IT1303736B1 - Peptidi derivati da rantes con attivita' anti-hiv. - Google Patents

Peptidi derivati da rantes con attivita' anti-hiv.

Info

Publication number
IT1303736B1
IT1303736B1 IT1998MI002441A ITMI982441A IT1303736B1 IT 1303736 B1 IT1303736 B1 IT 1303736B1 IT 1998MI002441 A IT1998MI002441 A IT 1998MI002441A IT MI982441 A ITMI982441 A IT MI982441A IT 1303736 B1 IT1303736 B1 IT 1303736B1
Authority
IT
Italy
Prior art keywords
rantes
peptides derived
hiv activity
hiv
activity
Prior art date
Application number
IT1998MI002441A
Other languages
English (en)
Inventor
Paolo Lusso
Vincenzo Pavone
Original Assignee
San Raffaele Centro Fond
Primm Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by San Raffaele Centro Fond, Primm Srl filed Critical San Raffaele Centro Fond
Priority to IT1998MI002441A priority Critical patent/IT1303736B1/it
Priority to EP99968785A priority patent/EP1131352A2/en
Priority to AU26604/00A priority patent/AU2660400A/en
Priority to PCT/EP1999/008651 priority patent/WO2000027880A2/en
Priority to US09/831,500 priority patent/US6709649B1/en
Priority to JP2000581057A priority patent/JP2003500334A/ja
Priority to CA002348308A priority patent/CA2348308A1/en
Publication of ITMI982441A1 publication Critical patent/ITMI982441A1/it
Application granted granted Critical
Publication of IT1303736B1 publication Critical patent/IT1303736B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IT1998MI002441A 1998-11-11 1998-11-11 Peptidi derivati da rantes con attivita' anti-hiv. IT1303736B1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT1998MI002441A IT1303736B1 (it) 1998-11-11 1998-11-11 Peptidi derivati da rantes con attivita' anti-hiv.
EP99968785A EP1131352A2 (en) 1998-11-11 1999-11-11 Rantes-derived peptides with anti-hiv activity
AU26604/00A AU2660400A (en) 1998-11-11 1999-11-11 Rantes-derived peptides with anti-hiv activity
PCT/EP1999/008651 WO2000027880A2 (en) 1998-11-11 1999-11-11 Rantes-derived peptides with anti-hiv activity
US09/831,500 US6709649B1 (en) 1998-11-11 1999-11-11 RANTES derived peptides with anti-HIV activity
JP2000581057A JP2003500334A (ja) 1998-11-11 1999-11-11 抗ｈｉｖ作用を有するｒａｎｔｅｓ由来ペプチド
CA002348308A CA2348308A1 (en) 1998-11-11 1999-11-11 Rantes-derived peptides with anti-hiv activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI002441A IT1303736B1 (it) 1998-11-11 1998-11-11 Peptidi derivati da rantes con attivita' anti-hiv.

Publications (2)

Publication Number Publication Date
ITMI982441A1 ITMI982441A1 (it) 2000-05-11
IT1303736B1 true IT1303736B1 (it) 2001-02-23

Family

ID=11381034

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998MI002441A IT1303736B1 (it) 1998-11-11 1998-11-11 Peptidi derivati da rantes con attivita' anti-hiv.

Country Status (7)

Country Link
US (1) US6709649B1 (it)
EP (1) EP1131352A2 (it)
JP (1) JP2003500334A (it)
AU (1) AU2660400A (it)
CA (1) CA2348308A1 (it)
IT (1) IT1303736B1 (it)
WO (1) WO2000027880A2 (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20030107A1 (it) * 2003-01-24 2004-07-25 Primm Srl Peptidi derivati da rantes.
CA2552222A1 (en) * 2003-12-30 2005-07-21 Wyeth Antiviral compositions which inhibit paramyxovirus infection
CA2576030A1 (en) * 2004-08-09 2006-02-23 Alios Biopharma Inc. Synthetic hyperglycosylated, protease-resistant polypeptide variants, oral formulations and methods of using the same
US7597884B2 (en) * 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
DE102005049637A1 (de) * 2005-10-14 2007-04-26 Rheinisch-Westfälische Technische Hochschule Aachen Antagonisten gegen die Interaktion von PF4 und RANTES
US20080260820A1 (en) * 2007-04-19 2008-10-23 Gilles Borrelly Oral dosage formulations of protease-resistant polypeptides
US8012474B2 (en) 2007-08-02 2011-09-06 Nov Immune S.A. Anti-RANTES antibodies
JP2012505160A (ja) * 2008-10-06 2012-03-01 カロラス セラピューティクス， インク． 炎症を処置する方法
PT3114139T (pt) 2014-03-04 2022-09-13 Chemomab Ltd Anticorpos anti-eotaxina-2 que reconhecem quimiocinas adicionais de ligação a ccr3

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI972433A0 (fi) * 1994-12-08 1997-06-06 Glaxo Group Ltd Rantes-peptidi ja fragmentteja sekä tätä sisältäviä tulehduksen hoitoon soveltuvia koostumuksia
ATE262346T1 (de) 1995-11-30 2004-04-15 Us Gov Health & Human Serv C-c chemokine die die infektion mit retoviren verhindern
EP0972043A1 (en) * 1996-09-25 2000-01-19 British Biotech Pharmaceuticals Limited Human rantes mutants incapable of aggregate formation
IT1291353B1 (it) 1997-05-12 1999-01-07 San Raffaele Centro Fond Peptidi con attivita' antivirale
US6168784B1 (en) * 1997-09-03 2001-01-02 Gryphon Sciences N-terminal modifications of RANTES and methods of use

Also Published As

Publication number Publication date
WO2000027880A2 (en) 2000-05-18
CA2348308A1 (en) 2000-05-18
AU2660400A (en) 2000-05-29
WO2000027880A3 (en) 2000-10-05
JP2003500334A (ja) 2003-01-07
EP1131352A2 (en) 2001-09-12
US6709649B1 (en) 2004-03-23
ITMI982441A1 (it) 2000-05-11

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