IT1264535B1 - Tioazasteroidi,loro uso come antiandrogeni e composizioni farmaceutiche che li contengono - Google Patents
Tioazasteroidi,loro uso come antiandrogeni e composizioni farmaceutiche che li contengonoInfo
- Publication number
- IT1264535B1 IT1264535B1 IT93MI001730A ITMI931730A IT1264535B1 IT 1264535 B1 IT1264535 B1 IT 1264535B1 IT 93MI001730 A IT93MI001730 A IT 93MI001730A IT MI931730 A ITMI931730 A IT MI931730A IT 1264535 B1 IT1264535 B1 IT 1264535B1
- Authority
- IT
- Italy
- Prior art keywords
- thioazasteroids
- antiandrogens
- pharmaceutical compositions
- compositions containing
- compounds
- Prior art date
Links
- 230000002280 anti-androgenic effect Effects 0.000 title 1
- 239000000051 antiandrogen Substances 0.000 title 1
- 229940030495 antiandrogen sex hormone and modulator of the genital system Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 108010029908 3-oxo-5-alpha-steroid 4-dehydrogenase Proteins 0.000 abstract 1
- 102000001779 3-oxo-5-alpha-steroid 4-dehydrogenase Human genes 0.000 abstract 1
- 239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Landscapes
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Sono descritti composti di formula generale (A): (FORMULA A) nella quale il legame carbonio-carbonio nelle posizioni 1-2 può essere semplice o doppio; X, RI, RII e RIII hanno i significati descritti di seguito. Questi composti sono dotati di attività inibitrice della 5-?-riduttasi del testosterone.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT93MI001730A IT1264535B1 (it) | 1993-07-30 | 1993-07-30 | Tioazasteroidi,loro uso come antiandrogeni e composizioni farmaceutiche che li contengono |
| PCT/EP1993/003400 WO1994013691A1 (en) | 1992-12-10 | 1993-12-03 | Thio- and oxo-azasteroids, processes for the preparation thereof, use thereof as antiandrogens and pharmaceutical compositions containing them |
| AU56955/94A AU5695594A (en) | 1992-12-10 | 1993-12-03 | Thio- and oxo-azasteroids, processes for the preparation thereof, use thereof as antiandrogens and pharmaceutical compositions containing them |
| IL10790393A IL107903A0 (en) | 1992-12-10 | 1993-12-06 | Thio- and oxo-azasteroids, processes for the preparation thereof, use thereof as antiandrogens and pharmaceutical compositions containing them |
| MX9307794A MX9307794A (es) | 1992-12-10 | 1993-12-09 | Tio-y oxo-azasteroides, proceso para su preparacion y composicion farmaceutica que los contiene. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT93MI001730A IT1264535B1 (it) | 1993-07-30 | 1993-07-30 | Tioazasteroidi,loro uso come antiandrogeni e composizioni farmaceutiche che li contengono |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI931730A0 ITMI931730A0 (it) | 1993-07-30 |
| ITMI931730A1 ITMI931730A1 (it) | 1995-01-30 |
| IT1264535B1 true IT1264535B1 (it) | 1996-10-02 |
Family
ID=11366746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT93MI001730A IT1264535B1 (it) | 1992-12-10 | 1993-07-30 | Tioazasteroidi,loro uso come antiandrogeni e composizioni farmaceutiche che li contengono |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1264535B1 (it) |
-
1993
- 1993-07-30 IT IT93MI001730A patent/IT1264535B1/it active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI931730A1 (it) | 1995-01-30 |
| ITMI931730A0 (it) | 1993-07-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970729 |