IT201900004571A1 - Inibitore di miR-129 e suoi usi - Google Patents

Inibitore di miR-129 e suoi usi

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Publication number
IT201900004571A1
IT201900004571A1 IT102019000004571A IT201900004571A IT201900004571A1 IT 201900004571 A1 IT201900004571 A1 IT 201900004571A1 IT 102019000004571 A IT102019000004571 A IT 102019000004571A IT 201900004571 A IT201900004571 A IT 201900004571A IT 201900004571 A1 IT201900004571 A1 IT 201900004571A1
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IT
Italy
Prior art keywords
mir
inhibitor
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IT102019000004571A
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English (en)
Inventor
Stefania Corti
Monica Nizzardo
Silvia Maria Luisa Barabino
Alessia Loffreda
Original Assignee
Univ Degli Studi Di Milano Bicocca
Univ Degli Studi Milano
Fond Irccs Ca Granda Ospedale Maggiore Policlinico
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Application filed by Univ Degli Studi Di Milano Bicocca, Univ Degli Studi Milano, Fond Irccs Ca Granda Ospedale Maggiore Policlinico filed Critical Univ Degli Studi Di Milano Bicocca
Priority to IT102019000004571A priority Critical patent/IT201900004571A1/it
Priority to US17/598,627 priority patent/US20220162611A1/en
Priority to EP20713010.5A priority patent/EP3947676A1/en
Priority to CA3135085A priority patent/CA3135085A1/en
Priority to PCT/EP2020/058571 priority patent/WO2020193709A1/en
Publication of IT201900004571A1 publication Critical patent/IT201900004571A1/it

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/113—Antisense targeting other non-coding nucleic acids, e.g. antagomirs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/323—Chemical structure of the sugar modified ring structure
    • C12N2310/3233—Morpholino-type ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT102019000004571A 2019-03-27 2019-03-27 Inibitore di miR-129 e suoi usi IT201900004571A1 (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT102019000004571A IT201900004571A1 (it) 2019-03-27 2019-03-27 Inibitore di miR-129 e suoi usi
US17/598,627 US20220162611A1 (en) 2019-03-27 2020-03-26 Inhibitor of mir-129 and uses thereof
EP20713010.5A EP3947676A1 (en) 2019-03-27 2020-03-26 Inhibitor of mir-129 and uses thereof
CA3135085A CA3135085A1 (en) 2019-03-27 2020-03-26 Inhibitor of mir-129 and uses thereof
PCT/EP2020/058571 WO2020193709A1 (en) 2019-03-27 2020-03-26 Inhibitor of mir-129 and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102019000004571A IT201900004571A1 (it) 2019-03-27 2019-03-27 Inibitore di miR-129 e suoi usi

Publications (1)

Publication Number Publication Date
IT201900004571A1 true IT201900004571A1 (it) 2020-09-27

Family

ID=67108017

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102019000004571A IT201900004571A1 (it) 2019-03-27 2019-03-27 Inibitore di miR-129 e suoi usi

Country Status (5)

Country Link
US (1) US20220162611A1 (it)
EP (1) EP3947676A1 (it)
CA (1) CA3135085A1 (it)
IT (1) IT201900004571A1 (it)
WO (1) WO2020193709A1 (it)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008010558A1 (en) 2006-07-20 2008-01-24 Panasonic Corporation Ultrasonic probe
KR20130083964A (ko) * 2012-01-16 2013-07-24 김승찬 시험관내 배양된 세포주 에 hsa-miR-129-5p miRNA에 대한 DNA antisense oligomer 처리 및 신호전달체계 변경 방법
CN107760685A (zh) * 2017-12-04 2018-03-06 石河子大学 长链非编码rna‑ror的应用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008010558A1 (en) 2006-07-20 2008-01-24 Panasonic Corporation Ultrasonic probe
KR20130083964A (ko) * 2012-01-16 2013-07-24 김승찬 시험관내 배양된 세포주 에 hsa-miR-129-5p miRNA에 대한 DNA antisense oligomer 처리 및 신호전달체계 변경 방법
CN107760685A (zh) * 2017-12-04 2018-03-06 石河子大学 长链非编码rna‑ror的应用

Non-Patent Citations (89)

* Cited by examiner, † Cited by third party
Title
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