IT1247533B - Processo per la separazione degli isomeri ottici di acidi carbossilici alfa-sostitutivi - Google Patents

Processo per la separazione degli isomeri ottici di acidi carbossilici alfa-sostitutivi

Info

Publication number
IT1247533B
IT1247533B ITMI911154A ITMI911154A IT1247533B IT 1247533 B IT1247533 B IT 1247533B IT MI911154 A ITMI911154 A IT MI911154A IT MI911154 A ITMI911154 A IT MI911154A IT 1247533 B IT1247533 B IT 1247533B
Authority
IT
Italy
Prior art keywords
alpha
separation
carboxylic acids
optical isomers
substitute
Prior art date
Application number
ITMI911154A
Other languages
English (en)
Inventor
Ezio Battistel
Daniele Bianchi
Pietro Cesti
Giuliana Franzosi
Roberto Tassinari
Sandro Spezia
Original Assignee
Mini Ricerca Scient Tecnolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mini Ricerca Scient Tecnolog filed Critical Mini Ricerca Scient Tecnolog
Priority to ITMI911154A priority Critical patent/IT1247533B/it
Publication of ITMI911154A0 publication Critical patent/ITMI911154A0/it
Priority to US07/872,108 priority patent/US5302528A/en
Priority to CA002066926A priority patent/CA2066926A1/en
Priority to JP04105064A priority patent/JP3140549B2/ja
Priority to EP19920107146 priority patent/EP0510712A3/xx
Publication of ITMI911154A1 publication Critical patent/ITMI911154A1/it
Application granted granted Critical
Publication of IT1247533B publication Critical patent/IT1247533B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/84—Brevibacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Si descrive il processo per la separazione degli isomeri ottici di acidi alfa-aril- o alfa-arilossi- carbossilici mediante idrolisi stereoselettiva di esteri alchilici racemi dei suddetti acidi in presenza di batteri o di loro enzimi, scelti nelle specie Brevibacterium, Bacteridium, Micrococcus e Bacillus.
ITMI911154A 1991-04-26 1991-04-26 Processo per la separazione degli isomeri ottici di acidi carbossilici alfa-sostitutivi IT1247533B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ITMI911154A IT1247533B (it) 1991-04-26 1991-04-26 Processo per la separazione degli isomeri ottici di acidi carbossilici alfa-sostitutivi
US07/872,108 US5302528A (en) 1991-04-26 1992-04-22 Process for the enzymatic separation of the optical isomers of alpha-substituted carboxylic acids using esterase from Brevibacterium imperiale
CA002066926A CA2066926A1 (en) 1991-04-26 1992-04-23 Process for the separation of the optical isomers of alphasubstituted carboxylic acids
JP04105064A JP3140549B2 (ja) 1991-04-26 1992-04-24 α−置換カルボン酸の光学異性体の分離法
EP19920107146 EP0510712A3 (en) 1991-04-26 1992-04-27 Process for the separation of the optical isomers of alpha-substituted carboxylic acids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911154A IT1247533B (it) 1991-04-26 1991-04-26 Processo per la separazione degli isomeri ottici di acidi carbossilici alfa-sostitutivi

Publications (3)

Publication Number Publication Date
ITMI911154A0 ITMI911154A0 (it) 1991-04-26
ITMI911154A1 ITMI911154A1 (it) 1992-10-26
IT1247533B true IT1247533B (it) 1994-12-17

Family

ID=11359788

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI911154A IT1247533B (it) 1991-04-26 1991-04-26 Processo per la separazione degli isomeri ottici di acidi carbossilici alfa-sostitutivi

Country Status (5)

Country Link
US (1) US5302528A (it)
EP (1) EP0510712A3 (it)
JP (1) JP3140549B2 (it)
CA (1) CA2066926A1 (it)
IT (1) IT1247533B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580783A (en) * 1994-10-12 1996-12-03 E. I. Du Pont De Nemours And Company Enzymatic process for the preparation of chiral α-tertiary carboxylic acid esters
US5599698A (en) * 1994-12-27 1997-02-04 Montefibre S.P.A. Modified materials based on polyacrylonitrile and process for their production
US5843765A (en) * 1997-01-31 1998-12-01 National Research Council Of Canada Streptomyces microorganism useful for the preparation of (R)-baclofen from the racemic mixture
IT1315212B1 (it) * 1999-07-26 2003-02-03 Consiglio Nazionale Ricerche Impiego di ortoesteri per la sintesi di acidi chirali in processi diesterificazione irreversibili biocatalizzati.
KR100378741B1 (ko) * 2000-06-01 2003-04-07 에스케이 주식회사 효소를 이용하여 R-폼 또는 S-폼의 α-치환 헤테로싸이클릭 카르복실산 및 이와 상반되는 광학특성을 갖는 α-치환 헤테로싸이클릭 카르복실산 에스테르를 제조하는 방법
DE60143262D1 (de) * 2000-06-01 2010-11-25 Sk Holdings Co Ltd Verfahren zur optischen auflösung einer razemischen alpha-substituierten, heterozyklischen karbonsäure unter enzymverwendung
US7217560B2 (en) * 2001-03-07 2007-05-15 Daiichi Pharmaceutical Co., Ltd. Process for preparation of optically active propoxyaniline derivatives
KR100846676B1 (ko) 2006-04-27 2008-07-16 엔자이텍 주식회사 효소적 방법에 의한 광학활성 2-할로-2-(엔-치환된페닐)아세트산 에스테르와 2-할로-2-(엔-치환된페닐)아세트산의 제조 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3345660A1 (de) * 1983-12-16 1985-06-27 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur gewinnung von d(+)naproxen
GB8600245D0 (en) * 1986-01-07 1986-02-12 Shell Int Research Preparation of 2-arylpropionic acids
JPS6363396A (ja) * 1986-09-05 1988-03-19 Nitto Chem Ind Co Ltd ｄ−２−（６−メトキシ−２−ナフチル）プロピオン酸の製造方法
US4800162A (en) * 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
GB8715476D0 (en) * 1987-07-01 1987-08-05 Shell Int Research Preparation of ibuprofen
JPH0636756B2 (ja) * 1988-01-26 1994-05-18 日東化学工業株式会社 光学活性カルボン酸及びその対掌体エステルの製造法
US5229280A (en) * 1988-02-25 1993-07-20 Istituto Guido Donegani S.P.A. Process for the continuous biotechnological preparation of optical isomer s(+) of 2-(6-methoxy-2-naphthyl) propionic acid
DE3919029A1 (de) * 1989-06-10 1990-12-13 Hoechst Ag Verfahren zur enzymatischen spaltung von 2-arylpropionsaeure-vinylester

Also Published As

Publication number Publication date
ITMI911154A0 (it) 1991-04-26
US5302528A (en) 1994-04-12
JPH05336991A (ja) 1993-12-21
JP3140549B2 (ja) 2001-03-05
ITMI911154A1 (it) 1992-10-26
EP0510712A3 (en) 1994-10-26
CA2066926A1 (en) 1992-10-27
EP0510712A2 (en) 1992-10-28

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Effective date: 19970415