IT201700105483A1 - Metodo per la diagnosi e la prognosi di patologie neurodegenerative e neuroinfiammatorie - Google Patents
Metodo per la diagnosi e la prognosi di patologie neurodegenerative e neuroinfiammatorieInfo
- Publication number
- IT201700105483A1 IT201700105483A1 IT102017000105483A IT201700105483A IT201700105483A1 IT 201700105483 A1 IT201700105483 A1 IT 201700105483A1 IT 102017000105483 A IT102017000105483 A IT 102017000105483A IT 201700105483 A IT201700105483 A IT 201700105483A IT 201700105483 A1 IT201700105483 A1 IT 201700105483A1
- Authority
- IT
- Italy
- Prior art keywords
- prognosis
- neurodegenerative
- diagnosis
- neuroinflammatory diseases
- neuroinflammatory
- Prior art date
Links
- 208000036110 Neuroinflammatory disease Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
- 230000000626 neurodegenerative effect Effects 0.000 title 1
- 238000004393 prognosis Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102017000105483A IT201700105483A1 (it) | 2017-09-21 | 2017-09-21 | Metodo per la diagnosi e la prognosi di patologie neurodegenerative e neuroinfiammatorie |
| US16/649,247 US11359243B2 (en) | 2017-09-21 | 2018-09-20 | Method for the diagnosis and prognosis of neurodegenerative and neuroinflammatory pathologies |
| EP18789217.9A EP3685167B1 (en) | 2017-09-21 | 2018-09-20 | Method for the diagnosis and prognosis of neurodegenerative and neuroinflammatory diseases |
| CN201880069312.4A CN111279196B (zh) | 2017-09-21 | 2018-09-20 | 用于神经变性疾病和神经炎性疾病的诊断和预后的方法 |
| CA3076316A CA3076316A1 (en) | 2017-09-21 | 2018-09-20 | Method for the diagnosis and prognosis of neurodegenerative and neuroinflammatory diseases |
| ES18789217T ES2905144T3 (es) | 2017-09-21 | 2018-09-20 | Método para el diagnóstico y el pronóstico de enfermedades neurodegenerativas y neuroinflamatorias |
| PL18789217T PL3685167T3 (pl) | 2017-09-21 | 2018-09-20 | Sposób diagnozy i prognozy chorób neurodegeneracyjnych i neurozapalnych |
| PCT/IB2018/057261 WO2019058303A1 (en) | 2017-09-21 | 2018-09-20 | DIAGNOSTIC AND PROGNOSTIC METHODS FOR NEURODEGENERATIVE AND NEUROINFLAMMATORY DISEASES |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102017000105483A IT201700105483A1 (it) | 2017-09-21 | 2017-09-21 | Metodo per la diagnosi e la prognosi di patologie neurodegenerative e neuroinfiammatorie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT201700105483A1 true IT201700105483A1 (it) | 2019-03-21 |
Family
ID=61024877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT102017000105483A IT201700105483A1 (it) | 2017-09-21 | 2017-09-21 | Metodo per la diagnosi e la prognosi di patologie neurodegenerative e neuroinfiammatorie |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11359243B2 (it) |
| EP (1) | EP3685167B1 (it) |
| CN (1) | CN111279196B (it) |
| CA (1) | CA3076316A1 (it) |
| ES (1) | ES2905144T3 (it) |
| IT (1) | IT201700105483A1 (it) |
| PL (1) | PL3685167T3 (it) |
| WO (1) | WO2019058303A1 (it) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115176163B (zh) * | 2019-11-29 | 2026-03-24 | 富士胶片和光纯药株式会社 | 辅助阿尔茨海默型痴呆症或轻度认知障碍的诊断的方法、生物标志物、试剂盒及装置 |
| CN115920040A (zh) * | 2021-07-08 | 2023-04-07 | 北京干细胞与再生医学研究院 | 用于治疗神经退行性疾病或中枢神经系统损伤的靶点及小分子化合物 |
| WO2023232108A1 (zh) * | 2022-06-02 | 2023-12-07 | 浙江大学医学院附属第一医院 | 诊断及鉴别诊断非阿尔兹海默病认知障碍的方法、系统、组合物和试剂盒 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015061634A2 (en) * | 2013-10-24 | 2015-04-30 | Nanosomix, Inc. | Biomarkers and diagnostic methods for alzheimer's disease and other neurodegenerative disorders |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002012284A2 (en) * | 2000-08-04 | 2002-02-14 | Loma Linda University Medical Center | Iron regulating protein-2 (irp-2) as a diagnostic for neurodegenerative disease |
-
2017
- 2017-09-21 IT IT102017000105483A patent/IT201700105483A1/it unknown
-
2018
- 2018-09-20 ES ES18789217T patent/ES2905144T3/es active Active
- 2018-09-20 EP EP18789217.9A patent/EP3685167B1/en active Active
- 2018-09-20 WO PCT/IB2018/057261 patent/WO2019058303A1/en not_active Ceased
- 2018-09-20 US US16/649,247 patent/US11359243B2/en active Active
- 2018-09-20 CN CN201880069312.4A patent/CN111279196B/zh active Active
- 2018-09-20 CA CA3076316A patent/CA3076316A1/en active Pending
- 2018-09-20 PL PL18789217T patent/PL3685167T3/pl unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015061634A2 (en) * | 2013-10-24 | 2015-04-30 | Nanosomix, Inc. | Biomarkers and diagnostic methods for alzheimer's disease and other neurodegenerative disorders |
Non-Patent Citations (4)
| Title |
|---|
| ALEXANDER G. THOMPSON ET AL: "Extracellular vesicles in neurodegenerative disease - pathogenesis to biomarkers", NATURE REVIEWS. NEUROLOGY, vol. 12, no. 6, 13 May 2016 (2016-05-13), US, pages 346 - 357, XP055454065, ISSN: 1759-4758, DOI: 10.1038/nrneurol.2016.68 * |
| ANNAMARIA NIGRO ET AL: "Myeloid Extracellular Vesicles: Messengers from the Demented Brain", FRONTIERS IN IMMUNOLOGY, vol. 7, 29 January 2016 (2016-01-29), XP055454041, DOI: 10.3389/fimmu.2016.00017 * |
| BOHLEN CHRISTOPHER J ET AL: "Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures", NEURON, CELL PRESS, US, vol. 94, no. 4, 17 May 2017 (2017-05-17), pages 759, XP085026691, ISSN: 0896-6273, DOI: 10.1016/J.NEURON.2017.04.043 * |
| JUN-ICHI SATOH ET AL: "TMEM119 marks a subset of microglia in the human brain : Human microglial marker TMEM119", NEUROPATHOLOGY, vol. 36, no. 1, 1 February 2016 (2016-02-01), JP, pages 39 - 49, XP055453989, ISSN: 0919-6544, DOI: 10.1111/neup.12235 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US11359243B2 (en) | 2022-06-14 |
| EP3685167B1 (en) | 2021-11-10 |
| US20200216902A1 (en) | 2020-07-09 |
| CN111279196A (zh) | 2020-06-12 |
| ES2905144T3 (es) | 2022-04-07 |
| PL3685167T3 (pl) | 2022-03-07 |
| CA3076316A1 (en) | 2019-03-28 |
| EP3685167A1 (en) | 2020-07-29 |
| CN111279196B (zh) | 2023-07-14 |
| WO2019058303A1 (en) | 2019-03-28 |
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