IT1254360B - Epitopi immunologicamente omologhi di hla e proteine del virus hiv. - Google Patents

Epitopi immunologicamente omologhi di hla e proteine del virus hiv.

Info

Publication number
IT1254360B
IT1254360B ITRM920350A ITRM920350A IT1254360B IT 1254360 B IT1254360 B IT 1254360B IT RM920350 A ITRM920350 A IT RM920350A IT RM920350 A ITRM920350 A IT RM920350A IT 1254360 B IT1254360 B IT 1254360B
Authority
IT
Italy
Prior art keywords
hla
immunologically
epitopes
homological
hiv proteins
Prior art date
Application number
ITRM920350A
Other languages
English (en)
Inventor
Alberto Beretta
Original Assignee
San Romanello Centro Fond
Ist Superiore Sanita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by San Romanello Centro Fond, Ist Superiore Sanita filed Critical San Romanello Centro Fond
Publication of ITRM920350A0 publication Critical patent/ITRM920350A0/it
Priority to ITRM920350A priority Critical patent/IT1254360B/it
Priority to US08/335,733 priority patent/US6042831A/en
Priority to AT93910325T priority patent/ATE188484T1/de
Priority to PCT/IT1993/000049 priority patent/WO1993023427A1/en
Priority to DE69327529T priority patent/DE69327529T2/de
Priority to EP93910325A priority patent/EP0641357B1/en
Priority to CA002135630A priority patent/CA2135630C/en
Publication of ITRM920350A1 publication Critical patent/ITRM920350A1/it
Application granted granted Critical
Publication of IT1254360B publication Critical patent/IT1254360B/it
Priority to US09/243,079 priority patent/US20020081566A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Sono descritti epitopi immunologicamente omologhi tra HLA e proteine di HIV, in particolare gp120, da utilizzarsi nella diagnostica e nella preparazione di vaccini.
ITRM920350A 1992-05-11 1992-05-11 Epitopi immunologicamente omologhi di hla e proteine del virus hiv. IT1254360B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ITRM920350A IT1254360B (it) 1992-05-11 1992-05-11 Epitopi immunologicamente omologhi di hla e proteine del virus hiv.
DE69327529T DE69327529T2 (de) 1992-05-11 1993-05-10 Immunologisch mit HLA homologe HIV Protein Epitope
AT93910325T ATE188484T1 (de) 1992-05-11 1993-05-10 Immunologisch mit hla homologe hiv protein epitope
PCT/IT1993/000049 WO1993023427A1 (en) 1992-05-11 1993-05-10 Hiv protein epitopes immunologically homologous to hla
US08/335,733 US6042831A (en) 1992-05-11 1993-05-10 Human immunodeficiency virus type 1 (HIV-1) GP160 epitopes that are immunologically homologous to epitopes located in the class I major histocompatibility complex (MHC) heavy chain α-1 domain
EP93910325A EP0641357B1 (en) 1992-05-11 1993-05-10 Hiv protein epitopes immunologically homologous to hla
CA002135630A CA2135630C (en) 1992-05-11 1993-05-10 Hiv protein epitopes immunologically homologous to hla
US09/243,079 US20020081566A1 (en) 1992-05-11 1999-02-02 Hiv protein epitopes immunologically homologous to hla

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM920350A IT1254360B (it) 1992-05-11 1992-05-11 Epitopi immunologicamente omologhi di hla e proteine del virus hiv.

Publications (3)

Publication Number Publication Date
ITRM920350A0 ITRM920350A0 (it) 1992-05-11
ITRM920350A1 ITRM920350A1 (it) 1993-11-11
IT1254360B true IT1254360B (it) 1995-09-14

Family

ID=11400995

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM920350A IT1254360B (it) 1992-05-11 1992-05-11 Epitopi immunologicamente omologhi di hla e proteine del virus hiv.

Country Status (7)

Country Link
US (2) US6042831A (it)
EP (1) EP0641357B1 (it)
AT (1) ATE188484T1 (it)
CA (1) CA2135630C (it)
DE (1) DE69327529T2 (it)
IT (1) IT1254360B (it)
WO (1) WO1993023427A1 (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1254360B (it) * 1992-05-11 1995-09-14 San Romanello Centro Fond Epitopi immunologicamente omologhi di hla e proteine del virus hiv.
IT1264078B1 (it) * 1993-09-10 1996-09-10 San Romanello Centro Fond Uso di anticorpi anti-molecole hla classe i libere da beta-2 microglobulina per saggi di evidenziazione dell'esposizione al virus
CN1339320A (zh) * 2000-08-18 2002-03-13 清华大学 一种艾滋病疫苗及其制备方法与应用
US7923209B2 (en) 2003-03-14 2011-04-12 Anergis, S.A. Allergen peptide fragments and use thereof
WO2011119920A2 (en) 2010-03-25 2011-09-29 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
SMT201800284T1 (it) 2011-06-10 2018-07-17 Univ Oregon Health & Science Glicoproteine cmv e vettori ricombinanti
EP2568289A3 (en) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
EP2586461A1 (en) 2011-10-27 2013-05-01 Christopher L. Parks Viral particles derived from an enveloped virus
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
EP2848937A1 (en) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Methods of identifying novel HIV-1 immunogens
EP2873423B1 (en) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
WO2017152144A1 (en) * 2016-03-03 2017-09-08 Duke University Swarm immunization with envelopes from ch505

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943628A (en) * 1988-06-13 1990-07-24 Ortho Pharmaceutical Corporation HIV peptide-inducted T cell stimulation
AU641814B2 (en) * 1990-09-25 1993-09-30 Peptech (Uk) Limited Aids therapy and vaccine
AU650911B2 (en) * 1990-09-27 1994-07-07 Syntello Vaccine Development Kb Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus
IT1254360B (it) * 1992-05-11 1995-09-14 San Romanello Centro Fond Epitopi immunologicamente omologhi di hla e proteine del virus hiv.

Also Published As

Publication number Publication date
ITRM920350A1 (it) 1993-11-11
DE69327529T2 (de) 2000-08-10
DE69327529D1 (de) 2000-02-10
US6042831A (en) 2000-03-28
EP0641357B1 (en) 2000-01-05
CA2135630A1 (en) 1993-11-25
US20020081566A1 (en) 2002-06-27
WO1993023427A1 (en) 1993-11-25
EP0641357A1 (en) 1995-03-08
ATE188484T1 (de) 2000-01-15
ITRM920350A0 (it) 1992-05-11
CA2135630C (en) 2005-03-22

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960419