IT1396607B1 - Preparazioni oftalmiche a base di bdnf (brain-derived neurotrophic factor) e loro uso. - Google Patents

Preparazioni oftalmiche a base di bdnf (brain-derived neurotrophic factor) e loro uso.

Info

Publication number
IT1396607B1
IT1396607B1 ITMI2009A002012A ITMI20092012A IT1396607B1 IT 1396607 B1 IT1396607 B1 IT 1396607B1 IT MI2009A002012 A ITMI2009A002012 A IT MI2009A002012A IT MI20092012 A ITMI20092012 A IT MI20092012A IT 1396607 B1 IT1396607 B1 IT 1396607B1
Authority
IT
Italy
Prior art keywords
bdnf
brain
neurotrophic factor
derived neurotrophic
ophthalmic preparations
Prior art date
Application number
ITMI2009A002012A
Other languages
English (en)
Inventor
Luca Giovannini
Marco Sanso'
Luciano Domenici
Original Assignee
Hmfra Hungary Ltd Liability Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42211955&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1396607(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hmfra Hungary Ltd Liability Company filed Critical Hmfra Hungary Ltd Liability Company
Priority to ITMI2009A002012A priority Critical patent/IT1396607B1/it
Priority to PL10809037T priority patent/PL2501362T3/pl
Priority to CN2010800516551A priority patent/CN102639111A/zh
Priority to RS20140644A priority patent/RS53687B1/sr
Priority to CN201610053193.6A priority patent/CN105769750A/zh
Priority to KR1020127012512A priority patent/KR101831793B1/ko
Priority to RU2012120096/15A priority patent/RU2564920C2/ru
Priority to PT108090374T priority patent/PT2501362E/pt
Priority to BR112012011542A priority patent/BR112012011542A2/pt
Priority to CA2781008A priority patent/CA2781008C/en
Priority to PCT/IB2010/003220 priority patent/WO2011058449A2/en
Priority to ES10809037.4T priority patent/ES2524976T3/es
Priority to DK10809037.4T priority patent/DK2501362T3/en
Priority to MX2012005624A priority patent/MX341502B/es
Priority to EP10809037.4A priority patent/EP2501362B1/en
Priority to JP2012538434A priority patent/JP2013510844A/ja
Priority to US13/509,824 priority patent/US9387164B2/en
Priority to SI201030793T priority patent/SI2501362T1/sl
Priority to HRP20141129AT priority patent/HRP20141129T1/hr
Publication of ITMI20092012A1 publication Critical patent/ITMI20092012A1/it
Priority to CL2012001267A priority patent/CL2012001267A1/es
Publication of IT1396607B1 publication Critical patent/IT1396607B1/it
Application granted granted Critical
Priority to CY20141101003T priority patent/CY1115853T1/el
Priority to JP2015219649A priority patent/JP2016026229A/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
ITMI2009A002012A 2009-11-16 2009-11-16 Preparazioni oftalmiche a base di bdnf (brain-derived neurotrophic factor) e loro uso. IT1396607B1 (it)

Priority Applications (22)

Application Number Priority Date Filing Date Title
ITMI2009A002012A IT1396607B1 (it) 2009-11-16 2009-11-16 Preparazioni oftalmiche a base di bdnf (brain-derived neurotrophic factor) e loro uso.
PCT/IB2010/003220 WO2011058449A2 (en) 2009-11-16 2010-11-12 Ophthalmic preparations based on bdnf (brain-derived neurotrophic factor) and their use
DK10809037.4T DK2501362T3 (en) 2009-11-16 2010-11-12 Ophthalmic compositions are based on BDNF (Brain-Derived Neurotrophic Factor), and use thereof
RS20140644A RS53687B1 (sr) 2009-11-16 2010-11-12 Oftamološki preparati na bazi bdnf ("brain-derived neurotrophic factor") i njihova upotreba
CN201610053193.6A CN105769750A (zh) 2009-11-16 2010-11-12 基于bdnf(脑源性神经营养因子)的眼制剂及其用途
KR1020127012512A KR101831793B1 (ko) 2009-11-16 2010-11-12 Ｂｄｎｆ （뇌-유래 신경영양성 인자）에 기반한 안과용 조성물 및 그의 용도
RU2012120096/15A RU2564920C2 (ru) 2009-11-16 2010-11-12 Офтальмологические препараты на основе bdnf (нейротрофического фактора головного мозга) и их применение
PT108090374T PT2501362E (pt) 2009-11-16 2010-11-12 Preparações oftálmicas à base de bdnf (fator neurotrófico derivado do cérebro) e sua utilização
BR112012011542A BR112012011542A2 (pt) 2009-11-16 2010-11-12 preparações oftálmicas com base em bdnf (fator neurotrófico derivado do cérebro) e seu uso
CA2781008A CA2781008C (en) 2009-11-16 2010-11-12 Ophthalmic preparations based on bdnf (brain-derived neurotrophic factor) and their use
PL10809037T PL2501362T3 (pl) 2009-11-16 2010-11-12 Preparaty oczne oparte na BDNF (neurotroficzny czynnik pochodzenia mózgowego) i ich zastosowanie
ES10809037.4T ES2524976T3 (es) 2009-11-16 2010-11-12 Preparaciones oftálmicas basadas en el BDNF (Factor Neurotrófico Derivado del Cerebro) y sus usos
CN2010800516551A CN102639111A (zh) 2009-11-16 2010-11-12 基于bdnf(脑源性神经营养因子)的眼制剂及其用途
MX2012005624A MX341502B (es) 2009-11-16 2010-11-12 Preparaciones oftálmicas basadas en el factor neurotrófico derivado del cerebro y su uso.
EP10809037.4A EP2501362B1 (en) 2009-11-16 2010-11-12 Ophthalmic preparations based on bdnf (brain-derived neurotrophic factor) and their use
JP2012538434A JP2013510844A (ja) 2009-11-16 2010-11-12 Ｂｄｎｆ（脳由来神経栄養因子）をベースとする眼科用製剤およびそれらの使用
US13/509,824 US9387164B2 (en) 2009-11-16 2010-11-12 Methods of treating chronic simple glaucoma with ophthalmic preparations based on BDNF (brain-derived neurotrophic factor)
SI201030793T SI2501362T1 (sl) 2009-11-16 2010-11-12 Oftalmiäśni pripravki na osnovi bdnf (moĺ˝ganskega nevrotrofiäśnega faktorja) in njihova uporaba
HRP20141129AT HRP20141129T1 (hr) 2009-11-16 2010-11-12 Oftalmološki pripravci zasnovani na bdnf (neurotropiäśki faktor porijeklom iz mozga) i njihova primjena
CL2012001267A CL2012001267A1 (es) 2009-11-16 2012-05-15 Preparación oftálmica que comprende un factor neurotrófico derivado del cerebro (bdnf) en una concentración de al menos 15 µg/µl, útil para la prevención y/o tratamiento de enfermedades neurodegenerativas de la retina, nervio óptico y cuerpo genicular lateral.
CY20141101003T CY1115853T1 (el) 2009-11-16 2014-12-02 Οφθαλμικα σκευασματα επι τη βασει bdnf (εγκεφαλικου νευροτροφικου παραγοντα) και η χρηση αυτων
JP2015219649A JP2016026229A (ja) 2009-11-16 2015-11-09 Ｂｄｎｆ（脳由来神経栄養因子）をベースとする眼科用製剤およびそれらの使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI2009A002012A IT1396607B1 (it) 2009-11-16 2009-11-16 Preparazioni oftalmiche a base di bdnf (brain-derived neurotrophic factor) e loro uso.

Publications (2)

Publication Number Publication Date
ITMI20092012A1 ITMI20092012A1 (it) 2011-05-17
IT1396607B1 true IT1396607B1 (it) 2012-12-14

Family

ID=42211955

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI2009A002012A IT1396607B1 (it) 2009-11-16 2009-11-16 Preparazioni oftalmiche a base di bdnf (brain-derived neurotrophic factor) e loro uso.

Country Status (20)

Country Link
US (1) US9387164B2 (it)
EP (1) EP2501362B1 (it)
JP (2) JP2013510844A (it)
KR (1) KR101831793B1 (it)
CN (2) CN105769750A (it)
BR (1) BR112012011542A2 (it)
CA (1) CA2781008C (it)
CL (1) CL2012001267A1 (it)
CY (1) CY1115853T1 (it)
DK (1) DK2501362T3 (it)
ES (1) ES2524976T3 (it)
HR (1) HRP20141129T1 (it)
IT (1) IT1396607B1 (it)
MX (1) MX341502B (it)
PL (1) PL2501362T3 (it)
PT (1) PT2501362E (it)
RS (1) RS53687B1 (it)
RU (1) RU2564920C2 (it)
SI (1) SI2501362T1 (it)
WO (1) WO2011058449A2 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12130900B2 (en) 2014-08-28 2024-10-29 Facetec, Inc. Method and apparatus to dynamically control facial illumination
SG10201913468YA (en) * 2015-07-13 2020-03-30 Tohoku Techno Arch Co Ltd Composition for optic nerve protection
ITUA20162343A1 (it) * 2016-04-06 2017-10-06 Luciano Domenici Formulazioni intranasali di bdnf per uso nel trattamento di malattie neurodegenerative
CN111317814B (zh) * 2020-04-23 2020-12-18 中国中医科学院眼科医院 一种冰片联合神经营养因子组合物及应用
EP4616865A1 (en) * 2024-03-13 2025-09-17 Dompe' Farmaceutici SpA Bdnf for the treatment of rhodopsin-mediated retinitis pigmentosa

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283911B1 (it) * 1996-02-05 1998-05-07 Farmigea Spa Soluzioni oftalmiche viscosizzate con polisaccaridi della gomma di tamarindo
JPH10212241A (ja) 1996-05-27 1998-08-11 Sumitomo Pharmaceut Co Ltd Ｂｄｎｆを安定に含有する製剤
KR100514277B1 (ko) * 1996-09-13 2005-09-13 유겐가이샤 사이센딴이가꾸겡꾸쇼 신경 영양 인자의 안과용 조성물, 시신경 기능 장애 치료제 및 시신경 기능 장애 치료 방법
IT1305294B1 (it) 1999-01-29 2001-05-04 Alessandro Lambiase Uso del nerve growth factor nella terapia di patologie a carico deitessuti intraoculari.
JP2003048851A (ja) * 2001-08-03 2003-02-21 Nidek Co Ltd 視細胞障害疾患治療薬
WO2006046584A1 (ja) 2004-10-26 2006-05-04 Santen Pharmaceutical Co., Ltd. 視細胞障害治療剤
US20070014760A1 (en) * 2005-07-18 2007-01-18 Peyman Gholam A Enhanced recovery following ocular surgery
US7625927B2 (en) * 2006-02-27 2009-12-01 Alcon Research, Ltd. Method of treating glaucoma
ITRM20070510A1 (it) * 2007-10-02 2009-04-03 Rmfa Trading S A Composizioni oftalmiche a base di polisaccaride del seme di tamarindo e acido ialuronico.

Also Published As

Publication number Publication date
KR20120101390A (ko) 2012-09-13
KR101831793B1 (ko) 2018-02-23
JP2016026229A (ja) 2016-02-12
SI2501362T1 (sl) 2014-12-31
RS53687B1 (sr) 2015-04-30
CN102639111A (zh) 2012-08-15
ES2524976T3 (es) 2014-12-16
EP2501362B1 (en) 2014-10-08
CL2012001267A1 (es) 2012-12-07
DK2501362T3 (en) 2014-11-17
RU2012120096A (ru) 2013-11-20
JP2013510844A (ja) 2013-03-28
PT2501362E (pt) 2014-12-04
MX341502B (es) 2016-08-22
MX2012005624A (es) 2012-09-28
ITMI20092012A1 (it) 2011-05-17
WO2011058449A2 (en) 2011-05-19
BR112012011542A2 (pt) 2016-06-28
PL2501362T3 (pl) 2015-02-27
CA2781008C (en) 2018-02-06
EP2501362A2 (en) 2012-09-26
US9387164B2 (en) 2016-07-12
CY1115853T1 (el) 2017-01-25
HRP20141129T1 (hr) 2015-01-02
US20120258916A1 (en) 2012-10-11
RU2564920C2 (ru) 2015-10-10
CA2781008A1 (en) 2011-05-19
CN105769750A (zh) 2016-07-20
WO2011058449A3 (en) 2011-12-01

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