IT1255968B - Composizioni farmaceutiche contenenti acido ursodesossicolico - Google Patents

Composizioni farmaceutiche contenenti acido ursodesossicolico

Info

Publication number
IT1255968B
IT1255968B ITMI922721A ITMI922721A IT1255968B IT 1255968 B IT1255968 B IT 1255968B IT MI922721 A ITMI922721 A IT MI922721A IT MI922721 A ITMI922721 A IT MI922721A IT 1255968 B IT1255968 B IT 1255968B
Authority
IT
Italy
Prior art keywords
pharmaceutical compositions
compositions containing
acid
ursodesoxicolic
active ingredient
Prior art date
Application number
ITMI922721A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ITMI922721A priority Critical patent/IT1255968B/it
Publication of ITMI922721A0 publication Critical patent/ITMI922721A0/it
Priority to ES93118886T priority patent/ES2134237T3/es
Priority to AT93118886T priority patent/ATE180969T1/de
Priority to EP93118886A priority patent/EP0599282B1/en
Priority to DE69325236T priority patent/DE69325236T2/de
Publication of ITMI922721A1 publication Critical patent/ITMI922721A1/it
Application granted granted Critical
Publication of IT1255968B publication Critical patent/IT1255968B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invenzione è relativa a composizioni farmaceutiche contenenti l'acido ursodesossicolico come principio attivo in forma di microgranuli ottenuti mediante estrusione/sferonizzazione di una miscela di acido ursodesossicolico ed altri eccipienti di comune impiego: ciò permette un rilascio controllato del principio attivo.
ITMI922721A 1992-11-27 1992-11-27 Composizioni farmaceutiche contenenti acido ursodesossicolico IT1255968B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ITMI922721A IT1255968B (it) 1992-11-27 1992-11-27 Composizioni farmaceutiche contenenti acido ursodesossicolico
ES93118886T ES2134237T3 (es) 1992-11-27 1993-11-24 Composiciones farmaceuticas que contienen acido ursodesoxicolico.
AT93118886T ATE180969T1 (de) 1992-11-27 1993-11-24 Pharmazeutische zusammensetzungen enthaltend urodeoxycholicsäure
EP93118886A EP0599282B1 (en) 1992-11-27 1993-11-24 Pharmaceutical compositions containing ursodeoxycholic acid
DE69325236T DE69325236T2 (de) 1992-11-27 1993-11-24 Pharmazeutische Zusammensetzungen enthaltend Urodeoxycholicsäure

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI922721A IT1255968B (it) 1992-11-27 1992-11-27 Composizioni farmaceutiche contenenti acido ursodesossicolico

Publications (3)

Publication Number Publication Date
ITMI922721A0 ITMI922721A0 (it) 1992-11-27
ITMI922721A1 ITMI922721A1 (it) 1994-05-27
IT1255968B true IT1255968B (it) 1995-11-17

Family

ID=11364369

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI922721A IT1255968B (it) 1992-11-27 1992-11-27 Composizioni farmaceutiche contenenti acido ursodesossicolico

Country Status (5)

Country Link
EP (1) EP0599282B1 (it)
AT (1) ATE180969T1 (it)
DE (1) DE69325236T2 (it)
ES (1) ES2134237T3 (it)
IT (1) IT1255968B (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7772220B2 (en) 2004-10-15 2010-08-10 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
ITMI20012572A1 (it) * 2001-12-06 2003-06-06 Istituto Biochimico Italiano Microgranuli di acido ursodesossicolico
US7145125B2 (en) 2003-06-23 2006-12-05 Advanced Optical Technologies, Llc Integrating chamber cone light using LED sources
DE602005019582D1 (de) 2004-08-30 2010-04-08 Seo Hong Yoo Nervenschutzwirkung von aufgelöster udca bei einem fokalen ischämischen modell
KR20070084211A (ko) 2004-10-15 2007-08-24 유서홍 약제학적 화합물의 독성을 감소시키기 위한 방법 및 조성물
EP1819318A1 (en) * 2004-11-24 2007-08-22 Seo Hong Yoo Dried forms of aqueous solubilized bile acid dosage formulation
BRPI0810025A2 (pt) * 2007-04-19 2014-10-14 Disphar Int Bv Formulação farmacêutica oral de liberação imediata, método para preparar uma formulação farmacêutica multiparticulada, e, uso de ácido ursodesoxicólico
MX2009001925A (es) * 2009-02-20 2010-08-20 Senosiain S A De C V Lab Composicion farmaceutica oral para uso en enfermedades respiratorias.
ITTO20111064A1 (it) * 2011-11-18 2013-05-19 Abc Farmaceutici S P A Compresse a rilascio protratto, comprendenti acido ursodesossicolico
US20220304937A1 (en) * 2015-09-16 2022-09-29 Laboratoires C.T.R.S. Pediatric formulation
CN107095858B (zh) * 2017-06-27 2020-04-10 石家庄学院 一种熊去氧胆酸胶囊及其制备方法
CN107496928B (zh) * 2017-09-11 2020-07-14 石家庄学院 一种熊去氧胆酸干混悬剂及其制备方法
CA3142991A1 (fr) * 2019-06-28 2020-12-30 Tilman Composition comprenant un extrudat thermoforme d'au moins un triterpene et/ou au moins une de leurs formes glycosylees
CN110478304B (zh) * 2019-08-20 2022-07-05 广州市金熊大健康科技有限公司 一种含有熊胆微胶囊的牙膏
AU2023313512A1 (en) * 2022-07-25 2025-01-30 Shilpa Medicare Limited Pharmaceutical compositions of nor-udca

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0747539B2 (ja) * 1986-10-22 1995-05-24 東京田辺製薬株式会社 胆汁酸固形製剤
GB8722306D0 (en) * 1987-09-22 1987-10-28 Aps Research Ltd Sustained-release formulation
IT1245891B (it) * 1991-04-12 1994-10-25 Alfa Wassermann Spa Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali.
US5260074A (en) * 1992-06-22 1993-11-09 Digestive Care Inc. Compositions of digestive enzymes and salts of bile acids and process for preparation thereof

Also Published As

Publication number Publication date
DE69325236D1 (de) 1999-07-15
ATE180969T1 (de) 1999-06-15
EP0599282A1 (en) 1994-06-01
EP0599282B1 (en) 1999-06-09
ITMI922721A0 (it) 1992-11-27
ITMI922721A1 (it) 1994-05-27
ES2134237T3 (es) 1999-10-01
DE69325236T2 (de) 2000-01-27

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971128