IT8024230A0 - "6-piridazinoni utili come cardiotonici, e loro preparazione." - Google Patents

"6-piridazinoni utili come cardiotonici, e loro preparazione."

Info

Publication number
IT8024230A0
IT8024230A0 IT8024230A IT2423080A IT8024230A0 IT 8024230 A0 IT8024230 A0 IT 8024230A0 IT 8024230 A IT8024230 A IT 8024230A IT 2423080 A IT2423080 A IT 2423080A IT 8024230 A0 IT8024230 A0 IT 8024230A0
Authority
IT
Italy
Prior art keywords
pyridazinones
useful
preparation
tonics
heart
Prior art date
Application number
IT8024230A
Other languages
English (en)
Other versions
IT1141012B (it
Inventor
Lesher George Yohe
Dickinson William Borden
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of IT8024230A0 publication Critical patent/IT8024230A0/it
Application granted granted Critical
Publication of IT1141012B publication Critical patent/IT1141012B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
IT24230/80A 1979-08-30 1980-08-20 "6-piridazioni utili come cardiotonici,e loro preparazione" IT1141012B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7106579A 1979-08-30 1979-08-30
US06/144,576 US4304777A (en) 1979-08-30 1980-04-28 6-(Pyridinyl)-3(2H)-pyridazinones and their use as cardiotonics

Publications (2)

Publication Number Publication Date
IT8024230A0 true IT8024230A0 (it) 1980-08-20
IT1141012B IT1141012B (it) 1986-10-01

Family

ID=26751794

Family Applications (1)

Application Number Title Priority Date Filing Date
IT24230/80A IT1141012B (it) 1979-08-30 1980-08-20 "6-piridazioni utili come cardiotonici,e loro preparazione"

Country Status (19)

Country Link
US (1) US4304777A (it)
AR (1) AR226704A1 (it)
AT (1) ATA427680A (it)
AU (1) AU532052B2 (it)
CA (1) CA1155848A (it)
DE (1) DE3032137A1 (it)
DK (1) DK364880A (it)
ES (1) ES494559A0 (it)
FI (1) FI802676A7 (it)
FR (1) FR2464264A1 (it)
GB (1) GB2057438B (it)
IL (1) IL60918A (it)
IT (1) IT1141012B (it)
LU (1) LU82728A1 (it)
NL (1) NL8004815A (it)
NO (1) NO802507L (it)
NZ (1) NZ194811A (it)
PT (1) PT71736B (it)
SE (1) SE8005946L (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486431A (en) * 1981-01-14 1984-12-04 Sterling Drug Inc. Cardiotonic use of 4,5-dihydro-6-(4-pyridinyl)-3(2H)-pyridazinones
IL62679A0 (en) * 1980-04-28 1981-06-29 Sterling Drug Inc 4,5-dihydro-3(2h)-pyridazinone derivatives,their preparation and pharmaceutical compositions containing them
US4397854A (en) 1981-05-14 1983-08-09 Warner-Lambert Company Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
US4404203A (en) 1981-05-14 1983-09-13 Warner-Lambert Company Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
US4353905A (en) 1981-09-17 1982-10-12 Warner-Lambert Company Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones
IE54598B1 (en) * 1981-11-12 1989-12-06 Ici Plc Pharmaceutically-active pyridylvinylpyridazinones
US4591591A (en) * 1984-03-08 1986-05-27 Eli Lilly And Company Pyridazinone derivatives as inotropic agents
US4647564A (en) * 1984-05-14 1987-03-03 Eli Lilly And Company Inotropic agents
US4617302A (en) * 1984-10-15 1986-10-14 Eli Lilly And Company Inotropic agents
US4631279A (en) * 1984-10-15 1986-12-23 Eli Lilly And Company 6-(pyridinylphenyl)dihydropyridazinones as inotropic agents
HU195645B (en) * 1985-10-30 1988-06-28 Gyogyszerkutato Intezet Process for preparing novel 3(2h)-pyridazinone derivatives and pharmaceutical compositions comprising the same
DE3626865A1 (de) * 1986-08-08 1988-02-11 Boehringer Mannheim Gmbh Neue pyridazinon-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB9015764D0 (en) * 1990-07-18 1990-09-05 Fujisawa Pharmaceutical Co Pyrazolopyridine compound and processes for preparation thereof
CN1038249C (zh) * 1991-08-28 1998-05-06 罗姆和哈斯公司 含有二氢哒嗪酮及其相关化合物的杀菌组合物
EP3365335B1 (en) 2015-10-23 2024-02-14 Array Biopharma, Inc. 2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2h)-one compounds as inhibitors of fgfr tyrosine kinases
JP2022515198A (ja) 2018-12-19 2022-02-17 アレイ バイオファーマ インコーポレイテッド FGFRチロシンキナーゼの阻害剤としての置換ピラゾロ[1,5-a]ピリジン化合物
CN113474337A (zh) 2018-12-19 2021-10-01 奥瑞生物药品公司 作为fgfr抑制剂用于治疗癌症的7-((3,5-二甲氧基苯基)氨基)喹喔啉衍生物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3822260A (en) * 1970-10-09 1974-07-02 American Cyanamid Co 6-(cyanophenyl)-4,5-dihydro-3(2h)-pyridazinones
US3746712A (en) * 1971-06-08 1973-07-17 A Ross 6-(substituted-phenyl)-5-methyl-4,5-dihydro-3(2h)-pyridazinones
US3812256A (en) * 1971-06-08 1974-05-21 American Cyanamid Co Novel method for lowering blood pressure in mammals
US4004009A (en) * 1975-07-31 1977-01-18 Sandoz, Inc. Antihypertensive aryl pyrazolo[4,3-c]pyridazinones
US4072746A (en) * 1975-10-14 1978-02-07 Sterling Drug Inc. 3-Amino-5-(pyridinyl)-2(1H)-pyridinones
US4004012A (en) * 1975-10-14 1977-01-18 Sterling Drug Inc. 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones

Also Published As

Publication number Publication date
FI802676A7 (fi) 1981-01-01
NO802507L (no) 1981-03-02
IL60918A0 (en) 1980-10-26
IL60918A (en) 1983-11-30
AU6192880A (en) 1981-03-05
US4304777A (en) 1981-12-08
PT71736A (en) 1980-09-01
AR226704A1 (es) 1982-08-13
FR2464264A1 (fr) 1981-03-06
DK364880A (da) 1981-03-01
DE3032137A1 (de) 1981-03-19
NZ194811A (en) 1984-05-31
SE8005946L (sv) 1981-03-02
NL8004815A (nl) 1981-03-03
IT1141012B (it) 1986-10-01
ES8107215A1 (es) 1981-08-16
PT71736B (en) 1981-06-15
ES494559A0 (es) 1981-08-16
GB2057438B (en) 1983-09-07
ATA427680A (de) 1983-12-15
CA1155848A (en) 1983-10-25
AU532052B2 (en) 1983-09-15
LU82728A1 (fr) 1981-03-24
GB2057438A (en) 1981-04-01

Similar Documents

Publication Publication Date Title
IT8022284A0 (it) N-aril-ossazolidinoni e -pirrolidinoni, e procedimenti per la loro preparazione.
IT1085852B (it) N-fenil-n'-benzoil-ree sostituite,procedimenti per la loro preparazione e loro impiego come insetticidi
IT8024230A0 (it) "6-piridazinoni utili come cardiotonici, e loro preparazione."
NL7806208A (nl) 7 alfa-methoxy-7 beta-(1,3-dithietan-2-carboxamide) ce- falosporanzuurderivaten en de bereiding, alsmede de toepassing ervan.
IT7821444A0 (it) 1, 3, 4,-tiadiazol-2-il-uree, procedimento per la loro preparazione e loro impiego come fungicidi.
IT7922036A0 (it) 1,3-diaril-2-imino-imidazolidine e 2-imino-esaidro-pirimidine sostituite e procedimento per la loro preparazione.
IT1207271B (it) Amminoglicosidi, procedimento per la loro preparazione e loro impiego.
IT8023315A0 (it) 2-(3,4,5-trimetossifenil)-tiazoli 4,5-bisostituiti e procedimento per la loro preparazione.
FI801033A7 (fi) Menetelmä 2,6-diaminonebulariinien valmistamiseksi.
NL7906624A (nl) 3,7-digesubstitueerde-3-cefem-4-carbonzuurverbindingen en hun bereiding.
IT1124897B (it) Azolil-chetali,procedimento per la loro preparazione e loro impiego con microbicidi
IT7919651A0 (it) Prodotti microbicidi e procedimento per la loro preparazione.
IT7820221A0 (it) Impiego. prodotti microbicidi, procedimento per la loro preparazione e loro
IT7922035A0 (it) Alcossialchilidenidrazinopiridazine e procedimento per la loro preparazione.
IT7919650A0 (it) Prodotti microbicidi e procedimento per la loro preparazione.
IT7821653A0 (it) Prodotti microbicidi, procedimento per la loro preparazione e loro impiego.
IT7829638A0 (it) 2,4-diammino-5-benzil-pirimidine eprocedimento per la loro preparazione.
IT7823392A0 (it) 17 beta-idrossi-4-androsten-3-oni e procedimento per la loro preparazione.
FI803038A7 (fi) 2,5-diketoglukonihapon valmistus.
IT7830941A0 (it) Composti 1,8-naftiridinici e processo per la loro preparazione.
IT1091249B (it) I cicloalchilcarbonil 3 3.5 dialogenofenil imidazolidin 2.4 dioni particolarmente utili come fungicidi e procedimento per la loro preparazione
IT7920094A0 (it) Octaidro-indolo [2,3-a] chinolizine 1,1 disostituite, procedimento per la loro preparazione e composizioni che le contengono.
NL190120C (nl) 2,3-dihydro-4h-1-benzopyran-4-on-0-carbamoyloximen alsmede farmaceutisch preparaat daarvan.
IT7923000A0 (it) Arilalchil-e arilossialchil-fosfonati e loro preparazione.
IT8019098A0 (it) 3, 4-epossipirrolidine 1-sostituite e procedimento per la loro preparazione.