IT1256023B - Derivati benzossazinonici e benzotiazinonici ad attivita' cardiovascolare - Google Patents

Derivati benzossazinonici e benzotiazinonici ad attivita' cardiovascolare

Info

Publication number
IT1256023B
IT1256023B ITMI921423A ITMI921423A IT1256023B IT 1256023 B IT1256023 B IT 1256023B IT MI921423 A ITMI921423 A IT MI921423A IT MI921423 A ITMI921423 A IT MI921423A IT 1256023 B IT1256023 B IT 1256023B
Authority
IT
Italy
Prior art keywords
benzothiazinonic
derivatives
benzossazinonic
cardiovascular activity
formula
Prior art date
Application number
ITMI921423A
Other languages
English (en)
Inventor
Silvio Levi
Francesca Benedini
Giorgio Bertolini
Giancarlo Dona
Gianni Gromo
Alberto Sala
Original Assignee
Italfarmaco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco Spa filed Critical Italfarmaco Spa
Priority to ITMI921423A priority Critical patent/IT1256023B/it
Publication of ITMI921423A0 publication Critical patent/ITMI921423A0/it
Priority to PCT/EP1993/001377 priority patent/WO1993025542A1/en
Publication of ITMI921423A1 publication Critical patent/ITMI921423A1/it
Application granted granted Critical
Publication of IT1256023B publication Critical patent/IT1256023B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/08—1,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Derivati benzossazinonici e benzotiazinonici di formula (I) (FORMULA I) dove Y è alchilene o cicloalchilene; R è idrogeno, alogeno, idrossi, alchile, nitro, sulfo, ciano, ammino, alcossi, formile, trifluorometile, ecc.; e X e Z sono indipendentemente S oppure O, e i loro sali, possiedono attività cardiovascolare.
ITMI921423A 1992-06-10 1992-06-10 Derivati benzossazinonici e benzotiazinonici ad attivita' cardiovascolare IT1256023B (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ITMI921423A IT1256023B (it) 1992-06-10 1992-06-10 Derivati benzossazinonici e benzotiazinonici ad attivita' cardiovascolare
PCT/EP1993/001377 WO1993025542A1 (en) 1992-06-10 1993-06-01 Benzoxazinone and benzothiazinone derivatives having cardiovascular activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI921423A IT1256023B (it) 1992-06-10 1992-06-10 Derivati benzossazinonici e benzotiazinonici ad attivita' cardiovascolare

Publications (3)

Publication Number Publication Date
ITMI921423A0 ITMI921423A0 (it) 1992-06-10
ITMI921423A1 ITMI921423A1 (it) 1993-12-10
IT1256023B true IT1256023B (it) 1995-11-20

Family

ID=11363482

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI921423A IT1256023B (it) 1992-06-10 1992-06-10 Derivati benzossazinonici e benzotiazinonici ad attivita' cardiovascolare

Country Status (2)

Country Link
IT (1) IT1256023B (it)
WO (1) WO1993025542A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19708846A1 (de) * 1997-03-05 1998-09-17 Gruenenthal Gmbh Neue Benzoxazindionderivate, Verfahren zu ihrer Herstellung und ihre Verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3047573A (en) * 1962-07-31 N-alkylamido substituted
US2714105A (en) * 1953-12-31 1955-07-26 American Cyanamid Co Benzoxazine diones and methods of preparing the same
CH459211A (de) * 1965-01-25 1968-07-15 Robapharm Ag Verfahren zur Herstellung von neuen basischen Derivaten des Dihydro-1,3-benzoxazin-2,4-dions
IT1244472B (it) * 1990-12-14 1994-07-15 Italfarmaco Spa Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare

Also Published As

Publication number Publication date
ITMI921423A0 (it) 1992-06-10
ITMI921423A1 (it) 1993-12-10
WO1993025542A1 (en) 1993-12-23

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960610