IT1251961B - Peptidi che rappresentano permutazioni della sequenza del mastoparano - Google Patents
Peptidi che rappresentano permutazioni della sequenza del mastoparanoInfo
- Publication number
- IT1251961B IT1251961B ITMI912770A ITMI912770A IT1251961B IT 1251961 B IT1251961 B IT 1251961B IT MI912770 A ITMI912770 A IT MI912770A IT MI912770 A ITMI912770 A IT MI912770A IT 1251961 B IT1251961 B IT 1251961B
- Authority
- IT
- Italy
- Prior art keywords
- peptides
- mastoparan
- sequence
- permutations
- represent
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- MASXKPLGZRMBJF-MVSGICTGSA-N mastoparan Chemical group CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(N)=O MASXKPLGZRMBJF-MVSGICTGSA-N 0.000 title abstract 2
- 108091006027 G proteins Proteins 0.000 abstract 1
- 102000030782 GTP binding Human genes 0.000 abstract 1
- 108091000058 GTP-Binding Proteins 0.000 abstract 1
- 230000004075 alteration Effects 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 102000006240 membrane receptors Human genes 0.000 abstract 1
- 108020004084 membrane receptors Proteins 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Vengono descritti dei nuovi peptidi che rappresentano permutazioni della sequenza del mastoparano. I peptidi possono essere di interesse farmaceutico per contrastare patologie dovute ad alterazioni dell'interazione tra recettori di membrana e proteine G.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI912770A IT1251961B (it) | 1991-10-21 | 1991-10-21 | Peptidi che rappresentano permutazioni della sequenza del mastoparano |
| US07/961,837 US5519116A (en) | 1991-10-21 | 1992-10-16 | Peptides representing permutations of the mastoparan sequence |
| EP9292203174A EP0538942A3 (en) | 1991-10-21 | 1992-10-16 | Peptides representing permutations of the mastoparan sequence |
| JP4283201A JPH05213993A (ja) | 1991-10-21 | 1992-10-21 | マストパラン配列の順列を示すペプチド |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI912770A IT1251961B (it) | 1991-10-21 | 1991-10-21 | Peptidi che rappresentano permutazioni della sequenza del mastoparano |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI912770A0 ITMI912770A0 (it) | 1991-10-21 |
| ITMI912770A1 ITMI912770A1 (it) | 1993-04-21 |
| IT1251961B true IT1251961B (it) | 1995-05-27 |
Family
ID=11360903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI912770A IT1251961B (it) | 1991-10-21 | 1991-10-21 | Peptidi che rappresentano permutazioni della sequenza del mastoparano |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US5519116A (it) |
| EP (1) | EP0538942A3 (it) |
| JP (1) | JPH05213993A (it) |
| IT (1) | IT1251961B (it) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5726155A (en) * | 1993-08-02 | 1998-03-10 | The Scripps Research Institute | Regulation of oxidative burst using LMWG-derived peptides and analogs |
| WO2005072766A2 (en) * | 2004-01-27 | 2005-08-11 | Boys Town National Research Hospital | Peptides that bind to hsp90 proteins |
| WO2006049580A1 (en) * | 2004-11-04 | 2006-05-11 | National University Of Singapore | Anticoagulant peptides |
-
1991
- 1991-10-21 IT ITMI912770A patent/IT1251961B/it active IP Right Grant
-
1992
- 1992-10-16 EP EP9292203174A patent/EP0538942A3/en not_active Ceased
- 1992-10-16 US US07/961,837 patent/US5519116A/en not_active Expired - Fee Related
- 1992-10-21 JP JP4283201A patent/JPH05213993A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI912770A0 (it) | 1991-10-21 |
| ITMI912770A1 (it) | 1993-04-21 |
| EP0538942A2 (en) | 1993-04-28 |
| EP0538942A3 (en) | 1994-09-14 |
| JPH05213993A (ja) | 1993-08-24 |
| US5519116A (en) | 1996-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19951011 |