IT1401142B1 - Procedimento per la preparazione di compresse a rilascio controllato comprendenti melatonina - Google Patents
Procedimento per la preparazione di compresse a rilascio controllato comprendenti melatoninaInfo
- Publication number
- IT1401142B1 IT1401142B1 ITMI2010A001374A ITMI20101374A IT1401142B1 IT 1401142 B1 IT1401142 B1 IT 1401142B1 IT MI2010A001374 A ITMI2010A001374 A IT MI2010A001374A IT MI20101374 A ITMI20101374 A IT MI20101374A IT 1401142 B1 IT1401142 B1 IT 1401142B1
- Authority
- IT
- Italy
- Prior art keywords
- procedure
- preparation
- tablets including
- including melatonin
- controlled tablets
- Prior art date
Links
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 title 1
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 title 1
- 229960003987 melatonin Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/005—Coating of tablets or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2010A001374A IT1401142B1 (it) | 2010-07-26 | 2010-07-26 | Procedimento per la preparazione di compresse a rilascio controllato comprendenti melatonina |
| PCT/EP2011/062634 WO2012013595A1 (en) | 2010-07-26 | 2011-07-22 | Three-phase controlled-release tablet comprising melatonin and process of preparation |
| ES11748604.3T ES2674170T3 (es) | 2010-07-26 | 2011-07-22 | Comprimido de liberación controlada en tres fases que comprende melatonina y proceso de preparación |
| US13/810,061 US20130122092A1 (en) | 2010-07-26 | 2011-07-22 | Three-phase controlled-release tablet comprising melatonin and process of preparation |
| EP11748604.3A EP2598124B1 (en) | 2010-07-26 | 2011-07-22 | Three-phase controlled-release tablet comprising melatonin and process of preparation |
| EA201300175A EA201300175A1 (ru) | 2010-07-26 | 2011-07-22 | Таблетка с контролируемым трехфазным высвобождением, содержащая мелатонин, и способ ее изготовления |
| US15/443,122 US20170165232A1 (en) | 2010-07-26 | 2017-02-27 | Three-phase controlled-release tablet comprising melatonin and process of preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2010A001374A IT1401142B1 (it) | 2010-07-26 | 2010-07-26 | Procedimento per la preparazione di compresse a rilascio controllato comprendenti melatonina |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITMI20101374A1 ITMI20101374A1 (it) | 2012-01-27 |
| IT1401142B1 true IT1401142B1 (it) | 2013-07-12 |
Family
ID=43513713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI2010A001374A IT1401142B1 (it) | 2010-07-26 | 2010-07-26 | Procedimento per la preparazione di compresse a rilascio controllato comprendenti melatonina |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20130122092A1 (it) |
| EP (1) | EP2598124B1 (it) |
| EA (1) | EA201300175A1 (it) |
| ES (1) | ES2674170T3 (it) |
| IT (1) | IT1401142B1 (it) |
| WO (1) | WO2012013595A1 (it) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2761212A1 (en) * | 2011-12-07 | 2013-06-07 | Pharmascience Inc. | Disintegrant-free delayed release doxylamine and pyridoxine formulation and process of it manufacturing |
| MY177906A (en) * | 2014-02-06 | 2020-09-25 | Sequential Medicine Ltd | Composition and method for aiding sleep |
| DK2949322T3 (en) * | 2014-05-28 | 2018-07-23 | Valpharma S P A | FORMULATION FOR ORAL ADMINISTRATION COMPREHENSIVE MELATONIN IN STABLE FORM AND PROCEDURE FOR PREPARING THEREOF |
| NL2015272B1 (en) * | 2015-08-05 | 2017-05-02 | Versailles B V | Melatonin formulations and methods for preparation and use. |
| WO2019038586A1 (en) | 2017-08-19 | 2019-02-28 | Ftf Pharma Private Limited | PHARMACEUTICAL COMPOSITION OF MELATONIN |
| GB2617102A (en) * | 2022-03-29 | 2023-10-04 | John Hemming Trading Ltd | Sleep therapy |
| CN116172979B (zh) * | 2023-02-15 | 2024-10-15 | 浙江贝灵生物医药有限公司 | 一种褪黑素缓释小丸及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6723342B1 (en) * | 1999-02-08 | 2004-04-20 | Fmc Corporation | Edible coating composition |
| IT1318524B1 (it) * | 2000-05-17 | 2003-08-27 | Ambros Pharma S R L | Composizioni a rilascio controllato contenenti un principio attivo,preferibilmente melatonina, e processo di preparazione delle stesse. |
| KR20070087678A (ko) * | 2004-12-20 | 2007-08-28 | 컬리지움 파마슈티칼, 인코포레이티드 | 수면 장애용 약제 조성물 |
| US20080171085A1 (en) * | 2007-01-11 | 2008-07-17 | Natrol, Inc. | Novel biphasic delivery system for a pharmaceutical or nutraceutical composition and method of administration |
| US20080254121A1 (en) * | 2007-04-10 | 2008-10-16 | Iomedix Sleep International Srl | Multi-layer melatonin composition |
| US20100159001A1 (en) * | 2008-12-19 | 2010-06-24 | Cardinal John R | Extended-Release Pharmaceutical Formulations |
-
2010
- 2010-07-26 IT ITMI2010A001374A patent/IT1401142B1/it active
-
2011
- 2011-07-22 WO PCT/EP2011/062634 patent/WO2012013595A1/en not_active Ceased
- 2011-07-22 US US13/810,061 patent/US20130122092A1/en not_active Abandoned
- 2011-07-22 EA EA201300175A patent/EA201300175A1/ru unknown
- 2011-07-22 EP EP11748604.3A patent/EP2598124B1/en active Active
- 2011-07-22 ES ES11748604.3T patent/ES2674170T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012013595A1 (en) | 2012-02-02 |
| US20130122092A1 (en) | 2013-05-16 |
| ITMI20101374A1 (it) | 2012-01-27 |
| EP2598124B1 (en) | 2018-04-04 |
| EA201300175A1 (ru) | 2013-05-30 |
| ES2674170T3 (es) | 2018-06-27 |
| EP2598124A1 (en) | 2013-06-05 |
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