IT1258182B - Composizioni contenenti bafilomycina per l'inibizione di vacuolizzazione indotta da helicobacter pylori - Google Patents
Composizioni contenenti bafilomycina per l'inibizione di vacuolizzazione indotta da helicobacter pyloriInfo
- Publication number
- IT1258182B IT1258182B ITFI920167A ITFI920167A IT1258182B IT 1258182 B IT1258182 B IT 1258182B IT FI920167 A ITFI920167 A IT FI920167A IT FI920167 A ITFI920167 A IT FI920167A IT 1258182 B IT1258182 B IT 1258182B
- Authority
- IT
- Italy
- Prior art keywords
- vacuolization
- compositions containing
- helicobacter pylori
- bafilomycina
- inhibition induced
- Prior art date
Links
- 241000590002 Helicobacter pylori Species 0.000 title abstract 2
- 229940037467 helicobacter pylori Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000005764 inhibitory process Effects 0.000 title 1
- 229930192649 bafilomycin Natural products 0.000 abstract 1
- XDHNQDDQEHDUTM-UHFFFAOYSA-N bafliomycin A1 Natural products COC1C=CC=C(C)CC(C)C(O)C(C)C=C(C)C=C(OC)C(=O)OC1C(C)C(O)C(C)C1(O)OC(C(C)C)C(C)C(O)C1 XDHNQDDQEHDUTM-UHFFFAOYSA-N 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrane Compounds (AREA)
Abstract
Sono descritte composizioni contenenti bafilomycina capaci di inibire la vacuolizzazione cellulare indotto da Helicobacter pylori.
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITFI920167A IT1258182B (it) | 1992-08-12 | 1992-08-12 | Composizioni contenenti bafilomycina per l'inibizione di vacuolizzazione indotta da helicobacter pylori |
| EP93917786A EP0654999A1 (en) | 1992-08-12 | 1993-08-11 | Use of inhibitors of vacuolar-type h?+ atpases |
| CA002142313A CA2142313A1 (en) | 1992-08-12 | 1993-08-11 | Use of inhibitors of vacuolar-type h atpases |
| JP6505871A JPH08502725A (ja) | 1992-08-12 | 1993-08-11 | 液胞型h▲上+▼atpアーゼのインヒビターの使用 |
| PCT/EP1993/002149 WO1994004161A1 (en) | 1992-08-12 | 1993-08-11 | Use of inhibitors of vacuolar-type h+ atpases |
| AU47095/93A AU4709593A (en) | 1992-08-12 | 1993-08-11 | Use of inhibitors of vacuolar-type H+ atpases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITFI920167A IT1258182B (it) | 1992-08-12 | 1992-08-12 | Composizioni contenenti bafilomycina per l'inibizione di vacuolizzazione indotta da helicobacter pylori |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITFI920167A0 ITFI920167A0 (it) | 1992-08-12 |
| ITFI920167A1 ITFI920167A1 (it) | 1994-02-12 |
| IT1258182B true IT1258182B (it) | 1996-02-20 |
Family
ID=11350200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITFI920167A IT1258182B (it) | 1992-08-12 | 1992-08-12 | Composizioni contenenti bafilomycina per l'inibizione di vacuolizzazione indotta da helicobacter pylori |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0654999A1 (it) |
| JP (1) | JPH08502725A (it) |
| AU (1) | AU4709593A (it) |
| CA (1) | CA2142313A1 (it) |
| IT (1) | IT1258182B (it) |
| WO (1) | WO1994004161A1 (it) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2117490C (en) * | 1992-02-26 | 2009-01-06 | Timothy L. Cover | Purified vacuolating toxin from helicobacter pylori and methods to use same |
| US5859219A (en) * | 1992-02-26 | 1999-01-12 | Vanderbilt University | Purified vacuolating toxin from Helicobacter pylori and methods to use same |
| US5721349A (en) * | 1992-02-26 | 1998-02-24 | Vanderbilt University | Vacuolating toxin-deficient H. pylori |
| DE4442970A1 (de) * | 1994-12-02 | 1996-06-05 | Byk Gulden Lomberg Chem Fab | Screening-Modell |
| WO1996017066A1 (de) * | 1994-12-02 | 1996-06-06 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Screening-modell |
| WO2012045451A1 (en) | 2010-10-05 | 2012-04-12 | Ludwig-Maximilians-Universitaet Muenchen | Novel therapeutic treatment of progranulin-dependent diseases |
| CN113286582B (zh) * | 2019-01-18 | 2025-01-10 | 国立研究开发法人科学技术振兴机构 | V-ATPase活性抑制剂、抗菌剂、药物以及抗菌方法和筛选方法 |
-
1992
- 1992-08-12 IT ITFI920167A patent/IT1258182B/it active IP Right Grant
-
1993
- 1993-08-11 CA CA002142313A patent/CA2142313A1/en not_active Abandoned
- 1993-08-11 WO PCT/EP1993/002149 patent/WO1994004161A1/en not_active Ceased
- 1993-08-11 EP EP93917786A patent/EP0654999A1/en not_active Withdrawn
- 1993-08-11 AU AU47095/93A patent/AU4709593A/en not_active Abandoned
- 1993-08-11 JP JP6505871A patent/JPH08502725A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ITFI920167A1 (it) | 1994-02-12 |
| EP0654999A1 (en) | 1995-05-31 |
| WO1994004161A1 (en) | 1994-03-03 |
| CA2142313A1 (en) | 1994-03-03 |
| ITFI920167A0 (it) | 1992-08-12 |
| AU4709593A (en) | 1994-03-15 |
| JPH08502725A (ja) | 1996-03-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69408460D1 (de) | Hochreine fluorelastomerzusammensetzungen | |
| GR1002038B (en) | Laparascopic instrument for the application of endoligatures. | |
| HU9302762D0 (en) | N-sulfonyl-2-oxoindole derivatives being effective on vasopressin and/or oxitocin receptors | |
| IL129768A0 (en) | Antithrombotic organic nitrates | |
| IL111314A (en) | Pharmaceutical compositions containing indole derivatives | |
| GB9225659D0 (en) | Stabilized pharmaceutical compositions comprising an hmg-coa-reductase inhibitor compound | |
| DE69413237D1 (en) | Plättchenaggregationsinhibitoren | |
| ZA975727B (en) | Inhibitors of prenyl transferases. | |
| DK537389D0 (da) | Glycosidase-inhibitoren salbostatin, dens fremstilling og anvendelse | |
| FI943817A7 (fi) | Bisyklo/2.2.2/oktaanijohdannaisia kolestokystokiniinin inhibiittoreina | |
| AU1430492A (en) | Pharmaceutical composition for the treatment of gastritis | |
| JO1704B1 (en) | New potent compounds | |
| PH31395A (en) | Bis-naphthalimides for the treatment of cancer. | |
| IL101245A0 (en) | Pharmaceutical compositions for the treatment of prostatic cancer | |
| IT1258182B (it) | Composizioni contenenti bafilomycina per l'inibizione di vacuolizzazione indotta da helicobacter pylori | |
| HU9400726D0 (en) | Film-forming compositions containing iodo-phenoxy-alkylen-ether derivatives for visualizing the gastrointes tinal tract | |
| AP9400632A0 (en) | Ether derivatives. | |
| GB2251617B (en) | Pharmaceutical compositions containing substituted 3-hydroxypyridin-4-ones | |
| ITTO910541A0 (it) | Rivestimento impermeabilizzante, particolarmente per l'eliminazione diinfiltrazioni | |
| GB8814422D0 (en) | Analgesic compounds & compositions | |
| TW330933B (en) | Furanoeremophilane and eremophilanolide sesquiterpenes for treatment of diabetes | |
| IL98405A0 (en) | Pharmaceutical compositions containing enzyme inhibiting agents | |
| IL110780A0 (en) | Pharmaceutical compositions containing 1,3-bis(2-carboxy-chromon-5-yloxy)-propan-2-ol for the treatment of the common cold | |
| AU2358592A (en) | Regioselective synthesis of 1,5-diarylpyrazole anti-inflammatory agents | |
| GB2283677B (en) | Liquid anthelmintic selenium compositions |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970827 |