IT1256386B - Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo - Google Patents

Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo

Info

Publication number
IT1256386B
IT1256386B ITMI922603A ITMI922603A IT1256386B IT 1256386 B IT1256386 B IT 1256386B IT MI922603 A ITMI922603 A IT MI922603A IT MI922603 A ITMI922603 A IT MI922603A IT 1256386 B IT1256386 B IT 1256386B
Authority
IT
Italy
Prior art keywords
drug
oil
pharmaceutical compositions
cross
compositions including
Prior art date
Application number
ITMI922603A
Other languages
English (en)
Inventor
Luigi Boltri
Original Assignee
Luigi Boltri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luigi Boltri filed Critical Luigi Boltri
Priority to ITMI922603A priority Critical patent/IT1256386B/it
Publication of ITMI922603A0 publication Critical patent/ITMI922603A0/it
Priority to DE69324442T priority patent/DE69324442T2/de
Priority to ES93118278T priority patent/ES2132162T3/es
Priority to AT93118278T priority patent/ATE178787T1/de
Priority to EP93118278A priority patent/EP0598337B1/en
Publication of ITMI922603A1 publication Critical patent/ITMI922603A1/it
Application granted granted Critical
Publication of IT1256386B publication Critical patent/IT1256386B/it
Priority to US08/997,463 priority patent/US6107276A/en
Priority to GR990401811T priority patent/GR3030732T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Composizioni farmaceutiche contenenti un farmaco poco solubile incorporato in un polimero reticolato insolubile ma rigonfiabile in acqua, un agente tensioattivo e un olio presentano caratteristiche di dissoluzione e conseguentemente di biodisponibilità nettamente migliorate rispetto al farmaco tal quale e rispetto al farmaco supportato su detto polimero.
ITMI922603A 1992-11-13 1992-11-13 Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo IT1256386B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITMI922603A IT1256386B (it) 1992-11-13 1992-11-13 Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo
DE69324442T DE69324442T2 (de) 1992-11-13 1993-11-11 Arznei Zusammensetzungen, die ein Arzneimittel, ein quervernetztes Polymer, ein Öl, und ein grenzflächenaktives Mittel enthalten
ES93118278T ES2132162T3 (es) 1992-11-13 1993-11-11 Composiciones farmaceuticas que incluyen un farmaco, una sustancia polimerica reticulada, un aceite y un agente tensioactivo.
AT93118278T ATE178787T1 (de) 1992-11-13 1993-11-11 Arznei zusammensetzungen, die ein arzneimittel, ein quervernetztes polymer, ein öl, und ein grenzflächenaktives mittel enthalten
EP93118278A EP0598337B1 (en) 1992-11-13 1993-11-11 Pharmaceutical compositions including a drug, a cross-linked polymeric substance, an oil, and a surface active agent
US08/997,463 US6107276A (en) 1992-11-13 1997-12-23 Pharmaceutical compositions including a drug, a cross-linked polymeric substance, an oil, and a surface active agent
GR990401811T GR3030732T3 (en) 1992-11-13 1999-07-09 Pharmaceutical compositions including a drug, a cross-linked polymeric substance, an oil, and a surface active agent.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI922603A IT1256386B (it) 1992-11-13 1992-11-13 Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo

Publications (3)

Publication Number Publication Date
ITMI922603A0 ITMI922603A0 (it) 1992-11-13
ITMI922603A1 ITMI922603A1 (it) 1994-05-13
IT1256386B true IT1256386B (it) 1995-12-04

Family

ID=11364286

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI922603A IT1256386B (it) 1992-11-13 1992-11-13 Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo

Country Status (7)

Country Link
US (1) US6107276A (it)
EP (1) EP0598337B1 (it)
AT (1) ATE178787T1 (it)
DE (1) DE69324442T2 (it)
ES (1) ES2132162T3 (it)
GR (1) GR3030732T3 (it)
IT (1) IT1256386B (it)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL115445A (en) * 1994-10-17 1999-08-17 Akzo Nobel Nv Solid pharmaceutical compositions comprising low dosage active ingredient oil and excipient capable of binding water and their preparation
NL1003503C2 (nl) * 1996-07-04 1998-01-07 Negma Steba International Dev Farmaceutische samenstelling voor orale toediening.
HUP9603364A2 (hu) * 1996-12-06 1998-12-28 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Ipriflavont tartalmazó csonthiány pótlására szolgáló gyógyászati készítmény és eljárás előállítására
NZ314702A (en) * 1997-04-29 1998-07-28 Bernard Charles Sherman Pharmaceutical composition comprising a cyclosporin in a solvent system of acetylated monoglycerides and a surfactant and optionally a hydrophilic solvent
AR012627A1 (es) 1997-04-29 2000-11-08 Sherman Bernard Charles Pre-concentrado de emulsion que comprende una ciclosporina y monoglicerido acetilado
IT1293835B1 (it) * 1997-08-08 1999-03-10 Foscama Biomed Chim Farma Composizioni farmaceutiche orali in forma solida a cessione modulata contenenti nicorandil e procedimento per la loro preparazione
US6063762A (en) * 1997-12-05 2000-05-16 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition
DK1154759T3 (da) 1998-12-30 2008-12-08 Dexcel Ltd Dispergerbart koncentrat til indgift af cyclosporin
ATE307808T1 (de) * 1999-03-24 2005-11-15 Scherer Technologies Inc R P Pharmazeutische formulierungen mit verbesserter löslichkeit in wasser
NZ515911A (en) * 1999-06-04 2004-02-27 Alza Corp Implantable gel compositions and method of manufacture
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
DE10046541A1 (de) * 2000-09-19 2002-03-28 Knoll Ag Mechanisch stabile darreichungsformen, enthaltend Ubichinone
US6300377B1 (en) * 2001-02-22 2001-10-09 Raj K. Chopra Coenzyme Q products exhibiting high dissolution qualities
MXPA04000517A (es) * 2001-07-17 2006-03-03 Idemitsu Kosan Co Medicamentos profilacticos de ascitis para aves de corral.
FR2832065B1 (fr) 2001-11-13 2004-11-05 Besins Int Belgique Composition pharmaceutique a base de progesterone micronisee son procede de preparation et ses utilisations
CN101664411A (zh) * 2003-11-14 2010-03-10 味之素株式会社 苯丙氨酸衍生物的固体分散体或固体分散体医药制剂
US20070196396A1 (en) * 2004-02-11 2007-08-23 Rubicon Research Private Limited Controlled release pharmaceutical compositions with improved bioavailability
AU2007230716B2 (en) 2006-03-28 2012-05-03 Javelin Pharmaceuticals, Inc. Formulations of low dose diclofenac and beta-cyclodextrin
ES2382026T3 (es) 2007-09-27 2012-06-04 Wockhardt Limited Composiciones farmacéuticas autoemulsionantes de reína o diacereína
KR101907411B1 (ko) * 2010-03-12 2018-10-12 베르그 엘엘씨 코엔자임 Ｑ10(ＣｏＱ10)의 정맥내 제형 및 이의 사용 방법
IE20100799A1 (en) * 2010-12-22 2012-08-01 Eurand Pharmaceuticals Ltd Pharmaceutical composites of poorly water soluble drugs and polymers
CN107095863A (zh) 2011-06-17 2017-08-29 博格有限责任公司 可吸入药物组合物
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US9687475B1 (en) 2016-03-24 2017-06-27 Ezra Pharma Llc Extended release pharmaceutical formulations with controlled impurity levels
US9675585B1 (en) 2016-03-24 2017-06-13 Ezra Pharma Extended release pharmaceutical formulations
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US9931349B2 (en) 2016-04-01 2018-04-03 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3224619A1 (de) * 1981-07-14 1983-05-19 Freund Industrial Co., Ltd., Tokyo Orale pharmazeutische zusammensetzung
DE3270785D1 (en) * 1981-10-29 1986-05-28 Bayer Ag Process for preparing solid fast-releasing drug formulations of dihydropyridines
GB8403359D0 (en) * 1984-02-08 1984-03-14 Erba Farmitalia Pharmaceutical compositions
DE3524572A1 (de) * 1985-07-10 1987-01-15 Thomae Gmbh Dr K Feste arzneimittelformen zur peroralen anwendung enthaltend 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin und verfahren zu ihrer herstellung
DK0448091T3 (da) * 1990-03-23 1999-05-03 Yoshitomi Pharmaceutical Farmaceutisk præparat indeholdende et i ringe grad vandopløseligt medikament

Also Published As

Publication number Publication date
ITMI922603A0 (it) 1992-11-13
GR3030732T3 (en) 1999-11-30
ATE178787T1 (de) 1999-04-15
DE69324442T2 (de) 1999-08-05
EP0598337A3 (en) 1995-06-14
EP0598337B1 (en) 1999-04-14
DE69324442D1 (de) 1999-05-20
ITMI922603A1 (it) 1994-05-13
US6107276A (en) 2000-08-22
ES2132162T3 (es) 1999-08-16
EP0598337A2 (en) 1994-05-25

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971128