IT1257697B - N-acil derivati di aminoalcooli come agenti terapeutici attivi sull'edema neurogenico endoneurale a livello del nervo periferico. - Google Patents

N-acil derivati di aminoalcooli come agenti terapeutici attivi sull'edema neurogenico endoneurale a livello del nervo periferico.

Info

Publication number
IT1257697B
IT1257697B ITMI920979A ITMI920979A IT1257697B IT 1257697 B IT1257697 B IT 1257697B IT MI920979 A ITMI920979 A IT MI920979A IT MI920979 A ITMI920979 A IT MI920979A IT 1257697 B IT1257697 B IT 1257697B
Authority
IT
Italy
Prior art keywords
endoneural
level
therapeutic agents
neurogenic
peripheral nerve
Prior art date
Application number
ITMI920979A
Other languages
English (en)
Inventor
Valle Francesco Della
Silvana Lorenzi
Valle Federica Della
Original Assignee
Lifegroup Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifegroup Spa filed Critical Lifegroup Spa
Priority to ITMI920979A priority Critical patent/IT1257697B/it
Publication of ITMI920979A0 publication Critical patent/ITMI920979A0/it
Priority to CA002094548A priority patent/CA2094548A1/en
Priority to EP93106529A priority patent/EP0570714B1/en
Priority to DE69326188T priority patent/DE69326188T2/de
Priority to AT93106529T priority patent/ATE183921T1/de
Priority to JP5120412A priority patent/JPH0640897A/ja
Publication of ITMI920979A1 publication Critical patent/ITMI920979A1/it
Priority to US08/326,958 priority patent/US5679667A/en
Application granted granted Critical
Publication of IT1257697B publication Critical patent/IT1257697B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Medicinal Preparation (AREA)

Abstract

N-acil derivati d'aminoalcooli scelti tra la monoetanolamina e la dietanolamina come agenti terapeutici attivi nel controllo della degranulazione mastocitaria che si determina a seguito della loro attivazione e proliferazione indotta da una noxa di varia origine a livello del nervo periferico ed in conseguenza di ciò in grado di intervenire, inibendolo, sull'edema neurogenico endoneurale che s'instaura in queste condizioni patologiche.
ITMI920979A 1992-04-24 1992-04-24 N-acil derivati di aminoalcooli come agenti terapeutici attivi sull'edema neurogenico endoneurale a livello del nervo periferico. IT1257697B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITMI920979A IT1257697B (it) 1992-04-24 1992-04-24 N-acil derivati di aminoalcooli come agenti terapeutici attivi sull'edema neurogenico endoneurale a livello del nervo periferico.
CA002094548A CA2094548A1 (en) 1992-04-24 1993-04-21 Aminoalcohols-n-acylderivatives as therapeutical agents against the neurogenic endoneural oedema developing at the peripheral nerve
EP93106529A EP0570714B1 (en) 1992-04-24 1993-04-22 Use of aminoalcohol-N-acylderivatives for the manufacture of a medicament for the treatment of neurogenic endoneural oedema of the peripheral nerve
DE69326188T DE69326188T2 (de) 1992-04-24 1993-04-22 Verwendung von N-Acylderivaten von Aminoalkoholen zur Herstellung eines Arzneimittels zur Behandlung von neurogenen endoneuralen Ödemen der peripheren Nerven
AT93106529T ATE183921T1 (de) 1992-04-24 1993-04-22 Verwendung von n-acylderivaten von aminoalkoholen zur herstellung eines arzneimittels zur behandlung von neurogenen endoneuralen ödemen der peripheren nerven
JP5120412A JPH0640897A (ja) 1992-04-24 1993-04-26 末梢神経で発生する神経性神経内膜浮腫に対する治療剤としてのアミノアルコールｎアシル誘導体
US08/326,958 US5679667A (en) 1992-04-24 1994-10-21 Aminoalcohols-N-Acyl derivatives as therapeutical agents against the neurogenic endoneural edema of the peripheral nerve

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI920979A IT1257697B (it) 1992-04-24 1992-04-24 N-acil derivati di aminoalcooli come agenti terapeutici attivi sull'edema neurogenico endoneurale a livello del nervo periferico.

Publications (3)

Publication Number Publication Date
ITMI920979A0 ITMI920979A0 (it) 1992-04-24
ITMI920979A1 ITMI920979A1 (it) 1993-10-24
IT1257697B true IT1257697B (it) 1996-02-01

Family

ID=11363050

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI920979A IT1257697B (it) 1992-04-24 1992-04-24 N-acil derivati di aminoalcooli come agenti terapeutici attivi sull'edema neurogenico endoneurale a livello del nervo periferico.

Country Status (6)

Country Link
EP (1) EP0570714B1 (it)
JP (1) JPH0640897A (it)
AT (1) ATE183921T1 (it)
CA (1) CA2094548A1 (it)
DE (1) DE69326188T2 (it)
IT (1) IT1257697B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1271623B (it) * 1994-03-21 1997-06-04 Lifegroup Spa N-acilderivati di aminoalcoli con acidi monocarbossilici e bicarbossilici con attivita' neuroprotettiva nelle patologie neurologiche correlate ad eccitotossicita'
WO2001004083A1 (en) 1999-07-07 2001-01-18 Innovet Italia S.R.L. Covalent derivatives of alkanolamides of monocarboxylic and dicarboxylic acids functionally active on the cb2 cannabinoid receptor
DE60228713D1 (de) † 2001-07-18 2008-10-16 Unilever Nv Zusammensetzungen für die behandlung von haaren und/oder kopfhaut
JP5112876B2 (ja) * 2004-11-07 2013-01-09 エフ． ギルフォード ティモシー 還元型グルタチオン経口投与のためのリポソーム処方物
FI3177281T3 (fi) * 2014-08-08 2024-03-13 Ali Res S R L Rasvahappojen ja palmitoyylietanoliamidin seos käytettäväksi tulehduksellisten ja allergisten patologioiden hoitoon
US10350179B2 (en) 2015-06-04 2019-07-16 Raffaele Migliaccio Combination comprising palmitoylethanolamide (PEA) and lycopene for use in the treatment of inflammatory diseases
IT201600098984A1 (it) * 2016-10-03 2018-04-03 Pharmaxima S R L Composizione oftalmica comprendente palmitoiletanolammide e suo uso in oftalmologia

Also Published As

Publication number Publication date
EP0570714B1 (en) 1999-09-01
EP0570714A3 (en) 1994-12-28
ITMI920979A0 (it) 1992-04-24
ITMI920979A1 (it) 1993-10-24
EP0570714A2 (en) 1993-11-24
JPH0640897A (ja) 1994-02-15
DE69326188T2 (de) 2000-04-13
DE69326188D1 (de) 1999-10-07
CA2094548A1 (en) 1993-10-25
ATE183921T1 (de) 1999-09-15

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Effective date: 19970429