IT1261493B - Biosensore a matrice porosa ad elevatissima sensibilita' e procedimento per detto. - Google Patents
Biosensore a matrice porosa ad elevatissima sensibilita' e procedimento per detto.Info
- Publication number
- IT1261493B IT1261493B ITRM930512A ITRM930512A IT1261493B IT 1261493 B IT1261493 B IT 1261493B IT RM930512 A ITRM930512 A IT RM930512A IT RM930512 A ITRM930512 A IT RM930512A IT 1261493 B IT1261493 B IT 1261493B
- Authority
- IT
- Italy
- Prior art keywords
- matrix
- electrode
- bioelement
- conducting material
- mediator
- Prior art date
Links
- 239000011159 matrix material Substances 0.000 title abstract 4
- 230000035945 sensitivity Effects 0.000 title abstract 2
- 239000004020 conductor Substances 0.000 abstract 2
- 239000007772 electrode material Substances 0.000 abstract 2
- 229920000936 Agarose Polymers 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 abstract 1
- 230000003321 amplification Effects 0.000 abstract 1
- 239000012491 analyte Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000006260 foam Substances 0.000 abstract 1
- 229910002804 graphite Inorganic materials 0.000 abstract 1
- 239000010439 graphite Substances 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 229910052709 silver Inorganic materials 0.000 abstract 1
- 239000004332 silver Substances 0.000 abstract 1
Landscapes
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
Biosensore costituito essenzialmente da una matrice elettronica (1) porosa ad elevata superficie, grafite reticolata, spugna d'argento, ecc., in intimo contatto con una matrice altamente idrofilica come destrano o agarosio, su cui è immobilizzato fisicamente o chimicamente un bioelemento (2) enzima, recettore, ecc. Tale matrice può contenere un sistema mediatore. Al materiale conduttore è imposto un potenziale di lavoro compreso fra -1,5 e +1,5, rispetto ad un elettrodo di riferimento atto a permettere lo scambio di elettroni fra i composti elettroattivi generali, nella interazione analita-bioelemento-mediatore ed il materiale conduttore. Il materiale elettrodico permette di ottenere correnti elevate che si traducono in un aumento della sensibilità di alcuni ordini di grandezza in più, rispetto ai migliori biosensori a membrana, e la realizzazione di microsensori che non richiedono un sofisticato sistema di amplificazione elettrodica. Il materiale elettrodico, inserito in adatte configurazioni, può essere impiegato nel campo della diagnostica clinica o nelle misure in campi o sistemi di flusso.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM930512A IT1261493B (it) | 1993-07-30 | 1993-07-30 | Biosensore a matrice porosa ad elevatissima sensibilita' e procedimento per detto. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM930512A IT1261493B (it) | 1993-07-30 | 1993-07-30 | Biosensore a matrice porosa ad elevatissima sensibilita' e procedimento per detto. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITRM930512A0 ITRM930512A0 (it) | 1993-07-30 |
| ITRM930512A1 ITRM930512A1 (it) | 1995-01-30 |
| IT1261493B true IT1261493B (it) | 1996-05-23 |
Family
ID=11401892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITRM930512A IT1261493B (it) | 1993-07-30 | 1993-07-30 | Biosensore a matrice porosa ad elevatissima sensibilita' e procedimento per detto. |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1261493B (it) |
-
1993
- 1993-07-30 IT ITRM930512A patent/IT1261493B/it active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ITRM930512A1 (it) | 1995-01-30 |
| ITRM930512A0 (it) | 1993-07-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5272087A (en) | Enzymatic electrode and its preparation method | |
| US4356074A (en) | Substrate specific galactose oxidase enzyme electrodes | |
| Hoa et al. | A biosensor based on conducting polymers | |
| Santandreu et al. | Amperometric immunosensors based on rigid conducting immunocomposites | |
| JP3513260B2 (ja) | 電流測定電極及びそれを製造する方法 | |
| US6033866A (en) | Highly sensitive amperometric bi-mediator-based glucose biosensor | |
| AU2001283921A1 (en) | Disposable electrochemical bio-sensor for the quantitative determination of analyte concentrations in fluids | |
| Myler et al. | Poly (o-phenylenediamine) ultra-thin polymer-film composite membranes for enzyme electrodes | |
| DE69712866D1 (de) | Bestimmung eines analyten in einer probeflüssigkeit | |
| JPH0634596A (ja) | 酸素電極、バイオセンサ、及び、その製造方法 | |
| ATE242477T1 (de) | Elektrochemisches verfahren | |
| AU6157898A (en) | Small volume (in vitro) analyte sensor | |
| CA2358464A1 (en) | Disposable test strips with integrated reagent/blood separation layer | |
| EP0984069A3 (en) | Biosensor with an interferant detecting electrode | |
| Wang et al. | Tissue bioelectrode for organic-phase enzymatic assays | |
| EP0250068B1 (en) | Enzyme sensor | |
| JP3393361B2 (ja) | バイオセンサ | |
| Wang et al. | Microfabricated phenol biosensors based on screen printing of tyrosinase containing carbon ink | |
| Kampfrath et al. | Plasma-polymerized thin films for enzyme immobilization in biosensors | |
| Hill et al. | Enzyme dual-electrode for analyte determination | |
| JP2977258B2 (ja) | バイオセンサ | |
| Marcinkeviciene et al. | Bienzyme strip-type glucose sensor | |
| Phadke | Biosensors and enzyme immobilized electrodes | |
| Sethi et al. | Electrochemical microbiosensors | |
| GR1003489B (el) | Μεθοδος προσδιορισμου βιολογικων και χημικων παραγοντων μεσω της μετρησης των μεταβολων των ηλεκτρικων ιδιοτητων ακινητοποιημενων κυτταρων ή συστατικων αυτων (βιοηλεκτρικη μεθοδος αναγνωρισης) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960723 |