IT1265256B1 - 4-alchil e 4-alchenil delta-3-cefem solfoni - Google Patents
4-alchil e 4-alchenil delta-3-cefem solfoniInfo
- Publication number
- IT1265256B1 IT1265256B1 IT93MI002568A ITMI932568A IT1265256B1 IT 1265256 B1 IT1265256 B1 IT 1265256B1 IT 93MI002568 A IT93MI002568 A IT 93MI002568A IT MI932568 A ITMI932568 A IT MI932568A IT 1265256 B1 IT1265256 B1 IT 1265256B1
- Authority
- IT
- Italy
- Prior art keywords
- solfoni
- alchil
- alchenil
- cefem
- delta
- Prior art date
Links
- 125000000962 organic group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 102000016387 Pancreatic elastase Human genes 0.000 abstract 1
- 108010067372 Pancreatic elastase Proteins 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
Vengono descritti i composti di formula I (FORMULA I) in cui A è un gruppo organico, B è un atomo di idrogeno o di alogeno o un gruppo organico, R1 e R2 sono atomi di alogeno o un gruppo organico.I composti I sono inibitori dell'elastasi. Viene descritto anche un procedimento per la loro preparazione, come anche composizioni farmaceutiche che li contengono.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9225371A GB2273097B (en) | 1992-12-04 | 1992-12-04 | 4-Alkyl and 4-alkenyl delta-3-cephem sulphone human leukocyte elastase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI932568A0 ITMI932568A0 (it) | 1993-12-03 |
| ITMI932568A1 ITMI932568A1 (it) | 1995-06-03 |
| IT1265256B1 true IT1265256B1 (it) | 1996-10-31 |
Family
ID=10726119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT93MI002568A IT1265256B1 (it) | 1992-12-04 | 1993-12-03 | 4-alchil e 4-alchenil delta-3-cefem solfoni |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPH06228152A (it) |
| DE (1) | DE4341332A1 (it) |
| GB (1) | GB2273097B (it) |
| IT (1) | IT1265256B1 (it) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11511463A (ja) * | 1995-08-31 | 1999-10-05 | スミスクライン・ビーチャム・コーポレイション | インターロイキン変換酵素およびアポプトーシス |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8808701D0 (en) * | 1988-04-13 | 1988-05-18 | Erba Carlo Spa | Beta-lactam derivatives |
-
1992
- 1992-12-04 GB GB9225371A patent/GB2273097B/en not_active Expired - Fee Related
-
1993
- 1993-12-03 JP JP5304221A patent/JPH06228152A/ja active Pending
- 1993-12-03 DE DE4341332A patent/DE4341332A1/de not_active Withdrawn
- 1993-12-03 IT IT93MI002568A patent/IT1265256B1/it active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| GB9225371D0 (en) | 1993-01-27 |
| ITMI932568A1 (it) | 1995-06-03 |
| JPH06228152A (ja) | 1994-08-16 |
| GB2273097B (en) | 1996-09-18 |
| GB2273097A (en) | 1994-06-08 |
| DE4341332A1 (de) | 1994-06-09 |
| ITMI932568A0 (it) | 1993-12-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971125 |