IT1401142B1 - Procedimento per la preparazione di compresse a rilascio controllato comprendenti melatonina - Google Patents

Procedimento per la preparazione di compresse a rilascio controllato comprendenti melatonina

Info

Publication number
IT1401142B1
IT1401142B1 ITMI2010A001374A ITMI20101374A IT1401142B1 IT 1401142 B1 IT1401142 B1 IT 1401142B1 IT MI2010A001374 A ITMI2010A001374 A IT MI2010A001374A IT MI20101374 A ITMI20101374 A IT MI20101374A IT 1401142 B1 IT1401142 B1 IT 1401142B1
Authority
IT
Italy
Prior art keywords
procedure
preparation
tablets including
including melatonin
controlled tablets
Prior art date
Application number
ITMI2010A001374A
Other languages
English (en)
Inventor
Bojidar Mihaylov Stankov
Original Assignee
Ambros Pharma S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambros Pharma S R L filed Critical Ambros Pharma S R L
Priority to ITMI2010A001374A priority Critical patent/IT1401142B1/it
Priority to PCT/EP2011/062634 priority patent/WO2012013595A1/en
Priority to ES11748604.3T priority patent/ES2674170T3/es
Priority to US13/810,061 priority patent/US20130122092A1/en
Priority to EP11748604.3A priority patent/EP2598124B1/en
Priority to EA201300175A priority patent/EA201300175A1/ru
Publication of ITMI20101374A1 publication Critical patent/ITMI20101374A1/it
Application granted granted Critical
Publication of IT1401142B1 publication Critical patent/IT1401142B1/it
Priority to US15/443,122 priority patent/US20170165232A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/005Coating of tablets or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ITMI2010A001374A 2010-07-26 2010-07-26 Procedimento per la preparazione di compresse a rilascio controllato comprendenti melatonina IT1401142B1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITMI2010A001374A IT1401142B1 (it) 2010-07-26 2010-07-26 Procedimento per la preparazione di compresse a rilascio controllato comprendenti melatonina
PCT/EP2011/062634 WO2012013595A1 (en) 2010-07-26 2011-07-22 Three-phase controlled-release tablet comprising melatonin and process of preparation
ES11748604.3T ES2674170T3 (es) 2010-07-26 2011-07-22 Comprimido de liberación controlada en tres fases que comprende melatonina y proceso de preparación
US13/810,061 US20130122092A1 (en) 2010-07-26 2011-07-22 Three-phase controlled-release tablet comprising melatonin and process of preparation
EP11748604.3A EP2598124B1 (en) 2010-07-26 2011-07-22 Three-phase controlled-release tablet comprising melatonin and process of preparation
EA201300175A EA201300175A1 (ru) 2010-07-26 2011-07-22 Таблетка с контролируемым трехфазным высвобождением, содержащая мелатонин, и способ ее изготовления
US15/443,122 US20170165232A1 (en) 2010-07-26 2017-02-27 Three-phase controlled-release tablet comprising melatonin and process of preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI2010A001374A IT1401142B1 (it) 2010-07-26 2010-07-26 Procedimento per la preparazione di compresse a rilascio controllato comprendenti melatonina

Publications (2)

Publication Number Publication Date
ITMI20101374A1 ITMI20101374A1 (it) 2012-01-27
IT1401142B1 true IT1401142B1 (it) 2013-07-12

Family

ID=43513713

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI2010A001374A IT1401142B1 (it) 2010-07-26 2010-07-26 Procedimento per la preparazione di compresse a rilascio controllato comprendenti melatonina

Country Status (6)

Country Link
US (1) US20130122092A1 (it)
EP (1) EP2598124B1 (it)
EA (1) EA201300175A1 (it)
ES (1) ES2674170T3 (it)
IT (1) IT1401142B1 (it)
WO (1) WO2012013595A1 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2761212A1 (en) * 2011-12-07 2013-06-07 Pharmascience Inc. Disintegrant-free delayed release doxylamine and pyridoxine formulation and process of it manufacturing
MY177906A (en) * 2014-02-06 2020-09-25 Sequential Medicine Ltd Composition and method for aiding sleep
DK2949322T3 (en) * 2014-05-28 2018-07-23 Valpharma S P A FORMULATION FOR ORAL ADMINISTRATION COMPREHENSIVE MELATONIN IN STABLE FORM AND PROCEDURE FOR PREPARING THEREOF
NL2015272B1 (en) * 2015-08-05 2017-05-02 Versailles B V Melatonin formulations and methods for preparation and use.
WO2019038586A1 (en) 2017-08-19 2019-02-28 Ftf Pharma Private Limited PHARMACEUTICAL COMPOSITION OF MELATONIN
GB2617102A (en) * 2022-03-29 2023-10-04 John Hemming Trading Ltd Sleep therapy
CN116172979B (zh) * 2023-02-15 2024-10-15 浙江贝灵生物医药有限公司 一种褪黑素缓释小丸及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6723342B1 (en) * 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
IT1318524B1 (it) * 2000-05-17 2003-08-27 Ambros Pharma S R L Composizioni a rilascio controllato contenenti un principio attivo,preferibilmente melatonina, e processo di preparazione delle stesse.
KR20070087678A (ko) * 2004-12-20 2007-08-28 컬리지움 파마슈티칼, 인코포레이티드 수면 장애용 약제 조성물
US20080171085A1 (en) * 2007-01-11 2008-07-17 Natrol, Inc. Novel biphasic delivery system for a pharmaceutical or nutraceutical composition and method of administration
US20080254121A1 (en) * 2007-04-10 2008-10-16 Iomedix Sleep International Srl Multi-layer melatonin composition
US20100159001A1 (en) * 2008-12-19 2010-06-24 Cardinal John R Extended-Release Pharmaceutical Formulations

Also Published As

Publication number Publication date
WO2012013595A1 (en) 2012-02-02
US20130122092A1 (en) 2013-05-16
ITMI20101374A1 (it) 2012-01-27
EP2598124B1 (en) 2018-04-04
EA201300175A1 (ru) 2013-05-30
ES2674170T3 (es) 2018-06-27
EP2598124A1 (en) 2013-06-05

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