO910112A IT1245889B (it) 1991-04-12 1991-04-12 Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari.

Publications (3)

Publication Number Publication Date
ITBO910112A0 ITBO910112A0 (it) 1991-04-12
ITBO910112A1 ITBO910112A1 (it) 1992-10-12
IT1245889B true IT1245889B (it) 1994-10-25

Family

ID=11337388

Family Applications (1)

Application Number Title Priority Date Filing Date
ITBO910112A IT1245889B (it) 1991-04-12 1991-04-12 Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari.

Country Status (11)

Country Link
US (1) US5302398A (it)
EP (1) EP0510404B1 (it)
JP (1) JP2509044B2 (it)
KR (1) KR970005175B1 (it)
CA (1) CA2065809C (it)
DE (1) DE69212882T2 (it)
DK (1) DK0510404T3 (it)
ES (1) ES2090394T3 (it)
GR (1) GR3020843T3 (it)
IT (1) IT1245889B (it)
TW (1) TW202389B (it)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59407041D1 (de) * 1993-08-30 1998-11-12 Medichemie Ag Ursodeoxycholsäure enthaltendes Arzneimittel in flüssiger Darreichungsform
KR100578669B1 (ko) * 1997-05-29 2006-12-07 동아제약주식회사 우르소데옥시콜린산을함유하는투명연질캅셀
DE29717252U1 (de) * 1997-09-26 1998-02-19 Dr. Falk Pharma GmbH, 79108 Freiburg Arzneimittelkit aus einem Budesonid-haltigen und einem Ursodesoxycholsäure-haltigen Arzneimittel zur Behandlung von cholestatischen Lebererkrankungen
US20050158408A1 (en) * 1998-07-24 2005-07-21 Yoo Seo H. Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof
US7772220B2 (en) * 2004-10-15 2010-08-10 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
RU2224523C2 (ru) 1998-07-24 2004-02-27 Сео Хонг Ю Водный раствор, содержащий желчную кислоту, и способ его получения
US7303768B2 (en) * 1998-07-24 2007-12-04 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
DE19906290A1 (de) * 1999-02-15 2000-08-17 Falk Pharma Gmbh Arzneimittel zur Behandlung bzw. Prävention von Darmkrebs
FR2796271B1 (fr) 1999-07-15 2002-01-11 Oreal Composition sans cire structuree sous forme rigide par un polymere
FR2796272B1 (fr) 1999-07-15 2003-09-19 Oreal Composition sans cire structuree sous forme rigide par un polymere
ATE293425T1 (de) * 1999-12-28 2005-05-15 Oreal Strukturierte langhaltige zubereitung enthaltend ein polymer und pastöse fettstoffe
FR2804018B1 (fr) 2000-01-24 2008-07-11 Oreal Composition sans transfert structuree sous forme rigide par un polymere
EP1255566A2 (en) * 2000-02-04 2002-11-13 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
JP2002034198A (ja) * 2000-07-18 2002-01-31 Minebea Co Ltd スピンドルモータ
US6835399B2 (en) * 2000-12-12 2004-12-28 L'ORéAL S.A. Cosmetic composition comprising a polymer blend
US6881400B2 (en) * 2000-12-12 2005-04-19 L'oreal S.A. Use of at least one polyamide polymer in a mascara composition for increasing the adhesion of and/or expressly loading make-up deposited on eyelashes
DE60132805T2 (de) * 2000-12-12 2009-01-29 L'oreal Kosmetische zusammensetzung mit einem polymergemisch
US20020107314A1 (en) * 2000-12-12 2002-08-08 Carlos Pinzon Compositions containing heteropolymers and oil-soluble esters and methods of using same
WO2002047624A1 (en) * 2000-12-12 2002-06-20 L'oreal Sa Cosmetic compositions containing at least one heteropolymer and at least one gelling agent and methods of using the same
WO2002047623A1 (en) 2000-12-12 2002-06-20 L'oreal Sa Composition comprising at least one heteropolymer and at least one inert filler and methods for use
US7276547B2 (en) * 2000-12-12 2007-10-02 L'oreal S.A. Compositions comprising heteropolymers and at least one oil-soluble polymers chosen from alkyl celluloses and alkylated guar gums
US20020168335A1 (en) * 2000-12-12 2002-11-14 Nathalie Collin Cosmetic composition comprising a wax and a polymer
AU2001220877A1 (en) * 2000-12-12 2002-06-24 L'oreal S.A. Cosmetic composition comprising heteropolymers and a solid substance and method of using same
US8080257B2 (en) * 2000-12-12 2011-12-20 L'oreal S.A. Cosmetic compositions containing at least one hetero polymer and at least one film-forming silicone resin and methods of using
FR2817740B1 (fr) * 2000-12-12 2006-08-04 Oreal Procede de fabrication d'une composition cosmetique coloree de maquillage a transmittance controlee
FR2817739B1 (fr) * 2000-12-12 2005-01-07 Oreal Composition cosmetique coloree transparente ou translucide
WO2002047628A1 (en) * 2000-12-13 2002-06-20 L'oréal Composition structured with a polymer containing a heteroatom and an organogelator
FR2819400B1 (fr) * 2001-01-15 2004-12-03 Oreal Composition cosmetique de maquillage ou de soin des matieres keratiniques comprenant un melange de polymeres
FR2819399B1 (fr) * 2001-01-17 2003-02-21 Oreal Composition cosmetique contenant un polymere et une huile fluoree
US7025953B2 (en) * 2001-01-17 2006-04-11 L'oreal S.A. Nail polish composition comprising a polymer
US6897205B2 (en) * 2001-01-31 2005-05-24 Roehm Gmbh & Co. Kg Multi-particulate form of medicament, comprising at least two differently coated forms of pellet
US6716420B2 (en) 2001-10-05 2004-04-06 L′Oreal Methods of use and of making a mascara comprising at least one coloring agent and at least one heteropolymer
FR2832060B1 (fr) * 2001-11-09 2004-07-09 Oreal Composition contenant un ester n-acyle d'acide amine et un filtre uv structuree par un polyamide
US6927071B2 (en) * 2001-12-07 2005-08-09 Beckman Coulter, Inc. Method for reducing non-specific aggregation of latex microparticles in the presence of serum or plasma
US20080057011A1 (en) * 2001-12-12 2008-03-06 L'oreal S.A., Composition structured with a polymer containing a heteroatom and an Organogelator
US20040247549A1 (en) * 2002-06-12 2004-12-09 L'oreal S.A. Cosmetic emulsions containing at least one hetero polymer and at least one sunscreen and methods of using the same
US20050008598A1 (en) 2003-07-11 2005-01-13 Shaoxiang Lu Cosmetic compositions comprising a structuring agent, silicone powder and swelling agent
US7008629B2 (en) * 2002-07-22 2006-03-07 L'ORéAL S.A. Compositions comprising at least one heteropolymer and fibers, and methods of using the same
US20040166133A1 (en) * 2003-01-21 2004-08-26 L'oreal Method of making a mascara composition comprising polyamide polymer and at least one solid substance having a melting point of 45oC or greater
US20040241252A1 (en) * 2003-05-29 2004-12-02 Abney Christopher Charles Pharmaceutical compositions for oral administration comprising lithium carbonate, processes of making the same, and methods of administering the same
US20040261311A1 (en) * 2003-06-13 2004-12-30 Mike Mattlage Fishing hook
US7145125B2 (en) * 2003-06-23 2006-12-05 Advanced Optical Technologies, Llc Integrating chamber cone light using LED sources
DE602005019582D1 (de) * 2004-08-30 2010-04-08 Seo Hong Yoo Nervenschutzwirkung von aufgelöster udca bei einem fokalen ischämischen modell
KR20070084211A (ko) * 2004-10-15 2007-08-24 유서홍 약제학적 화합물의 독성을 감소시키기 위한 방법 및 조성물
JP2008518935A (ja) * 2004-11-01 2008-06-05 セオ ホン ユー 筋萎縮性側索硬化症の神経退行を減少させるための方法及び組成物
US8865197B2 (en) * 2005-09-06 2014-10-21 Israel Oceanographic And Limnological Research Ltd. Food formulation for aquatic animals with integrated targeted delivery of bioactive agents
EA017742B1 (ru) * 2008-02-20 2013-02-28 Ньосис С.П.А. Фолаты, композиции и применение указанных композиций
US20110268794A1 (en) * 2009-01-09 2011-11-03 Camilleri Michael L Methods and materials for delivering bile acids
IL282156B (en) * 2014-07-29 2022-07-01 Shenzhen Hightide Biopharmaceutical Ltd Berberine salts, ursodeoxycholic salts and combinations, methods of preparation and application thereof
JP2022544239A (ja) 2019-08-12 2022-10-17 マサチューセッツ インスティテュート オブ テクノロジー 治療薬の投与のための物品及び方法
CN110898036A (zh) * 2019-12-18 2020-03-24 乐普制药科技有限公司 一种熊去氧胆酸缓释肠溶胶囊及其制备方法
EP4326737A1 (en) * 2021-04-19 2024-02-28 Neurotrauma Sciences LLC Salts and crystalline forms of (3e) 3-[o-[(phosphonooxy)methyl]oxime]-pregn-4-ene-3, 20-dione and related uses

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3634584A (en) * 1969-02-13 1972-01-11 American Home Prod Sustained action dosage form
FR2358144A1 (fr) * 1976-07-13 1978-02-10 Lipha Nouvelle composition medicamenteuse pour le traitement de la lithiase biliaire
IT1101649B (it) * 1978-12-15 1985-10-07 Lehner Ag Composizione farmaceutica ad azione prolungata contenente acidi biliari
FR2471186A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation
IL68769A (en) * 1983-05-23 1986-02-28 Hadassah Med Org Pharmaceutical compositions containing insulin for oral administration
US4775536A (en) * 1986-02-24 1988-10-04 Bristol-Myers Company Enteric coated tablet and process for making
IT1212141B (it) * 1987-06-03 1989-11-08 So Ri Far S R L Composizioni farmaceutiche per la prevenzione e terapia della calcolosi delle vie biliari e della dispepsia biliare.
US4891223A (en) * 1987-09-03 1990-01-02 Air Products And Chemicals, Inc. Controlled release delivery coating formulation for bioactive substances
US5047258A (en) * 1989-07-14 1991-09-10 Sterling Drug Inc. Aqueous spray-coating process

Also Published As

Publication number Publication date
EP0510404B1 (en) 1996-08-21
DK0510404T3 (da) 1996-09-09
EP0510404A1 (en) 1992-10-28
CA2065809C (en) 1999-01-12
TW202389B (it) 1993-03-21
KR970005175B1 (ko) 1997-04-14
JP2509044B2 (ja) 1996-06-19
JPH0597678A (ja) 1993-04-20
DE69212882T2 (de) 1997-01-23
DE69212882D1 (de) 1996-09-26
CA2065809A1 (en) 1992-10-13
ITBO910112A1 (it) 1992-10-12
KR920019358A (ko) 1992-11-19
US5302398A (en) 1994-04-12
ES2090394T3 (es) 1996-10-16
GR3020843T3 (en) 1996-11-30
ITBO910112A0 (it) 1991-04-12

Similar Documents

Publication Publication Date Title
IT1245889B (it) Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari.
IT1245891B (it) Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali.
IT1245890B (it) Formulazioni farmaceutiche per uso orale gastroresistenti contenenti acidi biliari.
DK0794794T3 (da) Fremgangsmåde, sammensætninger og sæt til forögelse af oral biotilgængelighed for farmaceutiske midler
SE9704869D0 (sv) New pharmaceutical formulaton II
NO20032734D0 (no) Nye 1,2-difenylazetidinonderivater, fremgangsmåte for deres fremstilling, legemidler som inneholder nevnte forbindelser og anvendelse avdisse for behandling av sykdommer fra lipidstoffskiftet
EP4534527A2 (en) Methods for the treatment of cysteamine sensitive disorders
BR9610480A (pt) Inibição do fator alfa de necrose tumoral
RU95110938A (ru) Производные 1-(2-оксоацетил)пиперидин-2-карбоновых кислот, фармацевтическая композиция, способ лечения, способ получения
NO932979D0 (no) Orale doseringsformer med forsinket frigjoering for behandling av tarmforstyrrelser
DE69805001D1 (de) Osmotische darreichungsform mit zwei mantelschichten
DE69309540D1 (de) Orale Arzneimittel mit kolonspezifischer Freisetzung
IT1245761B (it) Formulazioni farmaceutiche contenenti glicosaminoglicani assorbibili per via orale.
UA41995C2 (uk) Лікарська форма азитроміцину з контрольованим вивільненням ( варіанти ), спосіб її введення, спосіб її виготовлення і спосіб лікування інфекційних захворювань ссавців з її використанням ( варіанти )
TR199701117T1 (xx) Proton-ifrazat�n� -�nleyici maddeler i�eren farmas�tik bile�im.
NO890194L (no) Galenisk middel.
ES2172239T3 (es) Sistema osmotico de liberacion de farmacos.
RU94045950A (ru) Фармацевтический препарат и способ его приготовления
NO20011211D0 (no) Multippel enhet for kontrollert mateffektuavhengig frigivelse av farmasøytiske preparater og fremgangsmÕter for fremstilling av samme
AR011231A1 (es) Uso de un mejorador de sensibilidad a la insulina y composicion farmaceutica que comprende dicho mejorador
BR0314797A (pt) Derivados da pirimidineamida e o uso dos mesmos
TR199900336T2 (xx) EAA antagonistleri olarak tetrahidrokinolin t�revleri.
ATE484295T1 (de) Zubereitungen zur erhöhung der bioverfügbarkeit von oral verabreichten pharmazeutischen verbindungen
AR002191A1 (es) Composicion farmaceutica oral de compuestos de piperidinoalcanol en forma de solucion, procedimiento para su preparacion
AU2001288648A1 (en) Methods and compositions for inhibiting angiogenesis

Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960307