IT201700105483A1 - Metodo per la diagnosi e la prognosi di patologie neurodegenerative e neuroinfiammatorie - Google Patents

Metodo per la diagnosi e la prognosi di patologie neurodegenerative e neuroinfiammatorie

Info

Publication number
IT201700105483A1
IT201700105483A1 IT102017000105483A IT201700105483A IT201700105483A1 IT 201700105483 A1 IT201700105483 A1 IT 201700105483A1 IT 102017000105483 A IT102017000105483 A IT 102017000105483A IT 201700105483 A IT201700105483 A IT 201700105483A IT 201700105483 A1 IT201700105483 A1 IT 201700105483A1
Authority
IT
Italy
Prior art keywords
prognosis
neurodegenerative
diagnosis
neuroinflammatory diseases
neuroinflammatory
Prior art date
Application number
IT102017000105483A
Other languages
English (en)
Inventor
Armando Chierchia
Fabio Bianco
Original Assignee
Braindtech S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Braindtech S R L filed Critical Braindtech S R L
Priority to IT102017000105483A priority Critical patent/IT201700105483A1/it
Priority to US16/649,247 priority patent/US11359243B2/en
Priority to EP18789217.9A priority patent/EP3685167B1/en
Priority to CN201880069312.4A priority patent/CN111279196B/zh
Priority to CA3076316A priority patent/CA3076316A1/en
Priority to ES18789217T priority patent/ES2905144T3/es
Priority to PL18789217T priority patent/PL3685167T3/pl
Priority to PCT/IB2018/057261 priority patent/WO2019058303A1/en
Publication of IT201700105483A1 publication Critical patent/IT201700105483A1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IT102017000105483A 2017-09-21 2017-09-21 Metodo per la diagnosi e la prognosi di patologie neurodegenerative e neuroinfiammatorie IT201700105483A1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT102017000105483A IT201700105483A1 (it) 2017-09-21 2017-09-21 Metodo per la diagnosi e la prognosi di patologie neurodegenerative e neuroinfiammatorie
US16/649,247 US11359243B2 (en) 2017-09-21 2018-09-20 Method for the diagnosis and prognosis of neurodegenerative and neuroinflammatory pathologies
EP18789217.9A EP3685167B1 (en) 2017-09-21 2018-09-20 Method for the diagnosis and prognosis of neurodegenerative and neuroinflammatory diseases
CN201880069312.4A CN111279196B (zh) 2017-09-21 2018-09-20 用于神经变性疾病和神经炎性疾病的诊断和预后的方法
CA3076316A CA3076316A1 (en) 2017-09-21 2018-09-20 Method for the diagnosis and prognosis of neurodegenerative and neuroinflammatory diseases
ES18789217T ES2905144T3 (es) 2017-09-21 2018-09-20 Método para el diagnóstico y el pronóstico de enfermedades neurodegenerativas y neuroinflamatorias
PL18789217T PL3685167T3 (pl) 2017-09-21 2018-09-20 Sposób diagnozy i prognozy chorób neurodegeneracyjnych i neurozapalnych
PCT/IB2018/057261 WO2019058303A1 (en) 2017-09-21 2018-09-20 DIAGNOSTIC AND PROGNOSTIC METHODS FOR NEURODEGENERATIVE AND NEUROINFLAMMATORY DISEASES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102017000105483A IT201700105483A1 (it) 2017-09-21 2017-09-21 Metodo per la diagnosi e la prognosi di patologie neurodegenerative e neuroinfiammatorie

Publications (1)

Publication Number Publication Date
IT201700105483A1 true IT201700105483A1 (it) 2019-03-21

Family

ID=61024877

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102017000105483A IT201700105483A1 (it) 2017-09-21 2017-09-21 Metodo per la diagnosi e la prognosi di patologie neurodegenerative e neuroinfiammatorie

Country Status (8)

Country Link
US (1) US11359243B2 (it)
EP (1) EP3685167B1 (it)
CN (1) CN111279196B (it)
CA (1) CA3076316A1 (it)
ES (1) ES2905144T3 (it)
IT (1) IT201700105483A1 (it)
PL (1) PL3685167T3 (it)
WO (1) WO2019058303A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115176163B (zh) * 2019-11-29 2026-03-24 富士胶片和光纯药株式会社 辅助阿尔茨海默型痴呆症或轻度认知障碍的诊断的方法、生物标志物、试剂盒及装置
CN115920040A (zh) * 2021-07-08 2023-04-07 北京干细胞与再生医学研究院 用于治疗神经退行性疾病或中枢神经系统损伤的靶点及小分子化合物
WO2023232108A1 (zh) * 2022-06-02 2023-12-07 浙江大学医学院附属第一医院 诊断及鉴别诊断非阿尔兹海默病认知障碍的方法、系统、组合物和试剂盒

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015061634A2 (en) * 2013-10-24 2015-04-30 Nanosomix, Inc. Biomarkers and diagnostic methods for alzheimer's disease and other neurodegenerative disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002012284A2 (en) * 2000-08-04 2002-02-14 Loma Linda University Medical Center Iron regulating protein-2 (irp-2) as a diagnostic for neurodegenerative disease

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015061634A2 (en) * 2013-10-24 2015-04-30 Nanosomix, Inc. Biomarkers and diagnostic methods for alzheimer's disease and other neurodegenerative disorders

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ALEXANDER G. THOMPSON ET AL: "Extracellular vesicles in neurodegenerative disease - pathogenesis to biomarkers", NATURE REVIEWS. NEUROLOGY, vol. 12, no. 6, 13 May 2016 (2016-05-13), US, pages 346 - 357, XP055454065, ISSN: 1759-4758, DOI: 10.1038/nrneurol.2016.68 *
ANNAMARIA NIGRO ET AL: "Myeloid Extracellular Vesicles: Messengers from the Demented Brain", FRONTIERS IN IMMUNOLOGY, vol. 7, 29 January 2016 (2016-01-29), XP055454041, DOI: 10.3389/fimmu.2016.00017 *
BOHLEN CHRISTOPHER J ET AL: "Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures", NEURON, CELL PRESS, US, vol. 94, no. 4, 17 May 2017 (2017-05-17), pages 759, XP085026691, ISSN: 0896-6273, DOI: 10.1016/J.NEURON.2017.04.043 *
JUN-ICHI SATOH ET AL: "TMEM119 marks a subset of microglia in the human brain : Human microglial marker TMEM119", NEUROPATHOLOGY, vol. 36, no. 1, 1 February 2016 (2016-02-01), JP, pages 39 - 49, XP055453989, ISSN: 0919-6544, DOI: 10.1111/neup.12235 *

Also Published As

Publication number Publication date
US11359243B2 (en) 2022-06-14
EP3685167B1 (en) 2021-11-10
US20200216902A1 (en) 2020-07-09
CN111279196A (zh) 2020-06-12
ES2905144T3 (es) 2022-04-07
PL3685167T3 (pl) 2022-03-07
CA3076316A1 (en) 2019-03-28
EP3685167A1 (en) 2020-07-29
CN111279196B (zh) 2023-07-14
WO2019058303A1 (en) 2019-03-28

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