IT7924316A0 - Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati. - Google Patents

Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati.

Info

Publication number: IT7924316A0
Authority: IT; Italy
Prior art keywords: purification; ursodeoxycholic acid; new derivatives; derivatives; new
Prior art date: 1979-07-12

Application number

IT7924316A

Other languages

English (en)

Other versions

IT1165252B (it

Original Assignee

Blasinachim Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-07-12

Filing date

1979-07-12

Publication date

1979-07-12

1979-07-12 Application filed by Blasinachim Spa filed Critical Blasinachim Spa

1979-07-12 Priority to IT24316/79A priority Critical patent/IT1165252B/it

1979-07-12 Publication of IT7924316A0 publication Critical patent/IT7924316A0/it

1980-07-04 Priority to DE8080103817T priority patent/DE3063603D1/de

1980-07-04 Priority to EP80103817A priority patent/EP0024292B1/en

1980-07-04 Priority to AT80103817T priority patent/ATE3641T1/de

1980-07-10 Priority to JP9338680A priority patent/JPS5632500A/ja

1980-07-11 Priority to US06/167,468 priority patent/US4316848A/en

1987-04-22 Application granted granted Critical

1987-04-22 Publication of IT1165252B publication Critical patent/IT1165252B/it

Links

RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 title 1
238000000034 method Methods 0.000 title 1
238000000746 purification Methods 0.000 title 1
RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 title 1
229960001661 ursodiol Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IT24316/79A 1979-07-12 1979-07-12 Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati IT1165252B (it)

Priority Applications (6)

Application Number	Priority Date	Filing Date	Title
IT24316/79A IT1165252B (it)	1979-07-12	1979-07-12	Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati
DE8080103817T DE3063603D1 (en)	1979-07-12	1980-07-04	Process for the separation of ursodeoxycholic acid from chenodeoxycholic acid and products obtained during the process
EP80103817A EP0024292B1 (en)	1979-07-12	1980-07-04	Process for the separation of ursodeoxycholic acid from chenodeoxycholic acid and products obtained during the process
AT80103817T ATE3641T1 (de)	1979-07-12	1980-07-04	Verfahren zum trennen von ursodesoxycholsaeure und chenodesoxycholsaeure und waehrend des verfahrens erhaltene produkte.
JP9338680A JPS5632500A (en)	1979-07-12	1980-07-10	Purification of ursodeoxycholic acid and novel silyl derivative of ursodeoxycholic acid therefor
US06/167,468 US4316848A (en)	1979-07-12	1980-07-11	Process for the purification of ursodeoxycholic acid

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT24316/79A IT1165252B (it)	1979-07-12	1979-07-12	Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati

Publications (2)

Publication Number	Publication Date
IT7924316A0 true IT7924316A0 (it)	1979-07-12
IT1165252B IT1165252B (it)	1987-04-22

Family

ID=11213071

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT24316/79A IT1165252B (it)	1979-07-12	1979-07-12	Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati

Country Status (6)

Country	Link
US (1)	US4316848A (it)
EP (1)	EP0024292B1 (it)
JP (1)	JPS5632500A (it)
AT (1)	ATE3641T1 (it)
DE (1)	DE3063603D1 (it)
IT (1)	IT1165252B (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1132055B (it) *	1980-05-14	1986-06-25	Erregierre Spa	Processo per la preparazione di acido ursodesossicolico ad alta purezza
IT1137459B (it) *	1981-04-14	1986-09-10	Erregierre Spa	Prodesso per la preparazione di acido ursodeossicolico ad alta purezza
IT1167479B (it) *	1981-07-24	1987-05-13	Carlo Scolastico	Derivati dell'acido chenodesossicolico
IT1167478B (it) *	1981-07-24	1987-05-13	Carlo Scolastico	Derivati dell'acido ursodesossicolico
JPS59159467A (ja) *	1983-03-02	1984-09-10	Toshiba Mach Co Ltd	非接触形メカニカルシ−ル
ATE303399T1 (de)	2001-03-12	2005-09-15	Intercept Pharmaceuticals Inc	Steroide als agonisten für fxr
KR100439069B1 (ko) *	2002-04-03	2004-07-05	노일근	초미립 침상결정형 우루소데옥시콜린산 및 그 제조방법
CN102766185B (zh) *	2012-08-02	2015-04-22	苏州天绿生物制药有限公司	一种从熊去氧胆酸废母液中分别回收熊去氧胆酸和鹅去氧胆酸的方法
CN107915767A (zh) *	2014-06-20	2018-04-17	华东理工大学	硅烷化技术纯化熊去氧胆酸的方法
CN105503987B (zh) *	2015-12-28	2017-05-31	成都市新功生物科技有限公司	一种载铜活性炭催化氧化还原法用鹅去氧胆酸合成熊去氧胆酸的方法
CN106520888B (zh) *	2016-10-28	2020-01-07	西安岳达生物科技股份有限公司	基于化学氧化和酶催化结合技术制备熊去氧胆酸的方法
IT202100019631A1 (it) *	2021-07-23	2023-01-23	Newchem S P A	Metodo per produrre estetrolo e i suoi intermedi

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3671555A (en) *	1969-03-05	1972-06-20	Jenapharm Veb	Trialkylsyliloxy-steroid compounds and process for making same
US3919266A (en) *	1972-09-21	1975-11-11	Intellectual Property Dev Corp	Production of bile acids
US3833620A (en) *	1972-11-16	1974-09-03	Intellectual Property Dev Corp	Production of chenodeoxycholic acid

1979
- 1979-07-12 IT IT24316/79A patent/IT1165252B/it active
1980
- 1980-07-04 EP EP80103817A patent/EP0024292B1/en not_active Expired
- 1980-07-04 AT AT80103817T patent/ATE3641T1/de not_active IP Right Cessation
- 1980-07-04 DE DE8080103817T patent/DE3063603D1/de not_active Expired
- 1980-07-10 JP JP9338680A patent/JPS5632500A/ja active Granted
- 1980-07-11 US US06/167,468 patent/US4316848A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IT1165252B (it)	1987-04-22
JPS5632500A (en)	1981-04-01
ATE3641T1 (de)	1983-06-15
EP0024292A1 (en)	1981-03-04
JPS617437B2 (it)	1986-03-06
US4316848A (en)	1982-02-23
DE3063603D1 (en)	1983-07-07
EP0024292B1 (en)	1983-06-01

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