IT1260153B - Individuazione di un frammento di dna codificante l'enzima acido ialuronico sintetasi (has) e della sua sequenza nucleotidica - Google Patents

Individuazione di un frammento di dna codificante l'enzima acido ialuronico sintetasi (has) e della sua sequenza nucleotidica

Info

Publication number
IT1260153B
IT1260153B ITPD920110A ITPD920110A IT1260153B IT 1260153 B IT1260153 B IT 1260153B IT PD920110 A ITPD920110 A IT PD920110A IT PD920110 A ITPD920110 A IT PD920110A IT 1260153 B IT1260153 B IT 1260153B
Authority
IT
Italy
Prior art keywords
identification
hyaluronic acid
dna fragment
acid synthetase
fragment coding
Prior art date
Application number
ITPD920110A
Other languages
English (en)
Inventor
Michael O'regan
Lanfranco Callegaro
Original Assignee
Michael O'regan
Lanfranco Callegaro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michael O'regan, Lanfranco Callegaro filed Critical Michael O'regan
Priority to ITPD920110A priority Critical patent/IT1260153B/it
Publication of ITPD920110A0 publication Critical patent/ITPD920110A0/it
Priority to PCT/EP1993/001575 priority patent/WO1994000463A2/en
Publication of ITPD920110A1 publication Critical patent/ITPD920110A1/it
Application granted granted Critical
Publication of IT1260153B publication Critical patent/IT1260153B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente invenzione si riferisce all'individuazione di un frammento di DNA codificante per l'enzima acido ialuronico sintetasi (HAS) di Streptococcus equisimilis D181, alla sequenza nucleotidica di questo frammento e all'impiego industriale di questo materiale.
ITPD920110A 1992-06-19 1992-06-19 Individuazione di un frammento di dna codificante l'enzima acido ialuronico sintetasi (has) e della sua sequenza nucleotidica IT1260153B (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ITPD920110A IT1260153B (it) 1992-06-19 1992-06-19 Individuazione di un frammento di dna codificante l'enzima acido ialuronico sintetasi (has) e della sua sequenza nucleotidica
PCT/EP1993/001575 WO1994000463A2 (en) 1992-06-19 1993-06-21 Production of hyaluronic acid by transeformed microorganisms

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITPD920110A IT1260153B (it) 1992-06-19 1992-06-19 Individuazione di un frammento di dna codificante l'enzima acido ialuronico sintetasi (has) e della sua sequenza nucleotidica

Publications (3)

Publication Number Publication Date
ITPD920110A0 ITPD920110A0 (it) 1992-06-19
ITPD920110A1 ITPD920110A1 (it) 1993-12-19
IT1260153B true IT1260153B (it) 1996-03-28

Family

ID=11389978

Family Applications (1)

Application Number Title Priority Date Filing Date
ITPD920110A IT1260153B (it) 1992-06-19 1992-06-19 Individuazione di un frammento di dna codificante l'enzima acido ialuronico sintetasi (has) e della sua sequenza nucleotidica

Country Status (2)

Country Link
IT (1) IT1260153B (it)
WO (1) WO1994000463A2 (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455304B1 (en) 1994-07-01 2002-09-24 The Board Of Regents Of The University Of Oklahoma Hyaluronate synthase gene and uses thereof
US6951743B2 (en) 1997-10-31 2005-10-04 University Of Oklahoma Board Of Regents Hyaluronan synthase genes and expression thereof in bacillus hosts
US7091008B1 (en) 1994-07-01 2006-08-15 The Board Of Regents Of The University Of Oklahoma Hyaluronan synthase genes and expression thereof in Bacillus hosts
US6423514B1 (en) * 1996-04-22 2002-07-23 Millennium Pharmaceuticals, Inc. Mammalian hyaluronan synthases, nucleic acids and uses thereof
DE69828193T2 (de) 1997-10-31 2005-12-01 The Board Of Regents Of The University Of Oklahoma, Norman Hyaluronan synthase gen und seine verwendung
CN101113436B (zh) 1997-10-31 2013-02-06 俄克拉何马大学董事会 透明质酸合酶基因及其应用
US6987023B2 (en) 1998-04-02 2006-01-17 The Board Of Regents Of The University Of Oklahoma DNA encoding hyaluronan synthase from Pasteurella multocida and methods of use
US20060188966A1 (en) 1998-04-02 2006-08-24 Deangelis Paul L Natural, chimeric and hybrid glycosaminoglycan polymers and methods of making and using same
US7223571B2 (en) 1998-04-02 2007-05-29 The Board Of Regents Of The Universtiy Of Oklahoma Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
BR9909346A (pt) * 1998-04-02 2001-09-11 Univ Oklahoma Segmento de ácido nucleico, vetor recombinante, célula hospedeira, composição, processos para detectar uma espécie de dna, uma célula bacteriana e infecção, para produzir ácido hialurÈnico e para criar uma vacina, sequência de ácido nucleico e de cdna, vacina e teste diagnóstico
US7094581B2 (en) 1998-10-26 2006-08-22 The Board Of Regents Of The University Of Oklahoma Hyaluronan synthases and methods of making and using same
KR101322227B1 (ko) * 2011-09-30 2013-10-28 일동제약주식회사 스트렙토코커스 디스갈락티애 ｉｄ9103 균주 및 이를 이용한 히알루론산 생산 방법
WO2013116819A1 (en) * 2012-02-03 2013-08-08 University Of Rochester Compositions and methods for recombinant synthesis of high molecular weight hyaluronic acid
CN119020314A (zh) * 2024-09-30 2024-11-26 海南省深海技术创新中心 一种透明质酸合成酶及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015577A (en) * 1989-08-29 1991-05-14 Board Of Regents, The University Of Texas System DNA encoding hyaluronate synthase

Also Published As

Publication number Publication date
ITPD920110A1 (it) 1993-12-19
WO1994000463A2 (en) 1994-01-06
ITPD920110A0 (it) 1992-06-19
WO1994000463A3 (en) 1994-09-29

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19990614