IT1254452B - N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli - Google Patents

N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli

Info

Publication number
IT1254452B
IT1254452B ITMI920316A ITMI920316A IT1254452B IT 1254452 B IT1254452 B IT 1254452B IT MI920316 A ITMI920316 A IT MI920316A IT MI920316 A ITMI920316 A IT MI920316A IT 1254452 B IT1254452 B IT 1254452B
Authority
IT
Italy
Prior art keywords
piperazin
propan
diols
oxides
dioxides
Prior art date
Application number
ITMI920316A
Other languages
English (en)
Inventor
Roberto Giani
Carmelo A Gandolfi
Marco Mantovanini
Original Assignee
Dompe Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Farmaceutici Spa filed Critical Dompe Farmaceutici Spa
Priority to ITMI920316A priority Critical patent/IT1254452B/it
Publication of ITMI920316A0 publication Critical patent/ITMI920316A0/it
Priority to AU34961/93A priority patent/AU3496193A/en
Priority to PCT/EP1993/000307 priority patent/WO1993016056A1/en
Publication of ITMI920316A1 publication Critical patent/ITMI920316A1/it
Application granted granted Critical
Publication of IT1254452B publication Critical patent/IT1254452B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Si descrivono N-ossidi di 3-(4-aril-piperazin-1-il)-propan-1,2-dioli di interesse farmaceutico, in particolare come agenti antitosse.
ITMI920316A 1992-02-14 1992-02-14 N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli IT1254452B (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ITMI920316A IT1254452B (it) 1992-02-14 1992-02-14 N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli
AU34961/93A AU3496193A (en) 1992-02-14 1993-02-09 3-(piperazin-1-yl)-propane-1,2-diol N-oxydes and N,N'-dioxides
PCT/EP1993/000307 WO1993016056A1 (en) 1992-02-14 1993-02-09 3-(piperazin-1-yl)-propane-1,2-diol n-oxydes and n,n'-dioxides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI920316A IT1254452B (it) 1992-02-14 1992-02-14 N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli

Publications (3)

Publication Number Publication Date
ITMI920316A0 ITMI920316A0 (it) 1992-02-14
ITMI920316A1 ITMI920316A1 (it) 1993-08-14
IT1254452B true IT1254452B (it) 1995-09-25

Family

ID=11361965

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI920316A IT1254452B (it) 1992-02-14 1992-02-14 N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli

Country Status (3)

Country Link
AU (1) AU3496193A (it)
IT (1) IT1254452B (it)
WO (1) WO1993016056A1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1318651B1 (it) * 2000-07-28 2003-08-27 Dompe Spa Sintesi di (+-)1,3-diossolani e loro risoluzione ottica.
IT1318650B1 (it) * 2000-07-28 2003-08-27 Dompe Spa 1,3-diossolani ad attivita' antitosse.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE624723A (it) *
IT1203721B (it) * 1983-12-29 1989-02-23 Dompe Farmaceutici Spa Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono
NL8801622A (nl) * 1988-06-25 1990-01-16 Stamicarbon Bereiding van enantiomeren van dropropizine.
IT1217950B (it) * 1988-06-28 1990-03-30 Dott Formenti Ind Chimica E Fa Sali di (r,s) 3 (4 fenil 1 piperazinil) 1,2 propandtolo
IT1226570B (it) * 1988-08-01 1991-01-24 Bidachem Spa Procedimento di preparazione della levo- e destro-dropropizina
IT1231158B (it) * 1989-07-20 1991-11-19 Dompe Farmaceutici Spa Procedimento per la risoluzione ottica della dropropizina.

Also Published As

Publication number Publication date
ITMI920316A1 (it) 1993-08-14
AU3496193A (en) 1993-09-03
ITMI920316A0 (it) 1992-02-14
WO1993016056A1 (en) 1993-08-19

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