IT1273987B - Uso di esteri ftalidilidenici della carnitina e di alcanoil carnitine per il trattamento dello shock endotossico - Google Patents

Uso di esteri ftalidilidenici della carnitina e di alcanoil carnitine per il trattamento dello shock endotossico

Info

Publication number
IT1273987B
IT1273987B ITRM940625A ITRM940625A IT1273987B IT 1273987 B IT1273987 B IT 1273987B IT RM940625 A ITRM940625 A IT RM940625A IT RM940625 A ITRM940625 A IT RM940625A IT 1273987 B IT1273987 B IT 1273987B
Authority
IT
Italy
Prior art keywords
carnitine
esters
phtalidyliden
alcanoyl
endotoxic shock
Prior art date
Application number
ITRM940625A
Other languages
English (en)
Inventor
Vito Ruggiero
Piero Foresta
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Priority to ITRM940625A priority Critical patent/IT1273987B/it
Publication of ITRM940625A0 publication Critical patent/ITRM940625A0/it
Priority to EP95830373A priority patent/EP0706793A3/en
Priority to US08/530,581 priority patent/US5814661A/en
Priority to JP7250853A priority patent/JPH08183734A/ja
Publication of ITRM940625A1 publication Critical patent/ITRM940625A1/it
Application granted granted Critical
Publication of IT1273987B publication Critical patent/IT1273987B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)

Abstract

Viene descritto l'uso di esteri (3-ftalidilidene) alchilici della carnitina e di alcanoil carnitine per produrre composizioni farmaceutiche atte al trattamento dello shock endotossico.
ITRM940625A 1994-09-29 1994-09-29 Uso di esteri ftalidilidenici della carnitina e di alcanoil carnitine per il trattamento dello shock endotossico IT1273987B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ITRM940625A IT1273987B (it) 1994-09-29 1994-09-29 Uso di esteri ftalidilidenici della carnitina e di alcanoil carnitine per il trattamento dello shock endotossico
EP95830373A EP0706793A3 (en) 1994-09-29 1995-09-08 Use of phthalidylidene esters of carnitine and alkanoyl carnitides for the treatment of endotoxic shock
US08/530,581 US5814661A (en) 1994-09-29 1995-09-19 Use of Phthalidyliden esters of carnitine and alkanoyl carnitines for the treatment of endotoxic shock
JP7250853A JPH08183734A (ja) 1994-09-29 1995-09-28 内毒素ショックの処置へのカルニチンおよびアルカノイルカルニチン類のフタリジリデンエステル類の使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM940625A IT1273987B (it) 1994-09-29 1994-09-29 Uso di esteri ftalidilidenici della carnitina e di alcanoil carnitine per il trattamento dello shock endotossico

Publications (3)

Publication Number Publication Date
ITRM940625A0 ITRM940625A0 (it) 1994-09-29
ITRM940625A1 ITRM940625A1 (it) 1996-03-29
IT1273987B true IT1273987B (it) 1997-07-14

Family

ID=11402748

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM940625A IT1273987B (it) 1994-09-29 1994-09-29 Uso di esteri ftalidilidenici della carnitina e di alcanoil carnitine per il trattamento dello shock endotossico

Country Status (4)

Country Link
US (1) US5814661A (it)
EP (1) EP0706793A3 (it)
JP (1) JPH08183734A (it)
IT (1) IT1273987B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1306129B1 (it) * 1999-04-13 2001-05-30 Sigma Tau Ind Farmaceuti Esteri della l-carnitina o di alcanoil l-carnitine utilizzabili comelipidi cationici per l'immissione intracellulare di composti
US10330685B2 (en) 2014-05-01 2019-06-25 The Regents Of The University Of Michigan Markers for sepsis treatment
US12478603B2 (en) 2020-03-31 2025-11-25 The Regents Of The University Of Michigan Serum metabolites as biomarkers for carnitine treatment of sepsis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045518A (ja) * 1983-08-22 1985-03-12 Takeda Chem Ind Ltd 抗シヨツク剤
IT1242020B (it) 1990-11-20 1994-02-02 Sigma Tau Ind Farmaceuti Ftalidilidene derivati della carnitina e di alcanoil carnitine e composizioni farmaceutiche che li contengono.

Also Published As

Publication number Publication date
EP0706793A2 (en) 1996-04-17
US5814661A (en) 1998-09-29
JPH08183734A (ja) 1996-07-16
EP0706793A3 (en) 1996-06-26
ITRM940625A0 (it) 1994-09-29
ITRM940625A1 (it) 1996-03-29

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970709