IT1400620B1 - Cementi ossei compositi iniettabili, osteoinduttivi ed a rilascio di farmaci - Google Patents

Cementi ossei compositi iniettabili, osteoinduttivi ed a rilascio di farmaci

Info

Publication number
IT1400620B1
IT1400620B1 ITTO2010A000401A ITTO20100401A IT1400620B1 IT 1400620 B1 IT1400620 B1 IT 1400620B1 IT TO2010A000401 A ITTO2010A000401 A IT TO2010A000401A IT TO20100401 A ITTO20100401 A IT TO20100401A IT 1400620 B1 IT1400620 B1 IT 1400620B1
Authority
IT
Italy
Prior art keywords
cements
osteoinductive
injectable
bone
drug release
Prior art date
Application number
ITTO2010A000401A
Other languages
English (en)
Inventor
Sara Ferraris
Enrica Verne
Mauro Bergui
Barbara Onida
Marta Miola
Brovarone Chiara Vitale
Francesco Baino
Francesca Tallia
Original Assignee
Torino Politecnico
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torino Politecnico filed Critical Torino Politecnico
Priority to ITTO2010A000401A priority Critical patent/IT1400620B1/it
Priority to US13/697,076 priority patent/US20130059013A1/en
Priority to EP11728668.2A priority patent/EP2569025B1/en
Priority to PCT/IB2011/052094 priority patent/WO2011141889A1/en
Publication of ITTO20100401A1 publication Critical patent/ITTO20100401A1/it
Application granted granted Critical
Publication of IT1400620B1 publication Critical patent/IT1400620B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0052—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with an inorganic matrix
    • A61L24/0068—Inorganic materials not covered by groups A61L24/0057 or A61L24/0063
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0052—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with an inorganic matrix
    • A61L24/0063—Phosphorus containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/427—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of other specific inorganic materials not covered by A61L27/422 or A61L27/425
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/44—Radioisotopes, radionuclides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Composite Materials (AREA)
  • Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ITTO2010A000401A 2010-05-13 2010-05-13 Cementi ossei compositi iniettabili, osteoinduttivi ed a rilascio di farmaci IT1400620B1 (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ITTO2010A000401A IT1400620B1 (it) 2010-05-13 2010-05-13 Cementi ossei compositi iniettabili, osteoinduttivi ed a rilascio di farmaci
US13/697,076 US20130059013A1 (en) 2010-05-13 2011-05-12 Injectable osteoinductive bone cements
EP11728668.2A EP2569025B1 (en) 2010-05-13 2011-05-12 Injectable osteoinductive bone cements
PCT/IB2011/052094 WO2011141889A1 (en) 2010-05-13 2011-05-12 Injectable osteoinductive bone cements

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITTO2010A000401A IT1400620B1 (it) 2010-05-13 2010-05-13 Cementi ossei compositi iniettabili, osteoinduttivi ed a rilascio di farmaci

Publications (2)

Publication Number Publication Date
ITTO20100401A1 ITTO20100401A1 (it) 2011-11-14
IT1400620B1 true IT1400620B1 (it) 2013-06-14

Family

ID=43242768

Family Applications (1)

Application Number Title Priority Date Filing Date
ITTO2010A000401A IT1400620B1 (it) 2010-05-13 2010-05-13 Cementi ossei compositi iniettabili, osteoinduttivi ed a rilascio di farmaci

Country Status (4)

Country Link
US (1) US20130059013A1 (it)
EP (1) EP2569025B1 (it)
IT (1) IT1400620B1 (it)
WO (1) WO2011141889A1 (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012014418A1 (de) 2012-07-20 2014-01-23 Heraeus Medical Gmbh Pastenförmiger Knochenzement
DE102012108320A1 (de) * 2012-09-07 2014-03-13 Aap Biomaterials Gmbh Knochenzement sowie unter Verwendung eines Knochenzements hergestellter Formkörper
DE102012022134A1 (de) * 2012-11-13 2014-05-15 Heraeus Medical Gmbh Polymethylmethacrylat-Knochenzement
US20140277505A1 (en) * 2013-03-15 2014-09-18 Dale Mitchell Spinal implants with bioactive glass markers
TWI651103B (zh) 2013-12-13 2019-02-21 萊特醫技股份有限公司 多相骨移植替代材料
US10239022B2 (en) * 2016-06-02 2019-03-26 C-Crete Technologies, Llc Porous calcium-silicates and method of synthesis
CN106075565B (zh) * 2016-07-05 2019-02-15 盐城倍尔生生物科技有限公司 自固化可降解的生物活性膏剂骨修复材料及应用
CN109939261B (zh) * 2019-04-24 2021-06-11 东南大学 一种可调控磷酸钙骨水泥注射性的固化液及其制备方法和应用
CN114681666B (zh) * 2022-02-16 2022-12-30 中南大学湘雅三医院 具备光热抗肿瘤和抗菌作用的骨修复材料及其制备方法
CN115969809B (zh) * 2022-12-30 2025-07-04 广西璟炜生物技术有限公司 一种复合蛋白包裹的功能微球的制备方法及其在鼻腔黏膜修复的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4753530B2 (ja) * 2001-05-25 2011-08-24 インペリアル イノヴェーションズ リミテッド 発泡ゾル−ゲル及びその製造方法
US20040224864A1 (en) * 2003-02-26 2004-11-11 Patterson William R. Sterilized embolic compositions
DE102005001078A1 (de) * 2005-01-08 2006-07-20 Schott Ag Glaspulver, insbesondere biologisch aktives Glaspulver und Verfahren zur Herstellung von Glaspulver, insbesondere biologisch aktivem Glaspulver
US8916198B2 (en) * 2006-04-25 2014-12-23 Washington State University Mesoporous calcium silicate compositions and methods for synthesis of mesoporous calcium silicate for controlled release of bioactive agents
WO2010023179A2 (fr) * 2008-08-27 2010-03-04 Rauis Andre Substitut osseux à base de bioverre poreux et de sulfate de calcium

Also Published As

Publication number Publication date
WO2011141889A1 (en) 2011-11-17
ITTO20100401A1 (it) 2011-11-14
US20130059013A1 (en) 2013-03-07
EP2569025B1 (en) 2015-07-29
EP2569025A1 (en) 2013-03-20

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